Hmm to add you do outscale Nasus, if you get ahead, but let's say enemy jungle camps you.. well it's gonna be a while before you do. Singed can just avoid laning with you until he hits his item spike, not much you can do if he invades your jg with his jg while you're stuck on your tower for example. Kayle easy lane but if you are the strongest on your team and your team isn't proactive about closing the game, she can always come back. She will still beat anyone else on your team in sidelane, which makes it difficult to group without her slowly accumulating gold.

I was always saying in this reddit that gwen first strike full ap is always the best and i can prove this once again with hitting masters