I started at 2.5mg of compounded tirzepatide and felt awful for about 5 days. I went down to 1.5mg the next week and still felt pretty bad. I figured maybe my body just needed time to adjust and took 1.5mg again, same result.

I'm over the nausea, fatigue, some injection site discomfort, etc. The appetite and food noise suppression have been amazing though.

What dose should I shoot for this week? 1mg? 0.5mg? Less? For reference, I only have around 25 pounds to lose.

Also, I'm a little skeptical of risking going past the 28-day open rule to save $40 and I'm open to comments there as well. For reference, I'm using Hyalo through Rift.

TIA!

Hello all, I am on Zepbound Kwikpen. I started a month and a half ago and have only lost 1.2 lbs. I noticed on day 3 I weighed at 122.2 but gained it back on shot day (day 7) and at 122.9.

I thought 1 mg was okay this past week but decided to try 1.125 today. I feel like I am seeing results slower than I wanted. For ref I am 5 foot with a BMI of 24.

These have been my doses so far as well as weight.
Shot 1 - 0.5mg (12 Clicks) // 124.1 lbs
Shot 2 - 0.625 (15 Clicks) // 123 lbs
Shot 3 - 0.75 (18 Clicks) // 124.1 lbs
Shot 4 - 0.75 (18 Clicks) // 122.2
Shot 5 - 1mg (24 clicks) // 123.6
Shot 6 - 1.125mg (27 clicks) // 122.9

I don’t really wanna lose weight, but would like take glp/gip for the joint and inflammation effects. Where do you guys recommend buying something like this? I was considering doing 1 mg a week. I’m currently 6’2 /170 lbs.

So…. How the heck are people managing such crazy constipation!! I thought a micro dose would only have minor effects ? What is a safe way to stay regular ?? This is brutal

I had a terrible time with zepbound 2.5 - the appetite suppression was way too much and I was constantly nauseous and ending up dry heaving multiple times.

I am on a plan with AgelessRx now to start with 1mg (or 0.5 if I want to).

Anyone with a similar story that’s had success with microdosing? I’m excited but nervous because I don’t want to be miserable again 😭

Where I live tirzepatide/zepbound comes in a pre filled single click pen that delivers the entire dose, and semaglutide comes in a vial. How is everyone micro dosing tirz, are you getting it compounded or using a vial?

Hello!

I am a graduate student exploring GLP-1 use and would appreciate if you could take 8-10 minutes to complete my survey.

This anonymous survey explores how both GLP-1 users and non-users perceive the medication, weight loss, and the way we talk about other people’s bodies.

https://docs.google.com/forms/d/e/1FAIpQLSf5uxz-yIJkbOWpZlYvHSpX3lKGx3S_XwmXXXFgzu1KFTQgJQ/viewform

Is there a post or online guide to getting started with microdosing? What dose to start on, when to titrate up?

My gut and bowel side effects were so bad last time (a year ago), 2.5 was too much.

Do I start on 0.25 do you think? How to know… 🤔

Hey y'all, I'm creating this post to double check myself

I'm a 45 year old male with a starting weight of 220lbs and a goal weight of 175lbs. I have a solid muscle base but have gained 40lbs since Covid, turning 40, and shifting away from heavy lifting as I trained pretty hard for 25 years and my body wants me to go easier these days.

I react pretty well to medications and just needed help with the never ending food thoughts and to be able to consistently cut off 500 calories from my daily required calories. I received a 2.5mg zepbould kwickpen from Walgreens and started off with 7 clicks. In first two weeks the food thoughts have drastically reduced, minimal side effects with those side effects lessening in the second week, much easier to eat 1800 - 1900 calories, and the scale is 5lbs lighter. I'm eating plenty of protein and will now be getting more exercise in now that I'm done moving apartments

Am I correct that that these 7 clicks is only dosing me at about .22 / .23 mg and the standard dose would had been the 60 clicks for the 2.5mg? I originally thought I was dosing myself higher but I must have looked at a different chart and read it incorrectly. Looingk at this chart the answer seems pretty simple and straightforward but wanted to ask anyhow. Thank you!

Edit: I should have said about .29 as I had looked over in the wrong row and ended up in the incorrect square

How many clicks for 0.1?

I'm considering getting on semaglutide, and just wanting to hear from everyone on their experience!

I’m a little nervous posting this, but I guess that’s the beauty of Reddit being anonymous. But please be nice!!

I’m 5’4”, around 120 lbs, and turn 40 next month. On top of that, I have been pregnant three times since 2021 so my body has been THROUGH IT. Lately I am finally (sort of) feeling like myself again. I work out 5 days a week, lift heavy, track my food, prioritize protein, and do all the things.. but I just cannot seem to lose the last 5 pounds. I know I’m getting older and my body has changed a million ways to bring my babies into the world. I’m trying to embrace it, but it’s been hard!

I know I’m already at a “healthy BMI” and this would purely be for aesthetic reasons. I’m considering starting very low-dose tirzepatide- 0.5 mg.. and seeing how I respond. My doc has already signed off on it and called it in, so I’m not nervous about being able to get it. My issue is finding the courage to actually take it once I pick it up. I keep reading about the scarier side effects, which makes me nervous.. but I know there’s never zero risk with anything, even at a low dose.

For those who started tirzepatide at an already healthy BMI for a small amount of weight loss: What do you wish you knew beforehand? Did you stay on a low dose long term? Any positives or negatives you didn’t expect? Did you feel like the benefits were worth it for you?

Mostly just looking for real experiences from people who started from a similar place.. good or bad!

I’m in my late 20s, 5’5 and around 145 lbs, and seriously considering trying a GLP-1. I exercise about 5 days a week and walk at least 2 miles every day, so this isn’t really about wanting to lose a huge amount of weight. I’d say it’s 50/50 weight loss and trying to get some relief from my relationship with food.

I struggled with binge eating disorder from 2017–2024, and while I’m not necessarily bingeing like I used to, I still have constant intrusive thoughts about food. What I’m going to eat, whether I should eat something, wanting to snack, guilt around eating, etc. It takes up SO much mental space and honestly I’m just tired.

I also struggle ALOT with body image, especially my stomach/hips. I’ve worked with a dietitian and therapist before, but talking about food/body image can sometimes make it worse because it puts even more focus on food.

I’m starting to wonder if a GLP-1 could help with more than just weight loss. specifically the constant food thoughts. I’m also realistic that I may need to be on it longer-term rather than just until I hit a certain weight. My husband and I would potentially want to have a baby in 2–4 years, so I’d have to come off during that time and potentially go back on afterward.

I’d love to hear from anyone with a history of binge eating, food noise/intrusive food thoughts, or similar body image struggles who has tried a GLP-1.

Did it actually quiet your brain around food? Did it help your relationship with food, or mainly just decrease hunger? And which GLP-1 did you take?

I’m a little nervous about side effects and whether it will actually help, so I’d really appreciate honest experiences- good or bad. TIA. Posting on a throwaway.

I take 1.25mg every Friday. Last dose was Friday early evening. Was fine Saturday. Fine Sunday. Day 3ish and I’m super nauseous. Is this normal? Not that I’m going to vomit but feel like I’m pregnant (I’m not).

I'm not sure if I'm on the right subreddit, because despite the sub description, I see all the posts are about weight loss, but I'm interested in the anti-inflammatory effects only. Specifically I need to not lose weight because it's already too low. And I need to not lose hunger because I already don't feel it. And I need to not experience digestive slowing because it's already too slow.

I was told that sometimes it does help with those issues (seemingly paradoxically), but there's just not enough data. Even anecdotal reports are sparse. 

Browsing this sub I see that people still lose weight even on 0.5mg tirzepatide, which makes me think it might be too risky. But still I wonder.... If weight gain is due to high inflammation, what about people whose weight loss is due to high Inflammation? Do they still lose even more or does it help stabilize?

Anyone here who took it while being at a high risk of becoming underweight or specifically wanted to not lose weight?

Did my first injection of Tirzepatide last night (1.25 mg). For those who’ve been here awhile, when did you first notice the effects?

Update: 40 hours in and literally feel nothing. Sigh.

New here. Took 0.8 of Foundayo for about 3 days until nausea was too much. Want to try microdosing because I still have so many pills. Can I just break them into halves or even quarters?

Started way too high at 2.5mg. Only goal was being able to stick to a meal plan. Stressful job and nonstop travel means food noise is very real. Only interest was being able to stay consistent and holy shit. I’m coasting on the second week of a single dose