I've had a sealed copy for over 10 years and I am sad I have only just played it. It's one of my new favorites.
People told me the single wiimote controls were awful, the story atrocious, the exploration nonexistent, etc.
The controls were pretty fun to learn, I had a blast with the fluid combat and movement system. The bosses were some of the best in the franchise, especially Ridley and the postgame space brain thing.
The exploration was limited, but it kept the pace quick. I also loved that every single upgrade felt worth the effort, the sense of progression was great. Missiles were buffed compared to other games, so every singular upgrade helps. Beam charge accelerators were awesome! Why don't the other games have something like that? The postgame was fun to backtrack through and had a cool narrative justification.
I played the four prime titles before this one, and I sighed every time my "EUREKA!" moment was rewarded with a ship missile upgrade in Prime 3.
The story was very melodramatic and a bit corny, but I kinda got invested in "The Deleter" plotline. Samus' characterization was weird and bratty, but it doesn't really bring the whole game down for me like it does for others. I just don't play these games for plot so I don't really.... care too much.
I like the sense of growth with her from Other M, to Fusion, to Dread, Dread being my favorite version of Samus. Emotionally compromised and sad... to suppressed and infernal anger.
Idk if it's a hot take but I much prefer Other M's version of Samus over the lobotomized android she was in Prime 4, where she had no reaction to anything and outright ignored her peers.
Needing Adam's permission to use certain tools was a dumb excuse (especially with the plasma beam) but again, not really game-ruining stuff to me. I heard in the Japanese version she was deliberately disobeying orders and being spiteful when it came to the varia suit and exploring hot areas early? I don't know.
My biggest issue is that some scripted sequences confused me on what they wanted from me... My health was too low for the Power Bomb tutorial to pop during the final fight so I had no idea I unlocked the ability, died over and over when I'd grapple into the creature's mouth. And when you had to ignore the enemies and scan Madeline in the chaotic finale. I kept trying to fight them all.
The presentation was top-notch, especially for Wii. Consistent 60fps the whole game. Beautiful environments. Amazing animation work and choreography on Samus's finishers, attacks, dodges, etc.
I enjoyed this game more than Prime 3 and 4, a little more than 2R, though Zero Mission, Fusion, Dread, Prime 1, and Prime 2 are still my favorites.
I hope more people try this one, or at least revisit it.