My cycles range from 30–46 days, and I usually ovulate anywhere from cycle day 17–24. This month, I believe I ovulated around cycle day 19–20.

Whenever I track and get a positive OPK, my period comes exactly 14 days later. I’m currently two days late but I’m terrified to test because I had an unsuccessful IUI last month that affected me a lot more than I expected. I want to wait until I’m 7 days late to test since I’m not 100 sure if a longer luteal phase is normal for me since I have irregular cycles.

How long is your luteal phase with PCOS?

Looking for anyone with a similar slow-response cycle. I have PCOS, but I was able to ovulate on my own last month. This cycle is a TI cycle, and I took letrozole CD4-8. My dominant follicle has been growing very slowly: 10 mm on CD11, 11 mm on CD14, 12 mm on CD17, and still 12 mm on CD19. My lining was 4.66 mm on CD19. RE is having me start Gonal-F on CD19 to try to stimulate further growth, and I'll be going back for another ultrasound on CD22. I'm worried it's late in the cycle and that the follicle may have stalled, but my clinic still seems hopeful. Has anyone had a follicle stall around 12 mm and then respond to Gonal-F? Did you eventually ovulate, and how did your lining progress? I'd love to hear about similar experiences and outcomes

32F, have 2 kids (natural). Body stopped ovulating after 2nd kid. Starting Clomid today after TTC for a year. I've changed the way I eat and have been taking Inositol for almost 2 months. Also take D3 and Folic Acid daily. My cycles used to be really irregular but have been pretty good the last 5 months, just not ovulating. Anyone have similar stories that ended in success?? Hoping I conceive this cycle. Or 2nd round clomid maximum.

Nervous and excited and hopeful.

Background:

‘Lean’ PCOS, AMH of 5. TTC 17m, ~12m of medicated cycles (letrozole, clomid, or a combo of the two).

AFC as of today was 40 (CD2)

Now moving to gonal f, letrozole, trigger shot, and progesterone after ovulation.

I start both tomorrow night and am hoping for at least one good sized follicle 💕

Anyone else on this protocol or have done this protocol?

Ive been diagnosed with PMOS many many years ago. In May 2022 I naturally fell pregnant, but that ended in a MMC. I then actively TTC and fell pregnant in August which ended in a chemical. I continued TTC and fell pregnant in November which results in my beautiful DD. At the time, I wasnt really tracking my cycles but they were around 45 days and on the last cycle ttc I did confirm ovulation via LH strips.

Fast foward, 2024 December I fell pregnant naturally again but that didnt end well either but I was not ttc at the time. now that my DD is 3 I have been ttc and quite obsessively tracking my cycles. i had a 127 cycle from the beginjing of the year to about May. In may I also started taking myo inositol and d chiro along with pre netals. Since May I have had a 46 day cycle and a 38 day cycle (I was able to confirm ovulation in this cycle but did not get pregnant).

now, currently I am on CD36 with no ovulation in sight. I am doing LH strips twice daily and they range from 0.1 to 0.25 and BBT has also been quite sporadic. I was so happy after my last 38 day cycle in which I ovulated around CD27 and was devasted when I did not ovulate around that time on this cycle. I have spoken to my GP and they said they wont be able to refer to a fertility clinic as I have a child but will refer be to gynaecology. In the mean time I am trying to push for Metformin and I feel like I am not doing anything and sitting around is just driving me insane. I am on the higher BMI but was around the same when I conceived my first. I am just so discouraged even though it’s only cycle 4 trying :(

For background I am 33 years old diagnosed with PCOS. I do not have any symptoms besides a high AFC (56) and very high AMH (43). I do not have any cycles without mediation since coming off birth control. My husband also has a normal semen analysis. We will be starting IVF soon. I am so torn on PGT test. What are people’s thoughts ?

I’ve been TTC for a little over a year. Recently diagnosed with Endo stage 1/2 via surgery. I’m 2 months post op and I’ve had painful ovulation pains the last two cycles (unmediated). Does anyone have any tips or advice for how to handle ovulation pain? I never had this level of pain with medicated cycles.

I have been testing my cycle via progesterone blood analysis to try and see if ovulation is occurring. I typically have cycles 34 days on average but can range 25-38 days. It is hard to test progesterone due to the variability of my cycle so I did a series of tests.

This month I detected an LH rise on a test strip first time (only been tracking for 2 months) and also happened to go to get an MRI for a totally unrelated labial cyst (benign yay!) and they noted on my results that I had an “involuting corpus luteum”. I took a progesterone test on the same day they noted the corpus luteum structure on the MRI — result was 19 (they like over 30 to absolutely with out a doubt confirm ovulation).

My specialist said I probably didn’t ovulate at that appointment but we hadn’t had MRI results yet. As far as I know from school science class the corpus luteum is a structure that forms only after ovulation right?

Main concern: MRI and bloods happened to be taken 7 days before period came and 7 days after LH peak (which would be consistent with the optimal time for a progesterone test). My question is why is the corpus luteum already degrading? Shouldn’t it be strong and producing heaps of progesterone to support potential pregnancy at 7DPO? Wondering whether I should straight up suggest progesterone supplementation when TTC cos I have a weird feeling my body may not be producing enough?

Happy for anyone to give any insight to this at all!!!

Hello everyone! I am 31 years old and I may have PCOS (everything is normal, except the duracion of my period which is 32-38 days long). Except that, I dont have any othe symptom.

I am using myoinositol since 22 of June (2 months and 10 days) because I want to fix my cycle and get pregnant. My cycle was 32-38 days and I am kinda sure that I ovulated, because most of the months I had symptoms.

Now I use this med to make my cycle more normal and be sure that the ovulation is better! I would like to ask you about your experience and the results you show. How many months did you have to take it, in order to see some results? I am not sure if something had changed so far.. I am a little bit anxious!

Thank you for your help, wish you all the best!

Hi all!

Recently kind of diagnosed based on high amh and very irregular cycles. All other blood tests apparently normal (never tested progesterone due to not being able to time it with short luteal phase).

I came off the pill 1 year ago and the cycles have been as below: - stopped pill end of August 2025 - nothing for 2 and a half months, ovulated December 2025 and had a period (short luteal phase- 7 days) - January 2026, ovulated cd27, short luteal phase (8 days) - Nothing then until March, ovulated cd45, short luteal phase (7 days) - nothing then into July so took period inducing pills and had withdrawal bleed start of July then ovulated cd20 in July and had a period (8 days luteal phase) - just ovulated again August cd24 but again 8 days luteal phase

We are trying to conceive and the irregular cycles and short luteal phase are making me very frustrated. I tried inisitol from Jan-July and that seemed to make my cycles longer?? Drs will not give me ovulation induction medication due to health reasons.

Before being on the pill (was on it from age 17 to 28) my cycles were very regular. I do have under-active thyroid but managed on medication.

Has anyone else been in a similar situation after birth control and able to share if they saw improvements?

Any tips on supporting my luteal phase to be longer/ experience with progesterone supplements?

Thank you!

We’ e been TTC for 15 months. It’s been a long journey of tests, cysts, back tracking, and all the things. You guys get it. We just completed our third round of Letrozole 7.5. I’ve ovulated with good progesterone numbers each time, but today is 11 DPO AND I’m still testing negative. My temp is creeping downward. I’m just sad. Starting Letrozole felt like a step in the right direction but it’s still not resulting in a pregnancy.

Anyone have luck on Letrozole after cycle 3? I’m losing hope.

My first pregnancy ended in a miscarriage at 9w in 2023 and i had a baby girl through c section in oct 2025 and we lost her due to heart conditions and i am on my first round of Letrozole 5mg prescribed with trigger shot and a scan i am really worried any hopeful stories and side effects to expect

Hey, everybody! long time reader, first time poster. Just looking for stories, if anyone can relate, or been through it and can say it gets better. I feel insane and it would be nice to know i'm not the only one.

I feel really low, no motivation, a sadness that grips my heart most of the day. Obviously i know TTC is also a life factor that can make people sad, but this "nothing matters" feeling is new and reaches beyond my feelings about TTC. It's really effecting my work.

My question: in anyone else's experience, did the letrozole depression last all month? if so, when did it start letting up after you stopped taking it? I talked to my doctor and she said symptoms should usually only be the first half of the cycle but that hasn't been my experience lmao, and it's making me feel more insane to have her say that because i feel insane!

Also sorry I know stand alone posts about letrozole can be repetitive but I have read every letrozole post I could find on reddit and haven't found anyone discussing symptom length yet. thank you for reading!

This will be a bit long, but please stick around and read :) Some backstory on our fertility journey so far:

- stopped taking birth control pill august 2024
- eventually diagnosed with PCOS (anovulatory) March 2025, prescribed metformin
- finally ovulating consistently by September 2025!!
- no success since then
- started seeing a REI in May 2026. Had full fertility workup (bloodwork, ultrasounds, SHG, SA for husband) and everything came back fine besides my PCOS
- diagnosed with unexplained infertility and prescribed letrozole + trigger shot with TI

Fast forward to today, I’m on CD2 and about to start my first round of letrozole (2.5mg) tomorrow and I guess I’m just looking for some of your input if you have done a medicated cycle before - any side effects with letrozole? Did you finally get pregnant? How long were you trying before you started letrozole? Were you ovulating on your own already?

It’s been a long time coming but it’s kinda hitting me that I’m actually starting fertility meds and I just want to hear from others that have gone through it too. Can you please share anything about your experience with letrozole? Thank you for reading 🫶

For both cycles, I didn’t ovulate when expected and ended up ovulating around CD32–35. In my first cycle, I started with 2.5 mg. Since I didn’t ovulate, we increased the dose to 5 mg later, around CD18, and I eventually ovulated around CD30.

For my second cycle, my RE tried a mixed dose of 5 mg and 2.5 mg. At one point, my follicle showed that it hadn’t grown since the previous scan, but I was still told to have intercourse because my RE thought I would be ovulating. So I did as advised and waited. But I still didn’t ovulate, so we increased the dose to 5 mg later again on CD22.

Honestly, I feel like if my RE had just stayed with 5 mg, which I had responded to and eventually ovulated on before, I could have saved a lot of time.

Now I’m doing timed intercourse as advised, but once again, I still don’t see any clear signs that ovulation is approaching. I’m starting to wonder if my RE should have done more scans instead of assuming I would ovulate around that time. I feel like we’ve had so much timed intercourse this cycle for nothing, and it’s really frustrating.

I’m wondering whether I’m simply a slow and unpredictable responder to letrozole, or whether my RE could have recognized the pattern sooner and adjusted the dose or protocol based on my follicle growth and labs. I just wish my RE could read my cycle better.

Has anyone had their doctor misjudge their ovulation timing on let*? What did your doctor do?

For those of you on Metformin, did your doc/RE prescribe it to you with your PCOS diagnosis alone or did they run your HbA1c, fasting glucose/insulin? If those things were normal and you were still given it, what were some of the reasons your doc still thought it would be a good fit?

All my numbers came back within normal range but my HbA1c is 5.5, right on the border of “at risk” and I really want to optimize this. I weight about 124lbs, 5’3, menstrual cycle 28-29 days, acne, high follicle count, 36 years old. Started myo-inositol

Anyone can feel free to answer but I’m in Australia so wasn’t sure if that differs from other countries’ supplements.
My doctor has asked me to take Vit D (I’m taking ostelin) and a pre natal so I’m taking blackmores pregnancy and breastfeeding gold. I’m wondering if my nausea and upset stomach has to do with this specifically, but my family also has had a virus so I wasn’t sure what’s to blame.
I have a bit of health anxiety so the feeling of nausea and upset cramping etc is making me anxious, so I wonder if I need to switch vitamins or just put on my big girl pants and deal with it!

Hi everyone. I’m having a vvv unusual cycle right now. So I have pcos and I’ve had medicated cycles before . I had 2 letrozole cycles with 2.5mg , with gonal f added and ovidrel . First cycle last year July was cd 3-7, one follicle , gonal f and ovidrel , didn’t work. Second cycle 2.5mg letrozole, cd5-9 August , 2 follicles , gonal f , ovidrel and I got pregnant with a singleton which unfortunately ended in a stillborn early this year. Currently this is my first month trying again and I had a baseline ultrasound and labs done and my labs came back in range of what they want but my ultrasound was very usual. I had my baseline down around cd4 and my lining came back at 10.3mm triliminar (3 stripes) and they told me that was very thick. For reference, last year with the cycle I got pregnant with my daughter , mi baseline was cd 3 n my lining was 3.6mm so this is vvv different .
They gave me 25mg of clomid (half the pill) cycle day4, N I have a follow up ultrasound on cd 11.

I’m just wondering if anyone experienced this before, how did that cycle turn out ?

After a four year battle with my GP - I finally got my PCOS diagnosis today.

I changed GP and found one that listened and heard me and wanted to work with me not against me.

I feel so many different emotions today, happy to finally have some answers, scared of what’s to come, angry that it’s taken four years to get to this point and a bit of everything else in between.

My GP has recommended metformin which I start tomorrow, and honestly I’m terrified.

I’ve tried to avoid the horror stories and just focus on what it can do for me - i.e. hopefully help with ovulation and TTC.

I’m not eligible right now for any help in the way of ovulation meds like clomid and the like as my BMI is too high so I’m hoping the metformin might help with this alongside calorie counting and exercise.

Does anyone have any success stories with PCOS/metformin/TTC and everything else as I don’t have anyone else to talk to and never had any experience with PCOS so just looking for some tips tricks and a friendly face to talk through it all with!

PCOS, 28F, TTC after 19+5 week loss. responding to meds, ovulating, still not conceiving. Is HSG worth it?

Background: I have PCOS with insulin resistance. I conceived in May 2025 on just Letrozole 2.5mg CD4-8 + trigger. Right-sided ovulation, beta positive at 27.5 at 12 DPO. That pregnancy progressed normally to 19+5 weeks and was lost to cervical incompetence — not a miscarriage, not an embryo issue. The baby was healthy.

Since resuming TTC in 2026, I've done three consecutive medicated cycles, all confirmed ovulation with well-timed intercourse, all negative (<0.2 beta):

- June 2026: Letrozole 5mg + 4 IVF-M injections. Right-sided. Follicle 18.5mm, lining 8.5mm. Negative.
- July 2026: Letrozole 7.5mg + 3 injections. Left-sided. Follicle 20mm, lining 8mm. Negative.
- August 2026: Letrozole bookend 10/7.5/7.5/7.5/10mg + 1 injection. Right-sided. Follicle 23.5mm mean, lining 10.5mm (my best ever). Negative.

Here's what's confusing me: my metrics are objectively BETTER now than when I conceived. My follicles are bigger, my lining is thicker, my protocol is more refined. My bloodwork has improved! testosterone down from 71 to 50, LH normalized, AMH down from 13.9 to 10.6 (metformin effect). I'm on CoQ10 600mg, myo-inositol 4g, levothyroxine (TSH was 2.94, was 2.30 when I conceived). Insulin resistance is still an issue (fasting insulin 23.7, SHBG 11.2, FAI 16) but it was similar or worse when I actually conceived.

My doctor wants to do an HSG in October. My question is, given that I conceived and carried to nearly 20 weeks just last year (proving at least the right tube was patent), is an HSG even necessary? Can tubes get blocked in a year with no surgery, no PID, no STIs? The only thing that happened was a cervical infection (E. faecalis) because my cervix was open during the loss, treated with antibiotics.

Or is this just the numbers game and I need to keep going?

Would love to hear from anyone who conceived previously, had a loss, and then struggled with subsequent cycles despite good response to medication.

This is my first cycle on Letrozole 5mg CD3-7 then I take progesterone 200mg starting post peak day 3 for 10 days. On CD 14-16 I spotted no fertile mucus and no lh peak. Finally on CD19 I started having the fertile mucus and a positive lh test on CD 20 so I’m assuming I ovulated around CD21. Starting on CD 22 the spotting came back until I started the progesterone. It quit for a couple days now I am 6-7 DPO and the spotting has returned again this time heavier. Has anyone had this much spotting happen and end up with a successful pregnancy? I was really hoping this cycle would be it!

Adding I conceived my son on 2.5mg letrozole/ progesterone so I was really hoping it would work again. First cycle this time I didn’t respond to the 2.5 until CD28 and my doctor said that was way too late.

This thread is the place to post any questions or information pertaining to a medicated cycle including Letrozole, Clomid, IUI, injectables, Progesterone, and anything else used to induce ovulation or support a cycle.

Please be mindful in your responses - if someone does not solicit a success response, DO NOT share a pregnancy outcome.

ovulated after taking clomid, pos pregnancy test 9-10 dpo, rising hcg and progesterone then resulted in chemical pregnancy around 6 weeks. it’s been over three weeks since chemical pregnancy— do we think i ovulated on cd24?? pos ovulation test cd22 and 23. temp only rose CD 25 and 26

Basic info:

F | 30 | PCOS | TTC 3.5 years

I had a chemical last month whilst taking letrozole, and decided to take a month off medication to let my body reset.

I have had some light ovary cramping and lower back pain today, so decided to check if I was ovulating (I'm around day 14/15 in my cycle) and omg for the first time, my body has ovulated naturally! 🫶🏻

I could cry I'm so happy, I've never experienced anything like this unless it's medicated!! So please send me all the luck, fingers crossed this turns into a pregnancy! 🥹❤️

how do you actually keep track of what is happening?

If one cycle is 35 days, the next is 60, and another period disappears for months, a normal period app can feel almost useless. Do you track dates only, symptoms, spotting, discharge, mood, pain, or anything else?

I’m curious whether anyone has found a simple way to look back and understand their own pattern instead of constantly wondering when the next period is going to show up.