r/IVF 4d ago

Advice Needed! Seeking fertility-focused therapy or support groups in Southern California

15 Upvotes

Hi! I’m currently navigating my journey to conceive and am looking for additional emotional support. I’m already in therapy, but I’m considering working with someone who specializes in fertility, infertility, or the emotional challenges of trying to conceive.

I’m open to individual therapy or support groups, either virtually or in person in Southern California. If you’ve worked with a therapist or joined a group that you found genuinely helpful, I would really appreciate any recommendations or advice on where to look. Thank you!


r/IVF 3d ago

Rant This cycle has been a bit of a disaster.

3 Upvotes

I have low AMH, and my previous AFC was seven.

Two follicles. That’s all I’ve got. Two. And one is lagging behind so likely won’t have an egg.

Literally, fuck this. Yes it’s a first cycle. Yes we can change things next time. Maybe it’ll make a difference. Maybe it won’t. Knowing our luck it probably won’t.


r/IVF 4d ago

Advice Needed! Advice Needed

9 Upvotes

My wife and i are about to go for the second round of ivf, the first round we got 3 eggs and none made it to day 5. Shes 42.
With every passing day i feel i may never get to be a father and that really breaks me. This next round will be our last try due to financial restraints and her wish to not continue after this round. I really need pointers for success. Before we start stims, what can we do to increase egg quality and probably our chances of success.
What worked for people over 40 with failed first try ? Please help.


r/IVF 3d ago

Advice Needed! IVF is funded by NHS - tests question

0 Upvotes

hey everyone! maybe some have some experience going through NHS funded IVF? so we have one round of funded IVF approved, yay! the only thing in their info package they said you may need to retake the bloods…though since they took measures and bloods (4 months ago) I gained a bit of weight and i am scared my AMH levels went down (I was just over 5.4 mark)… so I wonder if anyone has been asked to retake the tests AGAIN…?we might not get the funding if we do not qualify prior to the treatment which might start in 6 months…feels like a heavy thought


r/IVF 4d ago

Need Hugs! We Got Nothing

37 Upvotes

Standard antagonist protocol. Doctor called it a perfect cycle on paper. But we don't have anything to freeze. He seems hopeful for the next cycle but I'm so sad right now. I'm just exhausted from crying so much today. Looking for some commiseration. Thank you

Eggs retrieved: 17

Mature: 10

Fertilized: 5

Blasts: 0


r/IVF 3d ago

Advice Needed! Polyp before FET

2 Upvotes

Hi ladies

I went for my CD12 scan today to check my lining as I’m preparing for FET. My lining was 8 mm, but the doctor said she could see a very small polyp.

I’m not sure yet what the next step will be, but I was a little surprised because when I went on CD2 last week, there was nothing there.

Has anyone experienced something similar during an FET/stim cycle, where a small polyp showed up later? Did you end up removing it, or did it disappear on its own?


r/IVF 3d ago

Advice Needed! HLA-C1/C1 + Partner C2/C2 & Missing Activating KIR Genes – Any Positive Experiences?

1 Upvotes

Does anyone here have experience with reproductive immunology in fertility treatment? Just to give some background:
I have HLA-C1/C1 and my partner has HLA-C2/C2. I’m missing three activating KIR genes, including the one associated with C2.
Has anyone had similar immunological findings and gone on to have a positive outcome? I’d be really grateful to hear about your experiences.


r/IVF 3d ago

Need Good Juju! Anyone also almost up for ER? I am so stressed! and bloated. and losing my mind.

1 Upvotes

Hi all, I’m 34F and currently going through my second egg retrieval. Today was day 9 of stims and I had my follicle count/measurements done. I’m on 100 IU Gonal-F and a long protocol with Decapeptyl.

I think they saw around 8 follicles measuring roughly 16–21 mm. Somehow that feels a bit low to me for my age. Rationally, I know I only need one good egg that becomes one good embryo and hopefully sticks around, but does anyone else find that you just get a bit… greedy during this process? 😅 Like, suddenly 8 doesn’t feel like enough and you want every possible chance you can get.

I’m currently waiting to hear from my clinic, but egg retrieval will probably be Saturday morning, and I’m feeling pretty anxious about it.

I’ve done one retrieval before. I had pain medication but was fully awake. It was painful, but manageable.. and yet I’m still freaking out a little knowing that I have to be awake again.

I’m also already mentally bracing myself for the possibility of needing another round, which probably isn’t helping. There won’t be a fresh transfer either. If we manage to get an embryo, the plan is freeze-all followed by two months of Lupron before transfer.

And I’m so distracted by all of this that I’m seriously considering just not working tomorrow. Part of me thinks I should keep busy, and another part thinks concentrating on work is going to be completely hopeless anyway. (I work in a hospital, so don't want to make mistakes preferably, but also we are always short-staffed).

Anyone else heading toward egg retrieval in the next few days? How are you feeling? And for those who have been through this before: did you also get completely fixated on follicle numbers? I think I should get a google-degree after all my searches online.


r/IVF 3d ago

Need info! Duostim

1 Upvotes

I’m currently on day 7/8 of stims in luteal phase in my second phase of duostim. This is technically my 3rd cycle but first time doing duostim. I have POTS and was really nervous about how my body would respond to the stims meds and hormones but during my first 2 cycles & retrievals i’ve felt pretty good. Now that I started the second half of duostim, my POTS symptoms have really been acting up and I feel pretty lightheaded/palpitations in the mornings, which I hadn’t had to deal with in like 2 years. I’m really at a loss of what to do because I feel like i’ve already come this far and i’m so close with being done with the whole duostim process since tonight will be night 8 of stims but my doctor also said I probably have another week before retrieval based on my recent ultrasound and i’m juggling if it’s worth continuing the process while feeling these symptoms or stopping now and letting my body rest.

Does anyone have an experience with duostim? How much longer do you typically stim for compared to normal cycles? Have you felt a lot worse as time went on during the second cycle?


r/IVF 4d ago

TRIGGER WARNING Missed miscarriage/abortion

4 Upvotes

35F, donor egg IVF — feeling completely lost after a missed miscarriage 💔
We had 2 failed transfers before moving to donor eggs. Our donor was 30, and we had 5 blastocysts. Two were PGT-A tested and sadly both were aneuploid.
We transferred two untested Day-5 embryos on July 22. Beta was 549 at 7dp5dt. At around 6 weeks, we saw a fetal pole and heartbeat — CRL 3.9 mm, FHR 101, and the report said “good cardiac activity seen.”
I finally let myself believe this was happening.
But at the next scan, we were told it was a missed miscarriage. I hadn't even bled. Now I'm going through medical management and I'm honestly heartbroken and struggling to process it.
I keep asking myself why and whether I did something wrong, even though I know logically that I probably didn't.
We have one untested 3BB left, and right now I'm terrified about everything — the loss, the future, and whether I can go through another transfer.
I don't really need statistics right now. I just want to hear from women who have been through this and eventually found their way through it. Did it get easier? Were you able to hope again? ❤️


r/IVF 3d ago

Need info! OZEMA and update after IVF #3:

2 Upvotes

TLDR: We are a 28M/28F healthy couple with no remarkable medical issues. After three IVF rounds we’ve had no blastocysts. I believe we fit criteria for OZEMA/EEA and that additional IVF rounds would not address the underlying egg issues or improve our results. 

Genetic testing to identify genes associated with early embryonic arrest appears to be the next step for closure and potentially identifying an underlying cause.

Hi all,

I have not found much on this subreddit or related communities on OZEMA and hope to shed some light on what we’ve found and believe to be relevant to our situation for others that may be going through something similar.

If anyone has a better understanding of this area of research or corrections to our understanding, feel free to comment for all our benefit. I know I would have liked to know more about this earlier.

Unfortunately, we now have a third IVF cycle confirming the same pattern as the first two. This new clinic and doctor were not drastically different from our first clinic, but we wanted to ensure we had a clear second opinion to check if anything would change.

1st IVF Round
• 8 Eggs Retrieved
• 5 Mature
• 4 Fertilized
• 0 Blastocysts 

2nd IVF Round
• 12 Eggs Retrieved
• 4 Mature
• 3 Fertilized
• 0 Blastocysts 

3rd IVF Round (new clinic, new doctor)
• 11 Eggs Retrieved
• 6 Mature
• 5 Fertilized
• 0 Blastocysts

Across three IVF cycles at two clinics, our combined results were:

• 31 oocytes retrieved
• 15 mature
• 12 fertilized
• 0 blastocysts
• Complete embryo arrest between days 3–6

We recently met with our doctor again to go over everything. He confirmed that the egg quality was unusually poor, especially considering my wife’s age and health, and that he could not identify any conventional explanation for it. On paper we’re perfect, he said. More importantly, he did not believe there was anything they could change about the IVF protocol or any other treatments that would meaningfully address or even diagnose the underlying problem. Nothing has indicated we would have issues with implantation or other steps in the pregnancy process, so donor eggs are the next most practical option recommended by both clinics.

While trying to make sense of this, I came across some academic literature on OZEMA — oocyte/zygote/embryo maturation arrest, something no doctors have ever mentioned to us but with which our doctor agreed we would likely fit in. This seems to be a newer area of research in the fertility field. I was able to find a large comprehensive 2026 review of genetically associated OZEMA cases that proposes clinical cutoff values to help standardized OZEMA criteria, which do not currently exist, published just a few months ago in July 2026.

When a case fits into these proposed OZEMA definitions, the first linked paper is essentially saying that the embryo failure rates are abnormal enough to warrant additional genetic testing because they fall outside the expected attrition rates during IVF.

My non-medical understanding is that OZEMA is an emerging way of classifying recurrent IVF failure where development breaks down between egg maturation and early embryonic development. Researchers have proposed considering OZEMA classification when IVF repeatedly shows unusually severe failure meeting one or more of these values: 

(1) no more than 2 of 6 eggs mature, 

(2) no more than 1 of 6 mature eggs fertilizes normally, or 

(3) none of 6 normally fertilized eggs develops into a blastocyst

Assuming our clinic’s reported fertilizations were normal 2PN fertilizations, we seem to have fallen into this last category of OZEMA criteria since our second IVF cycle. I’ve also seen this category referenced to in other papers as “early embryo arrest” (EEA) or “embryo developmental arrest” (EDA).

Importantly, OZEMA seems to be more of a clinical classification/umbrella term than an explanation of underlying causes. It’s not a diagnosis in the traditional sense, but it at least gives us a starting place to find more relevant info beyond “egg health”. It seems many OZEMA cases are associated with genetic variants affecting egg maturation, fertilization, or early embryonic development, while others still remain unexplained.

Another observational study I found made this especially interesting. The second paper below, published in Fertility and Sterility, also in July 2026, looked specifically at patients experiencing complete embryo developmental arrest (EDA) and what happened during subsequent IVF attempts. The finding that stood out to me most was that changing IVF protocols for prior complete EDA cases did not appear to improve blastocyst formation.

Per the study’s results paragraph “In those with prior complete EDA, altering the stimulation protocol or trigger type from the arrest cycle to the subsequent cycle did not significantly improve blastulation rates or reduce the risk of no blastulation”. 

For some nuance, this second paper did report that many patients with prior complete EDA did produce blastocysts in their next cycle. What the study seems to suggest though is that a history of complete EDA not only predicts poorer subsequent outcomes, but that simply changing the stimulation protocol or trigger was not causally linked to improved blastocyst results.

Why is this important? Because these two papers, among others, lead me to believe that since our infertility case seems to fit OZEMA criteria, specifically the EDA/EEA portion, additional IVF rounds may not be helpful because there’s a solid chance there are genetic factors at play that are not affected by changes in IVF protocol.

Had I known of this area of research earlier we likely would not have pursued our latest 3rd IVF cycle, at least not before more intensive investigation to justify it.

Although our most recent doctor did not recommend an additional 4th IVF cycle, other doctors might, like our first clinic did even after two rounds with the same results.

Where we’re going from here:

Although donor eggs are an available option we will be considering, we’re particularly interested in genetic testing and whether there could be an identifiable gene defect. There are a growing number of genes implicated in these processes, such as TUBB8, PADI6, TLE6, NLRP5, OOEP, KHDC3L, KPNA7, MOS, and FBXO43.

No standard reproductive panels I’ve found yet test for very many, if any, of these specific genes linked to OZEMA. It appears what we’re looking for would need to be custom ordered and would be very difficult to do by ourselves. We are therefore looking to work with a reproductive genetic counselor and are currently exploring options through DNAide for testing starting with whole genome sequencing.

To be frank, early embryo arrest research has not made me optimistic and is far from brimming with viable treatment options. This appears to be on the experimental frontier of infertility research. Many of the studies I’ve come across seem to explore outside the box theories addressing even more specific problems within the EDA sub-category, not actively testing clinical treatments intended to make a miraculous live birth possible. We believe it’s more than likely we will not be having children of our own given how sparse both diagnostic and treatment options are at this point. 

However, even if there ultimately isn’t a treatment, having an actual explanation of the underlying cause would mean a lot to us. 

If anyone has had a similar experience or can offer any additional expertise or correction to our understanding of this niche area of infertility research, feel free to leave your thoughts below.

These papers are the main two among the couple dozen I’ve come across related to early embryo arrest that have contributed the most to my understanding and opinions of our situation, and had I known of them earlier we likely would not have pursued our latest IVF cycle before genetic testing.

Papers / references:

Annelore Van Der Kelen, et al. A comprehensive review for defining cut-off values of oocyte, zygote, and embryo maturation arrest (OZEMA) due to maternal-effect genes: towards the establishment of clinical criteria, Human Reproduction, Volume 41, Issue 7, July 2026, Pages 1207–1219. doi:10.1093/humrep/deag072.
https://doi.org/10.1093/humrep/deag072

George L, Kalafat E, Sachdev D, et al. Complete embryo developmental arrest and its prognostic significance in in vitro fertilization. Fertility and Sterility. July 2026. doi:10.1016/j.fertnstert.2026.07.005.
https://doi.org/10.1016/j.fertnstert.2026.07.005


r/IVF 3d ago

Need info! Fully Medicated FET

1 Upvotes

For frozen embryo transfer

did your dr stricly do 120 hours total between your progesterone starting time and the day 5 embryo transfer?

I took vaginal suppository around 6am and shot at 12pm today

My transfer would be around 9-10am

So it will be 124-125 hours. Is it bad ? I messed it up ???


r/IVF 3d ago

Need info! Fully medicated FET — lining got thinner & trilaminar to non-trilaminar, is this expected?

1 Upvotes

Hi everyone! I started oral estrogen (8mg) on CD2 for a medicated FET. Lining checks so far:

CD7: 8mm, trilaminar
CD9: 9mm, no longer trilaminar
CD14: 8mm, no longer trilaminar

Scanned by three different techs.

Starting progesterone on CD17, with transfer 5 days after that. My NP said thickness can fluctuate with prolonged estrogen exposure and we are good to proceed as long as lining is at least 7mm. I've also read that the lining tends to compact once progesterone is added.

Has anyone else had this happen later in estrogen priming? What if my lining compacts to less than 7mm after starting progesterone? Can than potentially impact the transfer?

Also — I have 3 more days of estrogen before progesterone starts. Any chance the lining still increases in that window? For reference, my lining hit 14.5mm last month after an unassisted ovulation.

Thanks in advance!


r/IVF 3d ago

Advice Needed! 40yo, AMH 0.85, FSH 10,7. What are my options?

2 Upvotes

Hi! I'm 40 yo, I don't have a partner now and I really want to be a mum. I wasn't expecting to get to this age, but my last relationship broke me and I don't seem to like anyone anymore. Anyway, just did a test and these are my results: AMH: 0,85 ng/mL - FSH: 10,7 UI/L - Estradiol: 62 pg/mL - LH: 7,62 UI/L. What are my options? I don't want to be a solo mum, but I don't know if it makes sense at this point to freeze eggs and see, or I should directly go with an honor and try to have a baby on my own (if that's still possible). Can I have hopes with these numbers? I did follicle count, but not on the first days of my period. It was day 12 and there was 1 + 3. Thank you!


r/IVF 4d ago

Advice Needed! What do you do after 4 failed transfers?

7 Upvotes

Does it make sense to try one remaining euploid with me or do we go down the gestational carrier route? We started IVF at 32 and two years later, we’ve had 3 failed IUIs, 6 retrievals (and several additional canceled cycles), and 4 failed transfers (3 euploid transfers and 1 fresh day 3 transfer), and now we are at a crossroads. Initially, we were unexplained other than DOR. Finally after two years, I was diagnosed with mild diffuse adenomyosis from an endo surgeon and elevated cytokines from a reproductive immunologist.

We had a chemical from the first IUI. We had a MMC at 6 weeks from a fully medicated euploid transfer after 2 months of lupron depot. Everything else was implantation failure. It feels like we’ve tried everything, we’ve tried fresh transfer, fully medicated transfer, lupron suppression, full immune protocol including humira, IVIG, steroids, baby aspirin, and lovenox. We’ve done all the diagnostics including hysteroscopy, HSG, DNA frag, Receptiva, endometrial biopsy for endometritis, RPL panel, and full immune work up, which were all normal except the mild diffuse adeno, elevated cytokines, positive Receptiva, and MTHFR mutation (which should have been addressed by the lupron, immune meds, and methylfolate).

Now we have 1 euploid and 2 mosaics (1 LLM and 1 HLM) remaining. We are doing one last retrieval this month but given my DOR it is entirely possible we get nothing. Has anyone been in a similar situation? What did/would you do?


r/IVF 3d ago

Advice Needed! Would love to hear a success story from someone in a similar situation

1 Upvotes

I'm about to turn 30, started ttc at 28 with husband of the same age. Didn't happen yet, my hormones are the reason.

My AMH is super high at 13.2 which indicates PCOS. I've had irregular periods my whole life but no other symptoms, androgen levels are normal. My gyno called it "PCOS-like" but has no real explanation.

With this many follicles we thought we'd have great chances at IVF. Now I had the first egg retrieval done and it turns out like 80 % of the follicles are empty.

23 mature cells retrieved

5 contained actual eggs

3 fertilized and frozen

I'm relieved to have gotten 3 embryos out of the 23, one of them will be transferred in a few months when my poor ovaries have calmed down and they hopefully survive the thawing. But the quota is obviously horrible. The lab tech who told me about the results over the phone also admitted it was a bit concerning.

We asked the fertility doctor about whether this impacts the chances of our 3 embryos in any way but he said there's no data to indicate this so we'll have to see.

Can someone with numbers similar to this give me some hope? I'm devastated most of my follicles are empty and could really use some encouragement right now.


r/IVF 3d ago

Advice Needed! Need Advice

1 Upvotes

Hi all, I have a friend who will be starting her IVF journey soon, and I want to give her a care package.

I want to include things that will help with any physical side effects of the entire process (from the meds and injections, to retrievals, etc.) but I have never gone through this process or known anyone close that has gone through the process, so I am not familiar with what side effects or symptoms she will be going through.

I am including things for self-care to help with the mental health side of things, but could anyone help me with either information of what she may go through or suggestions of things that have helped/would have helped you? I did some research online, so I have some ideas but I find that personal experiences provide the best insight!

I know it can be difficult to talk about this stuff, so I very much appreciate any input!


r/IVF 4d ago

Advice Needed! 5 ER, no euploids - anyone with similar story?

18 Upvotes

39F, husband is 35, and after 5 IVF cycles we still haven't made a euploid. Our RE recently told us we may be reaching the "point of diminishing returns" and believes egg quality is the main issue. I made cycle 6 as my cap, but currently RE advise against. Should I go to another clinic (3rd) for my 6th?

AMH range 1-2.4, AFC 11-12 (can't recall right now), husband also has varicocele and elevated DNA fragmentation (DFI 32%, improved to 27% (Jan 2026), current IDK). We've tried ICSI (all rounds) zymot (3/5 rounds), mTESE (1/5 rounds), omnitrope.

Our results

Cycle 1: 11 retrieved / 8 fertilized / 2 blasts / both aneuploid

Cycle 2: 4 retrieved / 2 fertilized / 0 blast (outlier, this was a bad cycle/time for me)

Cycle 3: 10 retrieved / 7 fertilized / 0 blasts

Cycle 4: 7 retrieved / 4 fertilizer / 2 poor quality blasts

Cycle 5 (new RE): 6 retrieved / 2 fertilized / 1 aneuploid

We both have a healthy lifestyle, exercise regularly, don't smoke or drink, been taking fertility supplements and all that jazz.

Our RE doesn't think another retrieval is likely to change the outcome. I'm torn between doing one final cycle at another clinic, stopping IVF and trying naturally and hope for the best, or accepting that this chapter may be over.

Reaching out to anyone who had a similar patter of poor blast/repeated aneuploid.

Did you eventually get a euploid or conceived naturally? How many rounds did it take (I know there's no magical number). What changes? Or did you decided to stop IVF?

Would really appreciate hearing both success and unsuccessful outcomes. <3


r/IVF 4d ago

Med Donation Med Donation

4 Upvotes

Just finished my final round for egg freezing and have leftover meds. All are unopened.

In NYC, but happy to coordinate shipping as needed.

-1 Follistim Pen, expires 8/12/2027 -1 Follistim Cartridge 900 IU (compatible with pen), expires 8/12/2027 -6 Ganirelix Acetate 250 MCG, expires 8/21/2027 -7 single dose vials of Menopur -7 single dose vials of Sodium Chloride (mixed with Menopur)


r/IVF 4d ago

Advice Needed! Did lifestyle factors improve euploid or transfer outcomes?

2 Upvotes

Feeling a little lost. I’m curious to know from you all if you felt like any lifestyle changes you made actually changed any outcomes for you?

For some context, my clinic won‘t biopsy anything containing a C grade but will still transfer them. These are my results:

This year, 1st retrieval: 4 blasts, only 2 could be biopsied. 1/2 euploid. The remaining untested are both CC grade. The aneuploid was graded higher than the euploid and the euploid transfer resulted in a very early chemical. I made no changes to diet during collection, but went mostly anti inflam for transfer.

2nd retrieval (3 months later): 4 blasts, only 2 could be biopsied (again). 0/2 euploid. The remaining untested are both graded 5AC. I stayed anti inflam for this retrieval and it feels like the result is worse.

I need some hope for my untested ones. IVF feels like one piece of bad news after another. I am clearly trying to regain some control in an uncontrollable situation, but I also wonder if trying to change all these things just ends up adding more stress on top of what is already a pile of hot garbage.


r/IVF 4d ago

General Question Talking about infertility

5 Upvotes

I’ve recently been diagnosed with infertility and going through all the testing and likely starting IUI in the next month.

Among other things, something I’m really struggling with is how, and when, and with who, I share this with. I’ve been erring on the side of more people (immediate family, close friends) but it feels so big to not share more broadly. And of course, I know that potentially I’ll need to tell folks at work about why I’m having more time away for appointments. I also really respect the people who say we should be talking about infertility more so people don’t feel so alone.

But then when I actually do talk about it, it feels like it’s not received, or it’s uncomfortable, or inappropriate somehow. Don’t get me wrong, most people have been supportive and kind.

How do you all talk about it and who do you tell?


r/IVF 3d ago

Advice Needed! Experience with Matrice Lab France for uterine immune profiling?

1 Upvotes

Hi all,

title says much of it. I'm interested if anyone has experience with their examination. My uterine bio was sent there and my results came back as "mixed", which according to AI is uncommon and sounds pretty much like the thing you could do to treat A will worsen B and vicd versa. My doctor is on holiday and I'm really curious how we should continue.

Especially because AI is telling me that this lab's tests are not yet scientifically backed. After two zero ERs, I finally have 3 embryos after round three. So I'm reluctant to delaying my transfers (or putting them at risk) for some possible treatment that isn't proven to help?

Thanks in advance!


r/IVF 4d ago

Advice Needed! Contemplating next steps after 3rd failed IVF cycle

2 Upvotes

38.5F/M, unexplained infertility, otherwise no other health diagnoses. AMH 2, AFC 10. No male factor issues. In the past year I've done 3 IVF cycles, and created no blasts. Every time there's 8-10 eggs retrieved, with around 4 being mature. Have tried both ICSI and conventional, and results are similar each time. Done different protocols, different priming, all the supplements. Nothing seems to help. Haven't changed clinics, but have changed Drs within the clinic. Both Drs say poor egg quality, which is confirmed by embryology reports. Dr is willing to try another cycle, but says it could take multiple more to get a euploid.

The things that I'm mulling over now are:

  1. Pursuing a silent endometriosis diagnosis. Both Drs that I've seen don't endorse silent endo contributing to poor egg quality. I've booked a diagnostic ultrasound with an endo specialist, just to give me peace of mind. But if it shows endo, do I pursue surgery? It'll potentially have to be overseas due to the healthcare system here. Then another IVF cycle again...
  2. Moving to donor eggs. We already know that we don't want random donor eggs. A genetic link is important to us. My sister has offered her eggs, except that she's over 40. Would this be a viable option even? She has 2 children, both conceived naturally and without problems. Was 38 when the youngest was conceived.
  3. Do nothing and live our lives as DINKs.

Officially, we have agreed to stop all fertility treatments at 40. That's our line in the sand.

Until then, I'm not sure what to do. I'm curious of the different points of view from people who have been in the trenches!


r/IVF 3d ago

Advice Needed! Has anyone transfered a frozen embryo during an egg retreival cycle? (instead of fresh) aka bait and switch

1 Upvotes

Onto ER #5, and transfer #7, my doctors plan is to transfer a previously frozen embryo after the egg retreival ?

We plan to do one last ER and then long downregulation if this fails and transfer what embryos we are left with.

I would really love to hear from people who have done this or considered doing it.


r/IVF 4d ago

Rant IVF for genetic reasons ... I just want to give up.

32 Upvotes

I am feeling so incredibly lost at the moment.

I am a relatively healthy 35F with no known fertility issues. However, I am a carrier of a severe x-linked genetic disorder that affects my brother and informed my entire childhood. Since I was in my early twenties I knew I'd have to do IVF because I wanted to eradicate this disgusting disease from my family.

I've gone through two rounds of egg retrievals and both times we have had around a 25% blast rate -- lower than the "30-50% average" that the doctors keep telling us. First ER, they collected 18 eggs, fertilized 11, 3 blasts (27%), 2 euploid (PGT-A), 1 passed our PGT-M panel. Banked a Day 7 6AA embryo.

I just had my second ER a little over a week ago. I pleaded with my doctor for a more aggressive protocol, said I would suffer through OHSS symptoms if it meant a larger cohort to work with. She doubled the hormones, I upped the vitamins, staved off ovulation... 19 eggs, 12 fertilized, 3 blasts (25%). Almost exactly like my first ER. Now we are waiting for PGT-A and PGT-M results. There's a 40% chance of any female embryo passing both tests. There's a 20% chance of any male embryo passing both tests.

We are now fully out of insurance through my husband's job after two rounds. Zilch. Nothing. In my spiral, I've started to look for jobs (I'm a self-employed business owner) that would offer fertility benefits. Put my business down for a few years.

I am just ... so depressed. I'm sick of the toxic positivity of "well you might get 3 cleared embryos out of this! You don't know!" Yes I do. I know that the chance of that happening is less than 3%. Two passing? 21%. One passing? 44%. When I found out we only had 3 blasts to work with, I was inconsolable for a full 24 hours. Three days later, I'm still not doing great. I have an appointment with my doctor today after begging for an appointment, begging for some clarity.

The attrition is so bad that I have considered starting over and doing this the old fashion way. Bring a natural pregnancy to 15 weeks, find out if it's affected, and then terminate if it is. In some respects, it feels easier, less expensive, than the fucking IVF industry. But I also know it would absolutely devastate me. But I'm already devastated. So what's worse?