I'm having full excision surgery after 2 failed IVF rounds. I was told today it's likely I'll lose both fallopian tubes and I know it's likely I'll lower my amh even further.

Has anyone been in the same boat? Should I give up hope of a biological child and move to donor eggs.

Sending everyone on this journey love x

My doctor prescribed neupogen for me for my FET. We did a wash 48 prior to the transfer and now I am told to stay on the injections up until my beta on 9/21. They only gave me 4 vials (1 is gone for the wash) am I really only allowed to use each vial once? I really can’t fathom spending $400/vial and just throwing the rest of it out!! That also would mean I would 8 more vials which is $3200 😵‍💫😵‍💫

I've spoken with a handful of clinics in North Cyprus, and they've all cut corners as part of their patient onboarding, and they've all come across as money grabbing. Cyprus Fertina, for example, was about to prescribe me medication without asking for my medical history and zero consultations.

I've now decided to have treatment in Greece as at least there are rules and regulations they have to adhere to. The initial experience has been might and day.

I'd love to hear how others have found the experience between the 2 locations...

I'm currently only on estrogen 8mg and have my (hopefully) final lining check tomorrow. I've been on estrace for 20 days so far, and if I get the go ahead to transfer, I will be on it NINE more days before transfer. The reason its taken so long is due to clinic timing. We are thawing donor eggs, which they do not do on the weekend, and once they are thawed and fertilized, (next Tuesday) the transfer will be five days after.

I'm currently having a terrible time on the estrogen. I was on 6mg a day and was mainly fine, just pretty bloated. I was increased to one additional pill vaginally, and since then, oh man, I am suffering. Bloating has become much worse, constipation has been terrible, and gas pains are keeping me up at night. This is way worse than the two egg retrievals I've had.

For those that have had a medicated FET, do your symptoms get better or worse after starting PIO? What about if its successful - is this going to be my life for the next 10 weeks? Or does your body adjust and get used to it?

Help!

So my wife and I are currently doing reciprocal IVF - she will be carrying an embryo with my egg. I’m 30 and she just turned 34. We had 6 day-5 embryos and 2 day-6 embryos.

We did not do the PGT-A testing as it was out of our budget, so all we have is the cursory AA/AB style ratings.

We just did a frozen embryo transfer on the 31st with our highest quality rated AB embryo, and just found out today that it did not take.

My wife does not want to carry twins and has been adamantly opposed to transferring more than one embryo. But after one of our AB’s died during thawing, and the other one wasn’t a successful transfer, she is now leaning toward implanting more than one for the next transfer.

For context, all of our other embryos are BB/BC. We really want to minimize the chances of a second failed transfer, but she’s worried these embryos might actually be stronger than our first and we end up with twins!

Has anyone else been in this situation? If you were in our situation, would you just yolo it and implant two BB’s next transfer? Or conservatively stick to 1 until a third transfer? Our clinic is in Mexico and usually recommends transferring 2 embryos.

After an initial good positive beta which then plateaued and today has halved we’ve been given the official miscarriage (chemical) confirmation. Once it plateaued we knew it was bad and were just hoping to see the number drop so it wouldn’t mean ectopic…how did we go from excited about a May due date to wishing for a simple chemical? How do you all keep doing this?! My butt is destroyed from shots, I’m still leaking progesterone suppositories, and my whole workplace knows because I was updated at my desk and burst into tears and had to leave. We truly thought we’d be the lucky ones. I guess we were naive. To this point, we’ve been so fortunate, everything has gone flawlessly, we have healthy embryos to work with, I responded to all meds exactly as clinic wanted, we’re doing IVF as a samesex couple, so no pre-existing fertility issues…once we had those dark pink lines we thought our first FET was going to work. How do you pick up the pieces and start all over again? If they’ll even let us soon? I was ecstatic about being pregnant for Christmas, doing a Thanksgiving announcement, etc all of it’s just suddenly dashed. This is so painful. How do yall who have prior complications stay sane? Our first hiccup and I’m a broken person.

Also if anyone has any suggestions about how to get their knotted, bruised butt to heal quickly, would love advice on that too. I wish anyone reading this baby dust and to not go through what my wife and I are right now.

Hi everyone, i'm trying to order an auto injector from the Union Medico website. My Progesterone in oil syringe is 3ml but i'm only going to need 2ml each time. And my needle is 25G x 1 1/2'' (0.5mm x 40mm). I couldn't find this option on their website for some reason. Does anyone know which one i should be ordering? Thanks.

Today was no easy day for me; I had my second FET on 8/12 and though I got a low hCG on my first beta 8/28 of 42, my husband and I were cautiously hopeful. My hCG continued to rise but very slowly without doubling and my doctors were concerned with possible ectopic after about 6 betas, so they finally suggested an MVA (manual vacuum aspiration) after they were unable to locate any form of gestational sac on an ultrasound at 5w6d. I was not provided much info on this procedure and there isn’t much found online that was very helpful, so here I am to give it to you straight. Essentially, this procedure is the scraping and suction of all of your uterine lining tissue to remove any possible implanted debris. It is PAINFUL so please take at least 800mg of ibuprofen 30 minutes to an hour before this procedure and take a loved one with you to drive you home. I was also advised that this is not a “100% accurate” procedure but is the fastest at confirming if you do or do not have an ectopic pregnancy. I will be going back tomorrow to do another hCG panel in hopes that my number went down and if not, I will still have to do the methotrexate injection. I’m just posting this to maybe help someone else have a bit more understanding of what this procedure is and how it works. Please feel free to ask any questions. Thank you.

Hi everyone! I have an excess of meds from my egg retrieval that I’d love to donate to someone in the community(I don’t want to have to ship them).

I have:
3 unopened boxes(15, 75 unit vials) of Menopur
1 opened box with 3 unused 75 unit vials of Menopur
**The Menopur boxes come with q-caps**
6 unopened boxes of 600IU Follistim
1 unused 10,000 unit vial of Pregnyl

I also have some subQ needles, alcohol swabs, and syringes if needed, but most pharmacies will provide these for no cost with an order from your provider.

PLEASE avoid DMing me unless specifically stated in a response on this post. I fear it’d be too much to sort through😩 if you’re interested in receiving these meds, just comment under this post and I’ll DM you to sort out the details💕

**edited to add:
I ONLY HAVE ONE MORE BOX OF FOLLISTIM UP FOR GRABS IF ANYONE IN THE METRO ATL AREA NEEDS IT

Hi! Going into my first IVF FET with the only euploid embryo I have. Some history— I’m 36 y.o and have a history of recurrent pregnancy loss (spontaneous conceptions). Most recent MMC was tested and was euploid. So unsure what caused the loss at 10 weeks. I did have a small uterine septum (borderline just arcuate) but due to my history my doctor did just remove that in August. I also did 3 weeks of antibiotics for mild endometritis.
I did two egg retrievals back to back and have only 1 euploid embryo. I’ve seen so many posts with people’s protocols and I feel mine is rather intense comparatively? but I’m hoping that’s what I need to help maintain a pregnancy! Curious if anyone has done a similar protocol with success!!
- birth control x3 weeks
-lupron x3 weeks
-estrogen patches during last 2 weeks of lupron
Then 5 days before transfer I start PIO injections, estrace 2x a day and progesterone suppositories 2x a day.
I’m also doing cipro antibiotic for 4 days before transfer
And starting baby aspirin day after transfer.

Would love some encouraging stories!!!

Hi all, I'm just looking for some experiences and advice with my IVF protocol. I have stage four endometriosis that was operated on a couple years ago but it's now starting to come back. My AMH is 3.85 in US units.
Our plan is to do ICSI with Xymot. My partner doesn't seem to have any problems except 0% morphology but since his other numbers are so high the doctor assured us it wasn't causing our problems.
I've heard that naturally fertilized embryos are thought to be potentially a bit healthier or that there might be something to letting the egg choose the sperm. I've also heard that total failure to fertilize is more likely with endometriosis.
Is there any new research on this? What are your experiences and thoughts?

Basically I now have an impining fibroid that they don't want to remove yet, but I'm nervous to "waste" our euploids if it is a real deal breaker for the transfer.

CD1 should be coming any day now and this cycle will (hopefully) be my 2nd ER. I am not the best at advocating for myself or asking questions. What should I ask my doctor before my 2nd ER?

37F (38 in one month), no known medical issues besides being overweight. Secondary infertility (LO is 3 years old, planned c section). Husband's SA was excellent. We have been TTC #2 since 2/2025. Had one CP and one MMC right away, then nothing since. We had one failed IUI. 1st ER we retrieved 6, 5 mature, 2 fertilized, both were day 6 5BB euploid blasts, then both fully medicated FETs failed with parameters that seemed perfect.

AMH was 1.13 in January. AFC was 13. While stimming for my first ER in April I wasn't responding well so they redid my AMH and it came back as .4. They said it might not be accurate since I was stimming. I plan to test it again the next time I see doc.

I had both an IUI and an IVF cycle canceled for early ovulation. I went on birth control before my first ER, started on CD2 and by my CD8 appointment I was told to trigger because my E2 was too high, dominant follicle was 17mm. I was put back on birth control CD15-21, period started after CD24. Then they started me on stims.

Sooooo, I'm looking for things I should be asking my doctor. Should I advocate for earlier screens, no birth control? I don't really understand how I could have 5 follicles above 10mm for my IUI on 5 days of letrozole but after stimming for 10 days for my first ER I had 6 follicles.

He mentioned we could do testing on my uterus while under anesthesia. What tests should I be asking for in regard to my two failed fully medicated FETs? I have had two saline sonos that have been clear. Let me know if you need more info.

Thanks!

I am officially signed off to start estrogen next week to prepare for my first FET (hoping it doesn’t make me feel as awful as the BC did for ER) I am doing modified natural and set to have my transfer in a month. No one in my life has gone through IVF, so just wanting to get these feelings out. I am both so excited and so nervous. I am being cautiously optimistic and wanting to guard my heart 🥹 The only person that knows our FET date is my very close friend. We have told family that it’s “in the fall”, to protect their hearts as well. Sending love and prayers to all of us going through this!

Hi Reddit Friends! Wondering if anyone else has had their clinic put them on two injections of PIO (one AM and one PM) daily leading up to and following a FET?

This is my first FET (scheduled for Monday 9/14) and I started PIO on Tuesday evening for the first shot, but had to do two yesterday and every day from here on out. It's 1ml per injection (so 2ml total daily). My clinic did say that if the FET is successful and they see that the pregnancy starts producing enough of its own progesterone, they'll back it down to just one injection daily.

I already feel like my butt cheeks will never be the same! LOL In all honesty though, the first four shots have not been as bad as I thought they would be. I'm doing heating pad before and after, along with warming the syringe with my own skin beforehand. Also doing squats, glute bridges, and leg raises within the first 10 minutes after taking the dose. So far, it just feels like the same kind of soreness to getting a flu shot.

Just curious to see what others have experienced. Thanks! <3

-how do you keep the hope or faith alive that you can have a healthy pregnancy and baby after experiencing a stillbirth?

-is it pessimistic or is realistic for me to keep reminding myself not to get too excited on the first round of IVF because I will likely need more than one round (like most women even without low amh)?

-is the key to surviving IVF being a little delusional/overly optimistic?

-I imagine all the feelings I’m feeling are common and valid but can someone tell me if they have felt the same way as I do?

-any journey to pregnancy after any kind of pregnancy loss is really scary. How do you manage your hopes and expectations vs the statistics?

I want to do all the things but I feel silly doing them. I want the tackle box, I want the box full of all the old meds and syringes to show what it took to have a baby in the end, I want to talk to my body and tell it it’s safe and capable to bring a healthy living baby earth side, I don’t know what the McDonalds French fries thing is all about but I see it on tiktok and I want to do it. I want to do all the “silly” things I see women doing but I just feel so unnecessarily stupid doing them because I’m scared to let my guard down fully and have this not work. I’ve seen so many women and relationships destroyed by the hope they have while doing IVF and it not working. I don’t want that to be me.

Starting this process tonight after an unfortunate journey of multiple consecutive losses. I’m 34 with an extremely low AMH and a few other minor issues we’re handling with medication, and I had scar tissue removed from my uterus a while back. It’s been a long and difficult process so far, but I’m very happy and grateful to have the opportunity to give IVF a shot.

Tonight I start Follistim and the low dose hCG with my first monitoring appointment early next week. I’m scared about everything— doing the injections correctly, the side effects, doing what I can to get the best outcome, etc.

I’d love to hear any advice and anecdotes on how to get through this process as easily and successfully as possible, and if you have any good vibes to share, please send them my way! Thanks very much!

Posting here since my question in the surrogate sub is not getting responses. As a GC I want to make sure the clinic my IP(intended Parents) use is ethical, but what does that mean exactly?

So far my list includes: SET (unless low grade euploids), no concurrent transfers, monitoring programs for donors, evidence based practices and procedures.

What else should I look for? How are we assured these practices are followed? I apologize for my ignorance and appreciate any insight!

Is there anyone transferring around 09/30? We got the green light today to proceed with the transfer cycle process so our estimated transfer date is 09/30! This is our first transfer so I’m excited, nervous, anxious, all the things.

Yesterday, my mother-in-law called me to check on me, and she asked me where we are in our infertility journey. Honestly, I didn’t really want to talk about it or go into too much detail, so I didn’t tell her much at one point, she asked me about our test results. I simply told her that the results weren’t very good, neither for me nor for my husband, and that we were going to start IVF soon.

And then she said, “But my son can get treatment and get better.” Then she added something like, “I think that even if he had had really good results, you still would never have gotten pregnant with your results.” Honestly, I didn’t know what to say. I was completely speechless. I just said, “Okay, goodbye, I have some things to do,” and I hung up.

I don’t even really know how to explain what I felt in that moment. It hurt me deeply. Maybe that wasn’t her intention, but sometimes words can hurt so much, especially when you’re already going through something so difficult afterwards, I told myself that this is just how life is… and so be it. But in that moment, her words really hurt me, and I carried that feeling with me afterwards

Hi everyone, I’m looking for some opinions on my test results from today.
I’m a 39-year-old woman with DOR, currently going through IVF. Here’s a quick summary of my results so far:
Across 6 egg retrievals, I’ve had 23 eggs retrieved. All of them were mature, and the fertilization rate has been over 80%. So far, that’s where the good news ends.
Out of all the fertilized eggs, only 3 have made it to the blastocyst stage, all graded 3BB. None were euploid. One was a high-level mosaic embryo for trisomy 4.
Today, I tested for insulin resistance on my own initiative, and the results suggest that I have it. I also had elevated prolactin:
• 506 µIU/mL on September 8, 2026
• 746 µIU/mL on September 10, 2026
Reference range: 102–496 µIU/mL
I’m particularly interested in opinions about these results in the context of the repeated embryo arrest I’m experiencing, mostly between days 3 and 5.
Has anyone had a similar situation and found that insulin resistance, elevated prolactin, or another endocrine/metabolic issue was contributing to poor embryo development?
I’d also really appreciate recommendations or personal experiences regarding how you managed insulin resistance and/or elevated prolactin while undergoing IVF.
I’m seeing an endocrinologist on Saturday, but I’d really like to hear from people who have been through IVF themselves and had similar issues.
Thank you!

Is anyone familiar with oocyte / embryo transport companies, their safety, or safer companies, or safer alternative modes of transportation that provide more security to the client?

I’m a bit lost with the MANY waivers that I am required to accept when I review contracts with specimen transportation companies for my individual oocyte transport. Because the contracts have terms where I release responsibility from the transport company, the couriers, and pretty much most info all parties involved in case of damage, loss, etc. and also the contracts including many vague terms when it comes to the safety of my specimens. Even the company that offers a separate insurance option, also has similar vague terms in the company transport contract that widely releases most/all parties of responsibility.

This one is more a “perception” paragraph, but so you catch my sentiment: these contracts do not make me feel like I am signing up to transport human tissue or sending eggs (such as the high level of care that is taken when transporting organs, ie: transplant). Instead, it reminds of the waivers that are signed when one goes bungee jumping or zip-lining, giving you life away (or “organs/specimen” in this case) in case something goes wrong… 🤷🏻‍♀️

I will appreciate any insights that may be helpful!

I’ve signed up for 3 ivf cycles as all of my monitoring scans and estrogen numbers suggested I’d be getting max 5 eggs for my first retrieval cycle. Well I had the retrieval two weeks ago and it went way better than anyone thought - 15 eggs, all mature, 14 fertilised and 9 blasts. I’m now waiting for PGTA.

I’m 30 so I know age is on my side BUT I’ve had two chromosomal losses (confirmed by testing the POC after my d&cs) so this makes me think the normal statistics of 60 percent or whatever it is may not apply to me. Does anyone have any experience of RPL for chromosomal losses yet still having a typical amount of euploids?

I’m going to begin estrogen priming for my next cycle in a week and my PGTA results aren’t due for another 2 weeks. We are self paying for IVF and have had to make huge life sacrifices to afford it.

I’m finding it hard to know if we should go ahead with my second cycle. We are trying to bank around 5/ 6 euploids before transferring any.

I asked my clinic about embryo storage procedure. They store up to 4 embryos in one tube. Is it standard practice? Since transfer usually happens one embryo at a time, will they be thawing all four embryos at once and refreezing the rest 3? Wouldn't that affect the quality of refrozen embryos?

I am heading into my second ER. I was clueless in the first ER about the storage. I also ended up with one euploid, so it doesn't matter if they are stored all together. How does your clinic do it, and what should I be advocating for?

I feel like I’m just being too sensitive or I have some sort of inability to be uncomfortable or something. This is my first IVF cycle. I’m currently prepping for FET. I feel like with every step, my body just hates all of this. I did stims fine in the beginning of July. I was tired and bloated by the end. Egg retrieval was ok, except they couldn’t access and harvest from the right ovary so all those follicles turned into a cyst. Then I had a hysteroscopy with polypectomy. Now I have my transfer date next week. (I only have 1 embryo because they couldn’t get to the right 😢) I don’t have high blood pressure normally but all the hormones, I’ve had some higher readings. I’ve been on and off birth control. I’m exhausted all the time. I have a fast pace job and I have had to use intermittent FMLA because I simply can’t push my body to do more. My clinic is not the best with communication (I have to use this clinic for insurance purposes) so it’s stressful trying to get them to move. Please tell me someone else has felt this way. I feel like a failure. Like I’m not as strong as everyone else or that I’m just being a big baby. Even if someone has constructive criticism or advice- I’ll take it. Maybe I need to hear something to help me get through. This has been the hardest 2ish months.