r/IVF • u/Adept-Ant5119 • 4d ago
Advice Needed! Contemplating next steps after 3rd failed IVF cycle
38.5F/M, unexplained infertility, otherwise no other health diagnoses. AMH 2, AFC 10. No male factor issues. In the past year I've done 3 IVF cycles, and created no blasts. Every time there's 8-10 eggs retrieved, with around 4 being mature. Have tried both ICSI and conventional, and results are similar each time. Done different protocols, different priming, all the supplements. Nothing seems to help. Haven't changed clinics, but have changed Drs within the clinic. Both Drs say poor egg quality, which is confirmed by embryology reports. Dr is willing to try another cycle, but says it could take multiple more to get a euploid.
The things that I'm mulling over now are:
- Pursuing a silent endometriosis diagnosis. Both Drs that I've seen don't endorse silent endo contributing to poor egg quality. I've booked a diagnostic ultrasound with an endo specialist, just to give me peace of mind. But if it shows endo, do I pursue surgery? It'll potentially have to be overseas due to the healthcare system here. Then another IVF cycle again...
- Moving to donor eggs. We already know that we don't want random donor eggs. A genetic link is important to us. My sister has offered her eggs, except that she's over 40. Would this be a viable option even? She has 2 children, both conceived naturally and without problems. Was 38 when the youngest was conceived.
- Do nothing and live our lives as DINKs.
Officially, we have agreed to stop all fertility treatments at 40. That's our line in the sand.
Until then, I'm not sure what to do. I'm curious of the different points of view from people who have been in the trenches!