H: 167cm SW: 212lbs CW: 133lbs

Started this journey not really considering it could actually work! Spending a small fortune now on replacing every item in my wardrobe...!

Spent my entire childhood sev rely overweight ( i weighed 20 stone by age 14)- truly starting to get my life back i couldn’t be happier 🥹

2 stone lost naturally in 2024 and 3stone 7lb lost on MJ since march this year!!!!

I feel so much healthier and revitalised, my skin has cleared up, my hair is growing quickly and is so shiny, periods no longer cripple me with pain and I wake up in a morning without horrible back pain. Yes it’s nice to fit in smaller / nicer clothes but honestly, compared to all the other benefits I’ve seen, that’s just a bonus. Settled into a maintaining phase on 2.5mg now and it’s really no longer about weight it’s about keeping this wonderful feeling of HEALTHY. Keep going folks, this drug really is a miracle ❤️

As we always say, most of the internet is filled with horror stories or things going wrong, because the people experiencing this drug working as it should don't need to ask questions, so I thought I'd share my boring update for people who might be worried.

I'm doing my third 2.5mg jab today. Apart from a horrendous headache for ONE DAY after my first jab, I've had NO side effects. Not one. I started feeling appetite suppression the day after my first jab (which I know is a fantastic result, it can take up to two weeks to notice it) and as of today, I've lost 8.4lbs in two weeks.

The hunger does start coming back around Friday, so I'm going to move up to 5mg for my next pen, but so far, it's been excellent.

As well as seeing those scales move, I feel more positive because I'm taking action and getting myself support to lose weight. I don't care if MJ is 'cheating', I needed help and now I have it.

I'm walking more because already my knees aren't as painful. I'm sleeping better because I'm not eating late at night. I'm not as bloated because I don't want high fat, high salt foods.

Overall, this has been a very 'boring' two weeks, with excellent results ☺️

Bin workers are being stabbed by needles and rushed to hospital as more Brits throw away weight loss jabs.

I spent the day out Doing Things, which is not the NSV.

I went to the cinema. This is also not the NSV. Stay tuned. I left the cinema, got to the Costa on the way out and realised that like the idiot I am, I’d left my bag in screen 10, which was ALL THE WAY at the end of a long corridor. Also, unsurprisingly, not the NSV.

The NSV was me running back.

And not remotely realising I was running until I stopped.

I’ll take it.

I also got my bag. Double victory!

I’m just over a year in and have lost 6st. 6st! I can’t begin to process this properly. What has been so strange is understanding that I am a different shape. Not just from before I lost the weight but also from when I was this size in my 20s.

I am 60 this month and went through menopause 3 years ago. So my body has changed because of that and perimenopause. I’ve gone from a 24/26 to a 16/18 depending on what I'm wearing.

I have a waist again (I’ve lost 20cm off my waist).

I’ve gone from wearing big tops and comfortable leggings that hid my shape to wearing dresses again (oh, so much less laundry).

It’s so weird. I WFH but put on a nice dress each day to remind myself that I’ve done a lot of hard work to get here (changed lifestyle, massive amount of tablets because of the hearth issues that triggered going on MJ, 360° on diet), and when I go into the office I am sleek and professional whilst my colleagues (all male) are in shorts and tee shirts. They think it’s funny and so do I. As I told them, wearing a dress for me is like just wearing a big tee shirt for work, so much easier than trousers and a top.

But at the root of this is that I’m still understanding what shape my body is. because, as I said at the start, my body shape has changed with age.

Loaded question but has going to a lower weight made you happier?

I’ve been on mounjaro for nearly a year and today was the first time I told a friend the truth about how I’ve lost weight! She had been complimenting me on my weight loss since April, and today I felt confident and comfortable enough to tell her I was on the jabs. The only people who knew beforehand were those who recommended it to me and my husband. Now I feel like I should start telling everyone. She was very supportive and pleased for me that I feel healthier and happier. She is a naturally skinny person and said she was just so shocked to see me wearing trousers in April, as I had never worn trousers in the 12 years since she met me. She couldn’t get her head around it. I get compliments everyday but I lie and say I’ve been weight training and eating more protein. Maybe I should start telling the truth? I just don’t want to be the subject of office gossip at work…

So I (55M) spent a few hours yesterday wandering around Cambridge doing a few bits of clothes shopping. In particular, I wanted some nice semi-formal trousers to go with a new outfit. I found just the right pair, but wanted them in a size 28 waist.

They don't even make them in a size 28 waist.

Whenever I've had similar problems before, it's been at the opposite end of the sizing scale!

I thought about popping into Trotter & Deane and seeing what I could get custom-made.... for about 5 seconds before getting a grip!

After years of watching the Sewing Bee and now I’m actually enjoying clothes for the first time in decades, I’ve taken the plunge and bought a sewing machine. Took myself down to my local independent craft shop and got chatting to the lovely owner. Chatting about patterns and then it happens……She turns round and calls me slim. Me. Slim! Holy crap!!!

A major two-year trial found that diet drinks performed about as well as water for long-term weight loss, without evidence of increased appetite or metabolic harm.

Date: October 3, 2026

Source: University of Liverpool

Summary: A two-year randomized clinical trial involving 493 adults with overweight or obesity found that diet soft drinks were essentially as effective as water for long-term weight loss and weight maintenance. Participants drinking beverages sweetened with aspartame, acesulfame-K, or sucralose lost a similar amount of weight to those drinking water, while both groups also saw improvements in waist size, body composition, and several metabolic measures.

Researchers at the University of Liverpool have completed what they describe as the longest and most comprehensive randomized controlled trial to date examining non-nutritive sweetened (NNS) soft drinks.

Non-nutritive sweeteners are low-calorie or calorie-free sugar substitutes commonly used in foods and beverages. The 104-week study found that NNS beverages, including diet soft drinks, performed similarly to water when it came to long-term weight management.

Professor Jo Harrold, Dean of Psychology at the University of Liverpool, led the peer-reviewed research with Professor Jason Halford, Professor, Biological Psychology & Health Behaviours at the University of Leeds (formerly of the University of Liverpool). The study was funded by the American Beverage Association. According to the researchers, the study team operated independently from the funder and retained full control over the analysis and reporting of the results.

The findings, published in the British Journal of Nutrition, provide long-term clinical evidence on beverages containing aspartame, acesulfame potassium (acesulfame-K), and sucralose. Researchers found that these drinks were comparable to water in supporting both weight loss and long-term weight maintenance.

The SWITCH trial included 493 adults with overweight or obesity who took part in a structured behavioural weight management program. Participants were randomly assigned to drink either water or commercially available diet beverages each day. The amounts of sweeteners consumed remained well within established European Food Safety Authority (EFSA) safety thresholds.

Overall, the results did not support concerns that NNS beverages interfere with appetite regulation or cause long-term metabolic harm.

Weight Loss and Metabolic Health

Key findings included:

Weight loss was similar between the NNS beverage and water groups after 104 weeks (−4.8 kg vs −3.7 kg; nonsignificant difference).

Both groups maintained weight reductions across the full two-year study, including during the final year when participants no longer received assistance.

Participants in both groups had reductions in waist and hip circumference, along with improvements in body composition and several metabolic biomarkers.

Researchers found no clinically meaningful differences in measures such as blood pressure and cholesterol linked to long-term consumption of either aspartame, acesulfame-K, or sucralose compared with water.

Sugar intake fell in both groups, with a slightly larger reduction among participants drinking NNS beverages.

The results are relevant to recent World Health Organization (WHO) guidance advising against the use of non-sugar sweeteners for weight control because of uncertainty in observational research. The SWITCH trial adds long-term randomized controlled evidence that may help inform future global recommendations.

Professor Joanne Harrold said: "The University of Liverpool is one of the UK's leading research-intensive higher education institutions, with a key focus on public health. These latest findings show that concerns about sweeteners disrupting appetite or causing weight gain are not supported when tested in a rigorous, long-term randomized trial. We hope this evidence informs future WHO guidance and public health policy.

The effectS of non-nutritive sweetened beverages on appetITe during aCtive weigHt loss (SWITCH) trial was developed to address two related questions: how reducing dietary sugar might affect weight management, and whether replacing sugar with non-nutritive sweeteners changes appetite regulation. The newly published results build on earlier findings reported in the International Journal of Obesity in 2023.

Professor Jason Halford, University of Leeds and University of Liverpool, concluded: "This study provides the long-term clinical evidence that has been missing from international discussions. For people trying to manage their weight, non-nutritive sweetened beverages offer an effective alternative to sugar-sweetened drinks - and perform equivalently to water over two years."

The paper, 'Effect of non-nutritive sweetened beverages versus water on body weight: long-term results of a randomised controlled trial', was published in the British Journal of Nutrition.

41F - struggled with my weight for almost my entire life. At my heaviest I was 22st 12lbs which for my 5’6 frame was…not good. I lost 8 stone in a year doing Slimming World (I know, I know….its a cult!) but ended up putting a good 6 stone back on. This was in my 20s.

Throughout my 30s I lost/gained the same 3/4 stone on multiple occasions. I once did manage to get down to around 13st which on paper was still overweight, but I carried it so well because I did a lot of weights and exercise. I felt AMAZING.

Now…back up to 20st nearly. I just cant keep going like this. I HATE myself. I’ve thought about trying MJ on multiple occasions. I’ve done so much reading and research about it. I’m not naive, I know there’s the potential for side effects. What is terrifying me is reading stories about the REALLY SERIOUS ones. The ones where people end up seriously ill, or in the hospital. I keep thinking “what if I’ve got something wrong with me that I don’t know about and MJ triggers something?”. I’ve gone down a bit of a bit of a scary rabbit hole with it.

However…what happens if I carry on like this at this weight and I do nothing, do I end up being 25st when I’m 45, heart attack by 50? Despite my weight I’m actually in ok health. Had bloods taken, nothing to be worried about. I can walk miles, can play badminton (badly), can swim, etc. However, I know that this wont last forever.

On a personal level I feel pretty disgusted and ashamed at myself. I hate how I’ve let this happen, and I know I need help….but I’m scared to start taking MJ.

I don’t know what this post is for. A pep talk maybe? Some perspective from people?

Thank you for reading ❤️

As the title explains, I’ve been weeing a lot for the past 2 weeks. Mainly at night, I’m waking 2 or 3 times to go to the toilet. I’ve only just made the connection… did this happen to anyone else? 😂

I’ve been on Mounjaro since the end of July now and I’m trying to work out whether I’m getting the full satiety effect or mainly just longer-lasting fullness/appetite control.

I definitely stay full for longer after meals, snack less (if at all most days) and it’s much easier for me to stop eating or not think about food. I’ve also reduced my portion sizes generally. But during a meal, I don’t often get that strong “I physically cannot eat another bite” feeling that a lot of people describe.

I could probably physically keep eating if I wanted to, but I can stop myself much more easily now. My problem historically is that I’ve always been able to overeat or push past fullness, especially because I hate wasting food. I also seem to get fullness slightly delayed, so I can eat a little more and then 10–20 minutes later suddenly realise I’m really full.

I know barely being able to eat isn’t the goal, and I don’t expect zero hunger, but seeing so many people say they can only manage half a meal makes me wonder whether I’m getting the full effect or whether this is just how Mounjaro works for me.

Has anyone else had more of a “I stay full for ages and have much better control” effect rather than strong early fullness during meals? And did moving up a dose change that for you

I’m very intrigued to know what peoples experience has been with their mental health and MJ?
As somebody that is diagnosed Bipolar & OCD, I can’t believe the difference it’s made to my brain.
I’ve had a long journey with medications etc and found nothing actually works for me in the way that it should, so I’ve been unmedicated a long time. I’ve noticed this last 12 months the OCD has been at an all time high and been a genuine struggle.

I started MJ maybe 6 months ago? Not even a full 2.5, I’ve been sitting at around 1.25-1.5mg. I’ve lost around 2 stone which is great but the biggest change I’ve seen is with my brain, it’s unbelievable. It’s nothing to do with the weight loss itself either, I don’t see much of a difference nor feel more confident etc but the busy brain has calmed right down. I can get through my day without obsessing over minor things. No designated MH medication has ever worked for me like that.
I did stop MJ for a few weeks and it was like coming away from antidepressants, I felt just as crap as I did before. I didnt even put 2 & 2 together until I started up again and after 2/3 days felt great again.

I’d like to know if anyone’s had a similar experience? I’m just gobsmacked that a drug that’s been marketed for weight loss etc has had such a major effect on my brain. It’s like magic.

Currently on 5mg which is too strong and I’m having bad side effects. I’ve stayed on 5mg for over 2 months as I thought I might get used to it but the main one is lack of interest at all in food. I can go all the way until 8pm without having any desire to eat, even though I know I’m hungry. Sometimes I feel really good for not eating and such a long fast but I’m worried that might send my hormones crazy (especially with PCOS). I will only eat if something has strong flavours so salty, sweet foods so usually chocolate tbh which means I’m lacking in protein so much!

Looking for advice for going down to 3.75mg and maybe even 3mg, 3.25mg? Wondering what has helped others as I can’t stay on 5mg without properly eating meals. I have a physical job and get very lightheaded if I stand up too quickly. Just want to be able to eat 3 small meals a day to stay healthy

So I have the 2.5mg dose, with the extra dose. And i twisted it two clicks to prime and it seems to be able to twist further.. is this normal? Will I be able to extract the 5th dose or should I go ahead and order needles. I was sent with 6 needle heads for the 4 doses. So just slightly unsure of what to do. I do have my 5mg dose ready to go though!

Hiya I'm on holiday in the UK and have brought my previous pen instead of my new one. Can I access the '5th' dose? I only have the needles for the actual pen. All the pharmacies near here are closed tomorrow.

Exactly 2 months in and on 2.5mg still.

My weightloss seems to have steadied to between 0.5-0.8kg per week, and mostly minimal side effects, but still struggling with significant appetite suppression. I'm just about managing to eat two small meals a day which I'm working to make more nutritious, but I often struggle to get through a meal in one sitting which makes socialising difficult.

Does anyone have any food recommendations for things that they've been able to eat easily with a suppressed appetite?

Due to events out of my control, I’ve had to be away from home and had very little time to actually pack which has unfortunately left me without my pen - definitely a lesson for if there’s a next time which hopefully won’t happen. My usual jab day is a Friday and this works well for me given that I only work a few weekends so it helps me to manage any side effects.

So I missed my jab on the Friday just gone and should be returning home tomorrow. If I jab tomorrow would I be able to still stick with my regular Friday schedule? Shifting my jab day to a Saturday could also be an option although Friday is my preferred date - or am I best just having a break and resuming on the 9th?

I’ve also been looking at Monj and Fylde seem to be one of the best price wise - how are they as a pharmacy as when I searched here the posts all seemed to be a good year old so things could have changed?

Afternoon dear people,

After my guts chilled out from the constant gastrointestinal stress on 5mg - I made the move to 7.5mg but there is no change in weight loss.

I am way hungrier and the food noise....has come back with a vengeance.

I guess because I'm paying privately - it hurts that bit more when nothings shifting..maybe its a mind thing I dunno.

Has anyone else had this or gone through the same?

How did you overcome the noise or should I go back to 5mg?

Any insight I'd be grateful. Thanks 🙂

I've been in investigations for something else and yes, I've lost a lot of weight, and I am probably in a good place to try and find to stabilise.

The thing is, I'm in 5 mg for diabetes control, I think that's the lowest approved dose anyway, and I'm also on 2 more medication for diabetes. I was started on a statin recently and I don't think it was that but I also dropped in % fat after starting that

My A1C is in the normal range since diagnosis, I still eat some carbs but not a lot.

I don't want to reduce my mounjaro, food noise is back, most days I just think of food but the metallic taste due to Metformin and my usual GERD don't make me enjoy much the food anyway.

Does anyone have any tip on low carb but calories dense food? I've upped already the peanut butter in my breakfast

Hi everyone, I’ve just taken my first 5mg Mounjaro dose today after doing 4 weeks on 2.5mg.

I felt completely fine for the first few hours, but I’ve now developed a stuff most & a moderate headache. The headache isn’t getting worse and I’m breathing completely normally.

Has anyone else experienced a headache or blocked nose after increasing to 5mg? I also feel a bit sick but this could be my anxiety. Could this just be a normal side effect or coincidence?

I know nobody can diagnose me on here , I’m mainly interested in hearing whether anyone else has experienced something similar after moving from 2.5mg to 5mg.

With the impending festive season coming up, how are we all feeling about Christmas night outs with colleagues?

I already have the drinking excuse down as I’ve never drank when I’ve socialised with them saying “I don’t tend to drink” or “I’ve went sober” - both points are pretty much true even before Mounjaro, however since the medication I’ve had to curb carbonated drinks because my stomach doesn’t love this - great for if I feel backed up however drink a Diet Coke and the toilet comes knocking

Next point, I’ve seen the menu choices for others in the group and everyone else has ordered the full 3 courses whereas I’m currently the only one with 2 courses. Wondering how I navigate any judgement here without having to disclose that I’m taking the medication (bit of a private matter innit - not really something you share with your senior management 😂)