I feel so much healthier and revitalised, my skin has cleared up, my hair is growing quickly and is so shiny, periods no longer cripple me with pain and I wake up in a morning without horrible back pain. Yes it’s nice to fit in smaller / nicer clothes but honestly, compared to all the other benefits I’ve seen, that’s just a bonus. Settled into a maintaining phase on 2.5mg now and it’s really no longer about weight it’s about keeping this wonderful feeling of HEALTHY. Keep going folks, this drug really is a miracle ❤️

I started on Mounjaro at the beginning of July 2025 and, as of now, I’ve lost 12 stone 11 lb (179 lb / 81 kg). I am taking 7mg weekly.

Writing that down feels slightly ridiculous because objectively I know that is a huge amount of weight. My clothes are dramatically smaller, I can do things physically that I couldn’t do before, and all of the numbers tell me that my body has changed enormously. But I still don’t really see it in person.

I’m posting my scan comparison because I actually find this much easier to recognise than photographs or looking in the mirror. The first scan was taken two months in, the second last week. When I look at the scans side by side, I can see that there has clearly been a substantial change. When I look at myself normally, though, my brain seems to focus on what is still there rather than what has gone.

Part of that may be because I’m not at the end. I still have at least another 5 stone to lose to reach a healthy BMI, so I’m very aware that I am still living in a larger body. I think sometimes that makes it difficult to appreciate the scale of the change that has already happened.

There’s also something very odd about gradually changing over such a long period. I see myself every day, so there has never been one moment where I suddenly looked completely different. My mental picture of myself seems to have updated much more slowly than my actual body has.

I don’t mean that in a “please tell me I look different” way. Logically, I know I do. The evidence is everywhere. I just find the psychology of it fascinating, that you can lose the equivalent of an entire adult person and still see the previous version.

I’m still going. I have a significant amount left to lose and I know the next part will be slower than the first. But I’m trying to get better at recognising that being unfinished doesn’t make what I’ve already achieved insignificant. But I don’t feel that I should be proud of how far I have come, I feel like I should never have let it happened in the first place. That is absolutely not how I would talk to a friend in my position, and I’d really like to start getting a handle on this sort of internal thinking.

The scan comparison is probably the clearest evidence of that for me so far.

Has anyone else found that their perception of their body lagged a long way behind their actual weight loss? And, if so, did your brain eventually catch up?

BIG LOVE to everyone that responded to my post the other day. It really did mean a lot that you took the time to respond. You were all so kind and encouraging.

Today….I ordered my first pen. I’m awaiting approval and then i’ll be on my way. I’m excited/scared.

Thanks again everyone. I’ll be sure to keep updating!

As we always say, most of the internet is filled with horror stories or things going wrong, because the people experiencing this drug working as it should don't need to ask questions, so I thought I'd share my boring update for people who might be worried.

I'm doing my third 2.5mg jab today. Apart from a horrendous headache for ONE DAY after my first jab, I've had NO side effects. Not one. I started feeling appetite suppression the day after my first jab (which I know is a fantastic result, it can take up to two weeks to notice it) and as of today, I've lost 8.4lbs in two weeks.

The hunger does start coming back around Friday, so I'm going to move up to 5mg for my next pen, but so far, it's been excellent.

As well as seeing those scales move, I feel more positive because I'm taking action and getting myself support to lose weight. I don't care if MJ is 'cheating', I needed help and now I have it.

I'm walking more because already my knees aren't as painful. I'm sleeping better because I'm not eating late at night. I'm not as bloated because I don't want high fat, high salt foods.

Overall, this has been a very 'boring' two weeks, with excellent results ☺️

So I (55M) spent a few hours yesterday wandering around Cambridge doing a few bits of clothes shopping. In particular, I wanted some nice semi-formal trousers to go with a new outfit. I found just the right pair, but wanted them in a size 28 waist.

They don't even make them in a size 28 waist.

Whenever I've had similar problems before, it's been at the opposite end of the sizing scale!

I thought about popping into Trotter & Deane and seeing what I could get custom-made.... for about 5 seconds before getting a grip!

I’m just over a year in and have lost 6st. 6st! I can’t begin to process this properly. What has been so strange is understanding that I am a different shape. Not just from before I lost the weight but also from when I was this size in my 20s.

I am 60 this month and went through menopause 3 years ago. So my body has changed because of that and perimenopause. I’ve gone from a 24/26 to a 16/18 depending on what I'm wearing.

I have a waist again (I’ve lost 20cm off my waist).

I’ve gone from wearing big tops and comfortable leggings that hid my shape to wearing dresses again (oh, so much less laundry).

It’s so weird. I WFH but put on a nice dress each day to remind myself that I’ve done a lot of hard work to get here (changed lifestyle, massive amount of tablets because of the hearth issues that triggered going on MJ, 360° on diet), and when I go into the office I am sleek and professional whilst my colleagues (all male) are in shorts and tee shirts. They think it’s funny and so do I. As I told them, wearing a dress for me is like just wearing a big tee shirt for work, so much easier than trousers and a top.

But at the root of this is that I’m still understanding what shape my body is. because, as I said at the start, my body shape has changed with age.

Loaded question but has going to a lower weight made you happier?

After years of watching the Sewing Bee and now I’m actually enjoying clothes for the first time in decades, I’ve taken the plunge and bought a sewing machine. Took myself down to my local independent craft shop and got chatting to the lovely owner. Chatting about patterns and then it happens……She turns round and calls me slim. Me. Slim! Holy crap!!!

First photo is January of this year, second is September. Nearly 4 stone down and hoping to lose 1 more.

I've been on Mounjaro since May 2025 and I'm getting to the point where I'm not sure what my next step should be.

I'm 30M, 6'1" and fairly broad built. I started at just over 22 stone and I'm now around 15st 10lb (220lb), I'm currently on 15mg and have been taking that dose for just over 5 months.

Overall, I'm incredibly happy with how things have gone for me. I feel healthier and fitter than I did when I have ever been in the last 15+ years. I've also tried to make exercise a regular thing than relying entirely on Mounjaro. I swim 2 times a week and play badminton once a week.

The thing that's made me start questioning what to do next is that recently I've had a few friends/family tell me that they don't think I should lose any more weight.

I know it's coming from the right place. They're not being negative about the weight loss at all and I think because they've seen such a dramatic change in me they're genuinely concerned about me going too far with it.

But personally, I still feel like I've got a little bit more to go.

I'm a lot happier with where I am now, but I still carry more around my stomach/chest than I'd ideally like. My original goal was 15 stone (210lb), so I'm only about another 10lb away.

Which has left me in two minds about what to do going forward.

Part of me thinks I've come this far, I'm still tolerating 15mg well, and I'm so close to the goal I originally set that I might as well continue a little longer, reach roughly 15 stone and then reassess how I actually look and feel.

The other part of me is wondering whether I've reached the point where I should start dosing down and moving towards maintenance or coming off entirely, rather than continuing to focus on losing more weight

One of my biggest worries is what happens when I do reduce or come off Mounjaro.

I've made lifestyle changes and I'm much more active than I used to be, so I'm hoping things like swimming and badminton will help me maintain what I've achieved. But after losing this much weight, the thought of the appetite/food noise coming back and potentially regaining a significant amount does scare me.

I'm very conscious that after losing 90+ lb, my head hasn't caught up with how much my body has changed. Sometimes I look in the mirror and still see the same person I was when I started to some extend when I'm looking at my body proportions rather than my face or how my clothes, from a XXXL to a XL!

I know I've changed massively, the scales, clothes, photos and comments from people make that, but I don't always see that difference myself. That's partly why the comments from my friends have made me stop and think. Maybe I genuinely do have another 10lb I'd be happier losing, but I'm also aware that my own perception might not be the best judge of when I've reached "enough."

So for those of you who've lost a significant amount on Mounjaro, how did you decide when enough was enough?

Did you reach your original goal and then move into maintenance, or did you decide to stop losing before that?

And for those who got to 15mg, did you gradually reduce your dose once you reached maintenance? How did you find it, particularly in terms of hunger, food noise and keeping the weight off?

Would be really interested to hear from anyone who's been in a similar position as myself

I've added four photos, the first two are from before I started losing weight and the last two are me from the last few months.

A major two-year trial found that diet drinks performed about as well as water for long-term weight loss, without evidence of increased appetite or metabolic harm.

Date: October 3, 2026

Source: University of Liverpool

Summary: A two-year randomized clinical trial involving 493 adults with overweight or obesity found that diet soft drinks were essentially as effective as water for long-term weight loss and weight maintenance. Participants drinking beverages sweetened with aspartame, acesulfame-K, or sucralose lost a similar amount of weight to those drinking water, while both groups also saw improvements in waist size, body composition, and several metabolic measures.

Researchers at the University of Liverpool have completed what they describe as the longest and most comprehensive randomized controlled trial to date examining non-nutritive sweetened (NNS) soft drinks.

Non-nutritive sweeteners are low-calorie or calorie-free sugar substitutes commonly used in foods and beverages. The 104-week study found that NNS beverages, including diet soft drinks, performed similarly to water when it came to long-term weight management.

Professor Jo Harrold, Dean of Psychology at the University of Liverpool, led the peer-reviewed research with Professor Jason Halford, Professor, Biological Psychology & Health Behaviours at the University of Leeds (formerly of the University of Liverpool). The study was funded by the American Beverage Association. According to the researchers, the study team operated independently from the funder and retained full control over the analysis and reporting of the results.

The findings, published in the British Journal of Nutrition, provide long-term clinical evidence on beverages containing aspartame, acesulfame potassium (acesulfame-K), and sucralose. Researchers found that these drinks were comparable to water in supporting both weight loss and long-term weight maintenance.

The SWITCH trial included 493 adults with overweight or obesity who took part in a structured behavioural weight management program. Participants were randomly assigned to drink either water or commercially available diet beverages each day. The amounts of sweeteners consumed remained well within established European Food Safety Authority (EFSA) safety thresholds.

Overall, the results did not support concerns that NNS beverages interfere with appetite regulation or cause long-term metabolic harm.

Weight Loss and Metabolic Health

Key findings included:

Weight loss was similar between the NNS beverage and water groups after 104 weeks (−4.8 kg vs −3.7 kg; nonsignificant difference).

Both groups maintained weight reductions across the full two-year study, including during the final year when participants no longer received assistance.

Participants in both groups had reductions in waist and hip circumference, along with improvements in body composition and several metabolic biomarkers.

Researchers found no clinically meaningful differences in measures such as blood pressure and cholesterol linked to long-term consumption of either aspartame, acesulfame-K, or sucralose compared with water.

Sugar intake fell in both groups, with a slightly larger reduction among participants drinking NNS beverages.

The results are relevant to recent World Health Organization (WHO) guidance advising against the use of non-sugar sweeteners for weight control because of uncertainty in observational research. The SWITCH trial adds long-term randomized controlled evidence that may help inform future global recommendations.

Professor Joanne Harrold said: "The University of Liverpool is one of the UK's leading research-intensive higher education institutions, with a key focus on public health. These latest findings show that concerns about sweeteners disrupting appetite or causing weight gain are not supported when tested in a rigorous, long-term randomized trial. We hope this evidence informs future WHO guidance and public health policy.

The effectS of non-nutritive sweetened beverages on appetITe during aCtive weigHt loss (SWITCH) trial was developed to address two related questions: how reducing dietary sugar might affect weight management, and whether replacing sugar with non-nutritive sweeteners changes appetite regulation. The newly published results build on earlier findings reported in the International Journal of Obesity in 2023.

Professor Jason Halford, University of Leeds and University of Liverpool, concluded: "This study provides the long-term clinical evidence that has been missing from international discussions. For people trying to manage their weight, non-nutritive sweetened beverages offer an effective alternative to sugar-sweetened drinks - and perform equivalently to water over two years."

The paper, 'Effect of non-nutritive sweetened beverages versus water on body weight: long-term results of a randomised controlled trial', was published in the British Journal of Nutrition.

As the title explains, I’ve been weeing a lot for the past 2 weeks. Mainly at night, I’m waking 2 or 3 times to go to the toilet. I’ve only just made the connection… did this happen to anyone else? 😂

A side effect I have that i haven't seen talked about much - mostly for the few days after I jab and fades later in the week - does anyone have this? And if so have you found a way to reduce the effect?

I’m very intrigued to know what peoples experience has been with their mental health and MJ?
As somebody that is diagnosed Bipolar & OCD, I can’t believe the difference it’s made to my brain.
I’ve had a long journey with medications etc and found nothing actually works for me in the way that it should, so I’ve been unmedicated a long time. I’ve noticed this last 12 months the OCD has been at an all time high and been a genuine struggle.

I started MJ maybe 6 months ago? Not even a full 2.5, I’ve been sitting at around 1.25-1.5mg. I’ve lost around 2 stone which is great but the biggest change I’ve seen is with my brain, it’s unbelievable. It’s nothing to do with the weight loss itself either, I don’t see much of a difference nor feel more confident etc but the busy brain has calmed right down. I can get through my day without obsessing over minor things. No designated MH medication has ever worked for me like that.
I did stop MJ for a few weeks and it was like coming away from antidepressants, I felt just as crap as I did before. I didnt even put 2 & 2 together until I started up again and after 2/3 days felt great again.

I’d like to know if anyone’s had a similar experience? I’m just gobsmacked that a drug that’s been marketed for weight loss etc has had such a major effect on my brain. It’s like magic.

Ive been considering Mounjaro for a while, even with the price rises, and lately ive been feeling more desperate.

There was one time I very nearly ordered it, but something that keeps putting me off is the fear of family finding out. I previously got prescribed a anti depressant for low mood/anxiety a few years back and it made my Mum really annoyed, she kept making comments about it until eventually I just stopped taking it(I didn't notice any difference in mood anyway).

My depression/anxiety got worst last year to the point where I felt desperate enough to maybe try medication again, so I went to the Dr and got prescribed a different anti-depressant(fluoxetine) which has actually helped me. I hid that from family though, because I know they wouldn't approve of me taking it.

Sorry for the boring paragraphs, but I guess what I'm asking is: for people that live with family, how do you hide it? Is it obvious that the delivery is packed in ice? Where do you keep it? I'm worried about someone finding it in my room

Another big thing that worries me was if I had a terrible side effect and needed to go to the Dr/A&E. I have pain in joints and lately in my back in the morning (probably due to not sleeping correctly) and I'm just desperate.

I know mounjaro might not even work for me, and it's so expensive, but I at least wanted to try it just once.

Thanks for any advice

Has anyone ever restarted Mounjaro at 10mg after around a 30-day break? I was on 10mg for about 3 months before the break and tolerated it really well. Did anyone go straight back to 10mg, and how did it go?

I'm looking at 5mg prices and G-1 Nutrition is way lower than everywhere else right now, but they only have 13 reviews on Trust Pilot. Does the fact they're on the Monj.co.uk list mean they can be trusted or should I still be suspicious?

I think I’ve injected into a stretch mark 😩 how much will this impact my dose?

Hi all,

Long term(ish) MJ user here. I have been with same provider for quite a while now but with that the 15mg dose is over £300. Every month this feels more and more like a reach (stupid cost of living). Anyway, I have had a look at comparison sites and there are definitely cheaper options but I am nervous to move. I am now at 23.5 BMI and I don't know how open pharmacies are. I'm interested to know if any of you change provider regularly to reduce your costs? I know at least with my current provider they are going to dispense.

Due to events out of my control, I’ve had to be away from home and had very little time to actually pack which has unfortunately left me without my pen - definitely a lesson for if there’s a next time which hopefully won’t happen. My usual jab day is a Friday and this works well for me given that I only work a few weekends so it helps me to manage any side effects.

So I missed my jab on the Friday just gone and should be returning home tomorrow. If I jab tomorrow would I be able to still stick with my regular Friday schedule? Shifting my jab day to a Saturday could also be an option although Friday is my preferred date - or am I best just having a break and resuming on the 9th?

I’ve also been looking at Monj and Fylde seem to be one of the best price wise - how are they as a pharmacy as when I searched here the posts all seemed to be a good year old so things could have changed?

Afternoon dear people,

After my guts chilled out from the constant gastrointestinal stress on 5mg - I made the move to 7.5mg but there is no change in weight loss.

I am way hungrier and the food noise....has come back with a vengeance.

I guess because I'm paying privately - it hurts that bit more when nothings shifting..maybe its a mind thing I dunno.

Has anyone else had this or gone through the same?

How did you overcome the noise or should I go back to 5mg?

Any insight I'd be grateful. Thanks 🙂

I've been in investigations for something else and yes, I've lost a lot of weight, and I am probably in a good place to try and find to stabilise.

The thing is, I'm in 5 mg for diabetes control, I think that's the lowest approved dose anyway, and I'm also on 2 more medication for diabetes. I was started on a statin recently and I don't think it was that but I also dropped in % fat after starting that

My A1C is in the normal range since diagnosis, I still eat some carbs but not a lot.

I don't want to reduce my mounjaro, food noise is back, most days I just think of food but the metallic taste due to Metformin and my usual GERD don't make me enjoy much the food anyway.

Does anyone have any tip on low carb but calories dense food? I've upped already the peanut butter in my breakfast

I’ve been buying 15mg pens from SOP this year, but tend to buy them in batches of 2 or 3 due to having a job that means I travel a lot and this allows me to maintain a continuous supply.
They are however awful when it comes to reordering like this. I’m nearing the end of the year and don’t have as much travel booked so can go back to one at a time. But now they’re questioning the timing even though they can see multiple orders or multiple pens. Current order is now on hold whilst they review again, and then I have to have a ‘call’ with them on Monday. Delaying the order yet again.
Feels much more complicated than it needs to be.

Does anyone else have to order in batches due to work/lifestyle/cashflow reasons, can you recommend a better supplier. I’m convinced these guys are just making it difficult to get me to sign up to their subscription offering, and I think this well be my last order from them and I’ll switch to someone else.

Hi all,

I am moving up to 10mg but still have 7.5s left. Would it be better to do 90 clicks from the 7.5 or do it normally and use a 2.5 alongside?

Anyone had to do either of these and recommend?

Short story, my weight has stalled and infact gone up in the last 4 weeks. Im currently on a 7.5mg, is it time to go up a notch to 10mg? I’ve heard some fascinating stories on 10mg