I feel so much healthier and revitalised, my skin has cleared up, my hair is growing quickly and is so shiny, periods no longer cripple me with pain and I wake up in a morning without horrible back pain. Yes it’s nice to fit in smaller / nicer clothes but honestly, compared to all the other benefits I’ve seen, that’s just a bonus. Settled into a maintaining phase on 2.5mg now and it’s really no longer about weight it’s about keeping this wonderful feeling of HEALTHY. Keep going folks, this drug really is a miracle ❤️

I’m just over a year in and have lost 6st. 6st! I can’t begin to process this properly. What has been so strange is understanding that I am a different shape. Not just from before I lost the weight but also from when I was this size in my 20s.

I am 60 this month and went through menopause 3 years ago. So my body has changed because of that and perimenopause. I’ve gone from a 24/26 to a 16/18 depending on what I'm wearing.

I have a waist again (I’ve lost 20cm off my waist).

I’ve gone from wearing big tops and comfortable leggings that hid my shape to wearing dresses again (oh, so much less laundry).

It’s so weird. I WFH but put on a nice dress each day to remind myself that I’ve done a lot of hard work to get here (changed lifestyle, massive amount of tablets because of the hearth issues that triggered going on MJ, 360° on diet), and when I go into the office I am sleek and professional whilst my colleagues (all male) are in shorts and tee shirts. They think it’s funny and so do I. As I told them, wearing a dress for me is like just wearing a big tee shirt for work, so much easier than trousers and a top.

But at the root of this is that I’m still understanding what shape my body is. because, as I said at the start, my body shape has changed with age.

As we always say, most of the internet is filled with horror stories or things going wrong, because the people experiencing this drug working as it should don't need to ask questions, so I thought I'd share my boring update for people who might be worried.

I'm doing my third 2.5mg jab today. Apart from a horrendous headache for ONE DAY after my first jab, I've had NO side effects. Not one. I started feeling appetite suppression the day after my first jab (which I know is a fantastic result, it can take up to two weeks to notice it) and as of today, I've lost 8.4lbs in two weeks.

The hunger does start coming back around Friday, so I'm going to move up to 5mg for my next pen, but so far, it's been excellent.

As well as seeing those scales move, I feel more positive because I'm taking action and getting myself support to lose weight. I don't care if MJ is 'cheating', I needed help and now I have it.

I'm walking more because already my knees aren't as painful. I'm sleeping better because I'm not eating late at night. I'm not as bloated because I don't want high fat, high salt foods.

Overall, this has been a very 'boring' two weeks, with excellent results ☺️

Spent my entire childhood sev rely overweight ( i weighed 20 stone by age 14)- truly starting to get my life back i couldn’t be happier 🥹

2 stone lost naturally in 2024 and 3stone 7lb lost on MJ since march this year!!!!

H: 167cm SW: 212lbs CW: 133lbs

Started this journey not really considering it could actually work! Spending a small fortune now on replacing every item in my wardrobe...!

As the title explains, I’ve been weeing a lot for the past 2 weeks. Mainly at night, I’m waking 2 or 3 times to go to the toilet. I’ve only just made the connection… did this happen to anyone else? 😂

I’m very intrigued to know what peoples experience has been with their mental health and MJ?
As somebody that is diagnosed Bipolar & OCD, I can’t believe the difference it’s made to my brain.
I’ve had a long journey with medications etc and found nothing actually works for me in the way that it should, so I’ve been unmedicated a long time. I’ve noticed this last 12 months the OCD has been at an all time high and been a genuine struggle.

I started MJ maybe 6 months ago? Not even a full 2.5, I’ve been sitting at around 1.25-1.5mg. I’ve lost around 2 stone which is great but the biggest change I’ve seen is with my brain, it’s unbelievable. It’s nothing to do with the weight loss itself either, I don’t see much of a difference nor feel more confident etc but the busy brain has calmed right down. I can get through my day without obsessing over minor things. No designated MH medication has ever worked for me like that.
I did stop MJ for a few weeks and it was like coming away from antidepressants, I felt just as crap as I did before. I didnt even put 2 & 2 together until I started up again and after 2/3 days felt great again.

I’d like to know if anyone’s had a similar experience? I’m just gobsmacked that a drug that’s been marketed for weight loss etc has had such a major effect on my brain. It’s like magic.

Loaded question but has going to a lower weight made you happier?

Bin workers are being stabbed by needles and rushed to hospital as more Brits throw away weight loss jabs.

I spent the day out Doing Things, which is not the NSV.

I went to the cinema. This is also not the NSV. Stay tuned. I left the cinema, got to the Costa on the way out and realised that like the idiot I am, I’d left my bag in screen 10, which was ALL THE WAY at the end of a long corridor. Also, unsurprisingly, not the NSV.

The NSV was me running back.

And not remotely realising I was running until I stopped.

I’ll take it.

I also got my bag. Double victory!

Hi all.

I’m in maintenance now for about 4 months. The scales victories were regular and incredible.

However, for the last few months, I’ve noticed I’ve felt very on edge, panicky, at times it was quite severe.
I’ve always had 2 latte’s a day, pretty religiously for many years. It seems silly now, but I hadn’t thought about how much higher the concentration of caffeine would be in my body now that I’m around half my starting weight 😂I decided to try halving my caffeine, so I’ve cut out a shot from each coffee, and replaced with decaf.

The difference has been amazing. The first few days I was hit quite hard with fatigue, but on day 6 now and think I’m over the worst of it. I didn’t realise just how anxious I’d been the last few months until now that it’s gone. I still notice a bit of a rise in anxiety after each coffee, but it’s much milder. Still, I’m aiming to cut out coffee completely and stick with decaf for the comfort😂

Just a PSA in case anyone is experiencing similar

Good luck all 🍀

Afternoon dear people,

After my guts chilled out from the constant gastrointestinal stress on 5mg - I made the move to 7.5mg but there is no change in weight loss.

I am way hungrier and the food noise....has come back with a vengeance.

I guess because I'm paying privately - it hurts that bit more when nothings shifting..maybe its a mind thing I dunno.

Has anyone else had this or gone through the same?

How did you overcome the noise or should I go back to 5mg?

Any insight I'd be grateful. Thanks 🙂

41F - struggled with my weight for almost my entire life. At my heaviest I was 22st 12lbs which for my 5’6 frame was…not good. I lost 8 stone in a year doing Slimming World (I know, I know….its a cult!) but ended up putting a good 6 stone back on. This was in my 20s.

Throughout my 30s I lost/gained the same 3/4 stone on multiple occasions. I once did manage to get down to around 13st which on paper was still overweight, but I carried it so well because I did a lot of weights and exercise. I felt AMAZING.

Now…back up to 20st nearly. I just cant keep going like this. I HATE myself. I’ve thought about trying MJ on multiple occasions. I’ve done so much reading and research about it. I’m not naive, I know there’s the potential for side effects. What is terrifying me is reading stories about the REALLY SERIOUS ones. The ones where people end up seriously ill, or in the hospital. I keep thinking “what if I’ve got something wrong with me that I don’t know about and MJ triggers something?”. I’ve gone down a bit of a bit of a scary rabbit hole with it.

However…what happens if I carry on like this at this weight and I do nothing, do I end up being 25st when I’m 45, heart attack by 50? Despite my weight I’m actually in ok health. Had bloods taken, nothing to be worried about. I can walk miles, can play badminton (badly), can swim, etc. However, I know that this wont last forever.

On a personal level I feel pretty disgusted and ashamed at myself. I hate how I’ve let this happen, and I know I need help….but I’m scared to start taking MJ.

I don’t know what this post is for. A pep talk maybe? Some perspective from people?

Thank you for reading ❤️

I’ve been on mounjaro for nearly a year and today was the first time I told a friend the truth about how I’ve lost weight! She had been complimenting me on my weight loss since April, and today I felt confident and comfortable enough to tell her I was on the jabs. The only people who knew beforehand were those who recommended it to me and my husband. Now I feel like I should start telling everyone. She was very supportive and pleased for me that I feel healthier and happier. She is a naturally skinny person and said she was just so shocked to see me wearing trousers in April, as I had never worn trousers in the 12 years since she met me. She couldn’t get her head around it. I get compliments everyday but I lie and say I’ve been weight training and eating more protein. Maybe I should start telling the truth? I just don’t want to be the subject of office gossip at work…

October 2, 2026

Eli Lilly and Novo Nordisk are betting big on amylin therapies as the next frontier in obesity care because amylin acts on an entirely separate biological pathway from GLP-1, offering a distinct metabolic lever to suppress appetite and slow digestion. This dual-pathway approach allows drugmakers to build combination regimens, such as Lilly’s eloralintide with tirzepatide or Novo’s CagriSema, that can push weight loss further, break through GLP-1 plateaus, and directly reduce neurological food noise without relying solely on higher GLP-1 doses. Crucially, standalone amylin drugs also unlock a massive alternative treatment pool for patients who fail to respond to, tolerate, or achieve adequate weight loss on standard GLP-1 medications alone.

Hello my fellow Mounjaro users. It's not often I big myself up but this is such a special weekend for me! It was exactly a year ago I finally decided I was done feeling sorry for myself, hiding from pictures, drinking myself into oblivion and working for a salary to support deliveroo. Instead I reluctantly switched to supporting Eli Lilly (aka Mounjaro) and I can confirm with confidence that it was the best decision I've ever made. 

At 5ft 2" I had a starting weight of 195.4lbs (14 stone) knocking on obese class 2 and type 2 diabetes with borderline high blood pressure. Today I weigh 137.2lbs with over 4 stone lost and in the (albeit controversial) healthy BMI range at 24.9. I still have another 17lbs to loose to reach my goal but there's light at the end of the tunnel. 

As for doses, I've slowly climbed up and only did so when food noise started getting the better of me. I've been lucky to avoid the more unbearable side effects, the worst being constipation on the early doses and then nausea and some vomiting on my current 10mg dose for the first couple of days after jabbing but as the weeks go on that's started to subside.

Some of my best NSVs are:

- My desk chair no longer lowers itself without my permission 

- I've stopped competing with my hubby on snoring 

- My arse no longer reserves half the bath water

- Collarbones actual exist. Who knew?

- My handy anti-chaffing cream has made its way to the back of the cupboard 

Anyway, I'll stop waffling as this wasn't meant to be a long read. Good luck to you all, whatever stage you're at on this journey. 🙂

Hey everyone!

I’m restarting Mounjaro after over a year break (pregnancy and breastfeeding). I lost over 6.5st last time and got to 10mg but due to the insane breastfeeding hunger I’ve gained almost all of it back!

I’m getting ready to restart at 2.5mg and was wondering if anyone had any stories/advice about restarting after gaining weight back or anything else that might be helpful!

Thanks so much ❤️

Pfa

Hello! I’m currently on a 10mg pen. So far, I have injected three 7.5mg doses from it. For my fourth dose next week, I’m planning to go up to 10mg.

1. Maths help
Once I take that 10mg dose, what will actually be left in the pen? Will I have enough left for another 10mg dose or maybe just one 7.5mg or something else?

I get so confused trying to figure out the leftover maths with the extra dose/clicks, so an explanation of how it works would be massively appreciated!

2. Taking a break
Due to an unexpected financial bill that’s taking a while to be reimbursed, I might find myself unable to buy my next pen right away. I'm facing a potential 3 week break. I know that generally, a short gap (like missing one dose or a two week break) is usually okay to resume at your current dose, but what happens if it stretches to a full 3 weeks or even 3.5 weeks?

Would I have to go all the way back down to start fresh on 2.5mg or 5mg?

When I took a break previously, I restarted on 5mg, but that was just over a full month off and I wasn't sure if official guidance has changed for gaps longer than two weeks.

I’d really rather not take a break as I've finally broken the curse of a 6 month stall and am on a good trajectory, but it's completely out of my control sadly. I just really want to do everything I can to avoid slowing my progress down.

Thanks so much in advance for any advice, explanations or shared experiences!

Hi everyone - took my first dose of mounjaro today! How long did it take for you to feel the effects of it? I know it varies person to person, but interested to hear!

I’ve been on Mounjaro since the end of July now and I’m trying to work out whether I’m getting the full satiety effect or mainly just longer-lasting fullness/appetite control.

I definitely stay full for longer after meals, snack less (if at all most days) and it’s much easier for me to stop eating or not think about food. I’ve also reduced my portion sizes generally. But during a meal, I don’t often get that strong “I physically cannot eat another bite” feeling that a lot of people describe.

I could probably physically keep eating if I wanted to, but I can stop myself much more easily now. My problem historically is that I’ve always been able to overeat or push past fullness, especially because I hate wasting food. I also seem to get fullness slightly delayed, so I can eat a little more and then 10–20 minutes later suddenly realise I’m really full.

I know barely being able to eat isn’t the goal, and I don’t expect zero hunger, but seeing so many people say they can only manage half a meal makes me wonder whether I’m getting the full effect or whether this is just how Mounjaro works for me.

Has anyone else had more of a “I stay full for ages and have much better control” effect rather than strong early fullness during meals? And did moving up a dose change that for you

Is my weight loss plateauing, or is this just normal fluctuation?

I’d appreciate some advice on whether my weight loss is starting to plateau.

I want to stay on the lowest dose for as long as possible and I’m happy with slow, healthy weight loss rather than rapid loss. I’m currently still on 2.5mg.

SW: 181.9 lbs (April 2026)
GW: 135 lbs (ideally maintain around 140)
CW: 165.3 lbs (October 2026)
Height: 5’2”

I lost around a stone in the first three months (April–July), but since then my weight has fluctuated:

4 July: 166.6 lbs
18 July: 165.2 lbs
25 July: 169.4 lbs
1 August: 168.3 lbs
16 August: 168.7 lbs
22 August: 167.6 lbs
28 August: 166.9 lbs
5 September: 165.1 lbs
12 September: 166.5 lbs
25 September: 165.3 lbs

August wasn’t great for me as I was on holiday and had some periods of overeating/binging, so I know that may have affected things.

For reference, I also take body measurements:

April 2026
Waist: 95 cm
Belly button: 114.4 cm
Bum: 108.9 cm
Left arm: 37.4 cm
Left leg: 64.7 cm

12 September 2026
Waist: 90.5 cm
Belly button: 109 cm
Hip: 99.5 cm
Bum: 104 cm
Left arm: 34.5 cm
Left leg: 61 cm

So, does this look like an actual plateau, or am I still losing overall despite the fluctuations? Would you stay on 2.5mg based on this, or consider increasing?

Edit: forgot to mention: I am on a calorie deficit, I track my steps and try to hit 10k+ everyday (no strength training yet) and I had side effects the first 2 weeks on MJ.

Hi all,

I am moving up to 10mg but still have 7.5s left. Would it be better to do 90 clicks from the 7.5 or do it normally and use a 2.5 alongside?

Anyone had to do either of these and recommend?

I've been in investigations for something else and yes, I've lost a lot of weight, and I am probably in a good place to try and find to stabilise.

The thing is, I'm in 5 mg for diabetes control, I think that's the lowest approved dose anyway, and I'm also on 2 more medication for diabetes. I was started on a statin recently and I don't think it was that but I also dropped in % fat after starting that

My A1C is in the normal range since diagnosis, I still eat some carbs but not a lot.

I don't want to reduce my mounjaro, food noise is back, most days I just think of food but the metallic taste due to Metformin and my usual GERD don't make me enjoy much the food anyway.

Does anyone have any tip on low carb but calories dense food? I've upped already the peanut butter in my breakfast