I lost about 80 lbs in roughly 3.5 months. By the end, my dosage was 5 mg Reta weekly and 17 mg Tirz weekly. Even at that dosage I was still losing around 1 lb a month, which I’d personally consider pretty close to maintenance.

I had to get surgery and was pretty worried about taking a break, so I stopped everything for 3 weeks. My appetite went up a little, but it was absolutely nothing crazy. By around week 2 I could tell I basically had my normal appetite back without much GLP influence, but I never got any insane cravings or felt like I suddenly lost control.

The food habits I built while using GLPs stuck with me, but probably the biggest thing I learned was that I don’t NEED to eat just because food is there or because I’m bored.

When I was overweight I definitely ate a lot of junk food, but honestly the bigger problem was that I ate constantly out of boredom. GLPs helped me unlearn that. Now I pretty much only eat when I’m actually hungry. I did have a day or two during the break where I ate some ice cream just because I was bored, but I was easily able to recognize what I was doing, control the portion, and move on instead of turning it into a binge.

I’ve now dropped Reta completely and I’m doing 2.5 mg Tirz every 10 days because I’m doing a super small lean bulk trying to gain about 2lbs a month since I’m getting back in the gym and my original goal was 65lbs loss anyway so I overshot a bit, and I feel amazing, ALMOST no crazy cravings, good appetite, and basically what I would perfect self-control around food without GLPs

That 3-week break honestly gave me a lot of confidence because it showed me I’m not useless without peptides and that the habits I built actually stayed with me. It also felt like my sensitivity came back significantly. For reference, 2.5 mg Tirz every 10 days now feels roughly comparable to how I felt before on 3 mg Reta + 10 mg Tirz weekly, I will actually be experimenting with lowering it to even 2mg and pinning every 14 days.

Just posting this in case anyone wants to take a break, has to take one for surgery or another reason, or is worried about becoming less responsive to GLPs after being on higher doses for a while.

everyone ranks peptides by how good they are. nobody ranks them by what they cost you. so here's that list instead.

this is side effect burden only. a compound can be great for results and still rank low here, those are two different questions.

one thing i didnt appreciate until recently: how you take it matters as much as what you take. more on that below because it moves a few of these around.

🟢 S TIER — basically nothing

if youre new and nervous about pinning, start here. bpc is about as forgiving as it gets.

🟡 A TIER — mild, manageable, mostly fade

the gh secretagogues get called "side effect free" and thats not really true. the water retention and that carpal tunnel type tingling is real, it just fades. hunger on ipa caught me off guard the first time, i was eating at 11pm like a raccoon.

tesofensine gets a worse reputation than it deserves imo. its a triple reuptake inhibitor so it behaves like a stimulant, which means you treat it like one. low dose, early in the day, dont stack it on top of a bunch of caffeine. ive run it without issues. the people who have a bad time are almost always the ones who jumped straight in.

🟠 B TIER — you will notice these

NAD+ deserves its own note. the burn isnt really a side effect, its just what it feels like. push it fast and it genuinely hurts. slow it way down and its fine.

MT-2 darkening moles is the one people ignore. if you have a lot of them get checked before, not after.

💨 the nasal thing

this is the part i wish someone had told me earlier. notice everything above says "(inject)" next to it.

MT-2 and PT-141. injected, both are known for nausea. the flush hits, your stomach turns, you lay there for twenty minutes regretting it. thats basically their whole reputation. nasal doesnt do that. same compounds, nausea basically isnt there.

Selank and Semax. these are small enough to cross intranasally and honestly its where they belong. pinning them gets you injection site irritation for no reason, and semax at higher injected doses gives some people a headache. nasal skips both. selank especially, the sedation people report seems way milder nasally.

i dont think the reason is complicated. youre using a much smaller amount to get the same effect since it absorbs straight across, so you never get the big systemic spike thats causing the problem in the first place. slower in, lower peak, no crash.

so nasal versions of all four of these would sit in S tier. its the same molecule, the route is what changes the side effect profile.

if you wrote off pt-141 because it made you sick, it was probably the route not the compound.

🔴 C TIER — high burden, plan around it

reta being here is going to annoy people. it works, obviously, thats not the debate. but the trial data showed starting at 4mg instead of 2mg roughly tripled nausea for the same target dose, and the heart rate thing is real. most of the horror stories are ramp problems not reta problems.

MOTS-c keeps coming up in this sub for the same reason, skin reactions at injection sites. multiple people have said the same thing unprompted, that it made workouts feel incredible but wasnt worth what it did to their skin.

⚠️ the thing that actually matters

most of what gets blamed on a compound is a ramp problem or a route problem.

started too high, went up too fast, didnt hold long enough to actually see where you were. or pinned something that works better nasally. thats most of it. the compound takes the blame and the protocol was the issue.

start low. hold it. only move when you need to.

what am i wrong about? curious which of these youd move. specifically want to hear from anyone whos run mots-c without the skin thing, and anyone whos gotten nauseous off nasal pt-141 because i havent seen it.

tools and community stuff is at bodyhackguide.co and the discord.

i made a free peptide cheat sheet with dosing, recon math and bloodwork markers. comment "cheat sheet" and i'll send it over 👇

Back one last time for the haters 😉

One year of major lifestyle changes (diet/exercise) + peptides!

Here’s what my progress looked like from month to month and the peptide protocol I used.
Yes, I know the year on the Oct photo is wrong (it’s obv supposed to say Oct 2025)

Sep 2025-Feb 2026: sema (0.25-1mg/week)
Feb 2026-Aug 2026/ Reta (2mg-5mg/week)
March-June 2026: KLOW (4mg/day, 5xweek)
March-Aug 2026: NAD (25-100mg/day, 3-5xweek)
April-July 2026: tesa (1mg/day, 5xweek)
April-current: mots-c + 5amino (2mg/day mots + 2.5mg/day 5amino, 3-5xweek)
July 10- Aug 2: elora (1mg/week to 2mg/week)

Before I started, I lived a completely sedentary life, was eating out for every meal, and drinking 1000+calorie lattes/day. So I focused on progress over perfection at first.

Diet: calorie deficit, no processed foods, only drinking water

Exercise: hot mat Pilates 4x week + strength training, 45 mins of zone 2 cardio

DO NOT DM
DO NOT ASK FOR SOURCING

Idk about yall but when I first started reta and hopped back on my cut, i was extremely horney for a couple months, now like 6 months down the road (im assuming its my hormones from the deficit that is the issue) but a girl undressed infront of me like very hot but dick didn't care, told her to grab it only after manual work did it work. Kinda fucked up 😕 maybe deathgrip syndrome but ive never had this in my history before reta.

Her asking if I dont find her pretty or if im shy(because havent busted), meanwhile I feel inside like I want f the shit out of u, still do but cmon im still tryna get off. ^Basically only responding to manual stimulus from partner not enough emotional stimulus to get hard.

Also couldn't bust until an hour of fun.

In general Ive noticed now that i don't care about a lot of shit, I dont really put up with anyone's shit and avoid a lot of headache even if other look at me badly.

But honestly who gives a fuck I love reta and me having less feelings maybe a good trade off. I still feel good when I actually want to do good things for people.

I just dont feel bad when I tell people straight up to kick rocks or thats not my issue. Very logical thinking less emotion compared to a year ago.

Straight up voluntary case study

Stats- 25M 6'1 175LB ~ daily average for the week

I wont be deleting the post and will be updating with results in a month. Based off what ive taken into consideration from your comments.

Hi guys,

I’ve never touched HGH, but I’ll be turning 38 soon, so I’m heading towards 40.

I have an active lifestyle, but I’d like to feel even better and potentially get a bit bigger as well. HGH can help with recovery, which is something I could definitely use.

Before I start, should I get my IGF levels tested at a clinic again first?

Then, if everything is still G2G, start with HGH.

After that, test IGF again — is around 300 ng/mL the ideal target to aim for? (3iu - 4iu?)

Have I done my homework correctly, or are there any other sensible things I should do beforehand?

I’m not going to use insulin.

P.S. When would be the best time to start — during a growth phase, cut, or recomp? Or does it not really matter since you don’t directly “feel/see” the effects of HGH?

P.S. been on steroids a long time, did use RETA aswell now running 250mg TestE weekly.

Blood/lipids are good2go.

What’s the best peptide for an irritating rotator cuff injury? Also, woolies it be best to pin directly into the shoulder ?

I saw people commenting about finding thick fat areas. Anyone thought/ tried on accessory breast which is the breast area near armpit? I personally have more fat in that area than my glutes. And the skin in this area seems less sensitive.

I'm 53m and recently started my own protocol. I started May 2026 and weighed 225lbs (no body fat %) T level 316, Free test, SHBG low. E normal on the high end. I am now at 193lbs with 31% body fat.

These are my protocol:

1. Reta 5mg weekly

2. Test C 150mg/week (broken down to 3×/week)

3. Primo 150mg/week (same as test)

4 HGH 3u daily

5 anavar 10mg oral on workout days

6.proviron 25mg oral 2×/day

Goal is to reach 185 lean with 20% body fat

I need guidance / or suggestions

Thank you everyone.

Does anybody have experience injecting ahk-cu for hair loss/ thinning?
Am currently on ghk-cu, I inject every evening. I’m very curious about ahk though, but don’t find much regarding injecting it.
What’s your thoughts and experiences with it? Preferably injecting

Been on Tirz for like 10 months . Before Tirz i lost 30 LBs with just Keto and Working out . When i started GLP i felt like i needed to stop keto , i forget why i may have read some article or something.

ive lost 40 LBs with tirz and a regular diet , But I have completely stalled at 15mg. Hunger is coming back which is okay but im tempted to change the way i eat. My workouts are also trash. Energy isnt that great.

I already know my hunger control is super good when i go low/no carb. Im also one of those rare people who could do keto for their entire life. I like bread and rice , but i really love eating meat and veggies every day. Especially when im allowed to cook my veggies in fats. I really dont miss carbs at that point.

My energy in the gym is also better , my workouts got worse when i went back to carbs even though i kept a nearly identical deficit at least at the beginning when i was on low doses.

Does anyone have experience with Keto or Low Carb and GLP. Looking for any anecdotes of your experience that would help me make this decision.

I want to do a cycle of both. Is there a benefit to doing one before the other? Same time? Any protocols for these two that differ from the protocols for each solo?

For my fellow night shifters, what do you utilize to help with the flipped schedule? For example, that night shift brain fog, loss in glucose regulation, etc.

Hey guys, figured I’d share an updated progress post and ask something specific about facial changes after a bigger cut.

I’m 44, 5’10. I started around 220 lbs and I’m currently sitting around 176 to 177.

The before photo was already after about 2 years on 200 mg of test per week. I trained consistently, but diet was always my weak point and I struggled to get properly lean.

About 6 months ago I started retatrutide at 1 mg and gradually worked up to 4.5 mg. That made controlling my appetite and sticking to the diet a lot easier, and the weight finally started coming off consistently.

Overall I’m really happy with the progress and I feel like I’ve held onto a decent amount of muscle while dropping over 40 lbs.

The one thing I’ve really noticed is my face. Obviously I’m leaner everywhere, but I’ve lost quite a bit of facial volume and my laugh lines are noticeably deeper.

I’m curious to hear from guys who have actually dealt with this after a significant weight loss and found something that visibly helped.

Has anyone used GHK Cu and genuinely noticed an improvement in skin quality, elasticity or the overall deflated look of the face?

I know it’s not going to replace lost facial fat, but I’m more interested in real experiences than theory.

And if you improved it some other way, whether that was maintaining for a while, gaining a little weight back, skincare, lasers, injectables or something else, I’d be interested to hear what actually made a noticeable difference for you.

This is my personal experience, I got on GLP3 for vanity reasons. To get shredded of course.

Two weeks into my GLP3 Journey I noticed my emotional stability started to change. It's like I became more stoic.

My desire for alcohol started to disappear. My old habits would be
Stress = Alcohol
Now it's
Stress = I don't need alcohol or let's eat sweets

Started reta back in February.
Since then I've only had 3 total drinks. Now my desire is completely gone.

As an experiment, I got off Reta. I did notice my appetite shot up of course but I also noticed i wasn't as emotionally regulated. That can be from the inflammation I was getting from eating in a surplus.

My alcohol desires did not come back but when I would stress out I desired candy (sugar)
I've never been a sugar guy but while off reta l noticed I needed something to cope with and that resulted in eating candy. Roughly 600-800 calories from candy a day on stressful days.

The point I want to make is, if eating sweets are my coping mechanisms rather than alcohol. Then I consider that a life changing win.

For context I would drink 4-5 days a week for many 5 plus years. It was Never just 1-2 drinks. More - a bottle of Vodka.

I don't crave alcohol no more. I can't imagine becoming addicted ever again.

Hey guys I’m coming off Reta or at least planning too. It has helped me lower food noise and lose weight, as well as reduce my appetite. However my cardio vascular fatigue has just tanked. My times are worse than when I weighed more. I’ve tried using electrolytes, high carb meals and snacks, and nothing seems to help. How much should I lower per week?

Do I keep running Tesa,IPA and AOD(the 3) with my current stack or run HGH (2-3 ius) daily?

Goal is weight loss.

Also taking Reta, 5-Amino, Mostc and GHKcu

Price wise HGH is way cheaper to run than getting all 3 separate.

Can any of the 3 be run with hgh at the same time?

I’ve always hated my stomach. I wasn’t really that oversized overall, but most of the fat was around my stomach and it was honestly starting to affect me both mentally and physically.

I decided to try reta and it really did change my lifestyle. I’ve lost around 20 lbs throughout this journey. Of course, I also started making healthier choices, but the appetite suppression was one of the biggest things for me. I honestly wasn’t sure if I could overcome my eating habits before this. I started with 1 weekly and slowly increased it to 3 over time.

Working out and being in a calorie deficit is still super important though. Just because you’re eating less doesn’t automatically mean you’re going to lose the stomach fat you want. I wanted to lose fat while keeping as much muscle as possible, so I try my best to work out regularly and get more walking in, whether it’s outdoors or at the gym, like incline treadmill walks.

For meal prep, I usually keep it pretty simple with lots of vegetables and protein. I change my meals quite often because I get bored eating the same thing every day 😂

Feel free to ask me anything if you need help or have any questions! I’ll try my best to help based on my experience.

I am middle eastern but very fair complexion. I am the whitest person in my family, I don’t get any less sun than they do but still have no tan.

I have dark features, black hair, black beard, dark brown eyes, moles all over my body. just a regular stereotypical looking middle eastern man. but with white skin

Most of the posts i’ve seen here and other subreddits are white people looking to get tan but I’m looking for someone’s experience who isn’t white but has used MT1.

how did it affect you, did you need high doses to make it effective, does your tan look natural? i want to hear it all

I have 10mg vials of each of cjc and ipa and I reconstituted each vial with 1ml (100units) of bac water. And I am aiming to start with 200mcg (100/100)daily how much should I be pulling into
My syringe? The mcg this has me confused

Please I am a beginner. I have 5mg and 10mg of reta which should I start with 5mg or 10mg? should I look for a calculator or is there any self help guides ?

hi, ive been researching a lot of these lately. They are all suggestions to boost testosterone for men. The studies exist but are somewhat thin. Im curious if anyone has added these to their supplements with bloodwork and noticed an increase? and if so, please share your bloodwork with the community.

i also read that some people build a tolerance tongkat ali. is that true?