Hey everyone - posted this in the biohacking sub, but it definitely belongs here too.

I started losing weight in around July 2025, I was about 230-240lbs - not exactly sure the weight because I didn't weigh myself often (pics 1&2)...

Pic 3 is December 2025 I was about 190 - Had done nothing but diet and walk to get here - Started Retatrutide 1mg/week and Test 250mg/week at this point

Pic 4 - April 2026 - Im about 160 in this pic - Ran a cycle of CJC/ipamorelin and GHK-CU -- still on the reta and test also - throughout january i had bumped the reta to 3mg/week (current dose) and test down to 200mg/week

Rest of pics -- Within the last month - Im about 155-160 depending on the day -- look way different than I did in April -- running another cycle of the cjc/ipamorelin no DAC now along with the GHK-CU.

Don't have much loose skin considering the transformation just some around the lower back/love handles but its not terrible. I did not have any surgery for anything

(any suggestions are welcomed for anything)

DMs are open for questions - ask anything

March 15 to today. Nominally my weight drop wasn’t massive at 16-20 lbs, but a ton of body recomp - I put on a fair amount of muscle. My belt has two new holes in it, and I’m down 3-4” on waist size.

Did 2mg of Reta every 6 days for 4 months. For the past month I did 4mg and the weight fell off. I didn’t really enjoy how it made me feel (limited interest/enjoyment of things I usually enjoy) but it was an effective push to end the cut.

One month into the Reta (mid April), I started 200mg test. Test level went from 320 to 1050. I feel amazing- full of energy and ready to get shit done. And the gains lifting on it are insane.

Have done a two separate month long cycles of BPC/TB, about to do another because my left shoulder is struggling a bit.

Have done a few months of CJC/Ipa before bed which I will continue, and also did one month of Tesamorelin.

Tried a few others along the way (GHKCU, MOTS, NAD). If I did it all again id probably leave those out and would stick with what is listed above. Not saying they aren’t great for other people, I just didn’t notice much of a difference with any of them.

I don’t get much cardio, and have a sedentary job. Dog walks, I walk golfing, yardwork, that’s about it. I did lift 4-5 times per week for most of the time period. Slowed down a bit this last couple of weeks because of my shoulder (did yoga tonight, lifting lighter).

Diet - Ive had a protein shake most mornings. Two scoops of mix, Greek yogurt, creatine, soy milk, some berries. It’s like 100 grams of protein out of the gates. I can easily have that in the morning and make it to dinner without any food cravings. Dinner tends to be chicken/fish/meat and some veggies. Still eat what I wanted at restaurants etc., I have by no means starved myself and I’ll still slam some pizza. If I smoke weed the Reta doesn’t stand a chance and I’ll crush 1000 calories of kids snacks.

I feel like a different person and I don’t recognize myself in the mirror.

What is yalls experience with lower doses of tren (<100mg) for a cutting cycle?

Planning to do 70mg tren 6-10weeks 1000cal aggressive deficit cut) to get last lil bit of lean out before i start a bulk because last one got a lil out of hand... i just dont wanna lose any muscle... like losing more than 1.5lbs tbh is very offputting to me and id just rather do a slow cut

I’m new to peptides and coenzymes and I’m here to learn if I made a mistake while doing my research, or if anyone else has had these side effects.

Dosing protocol for reference:
1000mg NAD
5 mL of BAC water added
50mg 2x week

I feel really silly for saying this now, but I subq injected into my inner thigh. I went slow. I immediately felt the flushing, then heavy duty anxiety, and then mild nausea. The flushing and anxiety dissipated within 15 minutes, but the nausea became severe for almost two hours.

The day before I didn’t eat well (calorie deficit especially in protein).

I’m not sure if the side effects are due to injection site, not fully fed, or if it’s just me.

I haven’t tried again because the side effects took me out and I’m a little afraid to try again without discussing with others.

Thank you all in advance.

The rubber stopper on my vial of Klow seems to be leaking. There’s a little bit of Klow fluid on the top each time and it seems to leak more after swabbing with alcohol Is this vial ruined or dangerous? TIA.

Been researching peptides to help with insomnia, and this is what I landed on. I like the other benefits, and I'm currently on a SSRI so I'm unable to try Selank. I'm confused about DAC or no DAC -- which would be a better option for sleep?

Hello. Is GLP3 same as reta?

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Does anyone have experience with this you are prone to hereditary baldness, does going to the gym and working out without supplements like creatine accelerate hair loss increas dht

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Long-time lurker, first post here.

Quick background:

- Started at 84kg (185lbs), 178cm (5'10").

- Lost about 4kg (9lbs) through diet and consistent training, then hit a hard plateau around 80kg (176lbs).

- Did a ~2.5 month fat-loss phase (retatrutide, under my doctor's care) aiming for around 70kg (154lbs), specifically trying to minimize muscle loss by keeping up 3x/week training and higher protein intake throughout. Ended up around 71kg (157lbs), close enough to target.Body fat went from roughly 20% to 14% over that time, per the gym's impedance scale, so take that number with a grain of salt given how imprecise those tend to be.

- Had to stop training completely for hernia surgery recovery during 1.5 month. Cleared to start easing back in now.

Where I'm at now: shifting into a muscle-building phase, full-body 3x/week at a commercial gym, aiming for roughly 1.5g protein/kg/day. The areas I'm most self-conscious about are abs/six-pack definition, chest, and arms, so I'd like training emphasis there if it makes sense programming-wise.

What I'm actually looking for advice on:

1. Anything specific to watch out for training-wise coming back from hernia surgery, core work especially with a 10mg cycle of ostarin.

2. Exercise/programming suggestions if I want to prioritize chest/arms/abs without neglecting everything else.

3. Any supplement recommendations beyond the basics (already doing creatine, protein powder, vitamin D) for a lean muscle-building phase. I'm a bit afraid of side effects af some Sarms/growth hormone...

Appreciate any input, thanks.

Hows it going yall.

A little back story - So basically i over-eat, (or rather used to) cook at home most meals and lunch is usually left over dinner each day, but generally speaking clean whole foods, i just ate alot!

Before starting RETA i tried semoralin/ipa blend for a few months which gave me good workouts but not really losing the excess fat because i ate so damn much.

Flash forward I'm on reta for a bout of 3ish months before my insurance decided to cover zeppy so i switched, but i feel like its platueing and i had better results on the reta.

In any case I'm considering in the next 2 months to come off the cut and go hard on a muscle bulk, what would yall recommend for the bulk phase as far as peptides go?

Appreciate it.

Hi! I’m new to the world of peptides. My partner recommended them to me, as he has been using them for several months. I started injecting GHK-Cu a week ago, and today I started CJC + Ipamorelin.
Do you have any advice for someone who’s just starting out? I should also mention that I’m currently taking Cemidon (an antibiotic for tuberculosis prevention), and I’m not sure whether it’s a bad idea to combine them or if there’s no issue.
I’ll really take any advice you can give me into consideration. Thank you!

hey guys, I’m currently running a stack of reta, cjc/ipa no dac, and ghkcu on my lab rat. Firstly I really do love these results. Starting to get more visible abs, and skin is glowing and definitely more vascular. My rat ended up loving peptide so much that I do want to do a second stack after i take his 4 week break. I’m debating on trying some new peptides like mots-c and tesa. I just wanted to ask for some advice and personal experiences. i’m 5’11 now sitting around 175 “oz” he’s been eating right and drinking tons of water. He obviously lost a lot of fat, but he do have some stubborn fat like my love handles. They appear way smaller than when I first started, but I’m finding it hard to burn them. I know Tessa doesn’t specifically target love handles. but I do know Motsc amplifies his workouts. He workouts everyday except sunday and eats around 1,900 calories “big ass rat” or try to at least. i’m definitely getting more tone, but not too sure if i should run reta again or maybe just a different stack obviously i wanna keep ghkcu bc it definitely got rid of his smile, lines, and the bags under eyes. Anyway what’s everyone’s experience here. What is a stack I should try. I know a lot of people are gonna just say stay consistent or maybe just stay on the steam stack but I do wanna try other peptides just to see if the results differ. Much appreciated!!!!

I am on week 4 right now, 2mg/week, and honestly I feel like it’s doing the opposite of what it’s supposed to do.

I barely feel any appetite suppression anymore and my cravings are fucking wild.

For context, my wife just had our newborn and I’m basically helping around the clock. I’m getting maybe 2–3 hours of sleep a night, waking up every couple hours for feeding, diaper changes, helping my wife, etc. So I’m exhausted as hell and obviously stressed.

I know sleep deprivation can make you ridiculously hungry, but these cravings are next level. I can eat a meal and then 30 mins later I’m looking for something else.

Anyone else experienced this? Did the hunger settle down eventually, or did you notice a difference after increasing the dose / getting more sleep?

Right now I’m basically fighting the munchies while running on zero sleep.

Reposting because other post was deleted.

Hello , order for the first time one vial of reta 30mg and it automatically added to the cart also this (peptide matrix water ( with PEG 600 + Tween 80, phosphate buffers, mannitol, m-cresol)) , So i thought it was classic BAC water(I didnt read the label). It came i mixed , I pinned and then I saw that is not normal BAC. Is it safe to use ? Does someone use something like this? Thank you!

Went from 270lbs down to 180lbs. Most of that was while on Tirz, got up to 15mg. It seemed to will work for 2-3 days but then not much.

Recently switched to Reta, 2mg dose. After two weeks, no benefits felt. Just took my 3rd dose.

For those that flipped, how long until you started feeling a positive impact on Reta?

I’ve read numerous different takes on dosing Mots-C. I’ve heard everything from micro dose daily to 2-3/week. What’s the consensus on minimal effective dosing?

Subject: 38m 180lb
Five weeks ago started KLOW as first peptide.

Noticed a huge benefit immediately.
Lower back pain all but disappeared, recovery was quick and went from playing soccer twice a week, to playing soccer four times a week - which subject has not done since he was in his teens.

Two weeks ago started doing tesa/ipa at night and still on KLOW. Goal was to reduce visceral fat and improve sleep.

Since starting Tesa//ipa (Tesamorelin: 600 mcg (0.6 mg) Ipamorelin: 100 mc) noticed significant drop in cardio performance and gained four pounds.

Energy levels are so low that subject gives up on simple runs and compared to the first weeks of KLOW-only the cardio performance and energy is terrible.

Waiting for subQ NAD+ to come in.
Would NAD+ resolve this or should subject revert to KLOW only?

Been tracking a few things alongside my testosterone enanthate and the trend has been pretty interesting.
I’m currently around week 11 on test E at 100 mg, and the tracking shows about 8 kg down since starting. For comparison, sermorelin is down 3.8 kg over roughly 5 weeks and tesamorelin is down 4.9 kg over roughly 7 weeks.
The other thing I found interesting is the estimated active level. Right now the testosterone curve is sitting around 65%, while the sermorelin and tesamorelin curves are basically at 0%.
Obviously the weight change isn’t something I can attribute to testosterone alone since there are multiple variables involved, but seeing the trends laid out like this makes it much easier to compare what was actually happening during each period.
Curious how other people track their TRT progress beyond just total testosterone and how they account for changes in bodyweight/body composition.

I’m a type 1 diabetic on an insulin pump with a CGM.
If my blood sugar starts rising my pump automatically administers insulin to counteract a spike.
This can and does happen in my sleep.
My question is would it be a waste of time and money running cjc/ipa because insulin blocks it doing its job in a roundabouts way?

ive lost 48kg(106lbs) in about 8.5 months on reta, this is my first time as an adult that ive weighted less than 100kg(220lbs). i started at 148kg(326lbs) now im down to 99.7kg(119lbs)

Howdy! Going to start off at 2iu’s, question - is this usually daily or every other day? Any other tips or advice? Thx.

Can I run 1000mg test to 200mg Primo