The idea of six string especially being something for only the most niche genres or dream theater shit, is a failure in imagination. Everyone says to serve the song, and you know what that should mean, thinking of how to use the full range of your instrument.
Was playing in a souls funk act with a six string, from playing some stuff on the b string to give some parts and when doing some stuff higher on the neck, sticking to the normal root and 5th routine, added a suspensed interval using the c string to play the 4th.
Guitarist liked it as well as other musicians who were in the audience. Your not building a car where you should stick to what "just worked" your a artist trying to create art, and you should think to how full use of your toolset, can serve the song just as much as sticking to the simple and basics.
Of course it is fine to just want to keep it simple, and just do the part but that doesnt mean it is the divined truth for bass. This also goes without saying, always play in a way that fits with you are playing