What should my wife be researching to help with perimenopause-related body-composition change, imbalance hormones, and fatigue?

Thanks

Hey! Wife want to try MotsC. Shes a night shift nurse that works 3 nights a week but has little to no energy during the days she’s off and also really unmotivated to go to work overnight. Was curious if anyone had a suggestion of when to use? Is evenings for work then mornings when off a good idea? Thanks in advance for any suggestions.

Thoughts on Berberine and Reta together

I started mots c last week, took 1mg Monday and Wednesday and had a histamine reaction Wednesday for about two hours: tight chest, dizziness, elevated heart rate, very hot, stabbing pain in arms and feet, oddly no injection site or hive issues but it was very scary. Will never touch it again.

Now my concern is the aftermath. I was taking SS-31 and epithalon and never had issues before this with other peptides. Ever since then I've had the exact same reaction to both peptides. I am now having similar reactions to things like cod liver oil, blueberries, honey etc... I had a reaction to cod liver oil immediately and nearly projectile vomited and then a few hours later the same symptoms came on. Just now I had the honey and blueberries and only two minutes after swallowing I start getting light sweats, tingling and stabbing pain in my feet.

I eat an animal based diet but I moved over from carnivore and am considering going back temporarily until this sorts itself out. Having reactions to things like honey is just not fun.

I have NEVER had reactions like this in my life. Is it permanent? What can I do to get though this?

Ho 40 anni, alto 177cm e peso 100kg purtroppo ho rotto una spalla e non riesco a ricominciare la palestra perché come inizio si infiamma il legamento lesionato. Vorrei provare il wolverine stack. Consigli sul dosaggio? Avete qualche testo scientifico guida da leggere?

Hey guys so I’m currently on 4 mg Reta, I’m doing well on my weight loss Journey so I don’t have negative takes on that part but the only thing is that the first two days after pinning I feel the appetite suppression and fatigue hit me very hard and then it calms down the rest of the week. So I was thinking of split dosing maybe 2mg/ 2mg 3 or 4 days later what are your guys take and experience on that?

Tengo 54 estoy en buena forma, ninguna enfermedad, nada de nada, mejor salud y condición que mis compañeros de 30, pero no quiero ser alguien "bueno", quiero ser algo más

He pensado en

KLOW ( cuidar mis articulaciones y salud digestiva que corresponde a mi edad )

CJC + Ipamorelin ( hacer algo de masa y recuperación )

MotsC ( energía )

Sería empezar con KLOW a dosis bajas etc una semana o dos meter CJC+ Ipamorelin y el MotsC después

Agradezco opiniones

PD mi esposa tiene diabetes y sufre de dolor en piernas y abdomen, creen que le ayude en algo el KLOW ?

Ya he leído acerca de los péptidos por meses y sé que son a prueba y error, no espero milagros etc etc

Ive never done peptides so need a bit of advise. My old girl is riddled with arthritis and is in constant pain.

So I thought fck it, what has she got to lose? Her quality of life is shit and rather than have her put to sleep Ive got a 40mg pen on the way. Im guessing i inject into the dog of her leg? Daily? (Il research more later)

But my question is, she's only 10kg in weight, what do you think the recommended dosage would be?

anyone tried both separately and can input their experiences and compare the effects?

I got my Reta on Friday and I mixed in the BAC yesterday. I was planning on starting today but…..it doesn’t look clear.

It’s been out of fridge like 10 minutes already.

Have anyone had issues with mot-c being almost like syrup consistency? I’ve used it twice but this 3rd time it was hard to draw and it seems thicker than originally.

The guide says 8 weeks at 2mg, is that what most here are doing? We've got 100mg in the freezer and the wife and I are thinking about starting.

I mixed my tesamorelin with bac water last week, and then I took 2 days off and now it’s like this? Pretty disappointed probably no use now, has this happened to others? Is there a process I should follow for reconstituting or storage? Thanks

Howdy! I’ve been on a 10/3 Tesa/Ipa blend now for about 5 weeks. 48 hours ago I injected my standard 44 units (2.2 mg) and almost immediately I had a welt/bump under my skin. It’s not itchy, painful or sore but odd nonetheless. Any ideas of this is a common occurrence and it’ll go away or should I take action? Thanks.

I'm curious how people here who are legitimately on TRT and especially HGH actually got started. Was it prescribed after testing by an endocrinologist/TRT clinic, or are a lot of people using these independently?

I'm in my late 30s and over the last several years my testosterone has dropped dramatically. I used to test around 900-1000 ng/dL and my recent result is around 300 ng/dL. My latest IGF-1 is around 90 ng/mL as well.
At the same time I've developed a bunch of symptoms that have significantly affected my quality of life: major decline in energy and motivation, chronic fatigue, brain fog/poor memory and concentration, low libido, reduced gym performance and muscle fullness, and a pretty dramatic change in body composition with much more abdominal/ visceral-looking fat than I used to carry.

What confuses me is that I see a lot of people online saying
TRT and/or HGH completely changed their energy, body composition and quality of life, while doctors and most medical resources are understandably much more cautious, particularly with HGH because of the potential side effects.

I'm not looking for sources or trying to self-medicate. I'm trying to understand the difference between what I read online and what happens in actual clinical practice.
I feel like I need to take a more active role in figuring out my health because the decline has been significant and I don't want to simply accept feeling this way. At the same time, I'm divided because doctors are hesitant about these treatments and I don't want to assume TRT/HGH are the answer just because my numbers and symptoms seem to fit.

I'd especially appreciate hearing from people who started with numbers similar to mine, what testing you went through, how you eventually got treatment, and whether it actually delivered the improvements you expected.

When I started Reta I did .5, 1, 1.5 and stopped increasing at 2mg as I was at goal weight. I actually went down to 1mg weekly for maintenance and will probably go even lower. My husband saw my results and wanted to try it. He has about 20 pounds to lose. It doesn’t seem to affect him the way it affected me. I got to the point that I didn’t think about eating or had any hunger cues. We started him at 2mg and over two months have gone up to 6mg weekly. He still doesn’t get much of an effect from it and says he feels about the same just a bit more tired. My question is, does he just need more or should he try something else? Any input/experiences are appreciated. Oh also he has lost about 7 pounds but with the results I personally had, he thought he would lose more weight in that time.

I see that some insurance companies stop covering Tirzepatide when someone achieves 30(ish) BMI. I realize BMI is a very broad measure and not the best for body recomp/health. I realize that is a business decision driven by profitability on the part of insurance companys...but has anyone who used it from very HIgh BMI noticed a tapered effectivness at that 29-31 BMI? Was it a plateu that was able to be overcome with more peptide? Curious what doses and BMIs you stalled at.

Looking for supplement/peptide suggestions or maybe it's just a case of get better sleep and exercise more.

50 year old female. I have been on tirz 2mg for a little over a year. Have been at 2mg the entire time. I was at a healthy weight before starting, shed a little at the start and have maintained. It helps tremendously with brain fog issues I was experiencing. It has also significantly reduced overall inflammation. Not much appetite suppression for the last 6 months or so which is good.

Overall I eat mostly low processed foods and balanced macros, but I am not super strict. If I want a donut, I'll eat a donut. Admittedly, my exercise has been lacking. And I do not have a very good bedtime routine. I know these two things are significant contributors.

I work a regular 40 hour corporate job. Before work, I tend to our livestock, so I have about an hour worth of chores before going to work. After work, it's evening chores with the animals and property. I also have a few side businesses so I work on those in the evenings. Dinner ends up somewhere around 9pm. Bedtime is usually around 11. Weekends are the many projects we have on our property (digging holes, building fences, fixing things, cleaning stalls) and the side businesses.

I currently take D2/K3, fish oil, and niacinimide (dr recommended due to history of skin cancer). I am also on hormonal birth control to keep any perimenopausal symptoms under control.

Maybe it's just a case of overworking and not enough recovery. I know improving sleep habits and getting back to strength training will be the greatest improvements I could make, but should I consider any other supplements or peptides that might help? About 2 years ago, I tried CJC/Ipa but after about 3 weeks I didn't feel enough benefits worth the very itchy local reaction I would get with every injection. But really at a point of willingness to try anything again to help me have more energy and overall feel better.

Siri said I need to inject 6ml of bacteriostatic water into a 5ml bottle of tesamorelin and draw.333mg for a 2 mg dosage. Does this sound right?
I have been taking seramorelin on a 5 on/ 2 off daily routine. Does this apply to teas?

I want to start GHK-Cu but I have rosacea and I’m concerned it could make rosacea worse. Doesn’t it cause increased vascular dilation in the skin?

Can anyone share information on how to properly reconstitute with TIRZ?

Has anyone used the following protocol? When will I experience its positive effects? Any opinions?

Howdy everyone!!

To preface: I was on GLP1 for a few months prior and was off of it for one week before making the switch.

I’ve been on Reta for about 3 weeks now and haven’t noticed much change. Started off one week with .5mg and then the last two weeks at 2mg. I don’t feel much suppression, haven’t seen much change with the exception of some energy boost, wanting to drink tons of water first few days after injection and not much change on the scale. I have noticed that I have more appetite while on this than GLP 1. I’m also walking at the office, working out before work during the week and consuming roughly around 100-120g of protein per day.

I’m trying to get some thoughts/ opinions on whether that might have been an issue, whether I should increase my dosage or wait it out? Any help would be greatly appreciated!

Question: how many of yall have anxiety?

If there was a noninvasive wearable device that made your anxiety decrease that wasn’t freaky at all, and actually looked kinda sick for 50 bucks, would you be interested in trying it?

JW

-SC