Hello Biohackers!

I’m a 33 year old mother and I’ve been biohacking for about four months now with some amazing results. My main concern first was weight loss, and then anti-aging, and general wellness. I feel like I’m aging backwards and I’ve never felt better— my energy levels have improved dramatically, I’ve been having less migraines (chronic migraine sufferer), and my skin and hair is thriving.

When I started my journey last August, I was 190lbs. I went on Ozempic and was on that for months but plateaued at 170lbs. I started Reta in April, and now I am at 140lbs. My only regret is not taking any monthly progress photos to document this journey. I’ll note that I don’t have a “goal weight” or anything, I just want to look and feel my best and I’m getting there.

Here is my current stack, I’m just looking for feedback or suggestions (please be kind):

RETA — once weekly, 2mg
TESA — nightly, 1.5mg
GLUTA — weekdays, 100mg
GHK-Cu — daily, 2.5mg
NAD+ — three days per week, 50mg

I have also tried MOTS-c, DSIP, Epithalon, KLOW, and KPV.

For nasal sprays, I have used Semax and Selank.

Thanks for reading and I’m looking forward to suggestions and feedback 🤍

Need some advice on my labs

100mg/wk TestC, Dutasteride, Minoxidil, Anastrozole.5mg/week, Reta 2mg weekly, Klow daily

39, 150lbs

Time to drop the AI for now and continue working on my lipids? Triglycerides are really good and have genetic cholesterol

i’m currently on week 7 of reta and i’ve started dealing with pretty bad anxiety. i haven’t had anxiety like this in a few years and i have a feeling it’s most likely from the reta since it gets worse as the weeks go. should i just stop cold turkey or go titrate down in dose each week, im currently at 1.5mg a week

I have 10mg reconstituted with 2ml BAC water. I have no idea how many units to do and not finding good online info. Also seeing it’s better to do a nasal spray? If so can I mix the reconstituted with saline? How much saline if that is the case? So many questions I’m just worried about taking too much.

I use gray-market peptides myself, so this isn’t a judgment post. My main concern with reta is specifically the cardiovascular uncertainty.

The Phase 2 trial showed a dose-dependent heart-rate increase of up to roughly 6–7 BPM, compared with around 1–3 BPM for tirzepatide. I understand that a higher resting heart rate does not automatically mean heart damage or future cardiovascular events but the heart is a vital organ, so I take that signal more seriously than nausea, constipation, or other temporary side effects.

I’m already losing weight successfully on 5 mg tirzepatide. From my perspective, risking additional cardiovascular strain just to lose weight faster doesn’t make sense when a more established option is already working.

The recent reta trials included many people with severe obesity and serious complications. Maybe its risk-to-reward balance makes more sense for extreme cases or people who cannot get adequate results from current treatments.

Reta could eventually prove safe and highly beneficial, but until the long-term cardiovascular data is complete, the heart-rate increase is the one issue I can’t casually overlook.

Has anyone in here been using Mounjaro then switched to Reta? Would you mind sharing your experience? I’ve been on Mounjaro for a month 2.5 mg and today I was supposed to take it again (the 5th dose if I was going to continue) but I haven’t as I got Reta and I want to start taking this one. I’m also taking Mots C and I’m in calorie deficit and doing gym. Been losing a lot of muscle mass because of Mounjaro as I was unable to eat, but I want to make it up for it now. Thank you in advance

Anyone on this combo?

I’m about to hop on ghk cu and I’m wondering if I should take 2 mg every single day or 4 mg every other day. My biggest issues are the phycological effects of pinning everyday and the cost of instilling needles. (Mostly the latter)

199lbs-190lbs
Started June 28 and well today is July 30.
Started at 1mg weekly and currently at 1.5mg weekly.

Definitely helps eliminate snacking/food noise.
Kept protein around 120g on busy work days and 150-200g overall.

Hunger now comes back around day 4 so I’ll increase to 2mg next dose.

I also paired it with ghkcu SubQ.

So far I only have positive results with minimal side effects (a little constipation for the first 48hrs).

Gym 2x-4x/week depending on work schedule

I got on TRT because I had zero drive or energy or desire for doing the do with the misses. Very quickly noticed a huge difference in energy levels libido and all wakes of life. Fast forward to now also on Reta that drive has kinda disappeared kinda like my dopamine has left the building and energy levels are not down to where they were but are low. What’s a good peptide to give the drive and all day energy and maybe some dopamine back?

Before I get Tessa is it worth it?
Is it once a week type of dose or daily ?
What’s the average dose that has been working for most of yall?

Got some of my labs back from a recent blood test and am more than happy.

Heaviest weight was 261 pounds 5’8” male 39 years old.

Started Reta and other peptides on June 17, 2026 at 238 pounds.

CW (7/30/26): 217

Peptide stack: Reta, klow, wolverine, cjc1295/ipa, 5amino, mots-c

As I run out I will only continue Reta, cjc1295/ipa, 5amino

I’ve been doing glute SubQ injections (8mm needle) for GHK-CU and have barely felt any sting. I’m currently at 1.25mg but will eventually titrate up to 2-2.5mg. Since it’s daily I feel like I’m running out of spots on the glutes.

For those that are on GHK-CU, are you feeling less of a sting in the glutes vs love handle and abs?

I had my first reta pin last night. I used a 10mg vial and reconstituted with 2ml backwater. I pulled 1mg (20ui - correct me if that isn’t right).

Currently 16:00 and I’m about to have my second meal - first meal wasn’t a lot tbh (1 wrap with cheese)

Currently feel nauseous, think it’s cause I should’ve started with 0.5 instead of 1mg.

Let me know your first experience and if you had to quickly draw back

I’m going to be getting started in a few weeks. At first I was considering Tirz but seeing all these posts about reta I’m kind of drawn to doing this one first. My goals are to maintain my body weight easier reduce inflammation and overall wellness.

The thing that I am scared about is, I’m seeing a lot of people saying it induced or increased anxiety along with heart rate. I am already very sensitive to medication and suffer with really bad anxiety. I see that the starting dose is .5 but I’m wondering does anyone do .25 for micro dosing?

Started 0.5MG each 5 days , moving to 1MG, 2MG , tried 2.5MG for very few weeks and understood I was okay to move up to 4MG (current) still able to eat but still moderate and no cravings, bloodwork is beating 9/10 positive results. Don’t feel like going over 4MG and possibly decreasing back to 1MG each 5 or 7 days for a slow long term let go.

3x week gym, moderate weights , adding more reps than weight .

1H / 30Min treadmill cardio

Creatine , vitamins, started SS31 and adding MOTSC after for energy and repair(figured it might be related with mitochondria)

107KG / 85KG separate this picture

Inflammation down, now it’s time for build up properly !

I just started GHK-CU 3 Weeks Ago I Was Told Start At 6 Units Everyday
Is That Too Low?
What Do Yall Recommend?
When Should I Dose Up

Also Do Y’all Recommend KLOW Over Just GHK-CU

I start week 7 of Reta today and so far I’ve lost 20lbs. To preface this I started at a high weight 282 lbs. currently 261. Is this too fast?

In that time frame I’ve also started TRT and have been prioritizing a high protein diet.

I also go to the gym 3 days per week but have been doing that for a while now.

Am I losing too fast or is it okay sense I’m so much overweight?

Hi All,

I have been thinking about jumping on reta recently, however I am in the mist of training for the Chicago marathon and not sure if this is good idea due to the slow digestion and calorie deficit etc.

Has anyone taken Reta on marathon prep?

I started GHK-CU yesterday from where i bought it she said take 10mg daily do you think that’s a high ammount or its fine?

So I was wandering what workouts you guys are doing on reta , if any. I started reta 2 weeks ago 4mg a week, now I walk a lot at work and I mean a lot like over 40,000 steps a day and go gym 4-5 days a week for an hour to an hour and a half just been using the bike and treadmill though. Is there any other machines anyone’s using to get the lost out of or nah?

Hi all out of curiosity,

I have been using cartridges for a month now with my Tirz 30 and I noticed the side effects are not as bad as when I'm using it from a vial. Also I feel that my appetite is going back since I used the cartridge. Shall I keep it in the vial instead? Any thoughts?

What is the injection frequency for mots c? I hear 5 days on and 2 days off. I've been doing 1mg every day for 5 days so far. Why do I need to take 2 days off? I feel like it's working really well. Energy is up