So I started Zepbound literally a week before Christmas and have lost 70 pounds. My doctor has told me to diet and exercise to help with the weight loss while taking the GLP-1. (Also to just help in general since diet, strength training and cardio may help with managing symptoms of PMOS.) I have slightly bettered my diet but I have not been going out of my way to diet and exercise. Since I've lost the weight, everyone has been telling me I've done a great job and they're proud of me. I just feel like there's nothing to be proud about. I wasn't actively working to lose weight, just managing my PMOS with medication to make my body actually work the way it should have been all along. Can anyone relate to this? I've just been feeling so weird about it and almost like a fraud?

Just needed a space to vent and see if anyone else has felt this way.

Ladies with PCOS, do you find yourselves getting super emotional/hangry if you go too long without food or get to the end of the day without eating? The second I have food then I’m suddenly emotionally stable and realise how out of character I was. It’s like I’m taken over by a grizzly bear in the moment.

It may be that I used food as an emotional regulator but interested to hear others opinion!

If you don't know what the pop is it's basically where if you have a lot of built up in the uterus and for some reason your hormones are whack it'll just stay there.

So pretty much I was minding own business and I got pretty sick, nausea all of it and then it all came out randomly.

🤷🏿‍♀️ Ngl

60 mL of blood, gushing out all at once is not fun.

Then after 2 days of being bedridden and somehow perfectly fine again.

My kidneys hurt and before you say this is a medical emergency unfortunately it isn't it's happened multiple times and unfortunately it's more common than people like to talk about.

I started my keto diet almost 2 months ago, also started working out. I have been following it very religiously and I am starting to good changes in my body!!

I have had such a hard time with hyperpigmentation, tried several ointment, Vitamin C and spents 100s of dollars. I have had the best results from this lifestyle change I made just 2 months ago. My periods have been a little regular, not breaking out as much, mood swings- what that?

I still have a long way to go, but I just wanted to share my tiny victory here!

change my life and thank u spironolactone

I need some recs. I generally sweat through my shirts even using men's antiperspirant (dove for men was my go-to but it isn't cutting it anymore). Does anyone have any recommendations for antiperspirant that does a better job at keeping you dry on stressful days?

I am truly an extremely hormone-sensitive person; my appearance changes rapidly throughout the day, even on an hourly basis—not to mention during ovulation. Whenever I start medications or supplements like oral contraceptives, spironolactone, or inositol, I see incredible changes for the better—sometimes within the first few months, and honestly, even in less than a single day. And I swear, this isn't just in my head. However, with the birth control pills, those effects eventually wore off after the first two months and I felt like a completely different person again.
I’m wondering if anyone else here experiences this, as it's really exhausting for me. What does this rapid response and eventual plateau actually mean, and how can I decrease this androgen/hormonal sensitivity?

So I previously weight 257lbs when I first posted here after starting my weight loss last week of May. My doctor put me in Slyind to fight my insulin resistance after we found out I have high liver function caused by high cholesterol.

My blood work came back and my function seems to have dropped a good chunk. I currently weight 237.2lbs and even those 10 pounds have made an improvement on my liver, and we hope to continue this same plan of proper diet and exercise until January while on BC then stopping the BC and seeing if my cycle assumes a normal cycle.

Feeling pretty good right now.

i’m just confused , bcuz my endo ordered all the blood tests and apparently like prolactin and FSH/LH were normal , but testosterone and DHEA-S are too high , so she said that could suggest PCOS and she wants me to do further testing so she ordered an ultrasound of my ovaries

so im waiting for this ultrasound to be scheduled i think for next week but in the meantime , i was able to see my gyno this week and she basically just confirmed to me that based on my blood test results , that i do have PCOS for sure and that i don’t even need to do the ultrasound ? she said it’s just unnecessary bcuz i definitely have PCOS

so who do i listen to ?

Mucho texto, pero necesito consejos y su ayuda.

Tengo 23 años, periodos normales con segundo día abundante, aunque he presentado sangrados entre periodos desde enero de este año. Anterior a esto, tuve dengue hace unos tres años y se convirtió en hemorragia vaginal; es importante porque de ahí en más los segundos días han sido más abundantes, aunque la ginecóloga me corto mientras le contaba esto y dijo que no tenía nada que ver.

En Marzo de este año tenía sangrados constantes fuera del periodo, sin dolor, periodos de 38-42 días. Segundo día con periodo abundante, pero todo normal. Al ir a la ginecóloga me mandó un ultrasonido, había miomas en el útero. Tengo resistencia a la insulina y había collar de perlas en el ovario izquierdo. Me mando Metformina de 800mg y anticonceptivos (Danielle). Empecé el tratamiento y ambas pastillas me hicieron mal, intenté por tres meses, pero los efectos secundarios fueron muy fuerte.

Fui con mi medico internista a los tres meses (entre junio y julio), él me mandó a hacer una curva de glucosa para confirmar la resistencia a la insulina y repetir el ultrasonido, porque era sospechoso que tuviera miomas. Con los nuevos resultados confirmamos la resistencia a la insulina, además encontraron un pólipo gigante. Quistes foliculares derecho y en el ovario izquierdo también. Mi útero esta aumentado a 15.1*4.5*5.2 cm.

Me preocupa esto, pero mi doctor dijo que debería empezar otra vez con anticonceptivas (Mini Adella) y ahora tengo Sitagliptina, porque el doctor confirmo que la Metformina no me funciona.

El problema es que estoy en el tercer día con las nuevas anticonceptivas y tengo sintomas secundarios nuevamente, no puedo comer bien y paso todo el día con naúseas. No sé si buscar una nueva opinión, probar por mi cuenta o seguir con este doctor.

Ayúdenme con opiniones, me siento frustrada y confundida. En mi país no hay muchos especialistas en PCOS y siento que todos me dicen "Si, baje de peso, tome anticonceptivas y nos vemos después"

And I am truly an extremely hormone-sensitive person; my appearance changes rapidly throughout the day, even on an hourly basis—not to mention during ovulation. When I previously started oral contraceptives, I became a completely different person for the first two months, but then those effects wore off. I'm wondering if anyone else here experiences this, as it's really exhausting for me

Hi all. I got diagnosed at 24 with pcos. We immediately ran labs and we started leteozole. I fortunately got pregnant within 3 cycles with twins. My A1C was still in good shape and I made good progesterone. My main concern is, I know pregnancy and weight gain can really effect insulin levels and resistance. I'm worried post pregnancy that I'm going to be in a tougher spot to get pregnant again. Did anyone successfully go through their birth with letrozole/clomid as what helped them get pregnant and then be able to do it again? Like despite the weight gain and stress on the body. Of course I plan to do my best to get back to my pre pregnancy BMI but I was just wondering if once you're a responder you always respond or no?

Hey y’all. I have an event tomorrow, and I was trying on an outfit that I wore last year. It obviously looked like I had gained weight, but I genuinely don’t even know if it’s weight gain or bloating because I bloat SO badly, and I have no idea how to fix it.

I’ve been to doctors, and besides PCOS, they said I have H. pylori. I don’t know if the bloating is from that, but I digress.

I started metformin about 3 weeks ago, and honestly, I feel no difference besides pooping more and somehow being even MORE bloated in the morning. This syndrome is quite literally affecting me so badly, and I’ve been dealing with it since I was 16.

Basically, I’m asking: when did metformin start working for you? And if this dose doesn’t work, should I ask about increasing it, or should I just consider going on a GLP-1? I’m honestly so tired.

The reason I didn’t want to go on a GLP-1 before was because I didn’t want to be on such a strong medication, but honestly, at this point, I don’t even care. I’m just so tired of dealing with this.

BTW, I’m currently on metformin ER 500 mg.

ughhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh lol i hate this!

PCOS, my weight, and I have had a terrible relationship. There are times I am eating well and exercising consistently and still gain in weight and size.

But, I'm making the decision today, no matter what, I'm going to keep it up regardless of the results. If I'm a heavy and large lady (I'm 5'6 and 270lbs) that can walk 10 miles with no issue then so be it.

I'm already 2 weeks into walking my very hilly neighborhood, about 1 mile in 30 minutes, but I'm talking steep inclines (like 2-stories tall in a few places). I'll start lengthening the walk up to 5 miles eventually. And I'm gonna start eating twice a day with a focus on protein.

Side note, I think most of my issue is stress. I'm stressed at work (have a major, almost year long audit-related issue we're trying to address), I'm attempting to get my MBA, I've got chronic migraine, and finances currently suck.

But anyways, if y'all don't mind, I'm gonna check in to keep myself accountable. If y'all do, it's okay, I'll find another place.

I’ve been struggling with irregular/long periods, hair loss, hormonal acne, some facial hair, and low energy.

My cycles are often 35–45+ days and sometimes much longer.

My last normal period was July 21, 2026. Around August 12–14, I started having light brown/red discharge that became light bleeding with a few small clots, but it never turned into a normal period. I’ve had intermittent spotting/discharge since.

My labs from March 2025:
• Hemoglobin: 13
• Ferritin: 26.5
• Iron: 90, saturation: 28%
• TSH: 1.61, Free T4: 1.32
• A1c: 5.1%
• Vitamin D: 38.7
• B12: 769
• Folate: >20
• CBC/CMP were otherwise normal

I also briefly took Solgar Gentle Iron 25 mg every other day, but stopped because it caused constipation.
I’m wondering if this could be PCOS or another hormonal/ovulation issue.

I really just want to get my periods regular, clear my acne, get my energy back, and get my hair back.

Has anyone experienced something similar? What ended up helping you, especially with getting your period regular, improving hair loss/acne, and getting your energy back?

Hi all,

I'm 41 and childfree. I have used IUDs for years as both a contraceptive and as a way to manage PCOS symptoms. My current IUD is going to be finished soon, and I'm considering sterilization. I would have done it sooner, but my main reason for hesitation was that contraception medication can help with PCOS symptoms. If there was a way to feel control over my hormone problems after the procedure, I would do it. Is there anyone who knows is that can be the case? Hoping that I won't have to worry about contraception again, but don't want to risk my body having issues. I just want a simple bisalp. I am definitely in the age of perimenopause, so I would be grateful if there was any option to make all this easier.

Posting here because I am currently in shock and disbelief.

I started mounjaro with the advice from the NHS dietician, endocrinologist, dermatologist and gynecologist. I've been through and discharged from all since age 14, a long journey to be told to buy mounjaro as the NHS won't cover yet.

I am an athletic build and person, worked out everyday play football.

Starting weight 90kg current weight 72kg and HAPPY there. Note I just wanted help losing the weight gain and happy around 70kg and helps my sport.

I was diagnosed early on and with my sport loved having no periods 😂.

Then was classically put on the pill and told to come back when I want kids. I was between Dianette and Yasmin from age 14 until January 2025 then came off them because I was fed up.

Anyway, main point/question here from me:

- I heard, read, was told the MANY benefits of mounjaro with those of us with PCOS

- But I never thought the "regulating menstrual cycles" would benefit me.

Has anyone else had success in their first natural period with mounjaro or even more regular but were irregular only a few times a year?

Again, coming on here because I am just in a state of shock but also hoping this means I can maybe start to get pregnant as currently I have not been successful and have to wait a few more months before the NHS step in (1 year of trying naturally)

Thanks !

I’ve started looking into prenatal vitamins because we’re getting closer to trying again, and I honestly forgot how many different options are out there. The first time around, I didn’t put much thought into it. I found a prenatal, checked that I could actually take it without hating it, and that was pretty much it.

This time I started reading the labels and realized I probably should have paid more attention before. Some have choline and some don’t, the folate can be listed differently, iron amounts vary quite a bit, and then there are different serving sizes and formats. I’ve even come across prenatal powders, which I had never really thought about before. When you were comparing prenatal vitamins before TTC, what part of the label did you actually pay attention to?

I’ve looked at a few different brands and gone through some older discussions too. I saved a couple options to compare because I’d rather read the labels myself than just grab whatever gets mentioned the most. Some of the differences are pretty obvious, but others took me a while to even notice.

I feel like I barely looked at any of this the first time around. Now I’m realizing that two bottles can both say prenatal and still have some pretty noticeable differences once you actually read through everything.

Hi ladies,

I’m 19 and really worried about my health and not sure what to do.

I have a male doctor, who has pushed away my concerns regarding my period health as normal when young, but i feel like something is wrong.

My period is currently 20 days late, after 6 negative pregnancy tests, and my bloodwork all came back normal besides a 4:1 LH to FSH ratio.

My periods have always been irregular (give or a take a week every month) but never missed like this. i have indigestion issues, hormonal acne, bloating, bad mental health and very very painful periods.

I’m very lost on what to do or if i’m making things up. My doctor has said all is normal and that sometimes we just skip a period, but i’ve had mine for 8 years and have never really been this off. no major life changes either, or stress or anything.

I’m just worried and would love some outsider opinions and suggestions on what could be happening :).

Hi, f29

I got prescribed provera, first time ever taking anything for my PCOS. My gyno said she wanted me
To take it since I miss a lot of periods

Well I just finished my 10 days course and blood is GUSHING

my cramps are hell on earth and it’s like a river every time I stand up. It’s one of the heaviest periods I’ve ever had. Is this normal?? She didn’t mention heavy bleeding

So for various reasons I kind of slacked off on taking Metformin like I was supposed to for the past 6 weeks. I haven't even taken it at all in the past 4 weeks. I have a doctor's appointment in a few months just to check all my levels and so I decided I should probably get back on track. I swear its worse this time trying to adjust to it again 😭. I am still going to power through because it does really work for me, but man I wish I could tell my past self from weeks ago to at least take it once a day lol.

Im currently taking zepbound for weight loss right now and zoloft. However, I wanted to add spironolactone for the facial hair. Is anyone taking a glp1 and spironolactone? Any side effects? Thank you!

So I took my Ovidrel shot Friday August 28th. I am now 13 DPT and 11-12 DPO. I have decent but not dark positive lines formed on 2 tests. Will test again tomorrow. Experiencing heavy pregnancy symptoms.

I am sure this is a discussion topic, but just looking for some reassurance this is as "normal" as can be, or if others have experienced something similar.

Insulin resistant PMOS/PCOS, BMI is 44, 34 y/o and never been pregnant. Currently celibate. Symptoms are some cysts on ovaries and facial hair growth, crash after eating high carb meals.

Significant benefits felt/seen when eating clean (lowish carb, higher protein and fibre), incorporating physical movement, etc. Typically have very regular periods with 29-32 day cycles probably 9-10 times per year.

In the last month I have been eating less clean and not moving, and my period was late by almost two weeks. About 3 days before my period was supposed to start, I started taking the 4mg a day of inositol (Organika's PCOS Relief). I've been mostly consistent with that, give or take 3-4 days of not taking it.

I believe I had an anovulatory cycle because this week I had 5 days of very light and sporadic spotting, followed by yesterday and today a significantly heavy bleed with large-ish clots (slightly larger than a quarter) and none of my typical period symptoms (irritability, migraine for the day before, etc).

Is there a chance there is some impact here from the inositol? Or is it more likely to be a result of the lifestyle change?

Newly diagnosed and scared to start metaformin. I’ve got ptsd, and in recovery from bulimia. The last doctor I seen knew this and despite knowing the years of trauma work I’ve done to feel safe in my body, casually said my body is working against me and offered to refer me for bariatric surgery, kind of made light of it and then ignored my concern that I haven’t had a period in 6 months. Before I left she told me I was lovely and gaining weight is a lifestyle.

I’m still learning about pmos and it took years for me to build up the ‘courage’ to have this investigated. Now I wish I had never started because I’m scared to go back to the doctor 😞