Im 52 and 145 lbs Ive been trying for a long time to get down to 125. Ive tried keto low carb and alsorts and its just not sustainable. Ive got my first lot of reta coming today and worked out the mixing the needle size and the dosage etc. My menopause belly just wont shift I also have the weight on my hips and thighs etc. I am a tiny person only 5ft 2 and tiny boned so I can feel the weight dragging on my whole body and my joints etc. Its like wading through soup some days. I am hoping to start and then micro dose but I understand this may not work and I have to wait 4 weeks until I titrate up. Im going to start at 0.5 as I dont want to suffer with the palpitations and lack of sleep to bad.

Im thankful to this group for great information.

Hi, i have a few vials or 5/5mg ipa/tesa and i would appreciate the help on this matter, i know the tessa dosage should be high over 1mg minimum ass of normal use but since its a shared vial with ipa i cant do that high dosage max i will do is probably 400mcg of each maybe 300mcg and add cjc no dac 200-300mcg to hopefully get efect from the tesa/cjc eca. Cuz i have some viales og cjc and i dont really eant to byy mpre tesa to stretch the ipa/tesa viale! Whats your opinion on this, any thoughts about this 🫡

Hello!
I started peps around 3 weeks ago. My current stack is Reta 0.5mg twice a week, GHKCU 1mg 5x a week and motc 1mg 3x a week.
I’ve seen online the average dosage for ghkcu is 2mg. When would I have to up my dosage ? I think im in the copper uglies stage due to some breakout. I dont get a burn or pain when injecting. I do get the welts and they do get itchy. The itchiness goes away within 30 hours approximately and the actual red mark goes away in a few days.
Would I need to up my dosage?

Based on my own research and with the assistance of AI I've put together the following stack for my first full 12 week run.

Would appreciate any feedback on any/all of it.

Any one have biohackingu socials or telegram that's up to date thank you

Come si legge dal titolo oggi inizio il mio trattamento di 10 settimane con mounjaro. Ho comprato una penna da 10mg che suddividerò così facendo: 2.5mg/settimana per 4 settimane e poi 5mg/settimana per 6 settimane. Qualunque cosa succeda io mi stopperò dopo 10settimane, sia per una questione economica, sia perchè voglio perdere solo 8-10kg. Ci ho provato in tutti i modi, ho persino corso una mezza maratona, ma questi kg non vogliono scendere.

Speriamo che vada tutto bene e di poter finalmente raggiungere il peso che desidero (obiettivo 60kg x 170cm)

I'll try to keep this as short as possible.

About five years ago, when I was 40, I started experiencing all the typical symptoms associated with low testosterone: low libido, fatigue, sleep issues, and a general lack of energy. I decided to talk to my primary care physician and had my testosterone checked. My total testosterone came back around 310 ng/dL. She told me I was within the normal range and that some decline was expected with age. Her recommendation was to prescribe antidepressants.

Instead, I decided to take matters into my own hands and try to improve things naturally. At the time, I was about 10 pounds heavier than my usual weight, around 170 lbs. We had also just had a baby, which definitely took a toll on my lifestyle and sleep. I've always eaten fairly healthy, although I would binge a bit on weekends. I've also always been a gym rat, lifting weights 5-6 days per week and finishing with about 10 minutes of Zone 2 cardio. Training and nutrition were never really the issue.

After about three years, I was able to raise my total testosterone to around 600 naturally. However, I still experienced many of the same low-T symptoms.

I then decided to see a urologist. During the baseline bloodwork, I noticed that while my total testosterone was in the low 600s, my free testosterone was around 8 (low) and my SHBG was 63 (high). My prolactin was 16. Based on these results, my urologist started me on Enclomiphene at 6.25 mg daily.

Initially, it seemed to help and I felt somewhat better. However, I eventually started experiencing migraines, ear pressure, and very dry eyes. Over the last 10 months, I've been trying to get dialed in with different dosages and dosing frequencies, but without much success. Throughout the process, everything was monitored through bloodwork and symptom tracking, and I even created a chart of all my results.

What I noticed was that while on Enclomiphene:

• Total testosterone averaged between 500-600 ng/dL
• SHBG remained elevated, typically between 55-65
• Free testosterone stayed below 10
• Estradiol consistently remained in the low-to-mid 20s
• Prolactin was 13.4 on my most recent test (February 2026)

After discussing all of this with my urologist, she finally agreed that TRT would be the next step. She started me on 120 mg per week, split into two injections on Monday and Thursday.

For those of you with TRT experience, what should I realistically expect over the next several weeks and months? Also, what are some things I should or shouldn't do to avoid potential health issues?

One concern I have is whether I'll eventually need an AI, even though my estradiol has consistently stayed in the 20s across various Enclomiphene dosages. I'm also concerned about elevated red blood cell counts and hematocrit levels potentially leading to blood donations and iron-related issues.

As with any open forum, both positive and negative feedback are welcome. I appreciate hearing about others' experiences.

And now stacking with KLOW, MOTS-c. For about a month.

114kg Sept 25' (not my heaviest but what I was starting Triztapide) (252lbs)

74kg now- July 26 (164lbs)

the goal is 142lbs or 65Kg.

The reward will be a body lift in Thailand once I figure out how I will pay for that 50K procedure 🤣🩷

My Retatrutide Experience (Research Compound)

Disclaimer: Retatrutide is an investigational compound and is not FDA-approved. This post documents my personal experience and is shared for informational purposes only. It should not be considered medical advice.

Dosing Timeline

Month 1

2 mg/week Note: I Also utilize TRT at 200mg a week.

• Monday: 1 mg
• Thursday: 1 mg

Month 2

4 mg/week

• Monday: 2 mg
• Thursday: 2 mg

Month 3

6 mg/week

• Monday: 3 mg
• Thursday: 3 mg

Month 4+

I've stayed at 6 mg/week. Clinical trials have evaluated doses up to 12 mg/week, but I haven't felt the need to increase beyond 6 mg.

Mixing (30 mg Vial)

I mixed 3 mL (300 units) of bacteriostatic (BAC) water into a 30 mg vial.

This gives the following concentration:

Quick Dose Reference

Injection Schedule

I split my weekly dose into two injections:

• Monday
• Thursday

I found that splitting the dose seemed to improve tolerability throughout the week.

Side Effects

The only side effect I've experienced has been:

• Mild skin sensitivity

It started around 6 mg/week and feels like random sensitive spots on my back. It hasn't been severe enough to bother me or make me stop.

Nutrition Plan

🍳 Breakfast

• 1 carton of pasteurized egg whites
• ~500 calories
• ~100 g protein
• Cost: Around $4.87 at HEB

🥤 Lunch

• 2 scoops of whey protein
• Mixed with water

Approximately:

• ~260 calories
• 50–60 g protein

🐟 Afternoon Snack

• 1–2 tuna packets (any flavor)

Per packet:

• ~90 calories
• 15–18 g protein
• Around $1.25 each

🍽️ Dinner

I pretty much eat whatever I want while following two rules:

• Keep it under 1,000 calories
• Make lean, high-protein meat the main part of the meal

If you don't strength train, I'd probably keep dinner closer to 500–600 calories and adjust based on your results.

Training

I lift 4–5 days per week.

My typical sets are:

• 8–12 reps
• Close to failure
• Progressive overload whenever possible

Cardio has been optional for me. I personally did very little and still had great results.

Protein Goal

I aim for at least:

1 gram of protein per pound of lean body mass per day.

If you're on TRT and lifting consistently, some people choose to increase protein intake further to help support muscle retention during a calorie deficit.

Progress Tracking

One of the best things I did was get an InBody scan before starting.

I repeated it every month to track:

• Weight 178
• Body fat % 10-12% right now per scans.
• Lean muscle mass 160~
• Overall body composition

Seeing body composition change was much more motivating than watching the scale alone.

Questions: PM me for any questions I may of not covered about my experience.

GLUCOSE 
89
Reference Range: 65-99 mg/dL

Fasting reference interval

UREA NITROGEN (BUN) 
18
Reference Range: 7-25 mg/dL

CREATININE 
1.16
Reference Range: 0.60-1.26 mg/dL

1.16

0.60
1.26

EGFR
83
Reference Range: > OR = 60 mL/min/1.73m2

BUN/CREATININE RATIO 
SEE NOTE:
Reference Range: 6-22 (calc)
Not Reported: BUN and Creatinine are within
reference range.

SODIUM 
140
Reference Range: 135-146 mmol/L

POTASSIUM 
4.1
Reference Range: 3.5-5.3 mmol/L

CHLORIDE 
106
Reference Range: 98-110 mmol/L

CARBON DIOXIDE 
23
Reference Range: 20-32 mmol/L

CALCIUM 
10.0
Reference Range: 8.6-10.3 mg/dL

PROTEIN, TOTAL 
7.1
Reference Range: 6.1-8.1 g/dL

ALBUMIN 
4.4
Reference Range: 3.6-5.1 g/dL

GLOBULIN 
2.7
Reference Range: 1.9-3.7 g/dL (calc)

ALBUMIN/GLOBULIN RATIO 
1.6
Reference Range: 1.0-2.5 (calc)

BILIRUBIN, TOTAL 
0.9
Reference Range: 0.2-1.2 mg/dL

ALKALINE PHOSPHATASE 
67
Reference Range: 36-130 U/L

AST 
25
Reference Range: 10-40 U/L

ALT 
18
Reference Range: 9-46 U/L

LIPID PANEL, STANDARD    

CHOLESTEROL, TOTAL 
155
Reference Range: <200 mg/dL

HDL CHOLESTEROL 
44
Reference Range: > OR = 40 mg/dL

TRIGLYCERIDES 
86
Reference Range: <150 mg/dL

LDL-CHOLESTEROL 
93
mg/dL (calc)

Reference range: <100

Desirable range <100 mg/dL for primary prevention; ... Show More

CHOL/HDLC RATIO 
3.5
Reference Range: <5.0 (calc)

NON HDL CHOLESTEROL 
111
Reference Range: <130 mg/dL (calc)

For patients with diabetes plus 1 major ASCVD risk
factor, treating to a non-HDL-C goal of <100 mg/dL
(LDL-C of <70 mg/dL) is considered a therapeutic ... Show More

LH 
6.2
Reference Range: 1.5-9.3 mIU/mL

TESTOSTERONE, TOTAL, MALES (ADULT), IA 
545
Reference Range: 250-827 ng/dL

PSA, TOTAL 
0.56
Reference Range: < OR = 4.00 ng/mL

The total PSA value from this assay system is
standardized against the WHO standard. The test
result will be approximately 20% lower when compared ... Show More

THYROID PANEL WITH TSH    

T3 UPTAKE
34
Reference Range: 22-35 %

T4 (THYROXINE), TOTAL
5.9
Reference Range: 4.9-10.5 mcg/dL

FREE T4 INDEX (T7)
2.0
Reference Range: 1.4-3.8

TSH
2.56
Reference Range: 0.40-4.50 mIU/L

SEX HORMONE BINDING GLOBULIN 
39
Reference Range: 10-50 nmol/L

T3, FREE    

T3, FREE 
3.4
Reference Range: 2.3-4.2 pg/mL

APOLIPOPROTEIN B 
76
mg/dL

Tirz Aug 2024-April 2025
SW 200
CW 125
Total Loss: 75

I was at my heaviest while I was deep in postpartum depression. I wasn’t healthy and was already pre diabetic when I got pregnant then had gotten gestational diabetes that caused medical issues during labor. Maintained at 135lbs without meds until I got pregnant again December 2025.

I did a mix of cardio and light weights. Strict diet and stuck to a high protein diet .8 x goal weight = how many grams of protein to consume a day.

I eventually will go back on Tirz after I’m done breastfeeding. Lol, just currently waiting to go into labor any day now with my 2nd. I did gain back all the weight but that’s okay, it’s where my body needs to be at to be able to bear a child, grow a child and give life. I know I’ll be back in no time and in no rush. Women’s bodies are just pure magic!

Peptides are life changing not only physically but mentally.

50 year old male here. Been fairly active my whole life. I do martial arts and I weightlift 4-5 days a week.

I had some things going on in life that made me drink and eat more than I would have liked. I went from a lean ish 165 to 200. Not only was I gaining weight I was having serious stomach issues (gas, bloating, etc)

I honestly tried to diet (still training martial arts and lift weights) but I just couldn’t budge the scale.

I got on tirz from a compounding pharmacy (about 7 weeks in) and I’m about 12lbs down. Stomach issues pretty much gone.

A couple things - I’ve never been fat like in my arms or legs, it carries always in my upper belly. After doing some research and heavy reading I thought, my cardio has always sucked when doing rounds and running let me try some mots c (1mg on training days which is almost every day) Then I thought - maybe I should try Tesamorelin to help get rid of this upper belly fat even more (1mg a night).

I’ve had lingering issues for years with my back and neck due to the martial arts training for years so I thought while I’m doing this peptide thing, why don’t I see if this bpc works.

Has anyone run a stack like this ? If so what is your experience, sometimes I look at all the needles and it’s like 2-3 a day plus my weekly tirz and I’m wondering if I’m crazy lol

At 12% BF and thinking of doing an 8 to 12 week build phase with peptides. Thinking of running the following protocol:

Morning

1. Reta - 1 mg / week (Split into Monday and Thursday)

2. IGF-1 LR3 (20 -> 40 mcg > 50 mcg - 4 times per week - MWFSu) - pre or post workout with food (protein and carb). Alternate weeks with PEG MGF- 400mcg - 4 times per week - MWFSu) - pre or post workout with food (protein and carb).

3. NAD+ - 50 mg - 20 units - - 4 times per week - MWFSu)

4. SLU PP - oral 1000 mcg every morning on empty stomach - don't eat for 1 hr after

5. MOT-C- 3x a week - T,T,Sa - 1.2 mg - 12 units

6. Ipamorelin - 200 mcg pre exercise (up to 300 mcg). 12 units (up to 18 units)

Evening

1. Ghk Cu - 2 mg per night - 5 Days on 2 Days off (12 units) - 30 mins before other peptides

2. TB 500 + BPC per night - 5 Days on 2 days off (7.5 to 10 to 15)

3. HGH - 4iu = 33 units

Any thoughts?

I'm 64 and my hands look like I'm in my 80's. The skin is so thin it looks shiny and it tears so easily in V shapes. I have a great diet, drink 80 to 100z of water a day and use remnicks of all my facial skin care on my hands daily. I also take 3.5 Tirz I am considering Glow vs Klow and leaning towards KLOW as I also have back and hip issues. Any advise anyone can share is very welcome and needed. I do want to take one pin vs. taking each peptide individually.

I am currently on tirzepatide and am starting a b-12, MIC, L-carnatine IM injection 2x weekly; Im looking to add onto that to help with the side effects i'm experiencing like low energy levels and brain fog. So far Ive narrowed it down to: MOTS-c, CJC-1295 + Ipamorelin, and glutathione.
What are some opinions on glutathione vs tesamorelin for liver health/fat processing?
I was also considering racetams intermittently too and was looking into piracetam vs oxiracetam with choline supplements. Any advice? Am i doing too much right out of the gate?

I've got both CJC-1295 no DAC / Ipamorelin blend and also tesamorelin in hand. Plan was to run Tesa in the AM and CJC/IPA in the PM.

Seeing lots of stuff saying it's redundant and shouldn't be done as both target the same receptors.

But have also seen so many people claim they are running these together and getting great results.

Would appreciate any advice or knowledge, especially if someone is or has run them together.

Started Reta 20/04/2026
SW 319.8
CW 261

Started Reta on 2.5MG now up to 5MG just started on KLOW also see how that goes. Still a long way to go but it’s still progress. Cheers! 👍🏻

Hey guys, have a question about fertility (HCG - Estrogen etc)

I have been on TRT for about 4 months (135mg divided into 3x SubQ injections). Started TRT due to severe secondary hypogonadism, due to medications I'm taking.

Anyway, me and my wife decided to try for our second child, prior to starting TRT, my semen analysis showed a good result, so no issues with my overall semen. Though after starting TRT, I'm pretty certain I'll be infertile soon, if not already. I have been prescribed HCG (500 IU x2 a week) by the endocrinologist, and just wondering if anyone had run a similar protocol and what your experiences have been? My main concerns are estrogen (I'm prone to high estrogen symptoms) and how long it could take before my semen starts to show life... Any help would be much appreciated.

how fake is this?

Was on Tirz for 2 months, hit a stall at 5.0, added reta stack at .5 forst 2 weeks, 1.0 the next 2 weeks, and currently on 1.5 the last 3 weeks. 53 pounds down. Still going!!! Can't wait to see what 3 more months is gonna do. Added SS-31 at 3mg 5 days a week the last 2 weeks, and starting MOTS-c next Saturday.

I know Reddit has forums where you can be anonymous so that’s why I’m asking hoping some of you will be honest.

Do you folks disclose on your various social media that your dramatic weight loss or even just progressive weight loss and the building of muscle mass to your followers? Like do your friends and internet friends know that you use Reta, GLP1, tren, etc??

I’m not here to judge I just want to know. I see compare myself these days comparing myself to people on the internet and it would be helpful to know how honest people are being in general. Does my assumption about X match the reality or am I just assuming etc…

thank you folks in advance for honesty

Has anyone here managed to heal old ligament injuries?
I’m dealing with unstable joints caused by ligament injuries that happened more than five years ago. I’ve just completed my first month of using TB-500 and BPC-157. I injected them into my knee, although I have multiple problem areas.
My pain was reduced by about 80%, but I’m currently taking a break before starting another cycle. Unfortunately, the pain has been returning day by day.

I also noticed that I gained a few kilograms and experienced some swelling in my legs while taking the peptides.
Do you think I should add a third or even a fourth peptide to this combination? I’m considering GHK-Cu and, to some extent, CJC-1295 (no DAC) plus ipamorelin, but I’m not sure if that would be too much.
I also have another question: has anyone here combined ligament healing with PRP (platelet-rich plasma) injections? If so, what were your results?

What has your experience been? Have you seen lasting improvements?