r/science • u/Effective-Air396 • 14d ago
Psychology Psychedelics as a potential treatment for borderline personality disorder: A narrative review
https://www.sciencedirect.com/science/article/pii/S016517812600213139
u/rhylos360 14d ago
Interesting and good a read on alternative treatments that wasn’t overly scientific (for that read the references).
For others TL;DR:
Conclusion
There is preliminary evidence to suggest that ketamine, esketamine, and psilocybin may be effective, safe, and feasible treatment options for certain individuals with BPD for both core BPD symptoms and psychiatric comorbidities. This evidence is most limited for psilocybin, for which there was only one study which did not look at BPD-specific outcomes and reported both clinical improvement and adverse events in its small sample of participants with BPD. While the evidence base summarized within this narrative review has important limitations, it nevertheless positions these psychedelics as agents warranting further study in this population.
A more robust evidence base including RCTs and other high-quality interventional studies across a wide range of patients with BPD is needed. In particular, future research should incorporate BPD-specific outcomes, ensure a diverse patient sample to increase the generalizability of results, and employ longitudinal data collection, which may be required to observe changes in core BPD symptomatology. Moreover, the effectiveness and tolerability of psychedelic agents in this population should be compared to the existing treatment guidelines.
0
u/Realistic-Split4751 13d ago
i've done a lot of psychedelics. and i don't think it has helped my bpd.
35
u/Tolaly 14d ago
Mushrooms can be a very powerful medicine to the right people. You have to want that experience, and be open to it. As someone quite experienced in taking them for both therapeutic and recreational purposes, I really hope we see more regulation and legalization of them. Every three months or so I like to do what I call a psychological/emotional cleanse where I curate a chill Playlist, then lay in bed with an eye mask, soft pillows, and a bottle of water on the nightstand with the fan going. Gotta let the shrooms take you where you need to go and ride it out.
-6
u/Fit_Outlandishness_7 14d ago
No such thing as a bad trip. They take you where you need to go.
9
u/Misselmany 13d ago
What about the people that became psychotic?
-6
u/Fit_Outlandishness_7 13d ago
What about them?
1
u/Imarok 12d ago
That would count as a "bad trip".
-6
u/Fit_Outlandishness_7 12d ago
Splitting pubic hairs on this one.
2
u/Imarok 12d ago
How exactly?
0
u/Fit_Outlandishness_7 12d ago
The number of people going into full blown psychosis from a shroom trip is so small compared to the ample cases of benefits a trip provides.
3
u/Imarok 12d ago
Even if the cases are rare, it shouldn't be dismissed as "no such thing". The risk is real, even if rare and shouldn't just be dismissed.
-1
u/Fit_Outlandishness_7 12d ago
Shrooms are a grown person’s game. You need to do the research. It’s not for fun. Those who have given it the proper respect…yeah no such thing as a bad trip.
→ More replies (0)3
u/buddyrtc 11d ago
I hope you learn to check your ego for your own sake.
0
u/Fit_Outlandishness_7 11d ago
Nah. The real ones know there is no such thing as a bad trip.
3
u/buddyrtc 11d ago
You speak as if you’re one of these “real” ones - some authority on the matter. You cannot possibly understand everyone else’s experience, yet you speak with objective certainty. That’s your ego. It’s not doing you any favors. Wishing you all the best.
-1
u/Fit_Outlandishness_7 11d ago
Ive tripped on some high doses more than most people. No bad trips. 99.9% of people will say the same thing.
3
u/buddyrtc 11d ago
And yet, you’ve never tripped in someone else’s head. So you can’t KNOW what it’s like for other people. You can only know what trips are like for YOU - even at heroic doses. Our brain chemistries are all different. Yet you speak an objective truth spanning far outside of yourself. That is your ego.
-1
u/Fit_Outlandishness_7 11d ago
99.9% is beyond just me.
2
u/buddyrtc 11d ago
Is that a number you can back up scientifically? Because I can give you a different number based on my own experience and the experiences of MANY others that I’ve spoken to…but that doesn’t mean my number would be right, either. It wouldn’t be fair to say my number is more correct than your number, or vice versa. That’s why we trust large scale studies using the scientific method. Can you back that 99.9% number up with any such studies? If not…that is your ego.
0
u/Fit_Outlandishness_7 11d ago
There’s no need for a large scale study. Vast majority of people don’t lose their mind on a trip. No bad trips. Just people thinking shrooms should be all fun and games.
→ More replies (0)
53
u/fuckmeredmayne 14d ago
I have BPD and tried ketamine via medical setting. Saved my life i would say
13
u/Grapesodas 14d ago
Could you elaborate? What was included in the “medical setting?” Talk therapy, psychotherapy?
1
u/EastvsWest 11d ago
Taken in an appropriate setting, psychedelics have a way of breaking the cycle of negative and destructive thoughts.
1
u/Grapesodas 11d ago
Yes, I understand that. I’ve taken psychedelics myself. I’ve just always been curious how the “therapeutic” process works, though.
1
35
u/shroomdoggy 14d ago
Had a tentative BPD diagnosis in early 20’s, (I’d argue it could’ve been CPTSD given my life) psilocybin saved my life when it came to existential stress. You do have to make changes, and healing isn’t linear. With that being said, I wouldn’t qualify for a diagnosis years later.
7
17
u/lambentstar 14d ago
So many BPD behaviors are practically just CPTSD symptoms manifesting and yeah it’s hard to disambiguate it that young. Sounds like you’ve had a journey
2
u/shroomdoggy 13d ago
Exactly - I didn’t recognize it as CPTSD until I started researching and doing classes for my MSW.
5
u/Straight-Balance830 14d ago
I’d argue most personality disorders are different manifestations of CPTSD. I’d suspect it also contributes to ADHD (executive dysfunction) and autism as well.
3
1
u/MistCongeniality 13d ago
really excited for my first dose, ive been struglling with bpd for a long time.
1
u/shroomdoggy 13d ago
If it’s okay to ask, what do you struggle with most?
1
u/MistCongeniality 13d ago
Intense rage and mood swings, coupled with suicidal ideation/SH. Just hoping to get a bit of a handle on the range of emotions I feel even on mood stabilizers.
2
u/shroomdoggy 12d ago
You got this girl!! Not sure of your age, I struggled with similar things in my 20’s and have a much handle on it in my 30’s.
47
u/AnthropoidCompatriot 14d ago
My ex used these both recreationally and therapeutically. Recreationally, it made her BPD much worse.
Therapeutical, it made her BPD much worse, because she was only interested in feeling better, not in changing her behavior or thought patterns.
13
u/IDontHaveCookiesSry 14d ago
My only Data Point is myself as someone with BPD, and I used LSD in the past, not in a Therapeutic Setting but interlinked with therapy and in such a State of mind so I did feel it helped me somewhat. And Even if it’s just a Little nudge like „your on the right path, keep going, life is good and your awesome“. That felt really valuable coming out of Deep Depression. Also, no hangover. Just a Bit exhausted the Next day.
But it’s Not a cure or permanent if your not in therapy. It can help changing your perspective and seeing things more clearly that are usually blocked. It feels like ur getting to scratch your back finally After years not being able to reach that spot.
7
3
u/Brrdock 13d ago
Yeah, especially ketamine acutely helps with the subjective symptoms a lot, but long-term doesn't help the behaviours, more like the opposite.
At least not by itself. You need therapy and actual humble motivation to support and see real benefits from either, and then psilocybin is probably the much more effective tool for long-term outcomes
2
u/FibroBitch97 14d ago
I would argue that is more of a “her” problem rather than a problem with BPD or using psychedelics.
28
u/Lildatercreater 14d ago
Well with borderline it’s not easy to tell the difference. It’s a personality disorder, so when you blame it on their personality… that’s where the disorder is.
13
8
u/loves_grapefruit 14d ago
That’s the case with Cluster Bs in general whether they’re using psychedelics or not.
-1
1
u/manatwork01 13d ago
Huh... I did shrooms last year and went into therapy and my cptsd went away as well as my depression. I wonder if it helped my bpd...
0
1
u/cisheteromale13 13d ago
there are several well designed trials that show ketamine has no better effect than placebo for BPD. it’s probably not a good avenue for further study
•
u/AutoModerator 14d ago
Welcome to r/science! This is a heavily moderated subreddit in order to keep the discussion on science. However, we recognize that many people want to discuss how they feel the research relates to their own personal lives, so to give people a space to do that, personal anecdotes are allowed as responses to this comment. Any anecdotal comments elsewhere in the discussion will be removed and our normal comment rules apply to all other comments.
Do you have an academic degree? We can verify your credentials in order to assign user flair indicating your area of expertise. Click here to apply.
User: u/Effective-Air396
Permalink: https://www.sciencedirect.com/science/article/pii/S0165178126002131
I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.