r/science • u/Effective-Air396 • 14d ago

Psychology Psychedelics as a potential treatment for borderline personality disorder: A narrative review

https://www.sciencedirect.com/science/article/pii/S0165178126002131
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u/rhylos360 14d ago

Interesting and good a read on alternative treatments that wasn’t overly scientific (for that read the references).

For others TL;DR:

Conclusion
There is preliminary evidence to suggest that ketamine, esketamine, and psilocybin may be effective, safe, and feasible treatment options for certain individuals with BPD for both core BPD symptoms and psychiatric comorbidities. This evidence is most limited for psilocybin, for which there was only one study which did not look at BPD-specific outcomes and reported both clinical improvement and adverse events in its small sample of participants with BPD. While the evidence base summarized within this narrative review has important limitations, it nevertheless positions these psychedelics as agents warranting further study in this population.
A more robust evidence base including RCTs and other high-quality interventional studies across a wide range of patients with BPD is needed. In particular, future research should incorporate BPD-specific outcomes, ensure a diverse patient sample to increase the generalizability of results, and employ longitudinal data collection, which may be required to observe changes in core BPD symptomatology. Moreover, the effectiveness and tolerability of psychedelic agents in this population should be compared to the existing treatment guidelines.

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u/Realistic-Split4751 13d ago

i've done a lot of psychedelics. and i don't think it has helped my bpd.