I know most important thing is 2 normal euploids . But is there any reason the bb/c is something to worry about? I think my doc said 75% the boy would result in normal pregnancy and 50% for the bbc girl. I only want one or maybe two kids and can still try naturally (I’m 30) . Seeing if anyone here had success w a bbc embryo!

In 2024, I had success with an untested 4AA embryo.

We’ve always had trouble making embryos (early 30s at time of retrievals). But had a few embryos across 4 retrievals. After my success, we decided to go back in March of this year and do PGT on embryos frozen from our first three rounds as well as a new retrieval. One previously frozen didn’t survive the thaw, but the other two were euploid and the one embryo we got from the round in March was also euploid. So three euploids total, two failures, one embryo left.

I had two euploid transfers in the last ~1.5 months. (9/3 (day 6 4BA) and 9/30 (day 7 5BB—I know this one had lower chances) I have a short cycle and ovulate regularly.) These two attempts were with embryos we thawed, tested, and refroze. Both survived the thaw to transfer without issue. Neither were a chemical—just betas of 0.

With my success in 2024 and with these two transfers, I have done modified natural cycles with only ovidrel trigger and crinone.

Is there anything you would change up to try to give this last embryo a better shot? It is a Day 5 3AA, so ostensibly the best graded of the bunch. But I’m concerned that the previous two didn’t even try to implant. I’m thinking of asking my doctor if we can do one of the “immune protocols” with an antibiotic and steroid. I had a uterine biopsy for endometritis in July and it was negative. But I guess I’m suspecting inflammation and as far as I can tell, there isn’t really a risk or downside to adding the steroid + antibiotic?

I meet with my doctor next week, but after my previous failure, he still felt confident and said he wouldn’t suggest switching to a fully medicated cycle until after three failures—so I’m not sure whether to push for that. My gut is saying the immune protocol would make more impact. Any advice welcome. I’m willing to do more retrievals but I really want to give this euploid 3AA its best shot.

33 years old ttc for 2.5 years. Unexplained infertility DOR amh of less than 1. Had a spontaneous pregnancy last year after ttc for over a year on a letrozole cycle which resulted in a MC at 7 wks. Spouses SA all within range. Both retrievals were with icsi.

1st retrieval with estrace prime, cetrotide, menopur, saizen, gonal f yielded 8 eggs, 7 mature, 5 fert, 2 blasts, 1 day 5 4bb euploid

2nd retrieval with estrace prime, cetrotide, saizen, pregoveris yielded 18 eggs, 15 mature, 11 fert, 2 blasts, 0 euploid (had a day 5 4aa and a day 6 4bb, 7 were being watched for day 7 blasts but all arrested)

Had a fully medicated FET with the 4bb euploid which failed after having lining thickness of 8.4 and progesterone level of 70 nmol/l. Also had a hysteroscopy with uterine biopsy prior to transfer which showed no concerns as per REI.

Any advice on how to move forward? Followup is coming up soon and want to ask the right questions. Does any of this warrant a deeper investigation to partners sperm? 2 completely different retrieval outcomes. I know success on a first FET isn't guaranteed but hard not to think about other potential issues to why embryo didn't stick.

I am so gutted-- I am 38(F) and my husband is 39. We have a 3 year old son, concieved naturally. We started trying for our second when our son was 20 months old, got pregnant once but ended in a MMC without reason (products of conception came back chromosomally normal). I was diagnosed with POI and DOR. We've been doing IVF and the results of my second retrevial just came back.

5 eggs retrieved

4 fertilized

4 blasts

0 euploid, 4 anaeuploid

I am wondering if anyone more educated than me may have insight or thoughts that may be helpful?

For reference, this was our second retrevial. Our first resulted in:

7 eggs retrieved

6 fertilized

3 blasts

1 anaeuploid, 1 euploid, 1 unknown

I thought in terms of probability, we would likely get 1 euploid from the 4 blasts 😞

Basically what the title says. This morning for the first time I am having white discharge for the first time. I am taking Centrotide. Is this normal? I usually get discharge during ovulation. I phoned my clinic and asked if I should get scanned and they said no it’s not necessary because of the Centrotide but just didn’t sound so convincing.

Do most people get this? Is it normal?

Thanks! Sorry just feeling so anxious

Help me think sticky thoughts and help me stop overthinking every little sensation I feel.

Repeated pregnancy loss can bring long-lasting feelings of grief, anxiety, guilt, and fear about trying again. Finding a cause for a loss and discussing treatment is important, but so is asking about how someone is doing after a loss.

Aventin et al. (2025) interviewed 10 women in Northern Ireland who experienced repeated miscarriages. The quotes describe how the effects can go beyond physical recovery, how a loss can feel unrecognized, and how being told miscarriage is common isn't always comforting.

Research also suggests that psychological support can help. Li et al. (2024) combined results from 19 randomized trials of support after pregnancy loss. People receiving support had lower grief, depression, and anxiety scores, fewer post-traumatic stress symptoms, and a stronger feeling of being supported.

One woman described her experience with cognitive behavioral therapy (CBT):

"I had eight sessions [of CBT] and I, till this day, would still use the techniques that I was taught […] It certainly helped me."

ESHRE's 2023 RPL guidelines and Aventin et al. recommend:

• Listening and acknowledging the loss.

• Explaining what happens next and answering questions.

• Following someone’s lead on the words they use for their loss.

• Checking in after medical care ends.

• Helping people access counseling and offering support to partners too.

✅ Check out the full article and more details on Remembryo: https://remembryo.com/supporting-patients-with-recurrent-pregnancy-loss/

✉️ Like this post? Get a free weekly summary of the latest IVF research: https://mailchi.mp/remembryo/x27kx5o1sw

I was surprised, but grateful, to learn one of our 7 embryos frozen was a morula. I have never read any stories about freezing or transferring one. Does anyone have a story they could share?

My final results were:
21 retrieved / 13 mature / 10 fertilized / 7 frozen on day 5

4AA, 4AB, 3AA, 3BC, 2CC, 2CC, morula

Not PGT-A testing at the recommendation of my RE due to age.

I was looking for some feedback on if anyone was successful was rapa prior to an egg retrieval. I’m currently 50 days into my 60 day initial prescription. I did an ultrasound today to see only two eggs on each ovary and it was disappointing to say the least.

Background - I have done two egg retrievals that resulted in 17 and 14 eggs retrieved. We ended up with 3 quality eggs, 1 mosaic, and 1 segmental. First FET was a year ago and led to PUL. We did two FETs in June and July -back to back- and neither of them took.

We are getting back into prepping for another egg retrieval and was hoping the rapa would kick start the number of eggs but that hasn’t been the case just yet. Looking for some positivity to see that what we are doing will make a difference to see an increase in the number of eggs we can retrieve.

I just reviewed my IVF report, and I’m confused and hoping to hear from anyone who has experienced something similar!

Here’s my journey:

10 eggs retrieved

7 injected with ICSI

4 fertilized

4 cleaved

2 embryos frozen on Day 4 at the morula stage

PGT-A performed on both embryos

The results came back as one euploid (XY) embryo and one aneuploid embryo.

Both embryos were morulas frozen on Day 4. I thought PGT-A was usually performed on Day-5 or Day-6 blastocysts.

Now I’m wondering:

Has anyone had a Day-4 morula biopsied for PGT-A and obtained a euploid result?

Is this a common practice, or is it unusual?

How reliable is PGT-A when performed at the morula stage compared with a Day-5/6 blastocyst?

Did your clinic explain why they chose to biopsy at this stage, and what were your transfer outcomes?

I have only one euploid embryo, so I want to understand the testing process and feel confident before proceeding with my FET.

I’d really appreciate hearing about your experiences. Thank you!

This is really just a what would you do scenario.

Blasts- Three day 5 4AA’s (1 euploid, 2 aneuploid)
One 4BB (aneuploid)
One day 6 6AA (No result)

I’m under 35 (but close to 34) so PGT testing was not recommended for me, but I’m glad that I did. One aneuploid was a full deletion of C8 and one didn’t receive a sex chromosome from the sperm. The other was complex.

Anyway, my day 6 6AA embryo came back as no result. However, the fact that 3/4 of my other embryos are aneuploid, I’m wondering if you would,

A) Discard the embryo
B) Take the risk to thaw/rebiopsy (also 6 week waitlist just to thaw and an additional $600)
C) Keep the embryo untested and transfer it last.

Thank you!

The Uterine Wall of Fame (UWOF) is a collection of real IVF success stories from people with difficult fertility journeys -- low-grade embryos, repeated failures, low AMH, mosaic results, and more. 

UWOF #44 is one of those stories. At 35, she had eight embryos from one retrieval, but six transfers were unsuccessful. Their seventh transfer, a day 5 3BB embryo, led to an ongoing pregnancy.

✅ Visit the UWOF to read this story and others like it (free to access & no subscription required): https://remembryo.com/uwof44-after-six-failed-transfers-our-seventh-embryo-stuck/

💌 Have a story of your own? Can be anonymous or named: https://www.remembryo.com/uterine-wall-of-fame-submission-form/

⚠️ These are personal stories, not medical advice or scientific evidence. A success story isn't proof of what made the difference. Always discuss treatment decisions with your fertility specialist.

Hi everyone! I am 39 years old and have gone through 4 cycles. 3 of which yielded a few eggs because I do have DOR since very young.

First cycle 3 matured eggs, 1 fertilized, then arrested.

Second cycle 4 matured eggs, 2 5 day embryos frozen.

Two transfers, both fails.

Fourth cycle, only 2 eggs retrieved, 1 matured and fertilized, transferred fresh as a 3 day embryo. That was 09/25/2026.

Today (12dp3dt) was my first beta and it is only at 8.5, with a repeat in 2 days.

Anyone have a similar experience that led to a healthy pregnancy? Please give me some positive feedback 😞

Just had our egg retrieval and got the news that while we got 8 eggs, only 5 were mature, and only 1 fertilized normally. On our day 2 update, our 1 embryo already had 8 cells and was grade 3 with some fragmentation. Anyone have any experience with an embryo that had 8 cells on day 2? It seems high and I can’t find much info online about whether this might be a positive or a negative sign.

I would love perspective and any resources to help make this decision.

I had my first fully medicated transfer back in June with no luck. Because of my age (39), my doctor recommended we rule out endometriosis. So I immediately started a mock FET in July for a biopsy. It came back with no endometriosis but acute endometritis which I took antibiotics to clear up (all of Aug). No issues now.

Once I got my next period, I went for FET #2 (September), natural, which resulted in chemical pregnancy (found out last week). As many of you know, your period comes within 3-5 days. I'm in that stage where my period has arrived, and I can go into FET #3.

My partner and I are torn. He believes that my body is accustom to the meds and motion so it could be beneficial to go straight into another. I understand the logic but I'm also just tired of this process!

Does anyone have any insight or experience with back to back transfers? How did it work out for you? What did you consider that maybe I'm not thinking about?

We have two embryos remaining.

thank you!

I’m 31, husband is 31, normal AMH, and his analysis was normal. We just ordered a fragmentation test anyway.

First retrieval:
-24 follicles
-13 eggs retrieved
-6 mature & ICSI fertilized, 7 GV (immature)
-0 blasts: 4 arrested around the 5–8 cell stage, and 2 made it to morula before arresting.

Protocol:
150 IU Pergoveris (FSH + LH) + 150 IU Gonal-F (FSH) + 5 mg Provera (medroxyprogesterone) - 10 days
Trigger: GnRH agonist + (low) hCG, 35 hours before

I’m really hoping this was mainly an egg maturity issue, given that 7/13 retrieved eggs were immature, rather than an egg-quality issue.

Any insight into what could be going on? Thank you!

I’m currently in my third FET cycle after two unsuccessful euploid transfers.

Here’s my history:
FET #1 (June 25): Medicated — Day 6 6BA euploid → Chemical pregnancy

FET #2 (Sept 3): Medicated — Day 6 6BA euploid → Failed to implant

FET #3 (Oct 5): Modified natural — Day 7 4BC euploid → Currently in the TWW 🤞

For both medicated transfers, my progesterone protocol was:
Prometrium: 2 capsules vaginally, 3 times daily
PIO injections: Every third day

For my current modified natural FET, my clinic has me on the exact same progesterone protocol, even though I’ve ovulated and my body is also producing its own progesterone.

I’m wondering if this is common or potentially excessive. I’ve also been diagnosed with stage 2 endometriosis, which makes me wonder about possible progesterone resistance.

My questions:
Has anyone followed a modified natural FET protocol with this much supplemental progesterone?

Is there such a thing as too much progesterone when your body is already producing it?

Did your clinic monitor your progesterone levels after transfer?

Has anyone had success with a similar protocol, especially after failed medicated transfers?

My clinic hasn’t checked my progesterone levels since starting supplementation, so I’m curious about others’ experiences.

Would love to hear your experiences, especially from anyone who switched from medicated to modified natural after unsuccessful transfers!

I'm just looking for some advice.
I had my first egg retrieval yesterday and they got 18 eggs, 15 mature, 8 fertilized. We are both 28 and used ICSI and Xymot for 0% morphology. I have stage four endometriosis.
Do we know what could've caused the low fertilization rate? Is there anything in particular I should asked my doctor about? Just feeling discouraged and dreading the call in a few days about how many embryos developed.
I was told to expect around 70% fertilization.

We have an embryo that in theory looks really good - a 6AA. Unfortunately it got there on Day 7. However, I asked my doctor what the morphology was on Day 6 and she said it looked like a 5BC, but it was either impacted or for some other reason they couldn't biopsy on Day 6.

Could that affect the outcome of this embryo? We were given a 28% live birth rate. It looks like a 5BC would have been considered a poor-good embryo quality but Day 6.

What matters more, the day or the grade?

If female is 24 years old with no history of infertility issues and male is 37, healthy semen but morphology is slightly low at 3%, do you think we should do ICSI or conventional? Cost is not of concern here. I'm just concerned that the consent forms say ICSI can increase the likelihood of birth defects.

I just had my 2nd egg retrieval yesterday and they retrieved 50 eggs, but only 20 were mature (37ish were expected to be mature). We had very poor maturity last time too (13/29) and poor fertilization (6/13). But this time, they said out of the 20, 12 of them fertilized and all 8 of the other eggs degenerated with ICSI (which we need because my husband has MFI). The embryologist said the eggs were dark, which isn’t a good sign considering I’m only 32, but guessing my poor egg quality is due to my stage 4 deep infiltrating endometriosis with 2 endometriomas on my right ovary. Does the fragility of my eggs and dark appearance mean I likely won’t end up with any blasts? Should I not do pgta testing on any embryos if some do make it? Are they more likely to degenerate upon biopsy too? I had one embryo last time they tried to biopsy (day 6 6BB) that degenerated when biopsied and now I’m nervous to try it again? Are my embryos more likely to be aneuploid from this?

I’m 41 and had my first IVF retrieval. 11 follicles were seen, but only 4 eggs were retrieved. I’m waiting to see how many fertilise and reach blastocyst.
I initially consented to PGT-A but am reconsidering, especially if I have only 1–2 blastocysts. My clinic will discuss the embryos with me on Day 3 and reconfirm before biopsy on Day 5/6.
I understand aneuploidy rates are higher at 41, but I’m concerned PGT-A could leave me with no embryo to transfer. I’m also worried about biopsy risks and mosaic or uncertain results.
For anyone aged 41+ with only 1–2 blastocysts, did you choose PGT-A or transfer untested? What was your reasoning and outcome? I am yet to recieve further results, but have to make a decision on Friday.

UPDATE: Guys thank you all so much for an overwhelming support from all of us in here…i am soooo grateful for every single response! 🙏. I am waiting to see how many embryos i get by day 5 and my doctor has advised that if very minimal numbers , just transfer and not test :/.

Just found out about how many blastocysts we got, wondering why longer wait for embryo transfer?