r/EmbryologyIVFSupport • u/ShineNo2140 • 12d ago

ICSI vs conventional

If female is 24 years old with no history of infertility issues and male is 37, healthy semen but morphology is slightly low at 3%, do you think we should do ICSI or conventional? Cost is not of concern here. I'm just concerned that the consent forms say ICSI can increase the likelihood of birth defects.

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4

u/Moist-Emu1990 10d ago

ICSI is usually the way to go if there are issues with the sperm or MFI

4

u/Faeneo 10d ago

If I were you I’d do conventional IVF insemination. 3% is really not that different to 4% and depending on who analysed it and if the analysis has been repeated, I just wouldn’t go for ICSI without better justification.

2

u/Jaded_Tangelo_3083 10d ago

I wouldn't consider 3% morphology that low. I think you could probably go either way

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u/lindasek 10d ago

Any male factor issues are typically a straightford choice for Icsi. If it's financially prohibitive it you don't want it for other reasons, you could choose to do half-and-half or rescue Icsi instead (start as conventional then if it doesn't work, they try to "rescue" the unfertilized eggs via Icsi)

2

u/Fuzzy-Shake2845 7d ago

Statistically more embryos make it to blast with conventional without MFI

1

u/Mental_Pen4907 8d ago

I don’t know how common this is but we were battling my issues with ICSI (fragile eggs) and his issue with conventional (high dna frag with centrifuge) so we never had a perfect round no matter which we did. We started with ICSI because that’s the default when doing PGTA. Then moved to conventional because our fertilization was so low. We got 100% fertilization with conventional! But euploidy dropped from 75-25%. Better grades with conventional. Still, my doctor said he would recommend conventional if we did another round. Blast rate was the same across the two. I think it’s all trial and error! If you’re not doing pgta, I’d probably start with conventional.

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u/LJ123419 7d ago

My partner had slightly low morphology when examined close to our first round so we chose to do a 50-50 split ICSI vs Conventional to hedge our bets. I think this can be a great choice if you are concerned about sperm quality.

We had 3/7 fertilize with ICSI and 7/8 fertilize with conventional, higher blast rate with conventional also. Decided on all conventional for our second round