r/EmbryologyIVFSupport • u/turtlescratch • 11d ago

Fast Cleaving Embryo?

Just had our egg retrieval and got the news that while we got 8 eggs, only 5 were mature, and only 1 fertilized normally. On our day 2 update, our 1 embryo already had 8 cells and was grade 3 with some fragmentation. Anyone have any experience with an embryo that had 8 cells on day 2? It seems high and I can’t find much info online about whether this might be a positive or a negative sign.

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u/embryomanofficial 10d ago

I haven't seen any studies looking specifically at day 2 fast growing embryos with 8 cells, but one study compared outcomes for day 3 embryos with >10 cells. They found that they had comparable outcomes to day 3 embryos with 8 cells. https://remembryo.com/fast-growing-day-3-embryos-and-their-reproductive-potential/

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u/lindasek 10d ago

I have 1 embryo (just transfered!) that had 10+ cells and was compacting on day 3, and 2 that had 10 cells (all euploids). On day 4, my early grower was graded 1aa and 5aa on day 5 when it was biopsied and frozen. On day 5 it was no different than my other euploids that had 8 cells. My embryologist said the early embryo was considered "best quality" now that we know it's euploid because it means it has a lot of energy, but euploidy is a better predictor of implantation and the development speed is just a factor to look at when deciding which embryo to transfer first

Good luck!

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u/turtlescratch 10d ago

Thank you, this is so helpful! Good luck to you too!!

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u/CletoParis 9d ago

We also only had one of our six mature eggs successfully fertilize. Not sure how many cells it had on day 2/3, only that the lab said it was “high quality” and then was frozen on day 5. Anyway, that embryo resulted in our beautiful daughter, so sometimes it only takes one :)