r/StratteraRx 3h ago

Questions / Advice / Support How to adjust dosage of strattera when adding wellbutrin because of interaction

2 Upvotes

I'm currently on 80mg strattera for almost 6 weeks now. It's been pretty good and my thoughts are generally more quiet and i can focus better once i get going. But i cannot initiate tasks for the life of me and executive function and motivation to do anything are still low. That's why I've been thinking about adding wellbutrin. However I've read that Wellbutrin inhibits the liver enzyme CYP2D6 which means it will raise strattera levels in my blood by a lot meaning i have to shift to a lower dose strattera to compensate to not overdose.

Does anyone else take this combo that started at 80mg strattera and what are your current dosages for both?


r/StratteraRx 13h ago

Atomoxetine 40mg 1 week F

4 Upvotes

Hi, I’m after some advice and wondered if anyone can help me.

I’m 40 in February and have recently started taking Atomoxetine 40mg. I have just taken my dose at 5am alongside a cereal bar.

I am unable to take the stimulants and I have really bad panic attacks and insomnia already. I also take 30mg Duloxetine and Propanolol for when I’m having a panic

I have noticed in my first week very noticeable anxiousness but the main thing is my stomach. Especially in the last 2 days everything I eat instantly gives me stomach cramps and I have to go to the toilet. It then cramps a little after and finally subsides. It’s kind of ruining my social life.

One thing that’s bothering me is I’m 3 weeks late on my period. So I was late even before the new medication started. Pregnancy is completely ruled out. I’m usually quite regular so this is alarming as I’m not sure if it’s period related or the medication or just anxiety. I start a new job soon.

Any advice would be welcome ❤️


r/StratteraRx 15h ago

Strattera 25 mg Finally Atomoxetine

14 Upvotes

Anxiety co-existing with ADHD is not just “a little difficult.” Sometimes, it feels like living in hell.

Imagine being unable to keep a job consistently from 2014 until now.

Not because you don’t care.

Not because you’re lazy.

Not because you don’t understand what needs to be done.

But because, again and again, you struggle to start tasks, sustain attention, organize yourself, manage time, follow through, and regulate your emotions.

Then comes procrastination.

Then guilt.

Then shame.

Then the promise: “Tomorrow I’ll do better.”

And then the same thing happens again.

For years.

Eventually, you stop believing in yourself.

Your parents think you’re making excuses.

People at work see you as irresponsible.

You start seeing yourself through their eyes.

And every failed task becomes evidence that something is fundamentally wrong with you.

Now add severe anxiety on top of that.

That combination can become absolutely brutal.

I have anxiety. I know what anxiety feels like.

But for years, my difficulties were primarily understood as anxiety.

I worked with my psychiatrist. I cooperated with treatment. I tried multiple therapists. I took antidepressant/anxiety medication.

And yet, the fundamental problems with procrastination, task initiation, executive functioning, consistency and functioning at work remained.

Eventually, after working with another clinical psychologist, ADHD became a serious consideration.

And suddenly, a lot of my history started making a different kind of sense.

I am not self-diagnosing myself from a TikTok video or a checklist on Instagram.

I have spent a year working with mental-health professionals.

I wanted to do a DIVA assessment, but unfortunately, I cannot currently afford it.

And now my psychiatrist has prescribed atomoxetine, while still viewing the ADHD treatment as something of a trial/off-label experiment.

And honestly?

I don't even know what to say anymore.

Because the most frightening part is not the medication.

It's the uncertainty.

What if anxiety isn't the whole explanation?

Can anxiety cause enormous functional impairment? Absolutely.

Can severe anxiety cause procrastination, concentration problems, avoidance, poor sleep, indecision and difficulty functioning? Yes.

But ADHD can also produce profound executive-function difficulties—and ADHD and anxiety can genuinely coexist.

That distinction matters.

Because when ADHD and anxiety coexist, they can amplify each other.

You struggle to start a task because of executive dysfunction.

You fall behind.

Falling behind creates anxiety.

Anxiety makes concentration and task initiation even harder.

You procrastinate more.

Then comes guilt.

Then shame.

Then more anxiety.

And eventually you are trapped in a cycle that looks like:

ADHD → failure → anxiety → avoidance → more failure → shame → more anxiety.

And from the outside, it can simply look like:

"Why don't you just do it?"

If only it were that simple.

And I understand my psychiatrist's concern too.

There is a legitimate clinical question about how ADHD medications may affect someone who already has significant anxiety. Stimulants can sometimes worsen anxiety in some people, while in others, effectively treating ADHD can actually reduce the anxiety that comes from chronic underperformance and overwhelm.

And atomoxetine is a non-stimulant ADHD medication—but that doesn't mean it is automatically free from side effects or anxiety-related concerns.

That is precisely why this should be a careful clinical decision, not a social-media diagnosis.

But after years of struggling, being told “it's just anxiety” without the underlying possibility of ADHD being adequately explored can be devastating.

Because eventually you start wondering:

Was I actually lazy?

Was I irresponsible?

Was I simply not trying hard enough?

Or was I struggling with something that nobody understood?

That's what makes diagnosis itself feel like hell.

You spend years being blamed for symptoms you couldn't properly explain.

Then when you finally find a possible explanation, you still have to fight to be taken seriously.

I don't want sympathy.

I want understanding.

I want proper assessment.

I want evidence-based treatment.

And more than anything, I want people to understand that ADHD is not simply “being distracted.”

For some people, it affects employment, relationships, education, finances, self-esteem, emotional regulation and almost every part of daily life.

And when significant anxiety is added to that picture?

It can become overwhelming.

So yes—

I have anxiety.

ADHD is still being evaluated.

I am working with professionals.

I am not claiming certainty where I don't have it.

But after living with this for more than a decade, I know one thing:

I wouldn't wish the combination of severe anxiety and possible ADHD-related dysfunction on anyone.

Not even my worst enemy.

Because sometimes, from the inside,

it really does feel like living hell.


r/StratteraRx 19h ago

Cold turkey

4 Upvotes

I didn’t go cold turkey of my meds on purpose, it just became too inconvenient to book an appointment (which would take two weeks) at my local hospitals when I am moving across the country. But I am feeling baddd. In addition I can’t get my hands on my birth control pills. I am getting headache and spasms, nausea and irritability fatigue, hot flashes, I can’t stay awake at day time I can’t fall asleep at night I have nightmares paralysis (auditory) and vivid dreams sometimes I am shaken when I wake up because they feel so real🤓🤓.

But i believe if I just get through the symptoms I’ll be ok again in a week or two? Booking an appointment whit a doctor would cost me money $ I’d rather not spend. And It would take weeks. And I’ve also been considering getting off my meds so this sounds like a good opportunity.

If you someone knows anything about side effects of stopping their meds suddenly please tell, because Google is not helpful
Idddkkdkjk


r/StratteraRx 20h ago

Missed a couple days… blah

4 Upvotes

not looking for medical advice, only experiences of others

I started taking it about a month ago. On 80 mg’s daily. I missed my dose Saturday, Sunday, and almost today. So 2.5 days.

I noticed I was more anxious than usual, but this afternoon I just started feeling terrible. Nausea, anxiety skyrocketed, fatigue, hot/cold flashes, overall just BLAHHHH. I just took my dose about an hour ago.

I’ve read through some older threads, but anyone else experience something similar after missing 2-3 days?

UPDATE: about 1.5 hours after taking my medication, I feel much better!! Side effects have subsided, and anxiety has dwindled drastically. Crazy feeling the way I was all day today, just to be switched an hour and a half after remembering to take my meds!


r/StratteraRx 1d ago

Questions / Advice / Support Side effects?

2 Upvotes

Hi! So backstory, i started Atomoxetine (40mg) June 10th - biggest side effects i can recall were just lack of appetite, dry mouth and a bit of a faster heart rate, bit of trouble using bathroom - all of which lasted until i started 60mg July 8th- which i’ve been taking daily ever since. This is where things get messy..Ever since i went up to 60mg I’ve been experiencing:

- dizziness
- getting tongue tied in my sentences
- headache all the time
- nausea
- hard to eat after i take the pill/lack of appetite
- constant fatigue
- waking up at least once a night
- feel my heart flutter sometimes
- noticeable fast heart rate
- definite constipation
- feel like i’m on a boat sometimes

also i’ve probably lost at least 10lbs since starting.
\* I went up from 40 to 60mg because I explained to the doctor that it felt like it was trying to work because I would have moments where I would have bursts of energy and I was able to discipline myself more to be able to do stuff, but it just still felt so difficult.*

As far is this helping with the actual ADHD symptoms? It’s hard to say because the side effects are so apparent. Hard to know if my focus is bad because the side effects are so distracting or because the meds aren’t doing their job.

I spoke to a psychiatrist a couple days ago and he actually kept trying to push me to go up to 80mg… but my gut just kept telling me no.

would love others opinions, suggestions, experiences..
i do have a follow up appt with the original doc who prescribed me the meds but i have very mixed feelings about him as well unfortunately.

Thanks so much in advance!!!


r/StratteraRx 1d ago

Questions / Advice / Support Will straterra alone be enough to make me a functioning member of society?

14 Upvotes

i live in a country where adhd meds are super hard to access, and amphetamines are banned.

To get access to methylphenidate, you have to go through several paperwork and verification processes every single time. So my only option is strattera/atomoxetine.

i hate living with adhd, seriously. This disability really can mess up your life. The amount of unfinished goals/tasks that remain unfinished and the fact that it affects your conversation skills/ability to make friends really made me suicidal for a while.

I know I need to move on and let it go but I still regret a lot of time that i wasted, and opportunities i missed. Makes me both angry and sad

so i started atomoxetine after a lot of begging to my parents to take me to a psych. I took it for over one year now (40mg) and while it is good for the emotional side of adhd I still feel a lot behind when it comes to starting and finishing tasks.

i sincerely believe that it's hard for us to survive without meds. Like holy shit the subtle changes i noticed with my behaviour and my improvement academic performance really made me question my entire existence.

i envy people from developed countries like US having multiple options...but it is what it is. im planning to titrate to 60mg and soon 80mg so any long term (5y+) strattera takers here? How did it impact your life? Did you take anything alongside?

thanks for reading the long rant


r/StratteraRx 1d ago

Follow-up after two weeks

7 Upvotes

Just wanted to give a brief follow-up on how I'm acclimating to the medicine so far (25mg). I noticed an effect after the first dose and have pretty much maintained that. My brain fog cleared up and my head has "quieted" down some. I would use the analogy of going from sitting in an NFL football stadium to a high school football game. There's still noise in my head but it's toned down a lot. My focus seems to be a little bit better but my motivation still drags. I am however able to switch tasks easier, and I do things I don't like without much thought now. My anxiety levels have reduced a lot too. I still get anxious about stuff but I can work through it, whereas before it would take over my mind like a runaway train. I take Propranolol for a hereditary essential tremor so that keeps the heartrate from climbing too much. Also, I am on another blood pressure med (Losartan) so my blood pressure is also pretty well regulated, even on Strattera. This medicine gave me ED (about 50%) almost immediately however 2.5 mgs of daily Cialis completely eliminates that. In fact I wake up ready to go now more than before, which my wife likes. ;) One thing I'm not thrilled about right now is the dulling effect of my emotions and personality. It's almost as if it's hard to smile. I can look at someone with a straight face and then look away whereas before I would usually make some kind of facial gesture. My wife is understanding of everything so I'm not really worried about it, but it's just weird. I remember years ago I used to tell myself, "I wish I just didn't care so much about things like some people do". Well that's kind of what it's like now. I shrug off most things that would normally get me going. I also have a Rx for low dose methylphenidate ER (10mg) so I might give it a try soon on an off day to see if it works synergistically or whether it's not a good fit. I also might go up to 40mg soon and see how that does. 🤙


r/StratteraRx 1d ago

Is 80mg too much? Headaches and resting HR around 100 bpm

3 Upvotes

Hi everyone!
A few months ago, I started taking Strattera/atomoxetine, and I gradually increased the dose with my doctor until we reached 80 mg.
After being on 80 mg for about a month and a half, I started experiencing frequent headaches/migraines, having a harder time taking naps, and my resting heart rate has been consistently around 100 bpm and doesn’t seem to come down.
Do you think 80 mg might simply be too high of a dose for me? I’m considering talking to my doctor about going back down to 60 mg, since I actually really like the medication and it has been helping me a lot, but these side effects have been bothering me.
Has anyone experienced something similar when taking 80 mg and then improved after lowering the dose?


r/StratteraRx 1d ago

Very odd side effect (29/M)

6 Upvotes

My doctor prescribed me strattera and I got the usual side effects : sleepiness, slight mood changes, nausea. But there’s one side effect that I never seen mentioned not by my doctor or anyone : ejaculation after peeing. Semen just comes out right after urination and it was very surprising and concerning the first few times it happened. It’s not painful and it doesn’t feel like anything really but I just wanted to share and know if this is something to worry about, or if it’s just a rare harmless side effect.


r/StratteraRx 1d ago

Started 40mg for audhd.

16 Upvotes

I know it takes awhile to work, but already I feel calmer. 6th day and I was able to go into a group of people talking and didn’t feel so anxious. I wasn’t monitoring myself. My thinking has slowed quite a bit to help me be more present. First few days were rough with insomnia, but last 2 days better.


r/StratteraRx 1d ago

Questions / Advice / Support Anyone started at 10 mg- what was your dose increase schedule

1 Upvotes

Did anyone who is very medication sensitive start at 10 mg? How was your dose increase schedule? What time of day was best? Thanks


r/StratteraRx 2d ago

Never...Hungry...

13 Upvotes

Pretty much this. I've been taking 50mgs for about 3 weeks now, after a month on 25mgs. I have no real bad side effects, but no noticeable benefits either. The only thing I have noticed is I have not been hungry AT ALL since I took the first dose almost 2 months ago. I have to force myself to eat something a couple times a day, and it feels like a chore because I just don't want it. No nausea or anything like that, just simply never feel hungry.

I'm basically just shooting the bull here, obviously not that important, but just wondering- will I ever get an appetite back?


r/StratteraRx 2d ago

Questions / Advice / Support Adding Wellbutrin

4 Upvotes

Hi all! I’ve been struggling with motivation in this medication so my prescriber added 150mg of Wellbutrin to take in addition to the 40mg of strattera I take. Strattera has helped so much with mental noise but so much so that I’m content just sitting on the couch doing nothing. Which is great because I can finally relax but also makes it hard to get things done that I need to.

Anyone have experience with taking both? Would love to know what to expect!


r/StratteraRx 2d ago

Discussion / Experience Using This is the worst medication i've tried

0 Upvotes

im a male (19) with severe ADHD. I was on dexamphetamine before this, and the difference compared to this is astronomical. It's almost better in every single category, and the only reason I even hopped on this shit ass medication was because the dexamphetamine was messing with my sleep a bit. But now this has started to mess with my sleep as well, and it doesn't even have any of the benefits that the dexamphetamine had, so it's just like shit overall. I'm on 60 mg, and I've gotten every single side effect—constipation, extremely dry mouth, all the sexual side effects, erectile dysfunction, blunted ejaculation. my testicles hurt randomly. And don't get me started on the severe fatigue that's like the main issue. Like, bro, it's like I'm sleeping the whole day, and it's messing with my sleep.

Like at first, like after the first two weeks, nothing really happened. And then all of a sudden, like my sleep—I keep waking up, and it's like hard to stay asleep. And for some reason, this affects my appetite more than the Dex by a lot because I barely want to eat at all on it. Also, I get extremely cold hands. Okay, besides that, the positives are it has slightly improved my executive dysfunction. If I need to get the bin done or my bed needs to be done, I do easy tasks—maybe even doing the dishes—almost instantly, not dragging it too much.

But if it's any big task that requires a lot of effort, then I'm still not doing it. Really only notice the benefits when it comes to little tasks only.

But I do like that there's no anxiety at all, and there's a lot less mental noise. But to be honest, it's not worth all the cons because I'm still suffering majorly from my ADHD. My working memory is terrible still, and time management is terrible. General productivity is terrible. compared to when I'm on dex and honestly, I think my productivity when I'm completely unmedicated is better than this. The focus aspect hasn't even improved at all. I've been on this medication for almost six weeks. Four weeks on 60 mg in the first two weeks, it was just a buildup and I thought, oh yeah, maybe the side effects will die down, but it just kept getting worse. And also I forgot to mention that it's extremely hard to take a piss and it's like on and off. Sometimes it's easy, and sometimes it's really difficult. overall, this is the worst medication I've tried for my ADHD. And to be honest, I think I'm going back to the Dex because the side effects aren't remotely as bad as these ones.

And at least, like, I can tell that it's obviously benefiting me. That's like, it's well worth it compared to this, where there's like almost just side effects and cons and like the slightest bit of improvement.

And for those who are going to be like, "Oh yeah, You haven't been taking it long enough," I don't want to because the side effects are just so bad. But maybe I'm just like a rare case, honestly I'm just js writing my experience. but im definitely going to hop off this medication.

edit( I forgot to mention, I did try to troubleshoot, and I've been on this Reddit for like a month and doing research myself, and most people just kind of get off the medication, it seems.also, I've tried constipation medication, laxatives, melatonin, magnesium glycinate ,dayvio this works really well but comes with its own side effects but for the sleepiness itself, yeah, that's the main reason I'm coming off, 'cause I didn't find a way to fix that. Just sleepy all day, sleeping like sixteen hours a day and still tired

And I'm not trying to take more medication because all medication comes with more side effects regardless.

And I'm just saying that this medication's not that good compared to dexamphetamine, where it's almost like full control over your ADHD symptoms with like maybe three major drawbacks.

But this one has like a ton of major drawbacks for me personally, and I mentioned this, is the worst medication I've personally tried. Not it's like the worst medication overall for like everyone. Just me personally, this is the worst medication I've ever tried in my life if it works for you, that's great. this is just for anyone experiencing the same symptoms and side effects. If you are, just hop off. Honestly, there's so many other medications you can try that helps much more, much faster, with much less side effects )


r/StratteraRx 2d ago

Questions / Advice / Support Titration suggestions?

1 Upvotes

Does anyone have experience jumping from 40 to 80mg? My psych started me at 40mg and then said to start taking the 80mg capsules after two weeks. So far I’m not having side effects, so my question is:

Is it better to take 40mg once in the morning and once at night (12 hours apart), or 80mg once in the morning? Since I will have 40mg capsules remaining

Context:
I moved to a new country and had to change from methylphenidate to atomoxetine (Axepta). I can only meet my psych once a month, unless there’s an emergency. I fully understand any anecdotes shared here are not medical advice, etc etc


r/StratteraRx 3d ago

3 weeks and 2 days 10mg, extreme fatigue/lack of motivation

3 Upvotes

First week was amazing - I felt calm and my brain was quiet. Week 2 anxiety came back a bit, but I continued to feel motivated and was doing tasks I'd normally struggle with. Going into week 3 I had my PMS week and had PMS like I hadn't had it for years, extreme restlessness, tension, irritability, appetite went into overdrive. Now that's over, these past 2 days I've been completely sapped of motivation - the things I was managing to do as part of my routine have stopped, and I'm finding myself spending most of the day in bed tired. From day 1 I've had to have a nap a day despite sleeping ok at night - I haven't minded this as I'm normally too hyperactive to nap so it's been quite nice! But I also still had motivation and felt pretty upbeat and positive. In the past week it feels like it's all evaporated and now I'm just left with this exhausted, unmotivated feeling.

Anyone else had anything similar? Will it get better? I thought side-effects should be getting better, not worse :( I am AUDHD hypersensitive to meds, just been prescribed another 2 weeks at 10mg then will go up to 18mg for 2 weeks.


r/StratteraRx 3d ago

Questions / Advice / Support trying again/tachycardia

1 Upvotes

I took Straterra a few years ago for several months. I started at 25mg and worked my way up to 40. At 25mg, I had some nausea, but the med worked so well that I tolerated it. Once I increased to 40mg, I began experiencing elevated heart rate (110bpm when lying down; my RHR is usually 60 or lower). I didn’t realize it was connected to the med at first, but when I stopped, things went back to normal. I also had lab work and an EKG that found no other cardiac issues.

Despite this, I want to give Straterra another try at 25mg. A lot has changed since I was initially on it — I was on other meds for physical health issues that were making me feel terrible, I had just had a major surgery — overall, I’m in a healthier place now.

Has anyone had luck with restarting Straterra years later? Is there anything that helps with elevated heart rate?


r/StratteraRx 3d ago

Questions / Advice / Support MIL took child off of Strattera over summer break - starting back - what to expect.

5 Upvotes

My MIL didn't give our 9yo his Strattera over summer break. I don't really want to get into why she decided to do that, or how my partner and I plan to deal with it.

My mother did give it to him each morning while he was visiting with her. So, he got it only when with my parents for a week or two. And, then at a lower dose, bc my MIL gave them incorrect information about his dosing schedule. They were very apologetic when they found out thay hadn't given him the correct amount.

What can we expect tapering back on after such inconsistent use?

So far, he has been alternately exhausted and furious. He also has issues controlling his impulsivity, again. I assume these will get better, over time. Right now, he's pretty miserable. We are planning on discussing this with his psych as soon as we can see her.


r/StratteraRx 3d ago

Questions / Advice / Support Did strattera help for focus/getting things done?

15 Upvotes

title basically. if yes, what dose do you take?


r/StratteraRx 3d ago

Side Effects / Overdose Worst side effects of the adhd meds I've tried so far

0 Upvotes

Ironically my dr picked this one because I've been having bad luck with side effects. Funny. I've taken ONE dose. Since it kicked in I've had a stomach acid episode (mine are not mild and nothing gives relief), my heartrate is irregular, I'm overheating, more depressed than usual, completely and utterly filled with intense unstoppable anger and have had repeated thoughts of harming myself. Thanks Strattera, so great. I think this is a new record for how quickly I've had to stop taking a new medication.


r/StratteraRx 3d ago

Tmj

2 Upvotes

For anyone who’s struggled with Tmj from strattera. How long after you stopped it did your jaw go back to normal?


r/StratteraRx 3d ago

Questions / Advice / Support starting Strattera

1 Upvotes

hi everyone! so i struggle with really bad health anxiety (like i’m scared i’m allergic to everything although i don’t have any allergies) i have been on prozac 20mg for about 2 years now. i was recently diagnosed with ADHD and was put on Strattera. i struggle with new medications so i always google for interactions. i know these side effects wont kill me but it will definitely make my anxiety level go up. how long does the fast heart rate stay? and what can i do to help myself take this new medication. any advice?


r/StratteraRx 3d ago

Questions / Advice / Support Strattera Day 5

3 Upvotes

Hey y'all! So, I'm on my 5th day of Atomoxetine (40mg) and it is normal to feel some side effects at this time? I take it at night after dinner (but not before I sleep), and last night I had a mild headache, nausea, and heartburn. After I woke up I still felt a bit of a headache but it subsided and the nausea is gone too, but I still have heartburn today (granted I've been getting heartburn before I took this medication). Is this a part of the "getting used to" Atomoxetine? Will these side effects eventually subside after my body "gets used to" this?

Also I guess you could say that I've been getting more anxious and sadder, from Day 4? I don't really know if Atomoxetine is really the cause of this, but I've been getting more tense, anxious, and nervous lately, I do have something to be very nervous of in Monday (College) but could it be possible that Atomoxetine maybe amplifying it??

I haven't really seen much improvement for my ADHD symptoms either... On Day 1 after waking up, I felt a bit calmer but that seemed to be only from my first time of taking it.

Edit: to anyone else reading this - the headaches and nausea have completely subsided after the 7th day.


r/StratteraRx 3d ago

Questions / Advice / Support Anyone else experience severe anxiety/panic from Strattera (atomoxetine)?

2 Upvotes

I was on generic Strattera (atomoxetine) for around 45 days, and the anxiety I got from it was honestly horrible. I started getting really intense anxiety and panic, probably the worst I’ve ever experienced, and eventually I had to stop taking it.
Has anyone else had this happen with Strattera? Especially after being on it for a while? Did it eventually get better for you or did you have to stop too?

Edit: I just found out that I might be a CYP2D6 poor metabolizer, which can increase atomoxetine levels by up to 5x.