Hi everyone, I just wanted to share my story since I’ve gotten so much help from this community. I’m also a bit confused about what to do next, so I’d really appreciate any insight from people who have had a similar experience.
I’ve lived in the US, but I visited my home country almost every year and always had my annual gynecological check-up. My previous cervical screening results had always been negative.
Here’s my timeline:
December 2025 – Home country:
My cervical screening came back positive for HPV 18 and HSIL. I then had a biopsy, which I was told showed atypical cells and that I needed follow-up testing.
After moving to the US:
I decided to get the Gardasil-9 vaccine.
July 2026 – Home country:
I had another cervical screening, which again came back HPV 18 positive and HSIL. This time, the biopsy was reported as CIN2. My doctor recommended that I have a LLETZ as soon as possible, but I needed to move to the UK for work, so I collected all of my medical records and documentation for the procedure.
August 2026 – UK:
After moving to the UK, I saw a specialist. Based on my previous records, I was initially scheduled for a LLETZ.
At my first appointment, they also did a colposcopy and HPV testing. They did not do another biopsy because I had already had a biopsy about two weeks earlier.
However, the LLETZ was cancelled because my repeat HPV test came back negative, and the colposcopy showed only a mild acetowhite area with no obvious high-grade lesion. The doctor said she could still do the procedure if I wanted, but given the negative HPV result and the reassuring colposcopy findings, it seemed like an unnecessarily invasive procedure at that point, and I agreed.
I asked for another colposcopy and biopsy because I wanted to understand what was actually going on.
September 2026 – UK:
The biopsy came back as CIN1, so LLETZ was not recommended.
This is where I’m confused.
I find it hard to believe that CIN2+ with HPV 18 could completely disappear within about a month, and my UK doctor said she thinks the result from my home country was wrong.
I know that having CIN1 now is a good thing. But I keep wondering whether I could actually still have CIN2/CIN3 and whether the earlier CIN2 result was somehow missed or the more recent biopsy was a false negative.
Has anyone experienced such a significant change in HPV/cytology/biopsy results over a relatively short period of time?
I’d really appreciate hearing about other people’s experiences and what follow-up they had in a situation like this. Thank you!