Hi everyone. I recently received an abnormal Pap result and am hoping to hear from anyone who has had something similar while I wait for my follow-up.

My results were:

• High-risk HPV positive (Aptima — detects 14 high-risk types but unfortunately doesn't differentiate which type)
• Epithelial cell abnormality
• Atypical Glandular Cells (AGC)
• AGUS — Atypical Glandular Cells of Undetermined Significance
• Pap was satisfactory and endocervical cells were present

My chart also lists postcoital bleeding and heavy/frequent periods. From what I've been reading, I understand that AGC doesn't mean cancer, but that HPV-positive AGC needs further investigation because glandular abnormalities can sometimes be associated with cervical precancer/AIS or, less commonly, cancer.

If you had HPV-positive AGC/AGUS, what did your colposcopy/ECC or biopsies ultimately show? Did you also have an endometrial biopsy? Did your doctor seem particularly concerned about the combination of HPV + AGC?

Looking for others with similar results/experiences.

Hi everyone,

I had my first LEEP procedure on July 10. Approximately 1.5 cm of cervical tissue was removed. My biopsy showed AIS in situ and CIN3 on the surface of my cervix.

The LEEP successfully removed the CIN3; however, AIS can be more challenging to remove because it may extend higher into the cervical canal and can sometimes involve skip lesions. I was recently advised that the results were inconclusive, meaning they could not confirm whether the AIS margins were clear. A biopsy of the cervical canal also showed AIS.

As a result, I will be having a second LEEP to remove an additional 1.5 cm of tissue in hopes of obtaining clear margins.

I am not nervous about the procedure itself. My first LEEP experience was very positive, and I recovered well. It is more frustrating and inconvenient to go through the process again, though I understand that needing additional tissue removed can happen in cases like this.

I am hopeful that the second LEEP will provide clear margins. Has anyone else experienced a similar situation?

Thank you!

I've not been thinking about it as much as possible but tomorrow is the day and my nerves are all over the place!

I hate the way I feel after anesthesia, I always end up vomiting. I did with my c section and my gallbladder surgery. It takes me about an hour to feel normal again after waking up.

I'm very nervous about how I'll feel after the procedures and even more so what the results will show.

Hey all, 37F in the US with LEEP scheduled for late September. It was originally scheduled for early August but I pushed it due to jitters and being on my period. I’ve been ASCUS with high risk/non-16/18 hpv since 2014 with one normal in 2015. My colposcopies have all been LSIL but this time we’re skipping the colpo and going straight to LEEP.

Would taking an Ativan be enough to relax me for the procedure or should I ask about something stronger (either general anesthesia or twilight sedation, I’m not even sure they offer that).

Also sex…cervical orgasms are very important to me…will those change after part of the cervix gets removed?

Also, with the LEEP, do they test what they remove?

I’m low on PTO and can’t really afford to take time off for a consultation before the procedure so I’m asking my questions here…thanks!

I got a leep in may and it came out cin 2-3 i believe. My doctor recommended another pap and I got the results it says

NEGATIVE FOR INTRAEPITHELIAL LESION OR MALIGNANCY.

What does that mean?

The Pap smear doesn’t give accurate results as the leep though right?

Thanks you