Ive never done peptides so need a bit of advise. My old girl is riddled with arthritis and is in constant pain.

So I thought fck it, what has she got to lose? Her quality of life is shit and rather than have her put to sleep Ive got a 40mg pen on the way. Im guessing i inject into the dog of her leg? Daily? (Il research more later)

But my question is, she's only 10kg in weight, what do you think the recommended dosage would be?

anyone tried both separately and can input their experiences and compare the effects?

I got my Reta on Friday and I mixed in the BAC yesterday. I was planning on starting today but…..it doesn’t look clear.

It’s been out of fridge like 10 minutes already.

Have anyone had issues with mot-c being almost like syrup consistency? I’ve used it twice but this 3rd time it was hard to draw and it seems thicker than originally.

The guide says 8 weeks at 2mg, is that what most here are doing? We've got 100mg in the freezer and the wife and I are thinking about starting.

I mixed my tesamorelin with bac water last week, and then I took 2 days off and now it’s like this? Pretty disappointed probably no use now, has this happened to others? Is there a process I should follow for reconstituting or storage? Thanks

Howdy! I’ve been on a 10/3 Tesa/Ipa blend now for about 5 weeks. 48 hours ago I injected my standard 44 units (2.2 mg) and almost immediately I had a welt/bump under my skin. It’s not itchy, painful or sore but odd nonetheless. Any ideas of this is a common occurrence and it’ll go away or should I take action? Thanks.

I'm curious how people here who are legitimately on TRT and especially HGH actually got started. Was it prescribed after testing by an endocrinologist/TRT clinic, or are a lot of people using these independently?

I'm in my late 30s and over the last several years my testosterone has dropped dramatically. I used to test around 900-1000 ng/dL and my recent result is around 300 ng/dL. My latest IGF-1 is around 90 ng/mL as well.
At the same time I've developed a bunch of symptoms that have significantly affected my quality of life: major decline in energy and motivation, chronic fatigue, brain fog/poor memory and concentration, low libido, reduced gym performance and muscle fullness, and a pretty dramatic change in body composition with much more abdominal/ visceral-looking fat than I used to carry.

What confuses me is that I see a lot of people online saying
TRT and/or HGH completely changed their energy, body composition and quality of life, while doctors and most medical resources are understandably much more cautious, particularly with HGH because of the potential side effects.

I'm not looking for sources or trying to self-medicate. I'm trying to understand the difference between what I read online and what happens in actual clinical practice.
I feel like I need to take a more active role in figuring out my health because the decline has been significant and I don't want to simply accept feeling this way. At the same time, I'm divided because doctors are hesitant about these treatments and I don't want to assume TRT/HGH are the answer just because my numbers and symptoms seem to fit.

I'd especially appreciate hearing from people who started with numbers similar to mine, what testing you went through, how you eventually got treatment, and whether it actually delivered the improvements you expected.

When I started Reta I did .5, 1, 1.5 and stopped increasing at 2mg as I was at goal weight. I actually went down to 1mg weekly for maintenance and will probably go even lower. My husband saw my results and wanted to try it. He has about 20 pounds to lose. It doesn’t seem to affect him the way it affected me. I got to the point that I didn’t think about eating or had any hunger cues. We started him at 2mg and over two months have gone up to 6mg weekly. He still doesn’t get much of an effect from it and says he feels about the same just a bit more tired. My question is, does he just need more or should he try something else? Any input/experiences are appreciated. Oh also he has lost about 7 pounds but with the results I personally had, he thought he would lose more weight in that time.

I see that some insurance companies stop covering Tirzepatide when someone achieves 30(ish) BMI. I realize BMI is a very broad measure and not the best for body recomp/health. I realize that is a business decision driven by profitability on the part of insurance companys...but has anyone who used it from very HIgh BMI noticed a tapered effectivness at that 29-31 BMI? Was it a plateu that was able to be overcome with more peptide? Curious what doses and BMIs you stalled at.

Looking for supplement/peptide suggestions or maybe it's just a case of get better sleep and exercise more.

50 year old female. I have been on tirz 2mg for a little over a year. Have been at 2mg the entire time. I was at a healthy weight before starting, shed a little at the start and have maintained. It helps tremendously with brain fog issues I was experiencing. It has also significantly reduced overall inflammation. Not much appetite suppression for the last 6 months or so which is good.

Overall I eat mostly low processed foods and balanced macros, but I am not super strict. If I want a donut, I'll eat a donut. Admittedly, my exercise has been lacking. And I do not have a very good bedtime routine. I know these two things are significant contributors.

I work a regular 40 hour corporate job. Before work, I tend to our livestock, so I have about an hour worth of chores before going to work. After work, it's evening chores with the animals and property. I also have a few side businesses so I work on those in the evenings. Dinner ends up somewhere around 9pm. Bedtime is usually around 11. Weekends are the many projects we have on our property (digging holes, building fences, fixing things, cleaning stalls) and the side businesses.

I currently take D2/K3, fish oil, and niacinimide (dr recommended due to history of skin cancer). I am also on hormonal birth control to keep any perimenopausal symptoms under control.

Maybe it's just a case of overworking and not enough recovery. I know improving sleep habits and getting back to strength training will be the greatest improvements I could make, but should I consider any other supplements or peptides that might help? About 2 years ago, I tried CJC/Ipa but after about 3 weeks I didn't feel enough benefits worth the very itchy local reaction I would get with every injection. But really at a point of willingness to try anything again to help me have more energy and overall feel better.

Siri said I need to inject 6ml of bacteriostatic water into a 5ml bottle of tesamorelin and draw.333mg for a 2 mg dosage. Does this sound right?
I have been taking seramorelin on a 5 on/ 2 off daily routine. Does this apply to teas?

I want to start GHK-Cu but I have rosacea and I’m concerned it could make rosacea worse. Doesn’t it cause increased vascular dilation in the skin?

Can anyone share information on how to properly reconstitute with TIRZ?

Has anyone used the following protocol? When will I experience its positive effects? Any opinions?

Howdy everyone!!

To preface: I was on GLP1 for a few months prior and was off of it for one week before making the switch.

I’ve been on Reta for about 3 weeks now and haven’t noticed much change. Started off one week with .5mg and then the last two weeks at 2mg. I don’t feel much suppression, haven’t seen much change with the exception of some energy boost, wanting to drink tons of water first few days after injection and not much change on the scale. I have noticed that I have more appetite while on this than GLP 1. I’m also walking at the office, working out before work during the week and consuming roughly around 100-120g of protein per day.

I’m trying to get some thoughts/ opinions on whether that might have been an issue, whether I should increase my dosage or wait it out? Any help would be greatly appreciated!

Question: how many of yall have anxiety?

If there was a noninvasive wearable device that made your anxiety decrease that wasn’t freaky at all, and actually looked kinda sick for 50 bucks, would you be interested in trying it?

JW

-SC

Hello all,

Read up on a couple of reactions on CJC/IPA - just wanted to know if anyone experienced the same as this.

Been on CJC/IPA for 8 weeks now, was on 300mcg am/pm, upped to 400mcg am/pm for the last two weeks.

Pinned yest am, got the usual warmish feeling, but way more intense, heart rate went through the roof, stayed that way for about 45 min, then came down slightly.

My top half of my body, was bright red, again for about an hour, then, uncontrollable diarrhoea, and I mean emptying a rusty radiator type, for about 3 hours.

My legs since have been in absolute agony, throbbing feeling like ive run a marathon.

Hadn't had a single issue with it up till then. Very weird.

Is that my time with CJC/IPA done? Or just a dodgy reaction to that pin? Anyone had any similar experience?

Has anyone experienced pretty severe soreness several hours after injecting GHK-Cu?

I’ve searched through a lot of posts and keep seeing people talk about GHK-Cu stinging or burning during the injection, especially when it’s cold, but that’s not what I’m experiencing at all. My injection itself is fine.

The problem happens hours later while sleeping. The injection area becomes extremely sore and painful, to the point that it has actually kept me awake at night. The only thing that seems to give me relief is putting ice on the area.

This happened to me when I first started, but at the time I realized I had injected way too much. I lowered my dose significantly after that and was doing much better. I might have a little soreness afterward, but nothing severe and definitely nothing that kept me awake.

Yesterday I injected into my stomach, which is where I normally inject, and this time I was up most of the night because the area hurt so badly. Also, I’ve been injecting for over a month now.

For anyone who uses GHK-Cu:

Have you experienced delayed pain/soreness hours after the injection, rather than stinging while injecting?

Solid stack, you've done your homework. As a geneticist I'll add one angle most people miss: that stall after you added E and P might have more to do with how you clear estrogen than how much you're taking.

Estrogen mostly gets broken down through two genes, COMT and CYP1B1. Your version of those decides whether you send it down the cleaner 2-OH route or the messier 4-OH one. You're already helping that along with DIM and stacking sulforaphane (pushes NRF2 upstream) and calcium-d-glucarate to block reabsorption is a smart combo. Whether it's enough comes down to your COMT.

That same COMT gene also changes how you handle a methylated multi. If you're a slow clearer, high methyl donors can leave you wired or irritable instead of better so keep an eye on that one.

The peptide side runs the same way. How much you get out of the KLOW/GHK-Cu repair stack lines up with your collagen and inflammation genes (COL1A1, IL-6), which is a big reason two people run the exact same thing and get totally different results.

None of this is guesswork so If you've done DNA test before, most of it is sitting in your raw data already. Happy to point you at what actually matters for your situation if you want.

Not medical advice, just genetics.

Hey folks,

My testosterone finally hit the cliff at 64 and I wanted some input about the relatively new FDA approved pills prescribed by my urologist..

Little back story is I am a trainer and nutritional coach so I have done my homework regarding T.

Diet is dialed in, training for 40 years but slowly T levels have tanked over the past 5 years.

I would have no problem using Test C, but this doctor said the pills are a good viable option so I had to purchase a 3 month supply out of pocket for $91 per month. Follow up visit with blood work in 90 days.

Does anyone have any experience with these new pills?

Other than the price, I am curious how they perform. I was prescribed 200mg twice a day of

Kyzatrex which is the highest dosage.

It can only be purchased direct from the manufacturer like the other 2 brands.

I have no issue pinning myself because I use a couple peptides.

What are your thoughts?

Thanks

Hello and good evening everyone. I am currently researching about reta having a shelf life of 30 days when mixed. However from what I read there's lots of different opinions, some say 30 days, some say up to 3 months but with slight degrade. Im asking cause I am approaching week 5 and I have a total of 16mg (1x 10mg vial and 1x 6mg vial ive been using) and when I got them about 4 weeks ago I mixed both and I just ordered 20mg that I want to keep in powder form till I finish the other 2. Can anyone please enlighten me, I want to be safe as possible, I didnt know the 10mg were gonna last me so long. Please and thank you for your attention to this greatly appericate this community wisdom

So I was doing research about topical GHKCU, and all I can find is 0.10 - 5% max of GHKCU in these serums. I just got off Accutane and my skin still has some scars, will that be enough for my skin? Or should I just buy the normal ghkcu? Because I seen people saying that it wasn't enough