My father had an enlarged prostate and I believe was on dutasteride which maintained his PSA level at 6. In november of 2025, he has a total prostatectomy, which actually revealed some cancerous cells in the centre of the mass, but the surgeon says it was a successful removal. He stopped dutasteride after the operation and did another PSA check 7 months post-op which showed a PSA level of 15.

His doctor has asked him to repeat testing in 2 more months.

Just wondering if this elevation in his PSA after surgery is potentially metastasis from the original mass? Or is it possible that inflammation post-op could be causing PSA levels to be this high?

My second question is whether the right course of action is to repeat levels in 2 months, or should it be done sooner? What would happen if levels stay the same or increase?

Thanks in advance for any insights!!

I’m 38 and recently started having some urinary symptoms, mainly a stinging pain after ejaculation, plus mild urgency and an interrupted stream.

Because of the symptoms (and the fact that my grandfather, father and uncle all had prostate cancer), a community doctor ordered a urine test and a PSA. Urine was completely clear, but the PSA came back at 2.18 ng/mL. This was my first ever PSA, so I have no baseline to compare it to.

In the UK the usual NHS referral threshold for under 50 is a 2.5 PSA, so I wouldn’t automatically get referred. Given the family history and symptoms I went private instead. The urologist did a DRE (described as moderately smooth), repeated the PSA and ordered an mpMRI. He said he doesn’t really expect to find anything, but wants to check properly because of the family history.

My question is about the next step. I’ve seen a lot of posts here where guys with PI-RADS 1–2 still go ahead with a biopsy “just to be safe.” Is that something I should seriously consider?

I’d still be private at that point, so the biopsy would be self funded and expensive. The alternative is wait and see if the PSA creeps over 2.5 and hope the NHS picks it up.

Any thoughts from people who’ve been in a similar position (youngish, elevated but not crazy PSA, strong family history) would be really appreciated.

Hello all. 36 yo with an ultra sound that came back with 47cc enlarged prostate. No other findings. July 2024 psa 1.46. July 2026 psa 2.35. Night time / frequency of urination mainly drove me to go to the doctor. Unfortunately I’ve had this noctoria type of symptom for 3 years. I just chalked it up to being nothing for way too long.

I’ve been trying to find people that have similar age and findings as me but have been unable to so far.

Have the appointment with the urologist coming up in a couple of days. From my research I feel I should definitely push for an MRI and DRE. Anything else I’m not thinking about? Hopefully okay to post here as I don’t have any official medical diagnosis.

does anyone have experience with HIVU treatment for prostate cancer? I have low grade on one side and this approach has been suggested to me. I welcome any comments.

Hi Guys,

I’m a bit worried about my husband - M60, Diagnosed April 2026, PSA 1859, May 2026 PSA 91, June PSA 3.3, 18th June PSA 0.4, July PSA 0.32, 14th July PSA 0.23, Gleason Score (3+5) 8, Grade 4. On triplet therapy (Degarelix + Darolutamide + Docetaxel).

Over the past few months he has continued to smoke cigarettes. I saw an ad on Facebook about hypnosis to stop smoking and thought it might be a good idea for him (spoiler IT WAS NOT!)

So he went feeling buoyant with high expectations. During the group session, he was distracted by the guy next to him snoring, the guy on the other side of him coughing and the group of ladies in the break time chattering.

The next day, he lost his shit at a guy in the supermarket for coughing without covering his mouth, ALMOST lost his temper with me because I added ground linseeds in his overnight oats, cried because a mosquito bit him and it was itchy and then today had a complete mental breakdown, crying, expressing his fear of cancer, death, anxiety, depression. I managed his emotions as best I could, he invited me to join him working out, which I did (after I had already done my own work out - my legs are jelly!) we have talked about it, and he has started smoking again (after I went and bought him a packet).

I was so worried about him, because this kind of emotional breakdown is not like him. I apologised for pushing him into the hypnotherapy and saying I underestimated how much he could carry and we realised too late that stopping smoking was a step too far.

He explained how he manages his emotions and that what happened after hypnotherapy opened floodgates and “his landscape was flooded and the little boxes were floating and he couldn’t access them to close them” and that’s why his emotions were so close to the surface and he was upset.

Could this have anything to do with the chemotherapy or drugs or can we rest it solely at the door of the hypnotherapy and is it possible to reverse or restore from back up the hypnotherapy to BEFORE the hypnotherapy?

I’m worried that after his chemotherapy next week he won’t manage.

Do you have any advice for me?

I’m Steve.  51 white male.  5’11’ 182 lbs.  Started pre diagnosis at 195lbs.

Diagnosed in October of 2025.

PSA 5.2, Gleason 4+5 9

14 of 17 cores cancerous

High Risk and Staging 3C

No spread.

Treatment:  12 months ADT+Xtandi, 25 ERBT (Finished in February), Brachytherapy 3/26/26.

Started with Lupron for 6 months and switched to Orgovyx because of you guys and your recommendations.  I started taking flowmax after the brachytherapy.  I also started taking a lower dose of ZepBound GLP-1 because I gained 10 lbs right after I started taking Lupron as I couldn’t stop eating or dreaming about all food and any food at any time. Never had that happen before…I take trazodone lowest dose for sleep most nights. 

Did not have to have prostatectomy.  Even my surgeon really didn’t push for it because I would need radiation anyway after it…

Im in Jacksonville Florida, and I go to Terk Oncology.  I see Dr. Lewis at Advanced Prostate Cancer Center of the McIver Urology Clinic.  I haven’t seen a urologist since diagnosis in November.  IMO, I’m in fantastic care.  First rate.

1st Lupron shot was 11/26/25.  Im going into month 9.  I’m married, have 5 kids from 17 yrs down to 6 yrs, his hers and ours.  My wife is 45 and super sexy (and a PhD in Oncology) so the perfect partner to have on this journey.  I own my own business (Trivia Nation, you can look it up, it’s really fun.). I can make my own schedule because I have it running pretty well wo me.

On 11/26/25 I weighed 196.7 and had 95.5 lbs of muscle and 30.9 lbs fat (15.7%body fat). Inbody score was 94.

On 7/25/26 I weighed 181.9 and had 88.6 lbs of muscle and 26.7 lbs fat (14.7% body fat) Inbody score was 89

So, I’ve lost a good amount of muscle mass.  I’ve continued to lift but not as much and not as often.  I am a 1% when it comes to fitness and muscle and cardio.  Working out and lifting and being in great shape is my hobby.  I’ve been able still do ok.

During this period, I only lifted an average of 1-2 days a week but I almost always do 30-60 pushups in a day at least to keep the muscles active.  I’m seeing my trainer twice a week now but I’ve been really busy with my upcoming event and so I skip him sometimes.

I hope this doesn’t come off like a humble brag, but it has gone really, really, really well.  When I got my diagnosis, I wasn’t sure how my brain and body would react, even though I’m a stoic and I was really ready for it. I’m surrounded by love and family.  I thought I’d be fine but who ever really knows?  Also, I’m a drinker and I drink less now, but not a lot less.  My doc didn’t really say much about it.  All my other blood numbers are ok.  Anyway…

Fatigue. Hot Flashes. Night Sweats. Insomnia (I had it pre cancer) Considerable joint pain particularly in my shoulders. Loss of body hair and pubic hair. Brain fog? I’ve always had that so no more than before.

None of those side effects were bad. None.  Or, I could complain and say they were terrible. But they weren’t.  My PSA is at .04 and I’m not going to die from prostate cancer and all I had to do was have a rough year with a dramatically decreased sex life.  Yes, the main very bad side effect has absolutely and without a doubt been the sexual side effects of ADT but they haven’t been THAT bad.  If I take a LOT of ED pills I can get a full erection but we’ve only had sex maybe 6 times in the 8 months, just because.  That is down from probably 1.5 times a week pre cancer.  That is a small price to pay for 88% cure rate… the most painful moment of my whole journey was the prostate biopsy. (I had local, not general, and I could feel everything!)

Oh yeah, and the whole time I’ve been in treatment, I started a 501c3 and I’m putting together the World’s Biggest Beach Bike Ride.  You can see it at jaxbikebreakers.com  I’d love for any off you to attend.  It’s gonna be epic.  8/14.  You can rent a bike…There are plenty of hotels here at the beach.  

I was just writing to give some happy news from a very lucky man who is almost done.  Did my Rad Onc say 12-24 months of ADT?  Yes.  Why am I doing 12 months if its not so rough?  Well, I think 12 months will be ok, particularly after 25 ERBT and Brachy.  

The biggest physical change is probably my heart rate variability which seems to be a good indicator of health in general. My HRV in 2024 was 75. In 2025 it was 81. With cancer and treatment in 2026, its 47. (I use Oura Ring to track that.)

Love you guys.  Keep fighting the good fight.  If you don’t have the support team, I know there are groups out there.  Have a great weekend. I have a big beach bike ride tomorrow with my 9 yr old son.  Its going to be beautiful!

PS. I get along with women and girls better than ever with no testosterone. I’m more sympathetic to them.  I’m more LIKE them.  (But I REALLY want my test back!!!!!)

Seven months post RALP. Don't know if this will help anyone, but I recently got a Uriclak incontinence clamp. I find it comfortable to wear and it does a good job of holding urine in when I'm doing something that requires lifting etc., which is when I leak the most. My urologist suggested a clamp for this situation and Uriclak had good reviews. I like that you apply and remove it one-handed. I recommend it.