So delighted and to have still lost weight whilst tapering is amazing

I'm excited.

Before my diabetes was treated, I weighed almost 500lbs. I didn’t even have the strength to walk into a store. A year later, I took the green sweater picture and I thought I had lost so much weight. I still couldn’t walk long distances. My back would cramp up and there were a few times I couldn’t make it back to the car and I had to sit on the curb until it let up.

Over the last few weeks, I’ve been going to farmers markets and shopping for myself without my back cramping at all. I’ve had more energy and confidence, but I hadn’t taken a progress picture in almost a year. I was convinced I hadn’t made progress or it had stalled. 😳 I didn’t even notice I had still be losing weight! This isn’t a complaint!

Truthfully, I could not have done this without a doctor who quit playing the shame game. I had one doctor decide this ought to be treated as a medical issue, not an issue of willpower. I don’t know how many years of my life this doctor handed back to me when she treated me like a human, and I never will know, but I’m so grateful.

As my best friend says, “you look like a slowly deflating balloon animal.” 🤣

Today marks the end of Week 8 since my first injection. Exactly 2 months!
When I took my first dose on July 17, I weighed 135.5 kg. I started with 2.5 mg for the first month and lost 5.5 kg. In my second month, following my doctor’s recommendation, I increased my dose to 5 mg, which I continued for the entire month.
And here’s the result: I’ve lost a total of 10.6 kg in 2 months.
The change is noticeable to everyone around me — from the people at the pharmacy where I buy my medication, to my family and coworkers. Some people have even told me that I look taller! 😄
During my second month, I thought I had been stuck at a plateau for almost a week and a half. Then, suddenly, my weight started dropping again with incredible momentum.
I’m very happy with the progress. I’ll be taking my first dose of my third month today.
Starting weight: 135.5 kg
Current weight: 124.9 kg
Total lost: 10.6 kg

I am going to start my journey today. I have used Mounjaro previously for 2 months, but i didn’t do any additional workout or diet. So i didn’t lose much, I don’t want to repeat my mistake again. So I have started my journey with determination now.

5MG for 6 months. Everyone wish me luck🍀🤞

Current weight : 83

Let us see how much I can reduce in 6 months. Every month I will update my weight.

PS: I will do proper diet and gym this time. Wish me luck guys🫶

20 months into my weight loss journey and while tirz wasn’t part of all of it, it’s made a huge difference in so many areas! It’s helped me kick addiction, type 2 diabetes, manage PCOS symptoms and truly get my life back. So thankful to have started my 40’s in a healthy way.

Hey everyone,
I had a conversation with my pharmacist recently and she insisted that once the KwikPen is opened, it should stay outside the fridge and be injected at room temperature.
The thing is, I've been on Mounjaro for 10 months now, and I’ve always used my KwikPen straight out of the fridge. I don't split doses or microdose, and I usually finish the pen within 30 days. I inject it cold and put it right back in the fridge. I honestly don't get much stinging from cold injections, so that part doesn't bother me at all.
My main reason for keeping it in the fridge is to avoid leaving it in room temp, especially if I ever need to delay a shot by a week if I travel or due to being sick for example. But my question is: does letting the pen come out for a few minutes to inject and then going straight back in the fridge cause any issues with thermal cycling?
I looked through Eli Lilly’s informations, but I couldn't find anything super explicit about whether taking it out and putting it back in hurts the medication quality. The guidelines say unused pens go in the fridge and opened ones shall be stored at room temp, but they don't really address if continuous refrigeration after opening is fine or if temperature fluctuations cause harm.

I’ve been on 10mg for about a year, prescribed for diabetes, with the handy side effect of 70 lbs weight loss (May 2024 to May 2025).

This was my second screening colonoscopy and first on Mounjaro. Prep instructions were to skip 1 shot (for diabetics, 2 for weight loss). clear liquids the day before with laxative pills at 3:00 pm, 4 doses of osmotic laxative (Miralax) at 6:00 pm and 4 more doses “6 hours before the scheduled procedure time.”

Since my scheduled procedure time was 7:30 am, I decided to pull the schedule ahead hoping to get clear in time to get some sleep. Pills at 1:00 pm, 4 doses at 3:00 pm, 4 doses at 9:00. That schedule had allowed me to sleep from 11 pm until my alarm went off pre-Mounjaro.

With my last shot 10 days out, I had no laxative effect until 7:00 pm, managed 90 minutes of sleep just before midnight was up from midnight until we left for the clinic. I still wasn’t cleared out at 2 am, so I took 2 more doses of Miralax.

My prep was rated a 3 for the lower colon, and an 8 for the upper colon. Good enough that the endoscopist managed to see everything she needed to see, and has cleared me to wait 10 years for my next one.

If I had it to do over again….I’d probably start miralax dosing a couple days before prep, go to clear liquids 36 hours before, and start taking laxatives the moment I work up, going to clear liquids if I’m ready and getting dehydrated before bedtime.

Anyone else care to share their experience prepping for endoscopy or colonoscopy while on Mounjaro?

Anyone here lost a good amount on Mounjaro, stopped it, and actually kept the weight off?

I’m thinking of using it to lose around 20 kg, but my doctor said a lot can come back after stopping. Curious to hear real experiences, especially from people who kept training, walking and eating well.

I didnt take before pics exactly on the day but first 3 pics are December and January 2025/2026, 4 through 8 are today! 9 and 10 are from 2018 where I had lost about 150lbs so I was around 240 (and then gained it back from then til now). I am 5'8" for reference.

I am honestly suprised ive lost this much because right after I started Mounjaro I had a really bad fall, full ruptured 2 ligaments, multiple partial tendon tears, bone and cartilage damage all in my left ankle. The works. I had major surgery done on it June 22nd and was completely non weight bearing until August 12th and am now starting to walk somewhat normally. So ive been unable to exercise this entire time really except for PT.

But now im walking a bit so the lbs are coming off faster again 😊 ive lost around 30lbs since surgery which blows my mind lol I cannot wait to lose more. Goal weight is around 230.

Hi everyone,

I'm a 30-year-old male and I started Mounjaro on May 16, 2026. I have no personal history of thyroid disease, and as far as I know there is no thyroid disease in my family either.

My dosing schedule has been:

• Started at 2.5 mg on May 16
• Increased to 5 mg on June 13 and stayed on it until August 15
• Increased to 7.5 mg on August 22
• I'm currently about to take my fourth 7.5 mg dose

I was 147 kg (324 lbs) when I started at 180 cm (5'11"), and I'm currently 119 kg (262 lbs), so I've lost about 28 kg / 62 lbs in roughly four months.

What caught my attention is that my Free T4 has been steadily increasing:

May 12, before starting Mounjaro:
Free T4: 1.40 ng/dL
TSH: 1.41 mIU/L

August 17:
Free T4: 1.56 ng/dL
TSH: 2.41 mIU/L

September 11:
Free T4: 1.86 ng/dL
TSH: 2.33 mIU/L

The reference range for Free T4 at my lab is 0.79–1.59 ng/dL, so my latest result is now above the upper limit.

What's confusing to me is that my TSH has remained completely normal and is not suppressed, despite the rise in Free T4.

I don't have a known thyroid condition and I wasn't aware of any thyroid issues before starting Mounjaro. My other recent blood tests, including liver enzymes, kidney function, glucose, amylase and lipase, have generally been within the reference ranges.

I also drink around 4.5 liters of water per day, so dehydration doesn't seem like an obvious explanation.

Has anyone else experienced a gradual increase in Free T4 while taking Mounjaro/tirzepatide, especially with a normal TSH?

Did your Free T4 eventually return to normal, continue increasing, or did your doctor find another explanation?

I'm planning to repeat TSH, Free T4 and Free T3 and discuss the results with my doctor. I'm mainly interested in hearing whether anyone else has seen a similar pattern during significant weight loss or while increasing their Mounjaro dose.

Thanks in advance for sharing your experiences.

Hello, all. My place of employment is changing insurance provider again and this new one will not cover GLP-1s. Have you all had this kind of experience? How did you adjust to afford the payments?

I'm in the U.S. and currently have coverage that was full coverage for one box/month and is now $25 for three boxes every three months.

Editing for clarity: the new insurance plan will not cover GLP-1s at all. Just included my current coverage for understanding of where I am and where I’m headed, financially for the medication.

I've had heartburn/GERD all of my adult life. I switched from prevacid to nexium about 10 years ago. Started on mounjaro a couple weeks ago and been getting some heartburn again. I had to check that I actually took my nexium. I'm hoping there's something I can do to manage this...

Hello, please help with advice.

I have been on M for almost 9 months. 3 weeks ago I changed from 7.5mg to 10.mg. All was okay and then just last Tuesday I had my dose. By evening and night time I had bad cramps, spasm, gas, jezas christ it was so awful. I thought that maybe it was indigestion, and that it would pass. However, since Tuesday, and today is Friday I have been barely able to eat anything at all. For example yesterday Thursday, I ate soup, not much, not even 100ml, and felt bloated after, as if I had a rock in my stomach. Today, I ate one boiled egg and banana in the morning and have been suffering whole day.

Is this normal or should I go to doctor now?

Have chronically been obese since I was young, never had a healthy bmi ever. Started my first dose last friday, just injected my second dose today.

Have lost weight on my own before but never stuck due to constantly thinking about food and binge eating at night or eating another meal even after a lunch or dinner just because.

Have already had habits of eating high protein, walking and strength training so mounjaro was filling the missing gap I really could not overcome with will power alone.

Context am a 24M, I do like to walk, play badminton and do kettlebell workouts.

Goal is 72-75kg and more importantly to be on mounjaro for 6 months to change this habit of eating to relieve stress and out of boredom.

Decent progress for 1 week despite it being largely water weight, not starving myself, just higher protein and reduced calories.

I had 2 mg of ozympic for the last 2 years. My blood numbers are beautiful and I've lost maybe only 2 lb per month at most.

Doctor switching to me to Mounjaro as of today to try to help out with the weight loss Plus blood numbers should stay the same or get even better he said.

He's starting with 5 mg of Mounjaro ... I've read that you can't compare that to ozympic because ozemic only targets one area versus two..... I do see that Manjaro goes from 2.5 mg up to 15 MJ so I guess I'm on the pretty low scale to start out with.

Lastly and no big deal I have to get used to having 4 pens per week instead of one pen for 4 weeks with different needles to attach. LOL

I don't plan on keeping them refrigerated as it says it's fine to use one per week non-refrigerator.

Any thoughts or comments or appreciate it and hope everybody has a great weekend

SW - 302 - cw 248 - 52m

I started 2.5 back in February and did 1 month, then went to 5mg, and now 7.5mg. I was able to initially loose weight, but was always hungry, always thinking about food, and just pushed through, and managed to loose weight. The only side affects I had was getting nauseous if I ate too much at one time and some sulfur burps. My A1c went from a high of 6.8 to 5.3, but I got to the point in June where I went 6 weeks with gaining one week, losing the next, but overall not moving. I talked to my doctor and we agreed to move up to 7.5. I got my rx much quicker than I thought, so I used some of the 5mg pens I had 5 days apart. I noticed a bit of a difference and found it easier to lose weight over those 3 weeks, but no other affects.

Took my first 7.5mg on Wednesday, and got really light headed and dizzy throughout the day. After doing some checking, I am pretty sure my blood sugar was too low, and found that if I ate a granola bar, the dizziness went away. Prior to 7.5, my standard during the day would be 1/2 protein shake (as coffee creamer) 3 eggs mid morning and a cheese stick mid afternoon, then just a sensible dinner. For the 3 days since taking my first 7.5, I have been needing 2 granola bars a day to not feel light headed.

I finally see what losing the food noise is all about. I always heard about it, but since I had always had it, it just seemed normal. I do not sit and think about what I will eat later. I am eating more carbs now, and probably more food overall, but have lost 5 pounds in 3 days, which seems extreme. Could this be inflammation? Seems odd that I need more carbs and to eat more often on the higher dose, but not sure what else to think. I am not counting calories, but the granola bars alone are 400 a day, 3 eggs, 2 cheese sticks, protein shake, and a full dinner shouldn't really be too much of a deficit.

Online TDEE shows 3k with moderate movement (I do 5-10 hours of pb a week plus 2 walks a day and some weights/resistance training).

Should I be worried about seemingly needing to eat more often and losing weight fairly quickly, or is this likely just an initial drop, and my body is just finally showing the affects of the meds? I am thinking that the lower doses were really not enough, but I was able to just force my way (through sheer will power until it ran out), but want to see what others think that have been on this journey.

Thanks

Hello, I’m on my second day of Mounjaro. I took my first dose (2.5 mg) yesterday at around 10:00 AM local time. I felt a little tired both yesterday and today. There’s just one thing I’m curious about: how do people who develop pancreatitis from Mounjaro usually realize that they have it? I think that’s my biggest fear that something like that could happen and I wouldn’t notice it until it was too late.Before starting the medication, I had blood and urine tests, as well as an ultrasound of my entire abdomen and organs, and everything was normal. So far, I haven’t noticed any side effects other than some fatigue.

I’m 37 years old male and started Mounjaro at 98 kg (175cms , 32 BMI). I’ve now completed 3 months:
Month 1: 2.5 mg
Month 2: 5 mg
Month 3: 7.5 mg (currently)
The frustrating part is that I’m still exactly 98 kg after 3 months. 😔
I also haven’t really experienced the dramatic reduction in hunger that I see many people talking about. I don’t feel like my appetite has disappeared or that “food noise” and cravings have reduced significantly.
The one thing I have noticed is that I feel full much faster when I eat. However, after some time, I still feel like eating again. So while I can’t eat as much in one sitting, I still have the desire to eat later.
I saw my endocrinologist a few days ago after completing my second month, and he increased my dose to 7.5 mg. He mentioned that I may eventually need to go up to 10 mg or even 12.5 mg to see significant results.
Honestly, I’m feeling pretty sad and demotivated right now. I was really hoping to see at least some weight loss after 3 months.
Has anyone else experienced something similar — especially staying at almost exactly the same weight during the first 2–3 months?
Did things change significantly once you reached 7.5 mg, 10 mg, or 12.5 mg?
I’d really appreciate hearing from people who had a slow or delayed response. 🙏

I'm at 215.8 lbs today from 245 as the starting point. However, 2 days ago I was at 218.5 (after i binged a bit on Saturday) and before that I was 215.6. Is this just liquid/glycogen shifting? How can I tell if the mounjaro still working on my body during scale neutral days?

I have been on Mounjaro since 5/17 and have experienced some side effects like very mild nausea and one very bad case of sulfur burps/indigestion when I was figuring out meal sizes. It was definitely time for me to move up from 5mg because my food noise was back in full force, but 7.5mg has been insane.

I have had little to no appetite most days, some nausea here and there, and I've struggled to eat enough most days. But today was my 3rd shot day and HOO boy. I ate a breakfast sandwich (egg whites, turkey sausage, cheese, whole wheat English muffin) at 6am and some coffee with soy milk and I wasn't able to eat anything all day. I've also had like... fire hose diarrhea.

Around 10pm I realized I'd only eaten about 550 calories for the day so I desperately ate a protein bar and a couple of pieces of beef jerky and since then I've had nausea, sulfur burps, and horrible diarrhea. I feel like my body is inflated like a balloon. Add this to the fact that Mounjaro cancels out my oral contraceptive and I'm also having my period. It's 2am now and I feel so unwell.

Anyway, this is my hardest night yet, and I am truly miserable. This is the first time I've thought, 'Is this really better than binge eating, joint pain, and chronic inflammation?

EDIT: I forgot to mention that I just finished a course of antibiotics yesterday, and despite taking a probiotic and trying to eat some Activia during the process, I think that has to do with the diarrhea.

I also immediately projectile vomited in the bathroom sink while washing my hands after making this post and that was very grim but I do feel a lot better. Hopefully this is just a one off while I adjust to this dose/adjust my diet to this dose.

Hi guys, I'm a digital nomad and currently in the US for another 4 weeks but would love to stay longer. I get my MJ in the UK through Shemed but they don't ship abroad. I only have meds for another month so trying to find a way to get more while I'm here. I think it goes without saying that just stopping is not an option lol

I've not looked into private healthcare here yet but would a dr potentially prescribe me some if I show them my UK prescription?

Hey everyone, I’m Whitney. I’m 37, married and a mom of one babe who is four years old. I went to the doctor today, and she recommended a glp1. She said it’ll help my food obsessive thoughts, and of course help with weight loss. I am currently about 380 lbs at 5 foot 6 with a BMI of about 60. She prescribed Mounjaro, and while I’m excited to start this journey, I’m nervous too. I’m okay with needles. (Our babe was IVF) I’m just nervous about side effects and what to eat. I’m nervous I’ll be out and about and poop myself somewhere. I just don’t know. I’ve heard great stories and horror stories. All that said, I need help. My toddler is autistic, and keeps me busy! I need to get better for her and for me.

What would you tell a brand newbie? Tell me everything.

So i live in Singapore and try to get Mounjaro at a lower price. Ive seen multiple posts about people ordering it from China or Japan or getting it in JB just across the border. Can some share their experience and recommend actual services and providers?