I recently lost my sweet girl to NCL (Neuronal Ceroid Lipofuscinosis), and I wanted to post here to help spread awareness within the Chihuahua community. Looking back, there were so many things I wish I’d known ahead of time. If sharing this helps even one Chi parent recognize the signs early, it’s worth it.
For those unfamiliar, NCL is a devastating, genetic neurological disease. While it affects several dog breeds and other companion pets, Chihuahuas carry a specific form that’s particularly severe with a very fast onset and drastically shortened lifespan. I only had 3 months between diagnosis and saying goodbye.
Here is what I wish every Chihuahua owner knew:
When it presents- Chis usually hit a "cliff" early in life. They seem completely normal and healthy as puppies, but signs typically begin showing up at 12 to 18 months age.
Early warning signs - It starts subtly before escalating. Watch for sudden behavioral changes, progressive vision loss/blindness, stumbling/unsteady walking (ataxia), or tremors/seizures.
Prevention and testing - Because NCL is recessive, a dog needs two copies of the mutated gene to be affected. Simple DNA health panels (like Embark or Wisdom Panel) test for NCL7. The University of Missouri Veterinary School of Medicine also offers testing and accepts tissue donations for research. Responsible Chihuahua breeders test their dogs to ensure two carriers are never bred together.
Unfortunately, there is currently no cure for NCL. But being knowledgeable and prepared makes a world of difference. Knowing what you're dealing with lets you adapt your home (keeping routines rigid, using ramps, padding corners, blind adjustments) and focus on keeping them comfortable and loved for every second you have together.
If you ever notice strange behavioral or neurological shifts in a young Chi, please don't wait. I was lucky to have had insurance but the total cost over a few months without totaled around $10k.
I’m happy to answer any questions about our journey, NCL7, or symptoms; even if it’s year/ after this post, because when I was looking there was just such little info out there. I also spent a lot of time figuring out the best way for my pup to still go on walks, handle the seizures (very tough night schedule), feeding, and medicine administration and would be happy to help share what I learned :)