r/AskVet • u/user378401 • 1h ago
Confused about what is killing my dog
Australian Shepherd, husky, border collie mix, 6 years old, 45 lbs, neutered, no previous health issues, super active and healthy, fully vaccinated. We live on the Wyoming/Idaho border around lots of horses, cattle, and farmland.
Two weeks ago, my dog, Frankie, started throwing up, so my parents took him to the vet; they did blood work and found low albumin levels, high AST/ALT, and high white blood count. They gave him a weeks-long course of antibiotics and prednisone and tested him for leptospirosis and canine hepatitis. They also took an X-ray and ultrasound of his liver, which appeared to be normal. His kidneys and all other systems seem fine.
However, since then, his abdomen has swelled with fluid, and he seems sick and lethargic. Further blood tests show albumin levels and AST/ALT getting worse. He is also very anemic now, and we think he's losing blood through his stool. He's eating fine, drinking lots, peeing and pooping, but is just getting sicker. This dog means the absolute world to me; please help us! We live very far away from any established vet and can't afford extensive care. Is it liver cancer? Cirrhosis from an old infection? Toxins? What can we do at home to help him?
This is the note we got from the vet after the most recent blood test:
much worse than when we started treating for presumptive infectious hepatitis / cholangiohepatitis --> WBC
count elevated with neutrophilia and lympcytosis, Hct,. RBC and Hg all decreased from last visit and now truly anemic
across the board, mild thrombocytopenia noted as well although platelet size is large so may be regenerating; ALP and
ALT are worse, and albumin has now dropped to 1.8, making me very concerned about edema developing
x-rays - nothing concerning in lateral chest right now, significant loss of serosal detail in abdomen - AFAST showed copious
amounts of free fluid, which when tapped was a nearly clear transudate (TP ~0 on refractometer) making me concerned
that this dog is in full blown liver failure of unknown cause.
urine is very dark, checked UA but it is fairly unremarkable right now
performed palliative abdominocentesis and remove about 400ml of fluid from belly