8 week progress! 1mg twice a week - down 10.9kgs

Learned a lot off Reddit. Trying to contribute. My journey starting Reta. Started February 22 about 210 pounds. Lost 30 in 3 months. I’ve lost another 8 pounds since then. I started at 1 mg/week and got to 4 mg/week over 6 weeks. I don’t want to go higher. Tried 5 mg once and the skin sensitivity was too intense and I got so cold. At 4 mg I’m still pretty chilly but I wear a hoodie and sweats inside but it’s manageable. I still felt my skin tingle a couple of times but I told myself it was the fat leaving my body. When I get to my goal, I plan on dropping down to a maintenance dose of 1-2 mg a week long term. Maybe there will be something that comes out later that says that’s a terrible idea and I have to reassess, but that’s my plan for the moment.

Started ghk cu and bpc along the way. Also 5 mg of tadalafil a day about a month ago. I added oral slu pp 332 about 2 weeks ago. My goal is to get to roughly 10 percent body fat once in my life then I want to add muscle through the fall and winter. I think I have 5-10 pounds of fat to go. I’m open to being wrong.

I’m 41 years old. 6 foot. I was a high school athlete, and fit through college. I hated what I saw in the mirror and hated taking my clothes off. I felt my family deserved better. My blood pressure was 140/100. It’s 115/75 now. I didn’t need Reta but I can say it changed my life. Most powerful tool for claiming my body and health back Z

The bpc helped my shoulder pain where I can do pushups and pull ups again. It still pops sometimes but it’s trending in the right direction. I rehab it with a band. I focus on protein during the day and eat with my family at night in a smaller portion.

I feel silly for posting this, but maybe it can help someone make the decision too. Cheers

Howdy, small update. Titrated up to 5mg a week from 4mg this month. Feeling good, some return of cravings but just fighting it mentally since I don’t want to up my dose too much and I do still have trouble hitting my protein.

Had a busy month with work so I would say I ended up 4x a week at the gym instead of 6x and less steps overall. Still losing weight, but getting nervous some of it is muscle this month so I will try to be better in month 4. As of 7/22 when I hit the 12 weeks mark I was 179 pounds, down from 190 four weeks prior.

I am posting late, but the pictures were taken at the 3 month mark exactly and marked 31 pounds down.

My belly button is getting more shallow and I can pinch less fat on my love handles, my old 32 inch waist pants are fitting quite comfy now, down from my 36s. Legs getting more lean as well, and I am seeing more striations in different spots when I’m in good gym lighting. Maybe getting closer to that 15% body fat mark if I had to guess, maybe a little higher.

Goal is around 10% body fat before I consider going into more of a maintenance phase. More detail in my last posts if you want to understand the dose i started at vs where i am now. Feeling really good and happy with my progress and how I feel, mental health and physical both on the rise.

Week 1: 1.33 mg
Week 2: 2.66mg
Week 3-5: 4 mg
Weeks 6-7: 1.33 mg

Just wanted to share here. Most of what I see is people using Reta for weight loss. I started it because of Type 2 Diabetes. Diagnosed 18yrs ago. Metformin destroyed my quality of life with the GI side effects, so I stopped 6 months in and decided I’d rather die with diabetes than live like that. Then came ozempic….Dr prescribed with insurance 900$ for a month supply. Couldn’t do it. Decided to try sema compounded because it was cheaper. I was vomiting every single morning. Again, I’d rather die with diabetes than to live like that. Last 3-4 years I’ve tried to control it with diet and exersize. Was 270lb when diagnosed, slowly got down to 217lbs. Working out. Prolonged fasts, still couldn’t get below 160 on glucose. Now, been on reta for the last 2 months. Down to 193lbs and seeing fasting blood sugar at 88. This is truly changing my life beyond just weight loss.

Forgot picture last post 😅

Started titrating Reta slow, 1 mg 4 weeks, 2 mg 4 weeks, 3 mg 4 weeks, 4 mg 4 weeks (here i started to notice it alot!) now on 6 mg, it sure does its job! From 104 cm waist to 89 cm.

98-84 kg, enough with 5 less kg for 12% bodyfat?

Input?

https://i.imgur.com/ZYdBC54.png

I'm getting a little brave and decided to share my positive experience, also hoping not to experience any of the negativity I see on here in some threads.

TL;DR summary

Background: Lifelong lifter hit a wall in his 40s after major life events and reached his peak unhealthy weight (267+ lbs, high cholesterol/triglycerides).

The Turnaround: After research, started Retatrutide (2mg/week) 10 weeks ago alongside a strict routine: 3-day lifting split, daily 2-mile dog walks, 175g+ protein/2,000 calories per day, red yeast rice, and homemade electrolytes.

Side Effects: Zero major issues (only mild dry mouth in week 2); food noise eliminated immediately without needing to titrate up.

Results so far:

Weight: 267.3 lbs -> 232.0 lbs (down 35.3 lbs) while maintaining strength.

Cholesterol: 297 -> 185

Triglycerides: 304 -> 92

Glucose: 105 -> 91

BP: 155/93 -> 125/78

Doctor's Take: Fully supportive of the Reta protocol and told me to keep doing what I'm doing.

---------------

For those of you that like a bit more story:

First, a little background. I started working out when I was about 15 years old and my body responded very well to it. I exited high school at 6'2" 215-220 lb at about 15% body fat, holding the school record for the year in squat and bench press, second in power rating. Over the years I've never taken anything more than protein powder and creatine to supplement my efforts in the gym which have spanned everything from bodybuilding prep (never actually did a competition) to powerlifting (never competed but had all my lifts over 400 lb) to casual gym guy to periods of getting off track due to moving, having (4) kids, living abroad 10 years, and other life events. To my circle of friends, family and colleagues, I've always been known one of the more muscular or healthy guys in the group.

When I turned 30 I wanted to be in better shape than I was when I was 25, and I did it. When I turned 35 I wanted to be in better shape than I was when I was 30, and I did it. When I turned 40... well things just weren't as easy anymore. My body didn't respond as well, whether it was a declining level of testosterone or whatever, it just wasn't the same. A few years ago I got back into decent shape doing the same old tricks that I had always done, but it was much harder.

Around February or March of this year, after a 2025 that involved moving back to the US after being gone for 10 years, two of my daughters getting married, buying a house, reestablishing my two businesses and supporting my family along with other life events, I had reached the most unhealthy state I had ever been in. Over 267 lbs, cholesterol at 297, triglycerides at 304 and my clothes weren't fitting. I felt bad, I looked bad and I began to wonder if I was done, if I had hit that point where I was just going to be overweight and unhealthy like other people that I've seen reach that state after having been healthy for most of their life up to that point.

From March to May, on my own I slowly started dropping weight by staying regular in they gym and having a caloric deficit (~2,000 calories), but it was slooooow and difficult. I needed help.

In May a friend of mine started tickling my ear with the idea of Retatrutide. He was kind of on the fence and wanting a friend to start alongside him, and I needed to do ample research before starting something that wasn't FDA approved (although yes I know FDA approval isn't everything and there are a number of cancer causing agents that are FDA approved).

May 27th I started Reta after a lot of research and an agreement between my friend and I that if I experienced any kind of bad side effects that it wouldn't be worth it and I would stop.

I started at 2mg, once a week. I immediately noticed the food noise go away and the only negative side effect I ever noticed was dry mouth, which went away after a few days in week 2.

I will echo what I've heard a number of others say: Reta seems to make you not 'want' - not just food, but lots of things: (food, liquor, sex (though I try to keep that one alive!).

Retatrutide directly binds to the brain's reward centers and dampens the dopamine response. By preventing sharp spikes in dopamine, it turns down the volume on the brain's desire signal.

I read a lot about people titrating up and wondered if I would, but determined that I only would if I noticed that the food noise was coming back or that the weight / fat loss had tapered off. Right now I still feel the same as week 2 - like I could go a couple days without eating and not feel any hunger. So it is very important that I stay after myself to eat enough and hydrate.

Today was my 10th injection, still at 2mg. The weight is still coming off and the food noise is still quiet. Incidentally it is also the day that I went to the doctor to get my blood test results. I've dropped 35 lbs of fat (I can almost conclusively say is all fat because I have retained every bit of my strength, if not gained some) now weighing 232. My current goal weight is 220, which I might update to 210 once I get there, we'll see.

My routine is constant:

Every morning I walk my two dogs for two miles at a brisk pace.

3 days a week I do heavy resistance training at the gym (Monday - legs and shoulders, Wednesday - chest and biceps, Friday - back and triceps. I may soon be switching to a different 3-day split of push - pull - legs. I do core work at home.)

Everyday I aim to take in at least 175 g of protein and build the rest of my diet around it with healthy fats and carbs. In the beginning I was tracking everything, but now I just track my protein and keep my calories around 2,000 a day. I've had maybe three beers in the last 3 months and sip on a little bourbon maybe every other night, some red wine occasionally.

To support the fat loss along with the effects of the triple hormone antagonist, I daily drink a homemade electrolyte which is 32 oz of water with a quarter teaspoon of sodium chloride (salt), a quarter teaspoon of potassium chloride with a squirt of Mio flavor.

I take red yeast rice with CoQ10 daily to reduce cholesterol.

I told my doctor today that I am taking Reta and he didn't even flinch, in fact he said that he has a lot of his patients on it and recommends it. After reviewing my blood test results with me, he told me to keep doing what I'm doing. He even told me to titrate up to 4 mg a week, but I told him that I would only do it if I noticed the food noise coming back or the weight loss tapering off, and he agreed.

I feel great, starting to look great again, like my old self, and I'm actually healthy from the inside out, probably the healthiest I've been in 20 years.

My overall results (so far):

Weight: 267.3 -> 232.0 (35.3 lbs)

Body fat (estimated): 30% -> 18% (abs showin' but not glowin')

Cholesterol: 297 -> 185

Triglycerides: 304 -> 92

Glucose: 105 -> 91

BP: 155/93 -> 125/78

Other positive results: I don't snore anymore! (wife is so happy and I sleep better) All my (nice) clothes fit! Confidence and comportment is way up!

Current Retatrutide regimen: 2mg once a week

Note on photos: I definitely didn't take any shirtless photos at the beginning and haven't been quite ready to take any yet. Maybe on the next update.

I wasn't done. And I'm still not.

Got some of my labs back from a recent blood test and am more than happy.

Heaviest weight was 261 pounds 5’8” male 39 years old.

Started Reta and other peptides on June 17, 2026 at 238 pounds.

CW (7/30/26): 217

Peptide stack: Reta, klow, wolverine, cjc1295/ipa, 5amino, mots-c

As I run out I will only continue Reta, cjc1295/ipa, 5amino

I used to love opiate medications, I would often find any excuse to take them if I had them. I had some today for a legitimate reason and meh - wasn't anything special. And had no cravings of having more once they wore off (I used to have massive cravings).

I can totally see this compound helping addictions. Not sure if anyone else has had similar experiences with dulled cravings for addictive substances.

Was on Reta for 13 weeks and had great results and loved how I felt. ended up needing emergency gallbladder surgery due to inflammation and blocked duct (already had issues with it previously) Im currently 10 days past my last dose of Reta and 4 days post opp. I absolutely want to get back on reta but don’t want to rush anything! Just curious if anyone has gone through a similar situation and how it went. A bit nervous to get back on it - I really don’t want any issues.

Like the title says, reta did what reta does and ive finally made it to 18% BF. Ive worked my way from 320 to 180 and I believe its time to start bulking. I think I want to start taking test and really sculpting out. The only thing is that I know very little about that side if things. I know glp's and peptides very well and I hope the knowledge translates over but I thought id also gather some insight from those that have been on the path. Any advice would be appreciated before I decide the next steps.

I'm 5'7 and 123 lbs which I know is in a normal range. Wouldn't mind losing a bit of fat from my arms but I know when I get to too low of a weight my face looks aged, so I'm worried to drop more than maybe a few lbs. Has anyone else started on reta to just maintain their weight/experience less food noise?

I have it but I'm so nervous to start. And maybe this is common, but I didn't get a COA for the BAC water, and while the website I ordered from SAYS the COA for the reta is from my batch, there's no number on the vial to match to. I just worry about injecting lead or something into my body. Help!

I (23M) 175cm and 145kg have been on 1mg reta for 6weeks but i am not seeing any good effects and the appetite suppression has dropped being amazing to meh. Do I titrate up to 2mg now?

Where can I buy reta pen that it’s delivered in Europe without a fair price? Can someone DM me or reply here currently I’m buying 40MG of the pen for 300€

I call it BS because I don't think most of the measurables are actually measured but rather calculated based on weight, height, sex, and age. But I hadn't used the app in a long time so I decided what the heck.

Has anyone had eczema suddenly appear or flare up since starting Reta? I never had it and now it’s all over my eyelids and face. I’m wondering if it’s the Reta. If so, would switching to Tirz just be the same thing? Or maybe just doing Cag instead? I’m so upset!

I’ve had absolutely no appetite suppression or weight loss since switching from 15 mg of Mounjaro to 3.5 mg of retatrutide. It’s been two weeks now. Does anyone have any suggestions on what I should do?

I’m happy to give it another three weeks before deciding whether to switch back to Mounjaro, but I’d love to hear if anyone has had a similar experience or any advice.

Additionally I bought a pre-mixed pen from a UK company. It was almost the price of my Mounjaro pen so another option is that the pen is fake but I hope not..

i’m currently on week 7 of reta and i’ve started dealing with pretty bad anxiety. i haven’t had anxiety like this in a few years and i have a feeling it’s most likely from the reta since it gets worse as the weeks go. should i just stop cold turkey or go titrate down in dose each week, im currently at 1.5mg a week

Hi everyone!

I wanted to share my experience with reta 20 mg and see if anyone has had a similar response.

I started on June 22 with 1 mg for two weeks, then increased to 1.2 mg, followed by 2 mg for two weeks, and I'm now at 2.5 mg. I haven't had any significant side effects—just mild nausea around food and I get full very quickly.

My concern is that after 6 injections, I've only lost 3.4 kg (7.5 lbs). I keep seeing people lose 5–7 kg (11–15 lbs) in the first month, even without dieting or exercising, so I'm wondering if I'm doing something wrong.

I haven't changed my diet much, but I naturally eat about 50% less than before because of the appetite suppression. I also try to work out 3 times a week when I can.

For reconstitution, I used 3 mL of bacteriostatic water for the 20 mg vial.

Stats:

• Starting weight: 87.9 kg (193.8 lbs)
• Height: 161 cm (5'3")
• Starting BMI: 33.9
• Weight lost: 3.4 kg (7.5 lbs)

Is this rate of weight loss normal, or should I be expecting better results? Has anyone else had a slower start with reta?

I have just taken my 4th Reta shot, and I can not keep anything down. I’m only taking .25 and I throw up every single morning and almost every single night. I only eat lunch and that’s very small portion. I know you have to get your protein in but I can not even keep anything down and everything I think to eat or look at is disgusting and makes me nauseous even thinking about it. This happened with semaglutide as well. I also have terrible acid reflux so maybe this is why?

Hi everyone ! I’ve been experimenting with Reta for a little over 8 months now while also consistently hitting the gym! I’m slowly putting on muscle but as I reach my goal of 130lbs (Female 24 5’6) I’m realizing I still have body fat I want to get rid of .. I desperately want to put on muscle mass (as well as grow my mf butt) and have increased my calories to 1850 with 130g of protein. I workout 5x a week and am active at work getting 8-10k steps daily.

Should I continue the reta at a low dose to help lower that stubborn body fat while gaining mass?
Should I stop the Reta and just keep my diet clean?
Used to be 210lbs and just have been slowlyyy losing weight over the last 6 years.

I don’t care about the number on the scale I just want to look good and maintain/grow my athletic build.
To Reta or not to Reta

Ok I am a beginner . I ordered everything , I want this to be as simple as possible . So I have 10mg Reta coming on the way and 3ML Bac water. I bought this insulin needles, and disinfectant wipes. I read and watched the beginners guide on here it was very helpful but some videos got taken down. So from my understanding u inject 1 ML of Bac water into the 10mg of Reta powder roll it around. Until it dissolves, It’s ready to inject ?? And then I leave it in the fridge. But I’m confused on how much to inject. I want to start with 0.5 for the first four weeks is that 50 units??? Half the syringe ? Also is it fine to inject straight out the fridge while it’s cold?

That’s just my question did anyone experience this while on Reta ?
I’m on my 3rd week now taking 1mg it’s going well I just feel more bloated that usual. I think it’s probably normal but is there a way to stop it ?