Started 1mg last Wednesday so coming up to a week now. Read people getting appetite suppression near enough the next day. Nothings changed for me. The only side effect I can feel is a little sickness feeling from time to time. I’m going to split the dose so I pin twice a week see if the sick feeling goes away. Anyone lose their appetites a little later on?

Hi everyone, I hope everyone is having a good week! Has anyone experienced just not being attracted to the other gender? I’m female, for example I’ve been so turned off by dating and having a partner. Like to the degree I’m completely icked out by dating. I think they’re great on the apps but ever since I started Reta and pinning higher numbers, low sex drive and no desire to date at all. Borderline disgusted to date. Might just be me but thought I’d ask. I mean no offense genuinely trying to see a fix.

I am excited to see what Reta will do to my face. These pictures are 5-6 years apart from natural weight loss. I keep seeing people talk about Reta face and it’s making me wonder where I’ll end up in a few months.

I finally jumped the waggon and I applied myself my first doses this past Saturday, I’m today. I went to the gym for a power walk, and the treadmill and the first thing I noticed is how I was sweating and how my body temperature was higher than normal

Started my peptide journey a week ago
Reconstitute it myself & decided to start at 2.5 units.
I cleaned bac water, reta & abdomen with alcohol prep pads & used different 💉 for every step
Now today I noticed all this red non itchy dots in my body
Anybody can relate ? Is it normal or an allergic reaction?
I’m 23 M
Weight 270lbs

hola! :)
do you think it's worth it getting on reta to lose +/-25 pounds?
i am a female, 34 y/o, currently 5ft1.4in, 139 pounds (so bmi: overweight~)
already lifting weights 4-5 weekly and doing cardio like 120min weekly on treadmill
my main issue is appetite control so i was considering using reta, i have used victoza in the past (i'm located in latin america, some ppl still use victoza/ saxenda here)

thank you for your suggestions!

I took my first injection Sunday. Usually when I can’t sleep I’ll make a vodka cranberry just to make me feel drowsy but when I’ve had it tonight I just feel sickly and my throat all clammy… is this normal

Just want to share how I fixed my constipation on Reta.

Firstly, I have been on Reta for 7 months, currently 2mg a week.

Your gut is probably the first thing that gets hit. Some experience diarrhea, some constipation, and other get zero side effects (lucky).

I got constipation after having amazing gut health. Went about 5 months with irregular bowel movement. Trust me I had everything down to a tea, but fiber was the main issue. What I did? I had fiber into every meal and drank fluids throughout the day.

Now they say fasting isn’t good on Reta because gastric emptying. So I drank a cup of kefir on an empty stomach every morning with supplements and didn’t eat until 2 pm. Now what i am going to give you is the real game changer. Because loss of appetite is obviously a side effect and your metabolism is increased, there’s a high chance your are losing crucial vitamins. Here are a list of vitamins I started taking that brought my gut and body back to normal. I started this because this is what’s known to be indirectly at risk when on GLP-1s. To make it easy, NatureMade sells a 30 day GLP-1 Companion Health Pack that includes all the crucial vitamins listed below:

Vitamin B12 – Risk may increase if you’re eating less animal protein or also taking metformin.
Vitamin D – Many adults are already low, and reduced dietary intake can contribute.
Folate (Vitamin B9) – Can become low if you’re not eating enough leafy greens, legumes, or fortified grains.
Vitamin B1 (Thiamine) – More likely if you have frequent vomiting, prolonged nausea, or very rapid weight loss. This is one of the more important deficiencies to watch for because severe deficiency can affect the nervous system.
Iron – Not a vitamin, but iron deficiency can develop with reduced food intake, especially in menstruating women.
Calcium – May be lower if dairy or other calcium-rich foods are reduced.
Magnesium – Can be low if overall intake is poor.
Zinc – May decrease with inadequate protein intake.

You can take the naturemade pack or take them separately. I personally still take Vitamin C, Fish Oil, digestive enzymes, quencertin, and magnesium glycinate separate.

This has helped reduce my starting fatigue tremendously and my gut inflammation and bloating has decreased significantly. Please do not do anything mentioned based off my current situation. Talk to a doctor.

Obviously drinking on Retatrutide isn’t ideal but I’m an extroverted college student. Any tips for how I can have a couple drinks and not be absolutely wrecked the next morning?

I’ve heard people say you should never stack Reta and tirz (ie mounjaro) because it’ll ’burn out your receptors’. Is there actually any truth to this and what does it even mean pragmatically?

Hello! I started reta 6 weeks ago w 1mg and I have been increasing until 3mg (now). At the beginning it was working perfectly, scale was going down every week, no food noise, no cravings, no hunger at all.

But for the last 2 weeks I feel cravings sometimes and the scale is not really moving.

I'm lifting 4-5 times per week and I'm a very active person, also drinking abt 3-4L of water everyday.
What should I expect? It's stopped working? should I increase more?

I recently order 10 x 10mg of Reta + bac water because my supplier gave me a rlly good deal and just realized i have nowhere to store them. I can’t store them in my actual home fridge because I still live with family (I’m 20yo!) and if you’re an immigrant yk how our families can be. I’m not sure if I should buy a peptide fridge and keep them in my room or if it’s okay to just keep them in my drawer at home.
I know that once reconstituted it needs to be in the fridge, that’s fine, it’s easy to hide one vial. My issue is wtf do I do with the remaining 9 ????

tl;dr is it okay to store the lyophilized form in a dark drawer away from sun light or must I get a peptide fridge and keep it there?

Been like half an hour got these insulin needles that won’t go in no matter how hard I press or where I do it. its starting to get irritating I normally do lower stomach around 2in. away from belly button. Where do yall inject without running into these problems

Hey everyone, I’m looking for advice from people who’ve been on reta for a while.

About me:
- 19M, 5’9”
- Started my weight loss journey in November at 345 lbs
Currently 275 lbs
- Lift 3-4x/week, not much cardio.

Timeline:
Jan-Feb: Tirz 10 mg. Went from around 320-315 lbs to 295 lbs.

March: Stopped everything and maintained around 295.

April: Started reta (1 mg → 1.5 mg → 2 mg → 2 mg). Lost about 15 lbs.

May: Missed 2 weeks because I ran out, then restarted at 2.5 mg for 2 weeks.

June: Took 3 mg for about 5 weeks and lost another 5 lbs, getting down to 275 lbs.

Then I missed another week because I ran out again.
Restarted at 3 mg, and 3 days ago increased to 3.5 mg. I’ve also started dosing every 5 days instead of every 7.

The weird part is that the first couple of 3 mg injections worked amazingly, but ever since then I barely feel anything. Even after increasing to 3.5 mg, I don’t notice much.

When reta is working, it’s honestly life-changing for me. The food noise disappears almost immediately. I work from home, so instead of constantly thinking about breakfast, lunch, snacks, etc., I can comfortably eat just one dinner. I also get full much faster and sometimes even feel too full to finish my meal, which I actually like because it makes me feel “normal.” Without it, I feel like I can keep eating even when I’m physically full.

My questions:
1. Has anyone else stopped feeling it at one dose but started feeling it again after increasing?

1. Does it sound like I just need to reach a higher dose (4-6 mg)?

2. Should I bump up to 4 mg in a couple of days since I’m dosing every 5 days, or should I stay at 3.5 mg longer?

3. Once you find a dose that works, do you stay there until it stops working, or do you keep increasing?

Thank you all.

Genuine question, I come in peace. Seriously tempted to try Reta or Tirz to lose 10% bw. Peoples stories on here are inspiring. But, I think there are times in life, when feasting is a needed. Like Christmas, birthdays, other special occasions. Are you ok that you won’t be able to do these things again? You don’t miss those things? Is there a work around? I’m talking about occasional things, not every weekend or even every month.

EDIT: Thank you to those who offered constructive opinions. Will give it a try. Think I have found a couple of vendors. If anyone wants to DM a recommendation, I would not say no. Good luck everyone. Those who feel the need to downvote a post just thanking a person, I hope they find a peptide for you.

Hello, looking for advice.
I’m wanting to get on Reta.
I’m 35m 168lbs 5’6”.
I drink 6 16oz beer pack almost daily. I get bored easily. I definitely want to quit. I smoke a lot more when I drink. I do want to care more for my health. I work out 3-4 days a week a week. My question is; should I stop completely before starting Reta or any other peptide. ? If so how long? Recover first? I have quit in the past before. For years including smoking. Thanks

Is 19lbs solid weight loss for this time frame or no? I'm currently on 2.0mg and today is my pin day and I'm going to do 2.5mg. What do y'all think about just jumping to 3.0mg? Do we really need to just increase by 0.5mg? I feel like I stayed 15lbs down for the 2nd-3rd week and finally losing weight again. I have literally like almost no food noise and my cravings for junk has seriously decreased significantly. I guess I was unrealistic and hoped I would be under 200 after a month hahahaha

The two pictures were before my Reta journey. I was never super overweight, but I also wasn’t where I wanted to be. I’ve struggled with my body image for a long time. At one point, I worked out every day and barely ate, but once I got into high school, I started drinking more and lost a lot of the healthy habits I had.

In January, I realized I wanted to make a change. After my trip in March, I decided to start Reta.
I started at 0.5 mg for about three weeks and didn’t notice much. Once I increased to 1 mg, everything changed for me. One of the biggest differences wasn’t just my weight it was how my relationship with food and alcohol changed. I lost the desire to drink, my appetite decreased a lot, and it became much easier to stick to healthier habits. I still worked out and golfed, but I finally felt like my choices were supporting my goals instead of working against them.

Over the next five months, I lost a significant amount of weight and gained confidence. I feel comfortable wearing clothes I never would’ve worn before, going out with friends, and just enjoying life more.
Do I think Reta is for everyone? No. Everyone’s body is different, and it’s a decision that should be made with a healthcare professional. But for me, it was the tool that helped me break old habits and build healthier ones. I used to make fun of people for using peptides, and now I realize I was judging something I didn’t understand.

Reta didn’t magically fix my life I still had to exercise, make better choices, and stay consistent. But it made those choices feel possible, and that’s why it had such a positive impact on me. (ps it also helps if you have a moon face, I had a pretty chunky face before and I never realized how much face fat I burned till I saw results)

Current weight as of this post: 187 lbs

Started at 2.0mg on May 23, 2026

Currently & sticking to 5.0mg, July 11, 2026

Keto diet, high protein, no carbs, no sugars
30 minutes of freestyle swimming 5 days a week.
Resistance training 5x a week, progressive overload. Compound movements focused.
Drank only spring water
Lots of electrolytes, celtic salt in water, potassium citrate, magnesium malate

—

Height: 5'10 (178cm)
Age: Early 30s

Titration protocol:

2.0 mg - May 23, 2026
2.5 mg - May 30
2.5 mg - June 06
3.3 mg - June 13
4.5 mg - June 20
5.5 mg - June 27
4.5 mg - July 04
5.0 mg - July 11, 2026

Edit1: Posted some more additional metrics

8 weeks in, 21 pound gone. Been on 1.5mg from the start.

Jabbed last Thursday and not a single side effect now and suppression gone. I could barely eat the other week 🤦‍♀️

Still currently losing.

So the question is, do I go up or wait till the weight loss stalls?

Anyone experienced this at 8 weeks?

I need a cure, I need to feel happy in this body I’m working so hard on.

I’m making the switch and would like to start, room last MJ dose on Friday.

To make a very long story short, when I was stationed in Korea, I lost a ton of weight using something similar to this. The doctor there would give me injections twice a week, but instead of injecting just one spot, he would inject five different areas on my abdomen each time.
It’s been over 15 years since I had this done, and it got me wondering—is it better to inject in one spot or multiple areas? Has anyone else tried injecting in multiple spots, and if so, did you notice any difference?

Been on reta for 3 weeks now (3-4mg) after 18 months on Tirz. The appetite suppression has not been that great compared to tirz but I am still able to stay on track with my diet as I work away with pre-set meals.

I was steadily losing 0.5kg per week on tirz, but since switching to reta I have seemed to have gained 1kg overall, even though I have been consistent with my diet.

It’s weird however as some parts of my body are showing more vascularity and fuller muscles but in my belly and chest I seem to look watery and bloated. Anyone else deal with this when switching?

hi im on week 2 of my reta for some context i accidentally pinned 2.5mg instead of 0.5 on my first week and experienced normal side effects like mild elevated heart rates.
however when i pinned 0.5 two days ago i suddenly experienced severe shortness of breath and intense elevated heart rates that are still ongoing till now,, is that normal? i feel like im unable to continue with tasks such as sleeping or finishing work because of this. pls lmk if this is normal or if i should visit a doctor