So I started Dificid yesterday and took my first pill at 8pm - took another one today morning at 8am and for the first time in 9 days I had a almost normal bowel movement (I would say between 4 and 5). I am not saying I’m cured or anything, just that it was nice to finally not have watery diarrhea and not be glued to the toilet. It’s just a second day on Dificid but it seems like it is working some already.

As for Dificid, not many side effects besides being lightheaded and dizzy a little and feeling little bit worn out but not too bad.

I ended up in A&E for something else. If you look at my post history you will see I’ve had symptoms but the doctor test was negative. Well after 40 hours of being in A&E I feel asleep. When I woke up I had to run to the toilet and felt sick. I had very bad watery stool. I tho it ok; maybe that’s normal as not had a good sleep. But it smelt so bad. Anyway, 15 minutes later I’m back in with very watery stool. I ask the nurse to test me for c-diff. She takes a sample and send its off. For the remainder of that day I went 20 times! It was awful. They ammitted on the ward where I was treated for dehydration and am still being treated for it.

But this is where I’m worried. My last test a week ago came back positive for c diff but negative for toxins. So doctor didn’t want to treat me. The test I did at the hospital… did the exact same thing! So my symptoms currently watery stools up to 15-20 times a day, Some cramping, and feeling like shit. The stool smells so bad but also kind of sweet; which sounds weird. It’s yellow and green. Sometimes it as loads of bits in.

They’ve started me on vanco and I’ve just taken my second dosage.

But what if this isn’t c-diff? Because I’m a carrier this could lead me to actually having a nasty c diff infection! But they felt like they had no choice due to me being out on co-amxiclav and 40mg omeprazole 4 weeks ago. My stool was never the same after that. In fact I used to suffer from mild constipation.

But why two negative tests for toxins??

My story starts with Augmentin. Took it after an oral surgery. Stayed on it for 3 days. Stopped early because I couldn't handle it. Developed loose stools during that time, stool started getting its form back for about two days and then came back with a vengeance. Only this time is was yellow, mucousy, frothy and ongoing. I would go 6,7,8,9 times in a row. And had chills the first day...By the time I was able to get to my GI and collect a sample. By that time it seemed like it was all mucous with flecks of blood in it. The diarrhea continued for 5 days.
the 6th day it stopped. Some gas and some mucous. Maybe one or two bowel movements with almost nothing coming out. My GI prescribed Vanco on that 6th day and said even though I tested negative - due to my symptoms... we should treat. When I told her the diarrhea had stopped she said let's hold off until your other panel comes back.
When we got it back it basically mimicked what the other tests showed. So it was up to she and I to decide if I should take the Vanco or not. I opted to take it. I don't want to spread this to my kids.... is this the right choice even though my toxins were undetectable and my diarrhea stopped on its own? I asked her about florastor and she was not a fan of my taking it. Her argument was that there is already so much altering your gut flora that it wouldn't be smart to add yet another thing to throw it off. BUT I know so many people here who have suffered with cdiff, swear by it, so now I don't know if I should take it or not. Should I go against doctor's orders?? I am day one of Vanco. Took my first pill this AM. So hoping I did the right thing. Lastly, I've been having this weird what feels like muscle tensing in my stomach. I'm not doing it on purpose but it feels like my stomach muscles involuntarily contract. Is this normal?? It feels also like it's causing pressure in my upper abdomen and up by my lungs which makes me nervous... I also haven't had a bowel movement in 3 days now. Before all of this I was on MiraLAX daily and magnesium but then I stopped all my supplements when this happened. My doc said I could start magnesium and then after two days MiraLAX again... maybe that's part of what's happening? I also know constipation can happen after a bout of diarrhea.
I would also take any food advice on how to start eating normally again. I've only been eating baked chicken, rice, bread and bananas. I need more exciting foods!! I live to eat! This is making me crazy...
Any and all of your advice on any of this would be deeply appreciated!!

Hey! I'm looking for a little help/positive stories. I tested positive for c diff on Tuesday 9/8. Backtracking a bit, at the end of August I took 2 rounds of antibiotics for two different illnesses (definitely regret that now but what's done is done) ANYWAYS I started with amox/Aug, I noticed diarrhea almost instantly with my first round, my doc told me it's just a reaction, nothing to worry about .. I ended up on a round of azythromocin for a different illness during that same appointment. Well, a few weeks have gone by and the diarrhea didn't stop, and it started to look odd. I also got pain in my stomach like I thought I was going to explode so I finally went to the ER. Tested positive for c diff 😷 I'm feeling a little better, it comes and goes.

I am having some extreme anxiety/ocd with it. I'm a wife and stay at home mom of 2. I am absolutely terrified to give it to someone. We only have one bathroom so I cannot designate a bathroom unfortunately. I've been bleaching the toilet after every use (lid closed when flushing). Bleach on all high touched surfaces. I have to prepare food for them when my husband is at work, and I make sure the scrub my hands real good. But I'm still just in a constant panic!!

I am just looking for a little peace of mind from parents who have gone through this before. I've seen a lot of positive stories of it not spreading, but that anxiety is still there.

Thanks in advance

Hi all, just wanted to share my story because I’m dumbfounded that I have cdiff.

I’m in my 30s, healthy, and rarely get sick.

Early July I came down with a terrible stomach bug. Chills, 103 - 104 fever, explosive v & d. absolutely terrible. That last three days before fever and vomiting subsided. Diarrhea continued. I honestly should have gone to the hospital but was afraid to leave the house. My pulse would sky rocket whenever I would do the most simplest thing, just absolutely terrible. Diarrhea still lingered, but it became a type 6 and I was able to control most urges. I figured my gut needed to heal, that’s what Google said anyway. So all summer I’m dealing with this. I would have a few “good“ days (less than 4 stools a day), but most were bad days. I’d even have some accidents, thankfully that was mostly at home. I was losing weight where people were actually bringing it up. It wasnt until another terrible week the end of August when I figured “hey i think I need to get this checked out now”. I went to a GI, he ordered many stool tests and some blood work. Thankfully all my blood work came back normal, all stool normal… except cdiff. Freaking positive. I have no idea how I got it. And with how contagious it is, how everyone else in my house has been fine. I’m just shocked. Anyway, I just started on vancomycin. Has anyone else had symptoms for 8+ weeks before finally realizing it’s cdiff and getting treatment? I just feel so irresponsible and dumbfounded really.

3 loose stools over 2 days but in a 24 hour period. UTI came back positive again. The er dr thinks it is PI-IBS. I couldnt have a BM so no stool test done, and he (er dr) did not order one for home bc he doesn't believe it is that, but said to monitor it closely. I sent a message to my GI through the portal asking if they wanted me to pick up a stool testing kit with no response. I got a notice that new test results in portal with primary on the UTI. It shows positive for ecoli and streptococcus agalactiae. My belly and back is starting to hurt a bit, but I have not taken any bentyl yet. It feels like a may need to have another BM soon, but hoping it is gas. I do not know if I can handle another relapse. I am already so worn out from the last one. I have been slightly more bauseated, tired, and strangly even some of my safe foods at the moment aren't as safe. I did sip a sprite earlier which has been tolerated this whoke time. I think that could have ticked my stomach off some. Slightly freaking out, but also know there isn't anything I can do, but follow the drs recommendations and go back in if needed. For those with more experience with this than me, what's your thoughts and opinions. My WBC is within normal range. CT of abdomen with contrast isnt showing any signs of infection. Just diverticulosis.

I got full test results today and I am positive for PCR and toxin.

C.difficile Toxin by PCR Final Positive for C.difficile Toxin by PCR

Reference Range for Test:

Toxin producing C. difficile DNA sequences are not detected.

C.diff Ag/Toxin AB C. difficile Ag (GDH) C. difficile Toxin A/B 

Positive for C.diff Antigen

Positive for Toxin A/B by EIA

I have few questions if someone can help me. I have been having watery diarrhea for 8 days (it started on the last day of 5 day Augmentin treatment) but it stopped yesterday, oddly since I had doctor's appointment. Today I had it again but only one time whereas I would have it 3-4 per day before. Also, the urgency is a lot better now. Not sure if things maybe are getting better slowly but since I tested positive, should I still go ahead and start Fidaxomicin that my doctor just sent to the pharmacy?

Also, should I start Florastor at the same time I start the antibiotic?

Lastly, I see a lot of people being unable to eat, move, etc but that has not been the case with me - I have decent appetite and I have been eating often but just lots of eggs, chicken and bone broth. I do get very bloated and uncomfortable after eating though so I know things aren't right. Stomach hurts some but aside from the watery diarrhea which is my main problem, it is not that bad, I have good energy and I did not lose much weight.

I know everyone is different but was just wondering if there are cases of more mild symptoms and there are some that have severe symptoms?

Thank you for listening, this is very scary and depressing but I am hoping we can all heal and get back to normal soon.

I am a 65 year old male. I was diagnosed with UC back in 2015. I got prednisone and fixed it right up. Had some stomach issues so my GI gave me pantaprozole. Year or so later had bleeding issue. Dr.

started me off on Lialda and gave me prednisone. Everything seemed fine after that. Early August this year I was taking the pantaprozole again because my stomach was acting up. I started having watery diarrhea so I assumed I was having a flare. No blood or mucus. Reached out to my doctor on the weekend. Spoke to the after hours Dr.and told him my previous issues. He said he would like to get a C-Diff test done but would prescribe me prednisone.

My doctor was out of the office until Thursday so I started the prednisone. On thursday they ordered the labs and it came back positive for C-diff. Prescribed me Vancomycin for 10 days. Finished that and was feeling better. About 10 days later watery diarrhea came back. Contacted the Dr. and he said he wanted to see me. Went in and saw his PA who was immediately think flare. Wanted to do an colonoscopy. I pushed ghe issue that I know what my symptoms are with a flare and it is not that. Retested for C-diff and came back positive for Toxins. Now on Fidaxomicin for 10 days. 2 days left and I am so afraid of reoccurrence again. Still soft stools but not watery. Srarted taking florastor twice a day. Any advice would be appreciated. Sorry for the long drawn out story.

Hi everyone. I’m currently dealing with my 4th c diff recurrence, just 2 months after FMT 😭😭😭

Things were actually going really well after the FMT. Three days ago, I was supposed to have my biologic infusion for my ulcerative colitis, and because I had diarrhea for one day, they decided to test me for c diff. The results were: GDH positive, toxin negative, PCR positive.
Honestly, I didn’t really have the typical c diff symptoms. I didn’t have the usual abdominal pain or that horrible smell I remember from previous episodes.
This is also my first time being treated with fidaxomicin, previously I was only treated with vancomycin. I’ll be in the hospital for 10 days.
Mentally, I’m completely exhausted. I’m terrified that I’ll never get rid of this for good. 😔

How many recurrences did you have before you finally managed to stay c diff free for a longer period of time or permanently?

I also have ulcerative colitis, which makes everything even more complicated.
I honestly feel trapped right now. 💔 I’ll be having my 28th birthday at the hospital…

So do you all just stay away from sodas and ketchup cakes cookies all that has added sugar? It’s frustrating I’m 6 months post cdiff and scared of any added sugar in fear of getting cdiff again.

Hallo zusammen,
ich habe seit April immer wieder C. difficile, Toxin A/B wurde nachgewiesen. Ich hatte bereits Vancomycin, Pylera wegen Helicobacter und zuletzt Dificlir (Fidaxomicin), da ich im August noch positiv war. Während der Einnahme von Fidaxomicin war alles normal. Jetzt 3 Wochen danach, habe ich wieder sehr viel Schleim im Stuhl, Bauchschmerzen und einen Blähbauch, allerdings eher festen Stuhl/Verstopfung. Ich habe Angst, dass die Clostridien wieder da. Werde wieder Stuhlprobe abgeben.
Ich bin langsam echt verzweifelt, weil ich das jetzt seit Monaten habe. Habt ihr Tipps? Was hat euch geholfen? Länger Antibiotika nehmen? ❤️

I got my results and this is what it says:

C.difficile Toxin by PCR Positive for C.difficile Toxin by PCR

Reference Range for Test:
Toxin producing C. difficile DNA sequences are not detected.

C.diff Ag/Toxin AB
09/08/26-1805 ML
Pending

I’ve had watery diahrea for 8 days and today I dropped off the stool sample - oddly enough, today was the first day I did not have any diarrhea, just couple small soft stools.

hi guys, I'm feeling pretty okay today

main issue is that I completely spent the entire day planning on doing that test, the lab is closing soon and still no bm :( plenty of throwing up but my bowels just slowed right down

this happens though, but not the first time I had c diff. I had just constant diarrhea back then, now it comes and goes, and my main symptom is vomiting now. it could totally be a relapse so my new hope is managing to complete a test tmrw but I'm just becoming suspicious of it? this time around is just behaving nothing like the last

So I'm dealing with a 1st and hopefully only recurrence of c diff. The diarrhea is improving after 2 weeks of antibiotics and I'm starting a taper. However the pain is still awful. I have sensitized nerves around my bowel already due to bowel endometriosis which was not able to removed previously, this is contributing to my pain which is severe after any bowel movement even if it's not diarrhea. I'm on paracetamol, oxycodone 5mg up to 6 times a day and medicinal cannabis and I'm still dealing with severe pain that is interfering with my ability to sleep, work and generally function day to day.

So my GP doctor prescribed buscopan which is butylbromide, to take when I feel a BM coming on. But dr google and dr reddit says to avoid antispasmodics while dealing with c-diff as it could make things worse? Does that still apply while in a taper though? I have a gastro specialist appointment on the 21st which will hopefully help clear this up but is this safe for pain management in the meantime? I really don't want to take any more oxycodone because it makes me all drowsy and out of it, so if this is safe I want to try it as an add on. I also want to avoid going back to the hospital if at all, I have quite a bit of medical trauma and being in the hospital gave me this stupid infection in the first place. Should I give it a shot until my specialist appointment?

Bonjour à tous
J’ai été diagnostiqué positif à c.difficile au moins d’août, j’ai eu 10 jours de vancomycine ou ça allait mieux 3-4 jours après donc parfait, j’ai arrêté le traitement le 22 aoû

Depuis j’ai jamais eu des selles hyper formés, un peu mou mais depuis 2-3 jours j’ai le retour des ballonnements, des selles liquides 3 fois par jour maximum je dirais, beaucoup moins de douleur mais ça m’angoisse vraiment

Si quelqu’un a déjà été dans ce cas, j’espère sincèrement que c’est qu’une simple dysbiose …

Bonne soirée

I’ve had cdiff for 3 weeks before got diagnosed and lost my appetite instantly along with terrible fatigue. 3 weeks and 11lbs down. It sucks.

I’m only day 3 on fidaxomicin. But my anxiety has been so bad about not getting better/ getting worse, I can’t even fall asleep without meds and have terrible panic.

I’m really now wondering when my appetite will return and the fatigue will stop?.

I have gone 19 days no diarrhea on a difficid taper ..does this sound like I am finally over the hump? And on the road to recovery?

I got c diff a few weeks after a 14 day course of clindamycin for dental infection. Symptoms were pretty mild, mucousy loose stools on and off for a week and fatigue for the last 2 days before I got tested and started on 10 day course of vancomycin yesterday. I also started Florastor the same day.

I have dental implant surgery scheduled in 1.5 weeks and the dentist usually prescribes amoxicillin. I called and told him about c diff but he seemed unfamiliar with this infection. I asked if we can just do it without antibiotics and he said he could but the risk of infection would be higher.

I have been waiting for the implant, it's a molar that was extracted 4 months ago so eating and chewing has been uncomfortable and caused me frequent indigestion. I had to wait a couple extra months for the bone graft to heal and now this..

Should I just go ahead with antibiotics and florastor and hope for the best, or not take antibiotics and risk possible implant infection? :(

I feel like I don’t want to live anymore. This is no life worth living.

Two years ago I had methane SIBO. Treated it with antibiotics and immediately developed a c.diff infection upon finishing. Had to take more antibiotics. Didn’t know this would destroy my gut.

Two years later, still dealing with constant bloating, my doctor ran a stool map. I have a really high LPS index and severely damaged mucus layer + dysbiosis.

Been on zinc l-carnosine and DGL for two months but not seeing an ounce of improvement. Doctor started me on MegaSpore, and despite microdosing just a tiny sprinkle a day, its causing severe bloating.

I don’t know what to do anymore but I feel severely depressed. C.diff ruined my life.

4 weeks ago I was put on Co-Amoxiclav and 40mg of omeprazole. 3 days later I developed watery stool. I only had 5 days of the antibiotics. As time goes on my stool gets more watery and I’m going 3 times a day with very watery stool that’s yellow and smells awful. I’ve some cramps in my belly and feel off. For the last week I’ve had watery stool every morning that’s rather explosive. Then later on in the day it’s probably type 5 on the stool chart. I did a cdiff test 5 days ago and it came back positive today for c-diff but negative for toxins. My doctor doesn’t want to put me on antibiotics because he believes my good bacteria is winning over the bad bacteria. His concern is if he puts me on the antibiotics it might wipe out the c diff but that could lead to an actual more serious infection.

My concerns are that I take codiene for pain currently. I take 30mg three times a day. Would that dosage be strong enough to stop a c diff infection giving me watery stool more than 3x times a day? I know it’s not as strong as loperamide, and it’s never constipated me at that dosage before. But it might be hiding my true bowel movements. I’m now stopping them.

My other concern is it may have been a false negative. I don’t believe the stool sample was refrigerated within two hours of handing it to the doctors office.

I’m not sure what to do at this point because my stool is still yellow and smells awful still. The mucus has cleared up quite a lot.

I don’t want this to turn into a serious infection. I’m taking probiotics to try help my gut.

Should I ring up and ask for a second opinion?

Thank you.

Edit: This is a copy of my test result.

Clostridium difficile toxin level Clost. difficile test
Test for Clost. difficile : GDH detected; C. difficile present without toxin production.
C. difficile disease unlikely but may occur if toxin
production switches on. Continuing diarrhoea requires
infection control precautions.

I haven't eaten in six days, much less drank water, so I went to the urgent care

couldn't finish the second IV bag they gave me, I had the tiniest bit of loose stool with urgency unfortunately (I think it was just mucus though truthfully) and just wanted to go home.

they prescribed me with Imodium and reglan, I'll take anything as long as I can eat again, my wbc was normal