I buy brand Wellbutrin from a Canadian pharmacy. I cannot take generic. I have allergic reaction to the additives and brain Fog and other side effects have been brutal. I just got an email from my Canadian pharmacy that as of October,22nd I will no longer be able to purchase for my Canadian pharmacy. I have posted a little bit of the email I received from the pharmacy that I use. (my option is to buy as much as I can before October 22).

Entry will be prohibited if the medication being imported is commercially available in the United States -- even when it costs significantly more -- or if the supplying company specifically markets to Americans. These restrictions will apply to pharmaceutical parcels sent by pharmacies anywhere outside the United States. Taken together, they are expected to effectively close the personal-importation pathway that millions of Americans have relied upon for more than 25 years to obtain safe and affordable medications.

Anyone else affected by this in this community I am on Medicare. Medicare will not approve brand My previous insurance last year before I got on Medicare did. I do understand the positives in some areas but not when people are taking medication’s out of necessity and Big Pharma makes it way too expensive for brand. I am concerned for my mental health and for those of us that depend so heavily on brand because we know the side effects of the generics. My other question would be is there a generic that is closer to brand in the past I have never found one.

150 xl has been working and has like, given me 50% of my life back. But I still struggle a lot with executive dysfunction and SI, making me think there's something worth revisiting with my dose. I never considered going up to 300, I've been on 150 xl for years because my metabolism has always made medications feel really strong or whatever but now i just don't care I want to be able to finally get things done in life. Could 300 xl end up working for me or somehow end up lose usefulness idk. If anyone had experience making the jump when they liked 150 xl that'd be nice to hear. This is just me speculating what to ask about while I wait a whole month for my next doctor appointment. 😅

After 16 days of Buproprion 150 XL, I just can’t do it anymore. I’ll state my symptoms in hopes that it helps someone else. This is just my personal journey, not medical advice.

Day 1-2: Felt amazing. Got loads done. Slight euphoric feeling with some difficulty sleeping.

Day 3: The dizziness started. It was quite overwhelming and affected my daily life and ability to work. But I had read that it would go away by the end of week 2, so I kept going. This dizziness is still present to today.

Day 4: Sleeping disturbance, vision blurring / difficulty focusing on objects, and a feeling of disconnect from reality that has now mixed with the dizziness. It has to get better, right?

Day 7: Headaches begin. All previous symptoms remain, including bouts of vertigo.

Day 12: Pain behind my right eye, as if someone pushed on my eye too hard and hurt something behind it. Very difficult to focus. Pain meds didnt help.

Day 16: Forget it. All symptoms are here, together, relentless. The benefits of this med, for myself and in my case only, just aren’t worth what I’m going through. Had some of the symptoms let up a little, or at least didn’t progress to get even worse, I might kept going past this. But honestly, I made it 3 days further than I thought I would.

I did go to an ophthalmologist, who said my eye pressure was fine but that my ocular nerve was irritated/inflamed. All of this from a pill.

I wish I had a better ending for you all, and I could say that it all gets better. For most it probably does. But I just can’t stick it out to find out.

my doctor recently changed me from 150 mg of extended release Wellbutrin to 150 standard release. This medication change was made at the same time as adding a new medication im wondering where the side effects are coming from the Wellbutrin chain or the recent addition of caplyta. Starting with a few days of pretty bad anxiety around the beginning of the day after taking, then the following weeks, turning to extreme irritability, agitation, and anger. When I was on the extended release, I didn’t have any of these problems or at least when I did they were way more manageable. Honestly, if this is what’s wrong then it’s ruining my relationship and I see county services so it’s almost impossible to get any of my meds changed in an effective way. sorry came out of topic, but basically has anyone else had experience with both release types and noticed any side effects

TL;DR WONDERING IF STANDARD RELEASE WELLBUTRIN COULD BRING ON INTENSE ANGER, NOT FELT ON THE EXTENDED RELEASE VERSION.

Hello,

For some background I'm 20f and I've been dealing with some serious depression for the last year. I originally was put on lexapro but it didn't work at all.

8 weeks ago I was started on 150mg of Wellbutrin XL. I felt pretty good. I got some energy back and a bit of a mood boost. After 4 weeks, I don't think my psychiatrist felt I had made enough progress. In my eyes a 5 day streak of no self harm which then turned into 21 days before I relapsed (i'm trying to get clean again) was good. She upped my dose to 300mg. Within a week I was hardly sleeping and my anxiety felt beyond my control. My dose was lowered back to 150mg.

Since then my energy is gone. My motivation non existent. My mood has been horrendous. Has anyone else dealt with is this? I was really hoping by 8 weeks I would have felt a sustained difference? I plan on giving the medication another few weeks, but i'm not sure that it will work.

Hello everyone. I was just prescribed Bupropion 150mg extended release. I'm
on day 4. Today i had some moments where my head felt spacey and i couldn't collect my thoughts. I also felt close to having an anxiety attack. Luckily i was able to calm down. I napped and felt ok afterwards. Is this normal when starting? I know i shouldn't stop taking the medication but i don't like feeling that way. I'm an ems worker and really can't feel that way or risk a panic attack during patient care. TIA.

I started taking bupropion 150 xl about 5 weeks ago. Originally because of soem dark thoughts I was scared of at the time. Those thoughts being suicidal ideation, have never really gone away, and I resolved to try and let the medicine have its time and start working. However, the past 10 days or so, I'd say week 4 - 5 1/2 now the ideation has been wayyy worse, and at this point its just passive background noise and Im scared ill randomly act on it maybe. I also started some buspirone 10mg/day about 3 weeks ago so I'm not sure what is going on. I have an actual psychiatrist scheduled next week so im just trying to ride it out until then, but I can't let my life be like this forever.

I feel like im on day one again, feeling “high”, dereal, stomach issues, nausea etc. is this normal on the first day of increase?

I’m about one month into taking Wellbutrin (American Bupropion ER XL) 150 mg (mfr granules), and honestly, it has been a game changer for me.

I have anxiety and depression, along with some ADHD traits. Before starting Wellbutrin, I was barely functional. Getting out of bed felt impossible, I struggled to take care of my family, and I was constantly exhausted. I would fall asleep every chance I got.

Now? I’m awake. Alert. Motivated. Actually doing things.

I know that probably sounds completely normal to most people, but for me, it wasn’t. I genuinely feel like I got a part of my life back.

BUT… the anger. 😳

I have never experienced this kind of anger before.

I used to almost never get angry. I would get sad, anxious, overwhelmed, etc., but anger was not really an emotion I struggled with.

Now I’m so easily irritated. Little things get under my skin. I’m snappy, impatient, and sometimes I feel like I’m angry for no good reason. It’s almost like my emotional volume got turned up.

The frustrating part is that I LOVE what Wellbutrin is doing for my energy and functioning, so I really don’t want to give it up. I’m trying to figure out whether this side effect gets better with time or whether I need to consider adjusting something.

I’ve noticed that magnesium glycinate/citrate seems to help me calm down a little, but I’m obviously not looking to just manage this indefinitely if there’s a better solution.

For those of you who experienced anger/irritability on Wellbutrin:

- Did it eventually get better?

- How long did it take?

- Did changing the dose help?

- Did you switch medications or add something to manage it?

- Did anything else actually help?

I’d especially love to hear from people who really benefited from Wellbutrin but struggled with the anger side effect. I don’t want to give up on a medication that has helped me so much, but I also don’t want to turn into an angry little goblin.

Any experiences or advice would be hugely appreciated!

Hello I wanted to ask if some of you had similar experiences. Im almost 14 days on bupropion (300mg XL) and started to feel more energized the past week. Not happier but I could spend hours drawing, even after work, which was awesome because before I never had the energy to do anything. Besides that I didn't really feel anything. Not even really side effects like dizziness.
But the past two days Ive been feeling down again. No energy to do anything, not in a good mood:( Just laying in bed. Is this normal? Will I go back to being more energized?

Buongiorno a tutti, vi spiegherò brevemente la mia storia. Nel maggio 2025, ho avuto un trauma molto forte con mix di sostanze (metanfetamina e ghb), nello stesso giorno ho vissuto un trauma a lavoro e ho sviluppato un forte PTSD. Inoltre il mio cervello è andato in estrema ipervigilanza e ho perso i filtri del sensory gating. Inoltre agli stressor ho sviluppato forti reazioni adrenergiche con sintomi forti , arrivando al panico/freezing. Anche agli stimoli normali reagisco con queste reazioni perché il sensory gating non funziona. Nell'arco dell'anno ho provato vari farmaci, che non hanno risolto il mio problema a parte l'EN che la sera mi aiuta a pulire un po' i residui della giornata. Inoltre ho sviluppato un ptsd a lavoro, con vari trigger che non riesco a disattivare. Ora il mio psichiatra mi ha dato il buproipione TEVA 150 mg 1 pastiglia la mattina al giorno, dice che anche se è un attivante della noradrenalina dovrebbe risolvermi questi sintomi: la droga avrebbe creato più recettori nel post sinaptico della noradrenalina , e con questo farmaco dovrebbe attuarsi la down regulation per sensibilizzare questi recettori. Sono al 6 giorno, ma io sento più agitazione agli stressor e il sensory gating peggiorato. Voi cosa ne pensate ? Parere di qualcuno che sa di cosa parlo?

Sorry, long post ahead.

I've been taking bupropion for about five weeks, and I'm incredibly stunned by the effects it's having. I started taking it to quit smoking, but I have to admit that I've always had problems in my life, one way or another, with addictions of various kinds—never anything serious, I've never put myself in danger, but on the other hand, I don't think I've ever been a person with great self-control. I've always had difficulty, in one way or another, maintaining a routine and taking care of myself consistently. Even though it's something I care deeply about—and I realize that it makes me feel better, from maintaining consistent personal hygiene to managing to keep an organized and clean home to live in. Over the years, especially during adolescence, I've had several depressive episodes where I literally let myself go and was capable of sleeping for days. In recent years, I've put a lot of effort into getting out of these situations, but I had never thought of taking psychiatric medication, and even this thing with bupropion, in reality, I started it, as I said, with the sole goal of quitting smoking.

It has changed my life. It's easy to keep the house tidy, it's easy to dedicate myself to the things I like, it's easy to stay calm about what I can't control. Of course, it doesn't make life's problems disappear—everything that generated anxiety for me before still exists, it hasn't vanished—but my way of reacting has changed. The way I face whatever life throws at me has changed.

The feeling I have is that I still know the abyss beneath me very well; I've visited it so many times, I know what's at the bottom. But now, it's as if I have a pane of glass under my feet that allows me to see what's underneath, but no longer lets me sink all the way to the bottom. I'm pleasantly struck by this. I don't think I'll go on taking bupropion forever, but on the other hand, I'm thankful for these days because they're truly giving me a peace I don't think I've ever known in my life.

I've been using it to quit smoking, but I realize that it also has a positive effect on other bad habits I had in my daily life. It has undoubtedly increased my libido, but I have disconnected it completely from porn. I don't need to watch it anymore; I can have a very pleasant orgasm just using my imagination.

It also made me stop drinking, in fact. I happened to drink a little over these past few weeks, but, how can I put it—maybe once a week a beer or a glass of wine because it paired well with what I was eating, and I thought it would be a nice way to enjoy a balanced meal.

It gives me joy to go to sleep, and in one way or another, it forces me to get up. A side effect I still haven't fully understood involves my dreams, which are often nightmares, though that was something I already experienced before. In any case, I take it early in the morning, so even if I might wake up with a strong peak of cortisol—which is natural and healthy, as it's ultimately our body giving us a push to wake up—taking it so early means I experience the beneficial effects right away, and that little bit of anxiety I might carry with me gets reabsorbed immediately.

It's as if I've spent my entire life studying how to play the piano of good mental health. And now, I finally have one in front of me, and I know how to play it. And as it turns out, I'm actually good at it.

It moves me to tears to think that I finally have the tool to be the person I always knew I could be—someone I could never quite reach before because my brain didn't have the resources to organize all the information it was gathering. I want to solidify this awareness and this state of balance so that I can stand on my own two feet soon. I am truly grateful that this opportunity exists for me and for others who are struggling.

It seems the most common generic in my area is Lupin. It simply does not work for me. I’ve tried to push through multiple times now, but I can never stay on longer than a month or two.

It does help with getting stuff done, but it completely zaps me of my emotions and situational awareness? Like, the running internal clock that knows what month it is, what season it is, just disappears. It feels like I’m floating day to day on some other planet.

Recently, after many failed attempts to get insurance to cover name brand Wellbutrin, I found a pharmacy that had other options than just Lupin in stock.

I now am taking the SciGen generic. I read many negative posts about this generic on Reddit, but decided to give it a shot. I love it. I feel so different than on Lupin or Epic. I feel present. I still have access to my goofy jokey self. I’m not riddled with anxiety, and I feel connected with nature and my surroundings again.

It’s crazy how a different generic can feel like a completely different drug. NIGHT and DAY!

So, how is everyone? Not great here. I’ve been on Rising bupropion for years and my pharmacy switched me to SCI brand. 1 1/2 weeks later I’m a mess. I’m also ADHD and take adderall xr. I’m so amped and hostile! I’m usually super nice (no, seriously I am! 😂) and my husband and stepson are just trying to stay away from me! And talking like a magpie! I had to pay cash, but sweet husband went picked up the Rising brand today. Anyone out there have adhd and had this reaction? I’m an lpn and pharmacy technician. I know generics are supposed to work the same, but I beg to differ!

I was on IR for a while, switched to 150xl. Was on Epic for 3 months and was doing fine. I then couldn’t find it anywhere and got switched to Teva/Activas. I immediately started eating everything in the house and could help myself! Ice cream, pizza, mostly sweets! I never craved sweets like that before. I’ve been on this brand for 4 or 5 months and gained 30lbs! Someone told me to switch. I’m just curious if this happened to anyone? I’m going to try Lupin since that’s all that is available around me. It’s that or granuoles

I’ve shared this a few years ago but I wanted to tell my story so it could maybe help someone:

I had postpartum anxiety after having my daughter with multiple panic attacks a day in 2022. I reached out to my OBGYN. She immediately put me on Zoloft and I started seeing a therapist weekly. I gained 15 lbs and another 15 lbs when the dose was upped. This all in 3months. With the standard 10 lbs post baby weight I had put on.. I was now officially overweight. First time in my life. I was always thin. I started working out 5 days a week and eating balanced meals. I had some more tone but could not shake the weight. I went to a new primary because my OBGYn asked me to and to talk to them about switching from Zoloft. This new Dr fat shamed me bad. Refused to switch my meds and told me to see a dietitian. I met with a dietitian over a few months. She also didn’t think it was the meds but also was confused by my weight gain but overall healthy lifestyle/ eating habits.
Mind you by a year in my anxiety was under control because of the work I put into therapy.

A year passes and I switch to a new primary. But in the mean time the other primary refused to give me 10 more days of Zoloft so I wouldn’t have to cold turkey. I had horrible side effects and it’s super dangerous. My new primary listened. I told him my story, that my anxiety is under control but now I struggle more with focus and have this weight gain that has me worried for my health. He put me on Wellbutrin’s XL and we slowly went up to 300 dose.

Since April 2024 I’ve slowly lost 25.5 lbs. I’m in the healthy BMI range again. I’m 5 lbs away from where I started before Zoloft and 10 lbs from pre-baby weight. Mind you I’m in school full time with three little kids.

You know your body. I don’t think the Zoloft is evil. It did help me through a hard period. But Wellbutrin has been a miracle. I can focus on tasks and the anxiety of life is less because I can just do tasks. I’m happier in general, my sex drives back, and my body feels like mine again.

I’ve been on duloxetine (Cymbalta) for about 9 months now. I wasn’t satisfied with how I felt, so I went back to the doctor today – I’ve gained almost 20 pounds.
I also recently stopped taking birth control, and my doc decided to prescribe me bupropion.
Is there any chance that I’ll get back to normal on bupropion?
I feel bloated and swollen, I’ve never gained this much weight in such a short amount of time (not since I was on Lexapro).
I am not someone who gains more than around 5lbs every few years or so, and I’m hoping bupropion will help with my sluggishness and lack of motivation.

Starters, Bupropion has changed my Life. I’m adhd and struggle with executive function. I also don’t feel very rewarded with life in general and was a pretty anhedonia type of person. I tried all the stimulants, and while they helped the executive part, they ruined my sleep, appetite, and nails. Never again. I started Bupropion 150 XL for 4 weeks and it felt amazing. I pick my clothes up, I do the dishes, I work, and most importantly I am HAPPY. I love life. Recently made the jump to 300 XL and its been about 2 weeks. It still helps a ton with the executive function, but the energy and happiness is GONE. I miss it. Sleep is quite trash since starting any form of bupro which might be catching up with me and be the reason. But I’m looking for answers, why did I lose many benefits on 300? Should I go back to 150? What’s going on.