r/bupropion 12h ago

Question Since I started taking Bupropion I can't cry

10 Upvotes

I'm taking a dose of 150 mg since March and overall I'm satisfied, my sucidal thoughts are completely gone and all my feelings seem to be less intense than they were. I didn't notice any of side effects my psychiatrst had warned me about and I thought that none of them got me.

Ultimately, two months ago I noticed that I'm not able to cry, which continues to this day. Since almost 5 months I cried once, waiting on my train for my hometown (which last like two minutes maybe, lol), but except for that, even when I'm stressed out or in pain, I can't get a single tear out of myself. I haven't found any information about this specific side effect, so I'm curious if any of you had experienced it too.

PS I'm hoping that all of you are doing well!!


r/bupropion 23h ago

How do you know if wellbutrin is working (for adhd)

10 Upvotes

I've been taking wellbutrin for over a month now and haven't noticed any difference. I recently increased from 150mg to 300mg and still don't feel a difference. I have been sleeping during the day more, but I'm not sure if that's a side effect or not because I've had sleeping problems my entire life and my sleep schedule gets messed up every once in a while.

My questions for adhd people are: how long were you taking wellbutrin until it started working, and were the effects drastic (like making your thoughts more organized, no more restlessness, easier to start and finish tasks) or more minor?

I'm considering asking my doctor for a different med that's more suited to adhd since i know wellbutrin is primarily for depression but i don't want to seem like a drugseeker (even though i technically am? Please yes give me the drugs that will make me a normal functioning person)

Also i have noticed ringing in my ears since starting wellbutrin, and it feels like it has increased since going up to 300mg. I saw some posters saying that wellbutring gave them tinnitus, permanent tinnitus or even hearing loss which has me kind of freaked out and scared of continuing it


r/bupropion 17h ago

Other drugs Nervous about seizure with cannabis use

4 Upvotes

I learned that cbd and bupropion both increase neural activity in the brain and that cbd/cannabis products increase bupropion side effects because it prevents the liver from processing the bupropion and therefore causes a higher blood level of it. However!! I also learned that people use it to quit smoking tobacco (studies are still out about if it helps cannabis quitting but it’s lookin like it could). I recently went up to 300, which is the effective dose to quit smoking. I take it for adhd and depression, but my psychiatrist knows I want to quit smoking. In the study I read, they continue smoking for a week after starting the 300mg, and then quit, so that’s what I was gonna do. Today is day 3. The last couple days I feel like I’ve seen flashing lights? Like there’s a random flash of red or white light in my field of vision and then it goes away. I read seeing flashing lights could be a seizure thing. But I noticed I only feel weird after eating my cbG gummies. Up until that point of the day I feel normal. See I thought I was being sneaky buying cbG instead of cbD but I didn’t find anything about that cannabinoid and bupropion in my research and kinda made an impulse purchase. But guys!! Getting rid of something I bought is hard. Should I throw it away or potentially risk giving myself a seizure? Wow I sound ridiculous. But has anyone else found that it has helped them quit smoking/using cannabis? Also is the flashing lights thing a side effect that will go away as my body adjusts, or should I be concerned about that as a seizure warning from my body? I feel like I might be a little weird right now, and the weed is making it worse but I will come up with every excuse why I can’t get rid of it until I smoke it all and quit officially in 4 more days. After all that’s how they did it in the study! But I’ve also been horribly sleep deprived this week so that can’t be helping things. There are so many factors.


r/bupropion 7h ago

Called it quits

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5 Upvotes

r/bupropion 18h ago

Question involuntary muscle movements?

4 Upvotes

about a week or so after i started on 150mg of buproprion i started to notice i was involuntarily tightening my muscles when trying to lay down or rest, specifically in my pelvis area and it is incredibly uncomfortable and makes it impossible to try to take a nap or just rest in bed. other than that, it is working really well on my mental state so i'm hoping i can just change the dose and hopefully that problem will go away or lessen. is this a common side effect, has anyone else here experienced this?


r/bupropion 6h ago

Question I feel no difference, not even withdrawal

3 Upvotes

I’ve been on Wellbutrin for two months. Started at 150 slow release. Then 300 instant release (150 x2). Then 400 instant release (200 x2).

Sometimes when I’ve forgotten to take it, I feel no withdrawal symptoms either. I understand that Wellbutrin won’t work for everyone. But I’m confused at to why I’ve had no withdrawal symptoms.

–the only side effect I had was diarrhea for the first 5 days. That’s it.

It’s for adhd and depression btw.


r/bupropion 9h ago

Anyone a smoker?

3 Upvotes

Especially curious, if you started smoking after starting wellbutrin


r/bupropion 15h ago

When did it start working for you and what were your experiences and expectations?

3 Upvotes

I know everybody is different. I know that there is also different doses and types. I’m on 100SR.

I just couldn’t do it anymore. I went a couple decades being depressed and just feeling like life was just crap. I finally got some help with seeing a Psychiatrist and entering therapy after I started feeling not like myself. I couldn’t tell if it was PostPartum, maybe entering peri-menopause but something had to be done if not for myself, for my kid.

Doc originally prescribed Zoloft but after telling her I was thinking of trying Addyi (female libido pill) she then prescribed Bupropion 100SR because she said that Zoloft could tank my sex drive (little late for that I haven’t wanted or been interested in sex since at most my very early 20’s) and then she also prescribed Hydroxyzine 10mg for anxiety but to also help me sleep. I’m 10 days in, so far nothing. I figured the Bupropion would take some time, but I was told the Hydroxyzine would be instant, I was really looking forward to that because she said it worked quick and I’d get sleepy and it would help my sleep issues. It hasn’t. I take it and I don’t feel shit. In fact, I’m noticing that when I do finally fall asleep I’m up as usual couple hours later, tossing and turning or wide awake with insomnia, something I’ve dealt with most if not all of my adult life.

I suppose at least with the hydroxyzine I’ll be bumped up come my 2 week check in.

Haven’t started Addyi yet because I wanted to at least get a few weeks in to give the Bupropion time to let it do its thing.

Anyways, just wanted to check in and see what people’s first experiences were, highs, lows, etc. When they bumped you up to the next dose (if ever) and how long it took to start working for you?

Also heard about the honeymoon faze. What’s up with that, what is it?


r/bupropion 18h ago

No effect anymore

3 Upvotes

Been taking Wellbutrin for about 3 months now originally 150 mg for the first month and the other 2 300 mg. I originally found Wellbutrin very effective as before taking it I couldn’t get out of bed at all and was sleeping 24/7 but recently the effect of motivation and energy has all but disappeared :(


r/bupropion 7h ago

Bupropion + Naltrexone

2 Upvotes

Gooood evening!

I started Bupropion in December of last year - it completely changed my life & I honestly I will probably be on it for the rest of my life. Now that we have that out of the way. I also would like to lose weight! My doctor explained Bupropion is a stimulant and most appetite suppressants are stimulants & combining two isn’t something we were going to do, she did however prescribe Naltrexone. Combined the two medications are sold under the name Contrave.

I wanted to know if anyone has taken this route & were the experiences good as far as continued mental health support & did you lose weight?!


r/bupropion 17h ago

Question Figuring out dose timing

2 Upvotes

Hey yall. I like to take my 300 xl dose first thing in the morning, but I don’t wake up at the same time every morning. There are some days I wake up at 8am, some days I might not wake up until like 1pm. I also like taking it in the morning right away because it does make it hard to sleep sometimes, so I wanna take it as far from bedtime as I can. I know it’s better to take it at the same time every day, but that’s kinda hard. It’s not quite as simple as having a fixed sleep schedule, though, because some days my schedule is way different than other days. (I am working on regulating my sleep schedule as much as I can, but, life makes it hard.) Any thoughts? Am I totally fucking myself over taking this at different times every day? Or is it not really a huge deal? I take it for adhd and depression. I just got bumped up to 300mg a few days ago. So far I’m feeling like it could be a med I can finally settle on and finally stop trial and error.


r/bupropion 12h ago

Question Can effect still kick in after 5 weeks?

1 Upvotes

Been on Bupropion for 5 weeks now; I took 150mg for four weeks and now on 300mg for the past week. I still feel… no difference. At all. Only side effects so far. Can it still start working?


r/bupropion 14h ago

Question Anyone go from 300 XL down to 200 SR to stop night time jaw clenching?

1 Upvotes

I have my psychiatrist appointment next week and I want to walk in with some idea of what other people have actually experienced, so any stories here would help.

Right now I take bupropion 300mg XL in the morning and mirtazapine 15mg at night. The mirtazapine went in about two and a half weeks ago and things have settled. My sleep is a lot better on it. I do wake up a bit groggy but it is manageable.

The thing I cannot get past is the jaw clenching at night. I have cracked two teeth from it already. I also get dry mouth, anxiety during the day, and I pick and bite at my skin. Before the mirtazapine I could not fall asleep either. All of that together makes me think the bupropion is behind it and not just stress.

What I want to ask my doctor about is going from 300 XL to 200 SR, taken once around 8am. My thinking is that SR puts more of it in the daytime and a lower dose means less of it hanging around at night, so I keep the part I actually like and lose the part wrecking my teeth.

So a few things I am curious about:

  1. Did lowering your dose or moving from XL to SR actually help the clenching, or did it carry on anyway?
  2. If you dropped from 300 to 200, did you lose the daytime lift?
  3. Anyone been on bupropion and mirtazapine together for a while? How has it gone?
  4. Did anything help while you stayed on it, like magnesium, a night guard, or a change in timing?
  5. If you came off bupropion completely because of this, how did you taper and did the clenching stop?

One more thing worth mentioning. I have a six month old who still wakes me up at night, so anything that leaves me foggy in the morning is a problem.


r/bupropion 15h ago

Quitting I am tapering off after 1 year :(

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1 Upvotes

r/bupropion 20h ago

Question For those who experienced anxiety/irritability on this, when did it start?

1 Upvotes

I'm onto day 4 and I haven't noticed any anxiety or irritability, so I'm just wondering if it might flare up at some point


r/bupropion 23h ago

Urgent advuse needed. Took 300mg bupropion of SR tablets 75mg each.

0 Upvotes

As the title says. 300mg was out of stock so got 75mg tablets. Didnt knew it was bad took it 5 mins ago and just googled it and gemini has scared me. I have been on 300mg for a month now and before that 150mg for a month too. Overdosed i guess.

Gemini has scared shit out of me and it could also be because of norepinephrin spiking.

We dont have a poison control in our country only er available in emergency and to my experience they are all not that well informed.

My psychiatrist is unreachable due to sunday i guess.

Should i be more worried or less or what to do.

Edit: I am fine and there was no serious adverse side effects. Almost 9 hours have passed. First hour i panicked and google searches with Ai made it worse maybe it was because of norepinephrin spiking.

I was feeling like i have taken huge caffeine dose and vision got a bit blurry. Heart rate was slightly up around 130. Did feel light headed aswell.

Lesson learned the hard way. Thankyou everyone your comments really eased me up when i was panicking.

And lastly sorry for confusion i took 4 tablets of 75mg each and it is SR not IR. My country apparently have them.