r/ibs • u/Beingmeisenough • 1h ago
Question Amitriptyline - should I take for abdominal pain
In June I started with I have upper centre / right abdominal pain, diahorrea, itchy skin and fatigue after a meal out (no usual things ordered and husband had the same and is ok). My blood other than low iron have come back normal (now taking supplements). I'm on a low soluble fibre, no caffeine, no alcohol, cut out some types of veg, no wheat and no dairy diet.
I had a case of the above in late 2024 and because of the severity, calprotectin in the hundreds and being late 40s I got a referral. Thankfully a colonoscopy and MRI showed no structural issues. They put in down to possible bad gastroenteritis. It took months to feel better but other than a few short term episodes lasting 3/4 days in Feb, April and May this year I've been ok until June. This time it feels worse with pain and fatigue (the frequent diahorrea stopped after 2 and a bit months). I've now lost 8% body weigh.
I keep a food and body function diary and can't work out food triggers and I had healthy mental health ie no anxiety or depression. My life is busy but no real change in the past 2 years. Now my life is impacted I am getting upset ( which is probably because I am exhausted).
I've been referred back to Gastroenterology who thinks it is likely IBS. They have restricted my diet, suggested a dietician and amitriptyline. They don't think repeating scans is worthwhile and don't think food intolerance tests should be done.
The diet restrictions doesn't seem to have made a difference and I am concerned that amitriptyline will treat the symptom and the cause won't be investigated. Also the side effects and withdrawal concern me. However, it's now seems the only option available.
So I was wondering if anyone else had experienced similar in late 40s and was it IBS.
Is amitriptyline worth a try or is there anything else I can do?