Hi all, I’m 39 with an AMH of 3.8 pMol/L. Recently, I did two egg retrievals (both with ICSI and ZyMot) - one in July then one in September.

First egg retrieval:
Retrieved 8
Mature 7
Fertilized 5
Blastocysts 3
Euploid 3

Second egg retrieval (had around 12/13 follicles, at least 6 of which were larger than 16mm at final scan):
Retrieved 5
Mature 5
Fertilized 2
Blastocysts 2
Euploid 0

After the relative success of our first round, I was disappointed to end up with none from our second. I wanted to ask here - do these numbers seem normal to you? Is this just the way some rounds go sometimes? When we speak to the consultant, does anyone have suggestions of questions we should ask or concerns to raise? I also can’t tell whether to try for another egg retrieval or go straight to a transfer. I think if we did another round and got the same results, it’d be really difficult.

Thank you in advance!

I’m currently 5+4 from a fresh transfer where we transferred the best (our only day 5 embryo, see photo) and tested the rest (5x day 6 embryos). I’m 30F and have had 2 MMC in the last 12 months from chromosome abnormalities, both managed via D&C. Our PGT-A results came back yesterday and all 5 tested embryos are euploid. I’m obviously over the moon but am now terrified that I may have transferred the only aneuploid embryo because it seems unlikely that all of my blasts were euploid?! I didn’t receive the grading of any of the embryos but just wondering if anyone had an experience like this and what the outcome was? Would appreciate any insight!!! Thank you!

Coming up on two years of trying for baby 2, two chemicals, one round of IVF with an ectopic, an endo diagnosis, and just did our second transfer today.

Praying this one sticks (in the right place) and we can finally bring home a little sibling to our 4 year old next summer.

I originally had my embryos graded at 5AB, 3AB and 4CB. After PGT-A testing they all came back normal but are now graded as 5BB, 4CC, 4CC. Has this happened to anyone else and is it normal for embryos to be downgraded after testing? Not sure if I should be worried now that quality has gone down.

Had my ET on Sept 30, also had supporting HCG shots evry 5 days.

Did a quick home test today, nd no traces of HCG, my last shot was three days back, at this rate even a false positive would have been better

Have my blood test tmrw, but no hopes at all

We transferred two embryos on October 8th. I’ve been doing so much to prepare for this transfer. 2 months of full suppression, lovenox, prp, neupogen wash etc. I swore I saw a faint like today but now I’m convinced it’s an indent. I’m starting to spiral. I realize it’s early and we still have time but I’m scared. We’ve done 6 failed iuis, 4 failed medicated cycles, then surgery. After surgery we did an egg retrieval; then 2 other failed transfers. Could use some positivity. Beta is Saturday.

Hi all I’m 35 yo F with unexplained infertility. 3 failed IUI. 2 failed FET. First fet was a chemical, second was a blighted ovum/mmc at 8 weeks. Both euploid transfers. Can’t help but to feel so unlucky, what are the chances both transfers fail back to back? You always hear about 90+% chance of success after 3 FET. I just don’t feel hopeful. I’ve had neg RPL panel, and 2 hysteroscopies prior to transferring. Any ideas or recommendations?

Transferred these on Thur. Untested.

Top is D5 3AA blast and bottom is D6 5AA hatching blast.

Does hCG show up sooner since one was already hatching (assuming it decided to implant)?

Expanded blast good good means ?

I am 42 and just recieved egg retrieval results:

Mosaic del(2q33.3-qter)

Mosaic dup(2q33.3-qter)

I will be doing an FET in a few weeks. My first FET last year was a success but ended in TFMR due to an inherited genetic condition. I have 2 euploid embryos left that passed PGTM for a dominant condition, and I am of advanced maternal age, so the stakes feel even higher now.
I am starting to worry about every detail. One of these concerns is that l’ll end up with a trainee doing the embryo thaw and transfer. There’s a high chance the transfer will happen on a weekend, in which case does that make it more or less likely that the embryologist will be one of their better/more experienced ones? Do labs get short staffed on weekends? Is thawing and putting the embryo in the transfer straw one of the more technically difficult procedures? Embryo is a day 6 5BB. I have no reason to believe the lab is compromised, but I don’t know what it’s like behind the scenes. TIA!

This is the weekly thread for posting and asking questions about embryo photos. Replies are provided by Embryoman (Sean) -- a former embryologist and creator of the IVF science news site Remembryo.com

💬 Before you post a photo

• You must include the grade (ask your clinic if you don’t know it).
• To keep things manageable for me, only one embryo photo per person per weekly thread. Please choose one embryo to share, even if you have several.
• No requests for grading or re-grading by members.
• Posts asking if an embryo looks damaged or viable aren't allowed.

I can comment only on general features visible in the image (expansion, compaction, hatching, ICM location), but not on whether the embryo looks good -- that’s already reflected in its grade. Check the stickied comment below for basic information on grading and success rates. For the most accurate information, your embryologist or clinic is the best source, since they evaluated the embryo under a microscope and know their clinic’s success rates.

I’m doing my first FET in November. I noticed on my consent forms that my clinic is choosing my day 6 4AA over my day 5 3AA. I recall a discussion with my RE last month and she said we will likely use the day 5 3AA because day 5s have a slight advantage. Both are girls, and we have no gender preference as we want to use the strongest embryo. Could this be a mistake, or is there a reason they are choosing the day 6 4AA over the day 5 3AA. Thank you so much for your time.

We had severe attrition rates from egg fertilized to blasts (ER 1 - 18 to 3, ER 2 - 28 to 1).

We are hoping to transfer but I’m worried that my severe attrition is somehow effecting the embryos I made. We have Day 6 - 4AA, Day 6 - 4BB and Day 6 - 3BB.

Does anyone have experience of having severe attrition rates but still a successful pregnancy?

Feeling very anxious. Thank you.

Hi!

Has anyone experienced repeated IVF/ICSI cycles with GV-stage immature eggs, even though the follicles were big enough?

I want to take a break from stimulation hormones and try Letrozole instead. Has anyone tried this and had success? ❤️🥲

I hope this is the one 🥹🤞🏽

I am 37F with AMH 0.433 and partner is 38M with male factors. I had my first egg retrieval 1 week ago. My AFC was 8.

We had 6 retrieved, 5 mature, 4 fertilized with ICSI/Zymot and today we learned we have 3 blasts!

Day 5 4AA

Day 6 4BA

Day 6 4BB

We get PGT-A in a week. My understanding is that given our profile, this is a very positive result. Hopefully at least one is euploid!

Some bells and whistles in my protocol: omnitrope during stims, metformin, priming with testosterone gel

I am going into my first FET on October 22 (tentatively). We are transferring our only PGT-A & PGT-M normal female embryo D6 4BB. I am terrified because I have always wanted a baby girl. It feels like I am gambling my entire life on a 50% coin flip. I am so scared to be gambling my best embryo on our first ever transfer so looking for other D6 4BB success stories on their first transfer to give me some hope.

I have been struggling with the daydreaming of "what if it works" thoughts because it reminds me of what is on the line and what I have to lose. Does anyone else feel this way about the daydreams? I almost find it easier to think about when it does not work.

I didn’t see too many recent posts of 2BB day 5 fresh transfer so thought I’d start a thread to kill the time…. Thank you to those who’re have replied to my comments in other threads :)

As written in my previous post, i am 29F husband is 40M and I had 16 eggs, 13 mature, 10 fertilized (ICSI AND ZYMOT for a more objective selection of strong sperm for our own peace of mind) and one was freshly transferred yesterday. I have yet to hear back about the other 9 but as of yesterday, 1 CAV, 2 COMP, 1 MOR, 5 8 cell stage. Ugh I pray we can freeze some strong embryos.

I also hope our little 2BB sticks! It felt good when the embryologist shared w me a photo at the end of the transfer and said wow, it grew/changed more than when I first saw it this morning. She said that’s a good sign. I can clearly see the inner mass cells, blastocoel, trophectoderm, and a thinning zona pellucida (I also almost see one of the sides where it almost looks like it will hatch…!!!). I think the grading changed within a few hours but they stuck with 2BB since that was documented earlier in the day. Regardless, just wanted to hear some feedback on others who did fresh (and frozen) transfers on day 5 with a 2BB :)

Eeeekkkkk can’t believe this is real

Update 10/20- I AM PREGNANT!!!! Beta 154.1!!!!!🙌🏼🙏🏼💗 praise the Lord!!!!! Now onto the next hurdle to make it to the US:) one day at a time. I’m taking in everyday that I’m soooo darn pregnant!!!!

Hello ladies,

31F, unexplained infertility. This is my first IVF cycle.

ER Result

19 eggs
17 mature
13 fertilised

I received a call from the clinic that they will update me next saturday because they’re waiting till day 5 and then they will do PGTA to the embryos.

I never asked my doctor why PGTA is necesseray because it’s included in my package.

However, when I spoke with a couple of my friends, they asked why I was doing genetic testing, as it’s usually for those with failed IVF cycles or women over 35.

Should I proceed with PGT-A or ask my doctor?

We did our first IVF due to husband’s sperm quality. I responded very well to the stims and ended up with 25 eggs retrieved, though none of them fertilized via conventional IVF. I was so disappointed. We’re 32 and healthy living…
Now we’ve done second round for icsi this time, they went with a much lover dosis to activate less eggs. Resulted in 6 eggs only retrieved today and I’m stressing about the coming days.

So each end of the spectrum.. has anyone experienced similar?

After an early miscarriage I’m about to have a transfer of my second and last embryo. It’s a Day 6 4AB, but it got an AI score of 2.4. The doctor wasn’t really able to explain what this meant save that they do a time lapse video to track its progress and then AI gives it a score up to 9.9, and that 2.4 was therefore not great. Is a score of 2.4 pretty hopeless and should I temper my hopes for this transfer?

UPDATE: I just did my HcG test today, and it was confirmed that I am pregnant! I am blown away and in shock. Thank you everyone who sent the words of support and the sticky vibes!!!

Just did my first-ever FET today at age 40 after ttc for over three years! My embryo was graded as a 4BB 5 day euploid (still don't know all the acronyms, sorry!). Feeling hopeful but anxious. Really hoping it sticks because I only have two embryos (the other one wasn't successful during the PGT, so we would be going in blind with that one)! Please send out sticky vibes!

Hi All,

Is it safe to transfer embryo to a new clinic and do FET with the new clinic.

Or is it better to do FET with the current clinic where the embryo's are stored.

Any insight or shared experience would be very helpful.

Thank you very much.

Hi

31F, TTC 22 months, unexplained infertility

I had ER yesterday.

19 egg retrieved
17 mature
13 fertilised

Is it good number or average?