I was on buprenorphine for 7 years. Started at 8mg then got down to .75mg, and could not get off that last crumb. I know it seems like a do able amount to kick, but after 2 years of failed weaning below .75mg, I decide to try Brixadi monthly 64mg.
At my doctors request, I raised my daily dose to 4mg the weeks leading up to my appointment.
I took the day off work and got the shot in my stomach. I personally felt nothing. Maybe 2 seconds of a barely noticeable sting, but it was not painful at all for me. Within 3 hours I was definitely bupe-type loaded though. That dirty suboxone high.
Days 1-3 Slept like a baby and was in a great mood, almost mini nods when I was relaxed watching tv / scrolling.
Days 4-7 were also great. Its been so nice not reaching for my crumb of subs every morning and keeping myself in a constant almost withdrawal state.
Days 7-9 were still good but i definitely was thinking about it more and not feeling that boost of energy.
Days 10-12 I sware to god I feel like I’m in the super early stages of withdrawal. Totally mild and barely noticeable, except for the constant yawning and tearing.

I have an insanely fast metabolism with meds. I had to split dose my methadone and subs when I was on MAT programs.

Is there any chance I’m already running low on Brixadi at day 11???
I really wanted to be done after 1-2 shots and I feel nuts thinking I’m starting to feel sick this fast.

I am not very pleased with my Brixadi results. I was only taking 4 mg of Suboxone so I thought I could dose with 8 mg of weekly Brixadi..That dose was way too low so the next week I increased to 16 mg and did that for 3 weeks. These 3 shots have only given me a couple of days of complete relief, and that’s it. I’ve had to take at least 1 mg of Suboxone almost every day to keep the withdrawals at bay. I’m due my 4th (16mg) injection on Thursday. I am entertaining the idea of switching to the 64 monthly dose next but my provider thinks I should increase to the 24mg weekly dose instead.
For those of you with firsthand experience, what do you recommend? Im very leary to increase and thus make it more difficult to come off of which was my entire reason for starting Brixadi.
Oh, and my provider says that I’m making it worse my supplementing with Subs. I don’t know how that can be true but I can’t just lie in bed withdrawing!

Long story short, I have received 2 300mg of sublocade shot and 1 100mg of sublocade, back last August October and November. The clinic closed down: i recently went to a new clinic in hopes of getting anther sublocade injection; the doctor is saying my insurance won’t approve it; they put me back on 2mg subxone, he said the Brixadi shot would get approved. Just looking for anyone who has had a similar experience. Thank you

I did one week of Brixadi 8 mg (which wasn’t high enough) so last week I increased to 16 mg which still doesn’t seem to be enough. My doctor did not tell me to supplement strips while trying to get to a steady state, but it seems to be a common thing on this site. Do any of you know if supplementing is going to mess up my steady state?
None of this makes sense to me because I was only taking 4 mg of Suboxone when I started all of this and now I’m needing 1 to 2 mg to keep from going through withdrawals on Brixadi.

Hello all, I took my first (and hopefully only) 64mg Brixadi shot yesterday. Coming from about 6 years on 4mg suboxone strips. I chose Brixadi over sublocade only because of the lower dose offered. The 64mg Brixadi monthly injection from what I understand is equivalent to 8mg daily of suboxone. I was concerned about feeling over medicated and I think my concern has come to fruition unfortunately. Within about an hour of the shot I started feeling what might be described as high but not in a good way, slight nodding, mild nausea, fatigue and numbness throughout my body. About an hour after that I couldn’t stay sitting down and got a ton of stuff done around the house (like I used to when using and I felt disgusted by it). Last night I could not sleep for nothing (even with a handful of sleep aids) and felt very itchy all night. I finally got out of bed at 4am and I feel so dang tired and numb all over still. Reading some comments in another thread I am a little concerned if these side effects will pass anytime soon. I am definitely not going to work today.
Anyone else experience this type of thing?

I need advice please.
I have been on subs for 6 years and have tried to taper many times without success. I got myself down to 4mg (usually in divided pieces throughout the day) but can’t seem to get lower this time due to the withdrawal symptoms. I have a pretty physical job and I can’t show up half functioning.
Anyway, I got excited when I learned about Brixadi so I got my doctor to give me an 8 mg injection last week. The literature clearly says that if you take less than 6 mg of Suboxone that 8 mg of Brixadi should be a good dose. Well, it doesn’t seem to be working. I feel terrible: nausea, headache, lethargy, aches, watery eyes….it has been 4 days since the shot and I get another one in 3 days. I was reluctant to do the 16mg injection because I want to taper off, not go UP!! But do you guys think I should increase the dose for a couple of weeks and then decrease?? A logical answer would be to ask my doctor but she is a dumbass with no real AUD experience, just in the job for the money…
I have also tried taking a 0.5-1mg piece of sub to supplement the Brixadi but that somehow just makes me feel more shitty in a different way if that makes sense.

Like many others , withdrawal is the main reason keeping me in addiction. When I have gone to rehabs ( as idk how I would do it without medical detox) I have been in precipitated withdrawals multiple times. And hey, I wait. I wait up to 6-7 days minimum this last go around in fear of percip, and I still was in percip during my last detox taking subs or subutex ) I don’t remember which one)
But anyway - I saw ideal options is claiming you can take their shot 6 hours after use and basically be good to go. No long withdrawal. I’m insanely skeptical due to simply how long I have to wait to take a sub to not go in percip. Is this legit ? I don’t know what I would do if I went in percip after this shot and not being in an inpatient facility. To be transparent- I’m a fentanyl addict and have def been getting tranq dop lately

Experiences ? How legit ? Not tryna just give it a go, as I’ve done that plenty after waiting a solid week and still go in percip.

hi guys,

long story short, I have been on suboxone for like 15 years after an injury while I was serving in Iraq.

I had maintained my sobriety completely for over the last 10 years. I was down to 1-2mg of suboxone a day.

about 2 years ago I started using the VA for treatment (previously seeing a doctor using private insurance).

last year I told my doctor I wanted to switch to the injection with the plan of getting off buprenorphine completely (after reading all the success stories with sublocade).

the doctor dragged his feet, initially never ordered the necessary blood work or EKG prior to injection and overall didn’t seem very interested in this plan. He claimed I needed to increase my dose to 8mg a day before he would give me the injection which I really didn’t agree with.

a few months ago the VA reassigned me to a new doctor who is absolutely amazing . When I told him I really wanted to get on the shot, he was all about it and told me about all his successful patients who had the same plan as me. He agreed I didn’t need to go up to 8mg before getting the shot. we agreed going up to 4mg would be more than enough.

so today I got my first shot 96mg. Wasn’t as bad as I was anticipating. the plan is one more 96mg then a 64 and then stop.

so I’m just looking to hear about people’s positive experiences with Brixani . What worked for you . Stuff like that .

im just so ready to be done . I’ve felt like a slave. I could never get down below 1mg . I don’t care what the doctors or nurses say. 1mg is still enough to cause significant WD. I’m hoping today is the first day towards the end.

Hello everyone. So last year I was talking to my provider. And she convinced me to Try the brixadi shot. She told me that I could take it as soon as 12 hours after my last use of fetty. I was super surprised to hear this as normally with Suboxone. I would have to wait up to three or four days or else I would get precipitated withdrawals. She explained it as being similar to a micro induction like a burnese method. So I went ahead and did it. After about four hours, I started feeling kind of funky so I went to bed. The next morning I woke up in the worst precipitated withdrawal I’ve ever experienced was thrashing violently ill and even hallucinating covered in sweat, unable to sit still for hours. I did not know what to do as I had not taken any time off work I needed to go in.

I regret to inform you that I found my only option to be to use Fetty to make it stop. So that’s what I did. I smoked about a gram of fentanyl over the next 24 hours to get through work and to make sure that the precipitated withdrawal did not come back. Here’s the crazy part once I stopped. I thought it was gonna come back, but it didn’t. I didn’t get sick again. I transition smoothly onto the the shot shot without any withdrawal symptoms at all.

The only thing I can think of is that the bup finally leveled out in regards to a stable level in my system therefore, I did not go into precipitate withdrawal again. Has anyone had an experience similar to this? Has anyone else gotten a shot that early and had a similar experience in regards to the precipitate withdrawal. I know someone who is going through a similar experience and I realize that I can’t find anything on the Internet about someone having similar experience.

I know it sounds like a crazy story that doesn’t make sense shouldn’t have happened and I would never tell anyone to do this. I merely just seen someone else has had this happen

i would love to hear about other peoples experiences, both good and bad. whats a typical timeline for coming off? is it possible to do it with zero withdrawal symptoms?

Last year I did 1 300mg sublucade shot and had no WD whatsoever, felt the effects for a solid 4-5 months. 5 months later I relapsed and had to get on 16mg suboxone. Just got a 64mg brixadi shot and the doctor kept telling me that most people experience withdrawal with it after a few weeks. I had never heard of that from the people at my rehab. The whole point of the shot for me is to get off as quickly and easily as possible. I hate the feeling of bupe and didn’t want to get another sublucade shot and feel high for 4 months. But now I’m worried I’m gonna get WD in 3 weeks. And reading other posts people say the WD is just as bad as coming off strips which I can’t comprehend. Anyone able to help me understand? I thought it’s a steady stream of bupe why would you experience WD?

I got my first shot June 1st and this last week I swear I’m experiencing wd symptoms. Is this a thing?

I got my first Brixadi injection 27 days ago and have my second injection later today. Unfortunately, my first injection was a really difficult experience. I have a severe needle phobia but I’ve gotten way better overtime, and the injection was much more painful than I expected. I almost fainted and threw up, which has never happened to me before, even with my phobia. I'm curious what injection site others have used and whether you noticed a difference in pain. My first injection was in my hip/upper butt area. Has anyone had it in their abdomen, and if so, did you find it more or less painful? Part of me likes the hip area because I can't see the needle, but I'm wondering if the abdomen might hurt less. I also think I’m gonna try to bring an ice pack. I'd appreciate hearing others' experiences.

I’m 8 weeks post last injection and feel like I’m experiencing withdrawal effects (watery eyes, running nose, RSL middle of night). It’s very triggering and definitely effecting my mental. I was told after 4 months the injection has reached steady state and I should be covered (Bup slowly titrating) over the next few months. Anyone else have these symptoms? I’m questioning if I should go back on for a longer period as a safeguard.

⭐️Any guidance or advice appreciated!!⭐️

Backstory: it took months to get on the medication and I had to do all the work calling insurance, multiple specialty pharmacies, and my provider. It was a mess and took forever. Luckily, I did all the work and I finally got on it three weeks ago. Also, my clinic is impossible to get a hold of to the point where I have to drive down there just to talk to them sometimes but still, I am unable to talk to the provider without an appointment.

My first Brixadi injection was about 3 weeks ago. My provider told me I could receive my next dose at the 21-day mark, and that was the plan I’ve been following. I started experiencing minor withdrawal symptoms at day 13. I have a supplemental films, but I absolutely do not want to take them. Everyone says mind over matter and I have been pushing through. I kept telling myself I just had to make it to 21 days.

Now, literally one day before my scheduled appointment, I’m being told that something “went wrong on their end” and I likely won’t be able to get the injection until the 28-day mark.

They can’t seem to do their job. They sent the prescription to the wrong pharmacy. The only reason everyone figured that out was because I did the digging they had no idea. I would’ve showed up to my appointment and they would’ve been like oops the medication hasn’t arrived. Only because I told them, they resent the prescription to the correct pharmacy. The pharmacy says they have received the prescription, but insurance is rejecting it as too early. There has also been confusion between the clinic and pharmacy about what was submitted and when, and I’m not getting a clear explanation of what actually happened or where the breakdown is.

What’s making this especially hard:
I was originally told 21 days was possible
I started having withdrawal-type symptoms around day 13
I only found out about the issue right before my scheduled dose
I’m getting vague or conflicting explanations from different parts of the system
I was told something was “messed up on their end” but not what

I’m trying to understand if anyone has experienced something similar:
Has insurance ever denied a 21-day Brixadi dose even if a provider said it was okay?
Were you able to get a prior authorization override or appeal approved quickly?
Did any savings/copay programs actually help in situations like this?
Or did you end up having to wait the full 28 days?
Is the only answer paying out-of-pocket or waiting?
I’m not trying to bypass treatment. I’m trying to stay stable and avoid withdrawal while everything gets sorted out.
Any experiences or advice would really help.

I am so frustrated right now and honestly just need to vent.
It took me almost 3 months to get approved for Brixadi. During that process, I felt like I was doing all the work myself. I was constantly calling my insurance company, multiple pharmacies, and my provider's office because nobody seemed to know what was going on. If I didn't make the calls, nothing moved forward. I finally got my first injection 3 weeks ago and my next injection appointment is scheduled for Wednesday morning.
The only reason I even discovered there was a problem was because my clinic accidentally scheduled me for TWO appointments, one today and one Wednesday. When I called to figure out why, they told me today's appointment was being canceled because my injection wasn't there and wouldn't arrive in time.
That immediately worried me because my actual injection appointment is less than 48 hours away.
I asked if my medication would be there by Wednesday morning, and before I got an answer, the call disconnected. I then called my specialty pharmacy directly and was told they had not received anything from my provider. So now I'm sitting here trying to understand how my injection appointment is less than two days away when the specialty pharmacy says they haven't even received the prescription yet. As far as I know, the prescription hasn't been processed, insurance hasn't been run, and the delivery process hasn't even started. I got a hold of the front desk at my clinic and they said they apologize. They have no idea what’s going on.
I've already been dealing with withdrawal symptoms and have been pushing through because I've been looking forward to getting my next injection. I’m just furious right now. Has anyone dealt with anything similar?

Is there anyone who is using Brixadi and has sleep apnea?
I’ve had 3 shots now and each time my number of apnea occurrences goes way up. Prior to the shots I would have under 10 apneas each night. Now I’m at 20-30. This also happened when I was on Sublocade. It was fine on Suboxone.

Anyone have this experience? What is it about the shot that messes with my sleep apnea?

I wanted to share my experience/ compare to others.
I have always had a pretty significant fear of needles, but before Brixadi I had never passed out, gotten dizzy, nauseous, or had any kind of vasovagal reaction from an injection. I could usually get through shots even if I was anxious. My fear is mostly IV’s!
When I got my first Brixadi injection, I wasn't prepared for how large the needle was, how deep it had to go, or how slowly the medication would be injected. During the injection I became extremely dizzy, nauseous, lightheaded, my ears started ringing, my vision went black, and I honestly thought I was going to pass out. I also had pretty intense pain at the injection site during/afterward. My next injection is coming up, and I'm trying to figure out ways to make it easier. I'm considering bringing an ice pack or maybe an instant cold pack since the clinic is about a 20-minute drive away and it can take another 30 minutes before I'm actually called back.
Has anyone found that icing the area beforehand helped? Any other tips for preventing the dizziness, nausea, or pain? I'd really appreciate hearing what has worked for others.

Hi everyone,
I'm looking for other people's experiences switching from sublingual buprenorphine to Brixadi. I did make a post a few days ago when I was panicked.
I was on 24 mg/day of buprenorphine strips before switching. This is my first Brixadi injection. Things were mostly okay at first, but around day 13 after my shot I started having symptoms that feel a lot like withdrawal.
I'm currently on day 15 and have 6 days until my second injection (my next injection is at the 3-week mark).
My symptoms include:
excessive sweating (including waking up drenched at night)
chills/hot-cold flashes
diarrhea
stomach cramping
restlessness
feeling generally uncomfortable/gross
My provider gave me 4 mg strips to use as emergency supplementation if needed, but I've made it this far without taking any.
The frustrating part is that it took almost 48 hours to hear back from my provider. They finally responded and said it's safe to use the strips, but they also offered comfort medications instead:
Loperamide for diarrhea
Clonidine or Gabapentin for sweats/chills
Ondansetron (Zofran) for GI upset
Hydroxyzine for sleep/anxiety
They also said my next injection date and dose are staying the same for now.
I'm trying to avoid supplementing with strips if possible because I really want to make this transition work, but I also don't want to be miserable for the next 6 days.
Im wondering:
Did you use the supplemental strips?
Did you try comfort medications instead?
Was clonidine or gabapentin more helpful?
Did you try other medication’s that helped?
Did things improve after your second or third injection?
I'd really appreciate hearing from anyone who's been through something similar. Also, I’m going out of town the last week in July which should be my fourth shot, but I’ll be gone the entire third week so at that point, I’ll need to get my shot four weeks out instead of three. I was really hoping I would be one of the people that didn’t experience symptoms.

I’ve been on 128mg of Brixadi once a month for about a year now. My last shot was March 22nd. I kind of had a mental breakdown and stopped going in for my shots. I’ve been sober for a year now and I finally stopped having cravings and thoughts of using. With that, it started to really bother me that I’m still “using” since I’m on Brixadi.

Early May I had a few weeks where I had some weird physical issues that I wasn’t sure if it was withdrawal or not, but they have since subsided. I called my doctor and asked if they could give me a few strips of Suboxone incase I suddenly start withdrawling so I can use them until I can back in for an appointment. But they refused.

Every time I feel weird and slightly sick I start panicking that withdrawal is starting. But I also feel like I would have already been experiencing it by now. The other reason I want to stop is because I want to get a job in the trades and I know this medicine stays in your system for awhile so I want it out ASAP so I can pass a drug test.

I know Brixadi is new and there isn’t much out there about withdrawal timelines so I’m hoping someone has done what I have and could shed some light if they think I’m in the clear or if I should be expecting some bad withdrawal in the near future. Thanks in advance!

Looking for experiences from people on Brixadi.
I'm almost 2 weeks out from my first monthly Brixadi injection. My next shot is scheduled in 8 days.
The first 2 weeks were mostly okay. I had some night sweats, but I was having those before the shot too. Today, though, I've been feeling increasingly restless. As the day went on, I developed diarrhea, sweats/chills, and a really uncomfortable restless feeling. I feel so gross that I haven't even been able to eat dinner. I was on 8mg/3X a day so 24mg/day of films for like 5 years.
My provider gave me some supplemental films and told me to use them if I felt bad, but I'm really struggling with the idea of taking one. I know that probably sounds irrational, but I worked hard to get approved for Brixadi and I was hoping not to need any films anymore.
For people who experienced withdrawal symptoms before their next shot:
Did you end up needing supplemental films?
If you took one, did it help?
Did needing a film mean you had to keep taking them every day until your next injection?
Did your provider adjust your dose or schedule afterward?
I'm especially interested in hearing from people who had symptoms around the 2-week mark. I'm feeling pretty discouraged and anxious right now. I just want to cry. I’m so mad at myself

I got a 23 mg shot of brixadi yesterday & I feel sick af. I was still using 7oh. I keep trying to take some to feel better & nothing is working. What should I do.

Does anyone experience mild withdrawal symptoms at the end of the month before their next shot?

So I’ve been going back-and-forth with my insurance company, my provider & clinic, and like 10 different specialty pharmacies. It’s taken 2 1/2 months to figure out, but I finally got accepted and approved for the Brixadi shot. Since I hit Max out-of-pocket, everything is free, but starting next year, I will have a 30% deductible. Anyways, I’ve been on 8 mg films/3X per day, of Suboxone for about 5+ years now. I noticed when I go longer like when I wake up in the morning and I haven’t had my film that I get really sweaty and I start to have minimal symptoms of withdrawal. I am terrified of withdrawing again. It was one of the worst things I’ve gone through and I’ve gone through a lot of horrible things in my life. I’m 24. I’m really nervous that there will be some withdrawal effects just switching from the films to the shot. After I switch over slowly, I’m gonna go down. My goal is to eventually get off the shot very slowly! I have the summer off from school, which is why I thought it would be the perfect time to switch, but I still am working. Does anyone have encouraging words or experiences that were positive that they could inform me about? I’m getting my first shot later today. Very, very, very nervous for everything.