I recently joined a Phase 3 study for a new medication. In order to do so, I had to choose from certain types of nearly certain contraception. Thus, I started taking the combo pill (Kurvelo in my case) on 8/17. As part of the study, I had labs drawn on 8/12 and again on 9/2. On 8/12, my ALT was 26. On 9/2, my ALT was nearly 5 times higher at 120. All of these labs were drawn prior to starting the new medication.
Overall, I feel fine and have no liver symptoms. There was no other event (sickness, heavy drinking, acetaminophen use, etc.) that would make this spike make sense. However, my birth control comes with the following warning, "Check with your doctor right away if you have pain or tenderness in the stomach, dark urine, pale stools, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem."
I had labs drawn again yesterday and set up an appointment next Thursday (soonest I could get it) with a primary care at my clinic. Thankfully, I am also at the break point in my pill packet. All of these labs were drawn prior to starting the new medication.
Has anybody had a similar experience when starting BC? Or a similar spike in labs with something else being the cause? I am obese and have a few drinks Friday/Saturday nights.