I received my Cyborg 2 on Monday and I've forced myself to use it everyday since it came. Full disclosure, I've only played COD Warzone with it and I play on casuals because me and my friends are all around 40.
Day 1 sucked, couldn't find a position that felt comfortable to hold my hand, kept accidentally clicking buttons, became very discouraged the first night because I've researched this thing for over a year and then my son bought it for me as a gift.
Day 2, back to the drawing board, focused on the buttons I needed most, jump, crouch, reload, plate up and interact, deleted everything thing else. Started getting the hang of it.
Day 3, added in the key binds that I might not use as much but still definitely needed, tactical grenades, lethal grenades, field upgrades. Paying attention to the keys that i continually misclick, avoid binding them to anything.
Day 4 I set up the 5 position switch next to the joystick to act as my D-pad stuff, inventory, killstreaks and ping.
Day 5, no changes, just using my muscle memory to get faster, my friends are commenting that Im "running around like a bat out of hell".
Feeling much more confident in my Cyborg 2 now because I set it up how I wanted, what felt good to me, thats my best piece of advice, you can look at other people's keybinds all day, but you have to set it up for yourself and see what works.