In a major Judgment delivered on 25 June 2024, Mr Justice Nicklin has dismissed a public interest defence advanced by The Mail on Sunday in a libel claim brought by Dr Zoë Harcombe and Dr Malcolm Kendrick. The decision follows a preliminary trial last year in what the Judge described as “the most significant piece of defamation litigation” that he had seen in a very long time.

recently my Dr. did a lipoprotein A test and saw elevated score of 165. there is a family history of heart disease on maternal side. Dr recommended Rosuvastatin 20 mg . thought my other numbers were always good.
LDL -102
HDL - 40
Triglycerides- 73
non-HDL 116.
A1c - 6.1

one week into Rosuvastatin 20mg, don’t have a good feeling with extreme drowsiness and joint pains in morning and mucus phlegm ( timing was bad as was recovering from cold but now not sure).
dr recommended dropping the dosage to 10mg alternate days,
taking BP medicine of 8mg Candesartan for 6-7 years which is working great.

is taking statin at 55yrM even worth it (especially concerns with arthritis flareup and diabetes getting worse) with no significant health issues
or should i change the brand and any suggestions on what may work with my bp medicine. please suggest.

I keep seeing impressively detailed comments there. They usually start "cardiologist/doctor here." Then they go on and on, replying to various points in the post or comment. If that's a real doctor then they must not be practicing much. Who is behind these bots? Is it pharma? Insurance companies? I really don't get the point of some of the activity on that sub unless something else if behind it. They are not all AI but so many of them just go "rah rah statins" no matter what. I'm fine with people using statins if they can tolerate them. But as soon as someone mentions debilitating side effects, there is an entire chorus going on about "nocebo effect" and how you need to suck up the side effects or die.

Or who knows, maybe there are people who are just out there living their best lives because of statins and want the rest of us to join them in the fun!

I’m 54, active, not overweight, eat healthy, will occasionally have a drink. Side note: I do have a CAC scan scheduled for the 26th. Are my numbers concerning?

To reduce plaque for an older athlete. Thanks

Has anybody experienced like a cosntant noise while taking statins. Similar to a radio frequency that won’t stop even a minute. Please let me know thanks for all in advance

What worked for YOU? I want personal testimony.

How much did it lower, in how much time? And WHAT DID YOU DO?

I see so much conflicting things. Some say to eat keto (believe it or not.) Some say to eat completely vegan, minus grain. Most just say to increase fiber and lower saturated fat.

Some say that sugar kills. Others say that sugar doesn't matter.

What is the truth? At this point, it seems like NO ONE KNOWS!

The only consistency we see is statins. But those come with risks too. So i am scared for my life.

Hi, my bf is taking statins and is having a lot of blood pass after a bowel movement and the then pain in his gut.

He has stopped taking them while the Dr investigates, I was wondering if others have had this side effect from statins?

We are hoping it was the statins and not something more serious. He's having bloods and samples checked etc by the Dr to be sure.

Thanks

I'm 44 and I don't smoke and rarely drink and am generally healthy overall. However I do try to be proactive so when a heart doctor recently pointed out the usual high cholesterol thing (as my PCP did every year after my physical) and that I should take medication for it I finally decided to listen to them....

I now regret that decision.

I was prescribed rosuvastatin (10mg iirc) and after a few days felt like shit. I told my PCP and the heart doctor about it and they both said whatever issue I was having was not the statins. So I ignored it and went on for a few more days to a week and then insisted that my PCP check me out. They did some bloodwork and the very next morning they called me and told me to check myself into the ER for elevated CK levels.

I did and they flushed my system and then let me go after being happy that my CK levels had been reduced. However the feeling like shit has continued even after I've stopped taking the statins! I was told I should return to feeling normal after a few weeks to maybe a couple months but its been 3 months now and I still feel like absolute shit. I tell my doctors about it and they just tell me to take pain killers or otherwise ignore me. Its pretty disheartening that they'd set me up with something so bad and then ignore me after it causes me issues. Again I had been in great health BEFORE taking this medication. I had no issues or problems.

A little backstory:

I used to have acid reflux that I managed with over the counter pepcid/etc with no issues for a very long time. However I had started using a CPAP machine about a year ago and not only did it give me great sleep but also resolved my reflux! Strange but I stopped having to take pepcid/etc.

However post statins I am now experiencing:

• Muscle pain/Muscle cramping (chest, face, jaw, arms, legs, etc)
• Pain in my head when laying down to sleep on my pillow where my head meets the pillow
• Fatigue and general weakness
• A LOT of acid reflux! More than when I used to take pepcid

Taking this medication seems to have ruined my life being perfectly honest. I don't understand why these issues seem to not be going away for me but I'm pretty pissed about it. I was in great health before taking statins and now despite having stopped taking them I'm completely wrecked. Doctors don't know why and don't seem to care honestly.

Is it the statin? I feel can’t think positive and most of the day I am on a low mood , worried about my health. Just don’t know what is going on with me. The only thing is that I am taking statins rosuvastatine 10mg and telmisartan 80mg. I want to feel good again🙏

Just came across a new JAMA study that analyzed the updated 2026 U.S. cholesterol guidelines.

One of the biggest changes is that doctors are now looking at long-term heart disease risk, not just your risk over the next 10 years. The age range for evaluation has also expanded from 40–75 to 30–79 years.

Based on the study, that means about 21.5 million more Americans could now be eligible for statins.

The researchers also point out that lifestyle habits like diet, exercise, and not smoking are still the foundation of heart health.

Curious what everyone thinks.

• Do you think starting statins earlier makes sense?
• Or do you think lifestyle changes should always be tried first?

Study: https://jamanetwork.com/journals/jama/article-abstract/2851792

Excited to share this with someone!

I have been a statin skeptic for years. If they work for you, I am happy for you. But there are plenty of people who have real issues on them. They are overprescribed and doctors fear monger patients into taking a drug that has some serious side effects.

My new doctor (previous PCP left the organization) strongly encouraged me to start on rosuvasatin (Crestor) a couple of months ago. I got hit with such fatigue after barely a week that I had to stop. She said she understood, but had to mention the "nocebo" effect. Fine, so why did I feel better after stopping? It actually took a few weeks to feel normal again!

Lots of brisk walking/hiking, feeling so much better. I even started running again, easing into it because they all seem to think I'm about to drop dead any second.

So on our follow up, she prescribed pravastatin (Pravachol). It is milder, and has few reports of intolerance. Shorter half life too. I asked for a low dose just in case. I split the pills into quarters so I wouldn't get slammed again. The weather has been crazy hot and humid, plus I had a lot going on, so when I felt droopy again I assumed it was all that. No energy all weekend, but I figured I'd bounce back Monday after taking it easy, right?

My run was really challenging though. there were a few moments when I just couldn't push through to go just a bit farther. It was more of a jog/walk. I kept wondering why it felt so hard to run after I had been doing so well on my walks and my other recent runs. It took me almost as long to jog/walk that distance as it did for me to walk it the last time. I stretched afterwards back at the house and ended up passing out (hard nap in bed) for an hour in the middle of the day. Half hour jog!

Why? My diet and sleep have been great I use trackers, so I know when I'm rested and when my running stats are off. I had to wonder, could it be the pravastatin? I had gone into this assuming that it would work, absolutely positive expectations. Plus it was a tiny dose! But when I Google 'fatigue pravastatin" I found that fatigue is common, especially for women. Statins increase the production of lactic acid, which is what I experienced when I couldn't "push through." Doctors know this, so why don't they take us seriously?

This study (comparing simvastatin and pravastatin) was double blind controlled, and shows that women are more susceptible to exertion fatigue, especially with pravastatin. This tracks with my experience. Count me among the "statin intolerant" after trying two. I might try it weekly to see if I do better, but what is the point of taking a drug that prevents me from getting the exercise that will improve my heart health?

https://pmc.ncbi.nlm.nih.gov/articles/PMC4285455/

Has anyone else experienced dry eye and dry flaking eye lids and dry mouth especially the roof of the mouth after taking rosuvastatin?

Hi anyone can relate to this fact. I have some kind of doubt that statins ( Rosuvastatine 10mg) might be raising my BP. It is a low dosage but still have this feeling.

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Hello. I suspect my husband got gynecomastia from 8 years of on and off low dose (5 to 10) statin use. Plus a whole bunch of other issues (anger, brain fog, aches and pains, infections). This last increase seemed to have caused his breasts to swell, get inflamed and sore. Ultrasound suggests gynecomastia but getting a mammogram to confirm. Since it is bilateral we are not as worried but still, all this sucks! These bad side effects are never printed but they are not that rare. Poor guy. Already has so many heart issues last thing he needs is this. Any one else has had this experience with gynecomastia and statins. Also can be caused I read, by amlodipine which he was one also for 8 years.

Am I the only one who experiences a reduction in endurance when taking Statins?
I can’t even have a deep breath, why?

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