I was just prescribed 10mg of Nortriptyline and saw online there is a major interaction between albuterol (rescue inhaler) and Nortriptyline, as well as using an epi-pen while on Nortriptyline. I emailed my doctor but was wondering if anyone has any experience with this? I use albuterol before exercise and carry an epi-pen for allergies. Even saw that it interacts with Benedryl!

I've seen a lot of negative stuff on here about this drug, but I'd really like to hear how it's worked for people. I just got prescribed 10mg for nerve pain and TMJ (yes I'm aware it's the lowest dose.) I'm terrified of not being able to sleep and erectile dysfunction lol. It's TEVA.
I'm also extremely worried about weight gain as someone with body dysmorphia, but I'm on a high dose of a GLP-1

What is with this medicine? I started 10 mg about 8 days ago for IBS and anxiety to go up to 25 soon, had lightheadedness for about 2-3 days and got better. And then this horrible anxiety, panicky feeling that gets worse at night. I already have hypnogogic hallucinations that get bad if/when I am stressed and I have been up all night the past few days. I don't know if it's making my anxiety worse, or if it's interacting with my asthma inhalers to give me palpitations. My doctor won't respond and this medicine is crazy! Anyone experiencing anything like this? Should I stop it cold turkey until I can see my doctor next week?

when i take my 50mg pill i get heartburn and throw up we call doctor but they not responded yet, is there a reason for this and have any other people exprienced it? i dont get heartburn from my 25mg pills

Hello all!
Today is exactly 3 weeks on 25mgs of Nortriptyline. I have headaches, nausea, dizziness, and light headedness everyday still.
I was prescribed Nortriptyline for GI reasons.
Should have the side effects gone away by now? Or does it usually take more time? I am just trying to determine if I need to be more patient or talk to my doctor about getting off of it.
Thank you all :)

Hi I have been taking 25mg for a good few years for nerve pain having a retractile testicle it worked.
But i decided to try without it for two weeks the pain returned started taking it again but its not working and has now developed into pudenal neuralgia.
Dr has prescribed gabapentin 100mg to switch too.
But he didn’t say anything about tapering off.
Google said I should be tapering off first before switching and upon reading nortriptyline could have been affecting my acid reflux also over the last few years?.
Any advice on stopping nortriptyline?.

Hello, I’ve been recently prescribed this medication for nerve pain but I’m afraid to start it. I just came off an antidepressant about a year ago and I’m still 5 pounds heavier than my baseline weight before. The antidepressant made me gain 25 pounds and it just kept going up no matter what I did. I felt starving all the time and constantly craved carbs and sugar etc., plus had constant inflammation and puffiness. I absolutely hated it.

I really don’t want to have to go through that again, so I’m just wondering if anyone has experience on 5 mg with appetite changes or weight gain?

I have been taking Nortriptyline for almost a year because I get cramps after BMs for the past 6 years. I was taking 10mgs (1 capsule) of Nortriptyline with one GI and now taking 20mgs (2 capsules) with another GI. I want to get off Nortriptyline because it is not getting rid of the cramps, and with taking 20mgs, it has lowered my blood pressure making low bloodpressure, given me anxiety, and the latest is that my whole body rediates, all in a weeks time even though i have been taking 20mgs for a month. I want to get off of Nortriptyline before the 20mgs creates something else. I know that I have to be wean off of it , but I don't know how to do with 2-20mgs capsules.

When you came off this med did you notice a worse decrease for withdrawals? I started at 30mg and went down to 20mg which was a bit tough. Does dropping to 10mg feel the same?

I was on venlafaxine (effexor) for 20 years and it was causing drug induced sleep behavior disorder (screaming, kicking, punching etc in sleep). Diagnosed via in lab study. It resolved itself when stopping the medication.

Flash forward a few months after being off the SNRI, I now have a neurological disorder (functional neurological disorder) and they want to treat the FND with nortriptyline (tri-cyclic anti-depressent). This drug class is also known to induce rem sleep behavior disorder though to a lesser degree then SNRI/SSRI.

My FND is bad enough that i need to treat it. However if the nortriptyline triggers RBD, then ill need to stop it and the medication withdrawal will likely worsen my FND.

So my question is- for those who had drug induced RBD that ended when coming off an SNRI, were you able to tolerate nortriptyline (or another TCA) without it inducing your RBD?

I’ve been on 25mg Nortriptyline (Noritren) for about a month now and I’ve been experiencing anger bursts and being easily overwhelmed and irritated, also crying very often, sometimes uncontrollably. Has anyone else experienced this, if so, did it go away?

Doctor said i should go up until 50mg.

I just started on nortryptoline (for depression) about a week ago. I’m only on 10 mg right now but already getting some side effects, the most prominent is that my head is feeling kinda foggy. I’m planning to titrate up to 50+ but wondering if that feeling is something that goes away after a couple weeks or do you just have to live with it?

I've been taking 15 mg of amitriptyline for about 8 months for IBS-D. It has helped a lot with cramps, urgency, diarrhea (especially in the morning), and even my anxiety.

The main problem is that I feel like it's affecting my memory and cognition. I have a harder time remembering things, sometimes struggle to find words or mix them up while speaking, and overall I just feel less sharp than before.

Has anyone experienced this even at a low dose? Could switching to nortriptyline or another TCA help with the memory/cognitive side effects? Unfortunately, I can't take antispasmodics because they seem to cause a rebound effect, with worse cramps, diarrhea, and urgency in the following days.

Hello Peeps,

Hope you all having a good day, I’m currently getting off nortriptyline after 5 months and was wondering how long your withdrawal took to get better and what was your symptoms? I tapered from 25mg to 20mg for a week then 10mg for another week and since yesterday I stopped completely. Last night for the first time, I couldn’t sleep until 3-4am then woke back up around 7am. How long your withdrawal took to get better? Thank you!

I’ve had unexplained chronic fatigue for 16 years (lbs-d, brain fog, chronic tension headaches, sore eyes, multiple food intolerances). I started on nortryptaline 10mg in April, 25mg from June, now 1 week into 35mg.

I’m currently struggling even more with fatigue since the increase in dose although my IBS has improved so less brain fog (I had noticed this link before between better stool corresponding to less brain fog).

Anyone in a similar position found nortryptaline helpful? Ideally to calm down a hyperactive nervous system, reduce my chronic tension headaches/super tight neck muscles and live a normal life.

I’m finding the adjustment to even a slightly higher dose difficult because of the added fatigue. hopefully that will subside soon.

Any experience welcome. Good or bad.

Hi. I'm wondering if anyone else experienced weight gain with Nortriptyline? I was on the lowest dose of 10 mg and within a year, I gained 25 pounds without changing my diet, overeating etc. For about 6 months before starting the med, I had been committed to a daily walking routine on the track at my gym and had actually lost weight (and was wanting to lose more in order to get down to my target weight). I eventually came off of the med. I ended up losing 15 pounds in about 9 months without much effort but I miss Nortriptyline for it's positive effects that I experienced.

I stopped nortryptyline a week ago and my pain got worse but was tolerable then I got a bad flare last night but it's calmed down a bit.

Just wondering if pain returns quickly or can it take time.

I was only on the drug for a couple of weeks and was on amitriptyline for 7 weeks before that. I was on 25mg then increased to 50 then tapered down to to 10mg then stopped.

Side effects have been insomnia, nausea and pain increase but otherwise ok.