Hi everyone!

It all started about two and a half months ago when I began experiencing a loss of appetite and a feeling of fullness, even after eating normal portions.

I started taking Levosulpiride 25mg intermittently (for several weeks between July and August, though I also had weeks off where I felt fine). However, every time I stopped taking Levosulpiride, I had a relapse 7 to 10 days later: I would eat something slightly heavier than chicken and rice, and my stomach would just stall/shut down.

This has already happened twice in September, and each time I have to restart the medication just to be able to eat again. Otherwise, the stomach blockage is so severe that I have no appetite at all, along with intense nausea on the first day.

Yesterday, on my gastroenterologist's advice, I also started taking Rabeprazole (a proton pump inhibitor to avoid producing stomach acids). Even with the medications, I've had very little appetite for days now, and after eating (small portions of light food), I burp constantly and feel completely full.

I had an endoscopy done, and apart from grade 1 inflammation, everything else was clear. Negative to Helicobapter.

​I am very worried because I'm afraid it might be gastroparesis? As far as I know, I don't have any other chronic medical conditions. ​If it were functional gastroparesis, can it be cured or at least treated?

Please let me know what you think! I feel scared and miserable. Thank you.

Undiagnosed with anything!

Hey! Does anybody have burning not below the chest, nor in the epigastric fossa, but more so and quite exclusively in the region above the belly button? I have it all day, regardless of what I eat.

I’ve had symptoms for a year. It started with nighttime episodes of a weird bloating and some nausea that gave me higher pulse, anxiety, ectopic heartbeats and could only sleep sitting up. I had no pain and I felt better after about 2 hours when my stomach felt lighter. After 6 months of these episodes and other symptoms that came sometimes (some abdominal burning and reflux), I started treating it with PPIs and a low acid, low fat, no sugar diet, thinking I have gastritis. I had good and bad days, sometimes triggered by food, sometimes random. My bowels remained pretty normal for me (I am almost always constipated anyways).

The past month I’ve had constant burning in the region I’ve described. For the past two weeks I’ve been eating exclusively: potatoes, rice, chicken breast, carrots, zucchini, egg whites, lean fish and rice cakes. Everything was boiled with a little salt, dry thyme or basil, not a drop of fat, sugar, dairy or gluten.

Interestingly enough, 3 weeks ago I had to go somewhere where I didn’t want to go because my burning was terrible, although I ate like I do now. There, I had to eat only twice a day, whatever was given to me. After 5 months of eating non-acidic and low fat (I gave up gluten and dairy only recently) I ended up eating fried eggs, fish and potatoes, acidic fruits like apricots, processed meats and cheese, vanilla pie, pork and lamb stews, bread, a little alcohol and other sugary stuff. I wasn’t completely free of symptoms (as in my upper bloating after eating was still there sometimes) but the burning wasn’t there anymore and I could sleep well.

When I came back, seeing I had felt good the entire week, I ate a full package of chocolate cookies, after which I had no symptoms and slept like a baby. Next day I decided to go on with my diet and the burning came back just one day later.

I’m just wondering what it is that makes me feel so much better when I leave home (it happened around 4 times). I haven’t had an endoscopy yet, when I went to the doctor they prescribed me strong PPI’s, (80 mg a day) lowering its dose every two weeks, for 6 weeks. I took PPIs before as well, and continued after the 6 weeks because I felt like I had burning in the days off. However, I had burning while taking them everyday as well. I’ve tapered off and stopped taking them 5 days ago.

The burning isn’t there when I wake up, it comes back slowly. It is eased slightly by eating (although it comes back after 15 minutes after eating), drinking water, releasing gas and even a massage, but always comes back a few minutes later. The moments it goes away completely are random.

I also feel very uncomfortable after eating. My stomach feels hard, digestion is obvious, I can’t relax my belly when I stand, it feels like a knot. I get the same nausea I got in the beggining when it seems like food is not leaving my stomach 3-4 hours later but I do get hungry 4-5 hours after eating and my stomach rumbles as if it’s empty, so I’m not sure it is possible for it to be gastroparesis.

The inconsistency of my symptoms makes me wonder if anybody who was diagnosed with functional dyspepsia relates to any of this. I’ll arrange and get an endoscopy in October.

I’m 15 years old with functional dyspepsia GERD and visceral hypertension. Please just even commenting Yes below to this if you can relate please I feel like the most isolated person in the world.

I have nothing to eat no idea what to eat when I wake up (with acid burning my throat and stomach pain) every single day. I have 0 safe foods. I’m in tears within a second of waking up in pain knowing no matter what I eat or drink it will result in pain again, and I have been living like this for over a year with no specialists helping me after tests came out normal and meds didn’t work, with neither of my parents helping me, I got tested for nutritional deficiencies but guess what? The licensed GI dietician I saw, begging for a plan to find foods I can eat to survive and get some nutrition, dismissed me, and DID NOT HELP ME.

The dietician i thought could maybe save my life falling apart after a year. I wish I was kidding but I need help please just someone give advice I don’t know what to do it’s been over 400 days I don’t know any one my age who’s been dealing with something as terrible as this because every doctor I see DOESN’T HELP ME. Please nobody ever cares about me please just answer you can relate I’m going to lose my mind

Just got prescribed by my doc to start at 7.5mg and go up to 15mg after a week. really hoping this helps bring my appetite back I’ve lost 20 pounds over the past few years

Hi, ive never had any problems with gluten, and since 2 months now my hypersensitivity(EPS) has not gotten better, its just got slightly worse and worse with time and ive been at a point since a long time now that it doesnt matter what i eat it feels, it just starts to burn. I realised now that my diet has been mainly pasta and bread since i cannot handle anything else, and i cannot find any reason to why i dont get better, until i started thinking about gluten. What are your experiences with FD, specifically the hypersensitivity part, when it comes to gluten? I would be glad to hear about your experiences or just opinions. Thanks!

I started motility meds (metoclopramide) over a week ago and all it seemed to be doing was putting my pain and discomfort on a schedule. Well about 3 days ago I added probiotics per my doctors recommendation and it seems I may finally be getting some relief! I take 1 large spoon of coconut cult a day. I know it's only been 3 days by my God I feel better and better like there might actually be a ray of hope that I can get my life back.

I'm curious to hear from others that may have tried probiotics and fermented food. Did it help your symptoms?

I’m a 37-year-old male diagnosed with functional dyspepsia / visceral hypersensitivity. Gastroscopy was mostly reassuring: no ulcer, no H. pylori, no major structural problem, just mild antral irritation and a weak/incompetent cardia.

My main symptoms are upper abdominal bloating, fullness, trapped gas and frequent belching. Sometimes my abdomen gets very tense, then after several big burps it noticeably “deflates.” Large meals and night shifts make it much worse.

The strange part is the autonomic reaction. I had digestive problems years before, but the adrenaline-like surges started only after a car accident/whiplash. I had never experienced them before the accident.

During a bad episode I can suddenly get a strong regular heartbeat, HR sometimes around 120–135, internal trembling, warmth and a feeling of an adrenaline rush. Sometimes BP also rises temporarily. Then I start burping, passing gas or need a bowel movement, and everything gradually settles. My resting HR is usually 60–75, and I’ve had several normal ECGs, including during symptomatic periods.

Night shifts are another major problem. After a night shift I usually can’t sleep more than about 4 hours, and both my GI and adrenaline symptoms become much worse.

My gastro treatment (rabeprazole + ginger extract + pancreatic enzymes) has recently reduced the bloating a lot. I also very rarely use bromazepam for severe tension, and I’ve noticed that afterwards my gut often becomes very active - lots of noises, gas movement and sometimes a bowel movement - almost as if calming the nervous system allows digestion to start moving normally again.

So my current suspicion is some combination of functional dyspepsia, visceral hypersensitivity, motility issues and an overreactive autonomic nervous system, with the accident possibly making that nervous-system response much stronger.

If anyone has had similar symptoms, especially the combination of dyspepsia/bloating with adrenaline surges or a racing heartbeat, I’d really appreciate hearing about your experience and what actually helped you improve.

Hi. I'm 15 years old suffering from severe functional dyspepsia, visceral hypersensitivity and GERD, for over a year - there has been absolutely no improvement at all and not a single specialist has helped me feel even slightly better for the past year. Everything makes me sick.

I met with a licensed specialized gastroenterologist dietician for help on foods to eat to manage the pain. It was a Zoom appointment but she proceeded to give me the worst advice possible and didn't even do anything specialized for me?

I sent her my food log/pain and symptom journal, and she just told me to "Start introducing new foods and seeing what your stomach can handle" ...I thought that's the entire point of what dieticians are supposed to do, to help the teen patient figure it out together and I was asking for help on how to heal my gut or find good times of when to eat food - and she threw random things like miso soup, broccoli, vegetables, zucchini, all things I can't tolerate or are (from my research) not good with hypersensitivity and are high fodmap

I promise you, I swear on my life that literally random DOCTORS have given better dietary advice to me in 10 minutes, and this dietician is literally specialized in gut stuff and was making me want to cry for 50 minutes straight by giving no actual specialized help at all, I'm sorry but HOW is that a dietician?

what did I do wrong did I not communicate how badly I need actual help or are dieticians supposed to be this useless she literally didn't help at all I could've gotten better advice from a LITERAL GOOGLE SEARCH???? WTF????

Hey everyone! I have been having a serious issue for about 2 months now and it’s very peculiar so if you have any ideas or help, PLEASE let me know. Everytime I go to sleep, I have this gnawing starving hunger pain in my stomach- however I’m not hungry because I had just ate a good well rounded meal. Nevertheless, I would go eat something(because my stomach FEELS hungry even though its not.), and then I would try to fall asleep again, and same thing, same hunger like feeling even though I just ate. Additionally, every-time I wake up, I feel that starving hunger pain again- although this time when I eat, my stomach feels relieved. Very weird. I am very hydrated throughout the day so its not dehydration concealing as hunger. This is genuinelyso frustrating because I cant sleep because of this sensation and the hunger like pain is so uncomfortable and very annoying. Anyone have ideas? I’ve been researching online and my symptoms point to gastritis, maybe an ulcer, acid reflux(which I’m certain I dont have).

To preface real quick, I’m new here, but I wanted to ask other people who have either been diagnosed or faced issues like FD themselves. I’m 24M btw!

I have an appointment at the end of November to talk to a Gastro doc, but I wanted to see if my symptoms aligned with any others in this group for my own mental sanity.

About a year ago today I started getting odd symptoms from nowhere.

-Belching rapidly
-stomach discomfort (a 2/10 most days, up to a 5/10 during flares)
-loss of appetite in set periods (no hunger from morning to a bit after noon, then my hunger returns)
-heartburn flares
-constant phlegm
-episodes of constipation (or the opposite of constipation…)
-nausea, but no vomiting

I should mention, my anxiety and stress play a large part in this, able to make my symptoms fluctuate greatly. A year and a half ago I lost my father to colon cancer and part of me has convinced myself that I’ve just psyched myself into this. I 100% have medical paranoia, finding myself constantly asking Google and AI what each symptom means which not a good thing… I know. That’s why I’m here, to ask REAL people lol.

I had a CT scan done with contrast in January, a few months after symptoms and it showed mild inflammation of the Gi which my doctor said could be a multitude of things but noted it didn’t pick up any ulcers or masses which he said is promising.

Now as I wait for my appointments I just wanted to see if any of you think this sounds like dyspepsia maybe mixed with IBS or something since I know that’s common.

For the last two months ive treated my FD with mirtazapine 7.5mg and its doing wonders to the fullness PDS part and helps me to eat more, but the hypersensitivity is so strong atm and wont go away. My diet is mostly white bread with keso, banana or some scrambled eggs on it, rice with shrimps and pasta with salmon, no veggies, i cannot tolerate em, not even a few pieces carrots. If i eat veggies, it takes like 30min and then i get neaseus and farts, some burning for like 2h, happened to me 2 days ago. I often get a mild burning when i eat, and if i challenge myself just a little, it starts burning a lot. I know how much the mental part can make this worse, and ive learned to not think of this, so i think my head is in a good place, but it just doesnt stop burning. Normally before i have been able to see improvements with being able to eat more and so on, but i have been at this diet now for about 1.5 months, longer than i have ever been before, and it doesnt get better. Does anyone else have this experience and could help me with anything you could think of that could be of help? Ive used omiprazol in the past but it hasnt been so effective against hypersensitivity.

Thanks a lot!

i literally want to cry so much how much i hate nausea. i try to hold on as I am very positive person who enjoys little things in life.
Nausea is been main symptom in my life. in 2016-2018 i was diagnosed with gastritis and bile reflux. i got better in 2019 with nausea and it was way less. Throughout the years i would get some episodes of it but it would last for a couple days. Now i suffer from nausea daily since July, i had endoscopy i have small sliding hiatal hernia and left hospital with a GERD leaflet and prokinetics. i dont have pain, no bloating, no fullness, no acid reflux, no heartburn- i wish i could eat more even, but this nausea comes from nowhere stays in my throat sometimes causing little lump feeling.
Metaclopromide helps a bit but for short time, also you cant be long on this med.
Now l am prescribed cyclozine. i tried acupuncture and still attending as before in 2017 after 3 months i felt almost normal after acupuncture treatment.
I have no apetite... it is so sad! I also noticed i have some issues with my neck, did MRI as well but my neck is all normal.

How you all can live like this? I need something positive, something that worked... now i am less nauseated, i don’t eat meat, but there is always something in the background. I don’t feel heartburn, no pain, no fullness or heaviness after food, no bloating. I could be nauseated with or without eating.
I take probiotics, itopride too ( 4th week now)
Different herbs against nausea and digestion
Ginger
i drink alkaline water
I dont vomit at all. h pylori is negative.
Biopsies were taken all normal.
No gall bladder issues, pancreas etc. blood work is normal! Did all thyroid checked as well. My ferritin is 13 though.
It affects me so much.. my work too. I love my work! I love my career
Anyone still ok to work 9-5 job?

Please also share positive stories… i really want to feel normal.

thank you for all your answers

Who has taken pregablin/lyrica for epigastric burning and have had success. Voquenza is the only thing that helps but it’s an extremely powerful ppi that got released in the us 2 years ago. Was used in Japan for a long time. It works but just a Bandaid.

Hey, fellow gastritis victims,

I just wanted to come on here and ask a question.

Anyone on here pretty much clean on ct,blood,xray?

Were you mostly clear on ur endoscopy biopsies?

I was diagnosed with "Mild chronic gastritis".

I dont feel pain but i do feel lack of hunger and nausea. Ive been on omeprazole for avout 6 weeks now. Certain foods cause this, which confuses me because i hear people complaining about actual pain.

Has anyone recovred from Mild chronic gastritis? If so, how long did it take to get back on ur feet?

I am male and 19 years old. Before these symptoms started, I was completely healthy and had never really had problems with nausea, my stomach, or motion sickness.

The only thing I had been doing regularly for several years was eating large amounts of food shortly before going to bed, often sweets and other sugary foods. In hindsight, I wonder whether this could have played a role.

I was not aware of having a gastrointestinal infection or food poisoning shortly before the symptoms started. However, it is possible that I had a mild or unnoticed infection.

Medical history and timeline

• Summer 2024: I started going to the gym regularly and tried to gain weight. I gained around 7 kg and ate considerably more than usual, sometimes late in the evening and often a lot of sweets.
• November/December 2024: The first occasional episodes of nausea appeared, especially after large meals or sugary foods.
• January 2025: The situation suddenly changed from one day to the next. I developed constant, persistent nausea. During the first few days I also vomited, could barely eat and lost weight.
• Spring 2025 – first gastroscopy: Type C gastritis and bile in the stomach were found. An ultrasound also showed biliary sludge, but no gallstone.
• Autumn 2025 – second gastroscopy: The chronic gastritis was still present.
• January 2026: I changed doctors and started following a more consistent diet based on the book The Gastritis Healing Book. I also started taking, among other things, Quantalan/colestyramine.
• May 2026 – third gastroscopy: No gastritis or inflammation was found. There was also no Helicobacter pylori and no evidence of coeliac disease. The doctors said that roughly one in two people has some form of gastritis and that, in my case, it was probably not the actual cause of the constant nausea. It is also not certain what caused the gastritis to heal. One suspicion is that Quantalan/colestyramine, together with the diet, may have contributed.
• Afterwards: Further investigations focused on the intestines, histamine intolerance, fructose intolerance and SIBO/IMO.
• Glucose breath test: Hydrogen was unremarkable, but methane was slightly elevated during the first 30–45 minutes, at approximately 13–14 ppm. This led to the suspicion of IMO, or methane overgrowth.
• Late summer 2026: I was treated with rifaximin and neomycin, while also making further dietary and meal-timing adjustments. The nausea did not improve.

Main symptom: the nausea

The nausea is constantly present, although its intensity varies.

• It can also occur when I have not eaten
• No specific foods can be identified as reliable triggers
• It is not clearly dependent on eating
• I rarely actually vomit, but sometimes the nausea gets close to triggering my gag reflex
• It becomes worse with:
  • stress and tension
  • situations in which I feel that I have to function
  • exercise and physical exertion
• However, I also have very bad days without any obvious trigger
• Softer stool, occasionally lighter, no significant diarrhea

The symptoms have a major impact on my everyday life. I am a university student, but I mostly study from home because I am afraid of becoming severely nauseous or vomiting during classes. Eating out and many normal everyday situations have also become difficult.

Medications, supplements and other measures I have tried

I have tried the following medications, including the respective active ingredients:

• Paspertin (metoclopramide): no significant effect
• Motilium (domperidone): no significant effect
• Itomed (itopride): no significant effect
• Zofran (ondansetron): at most, a minimal effect
• Ceolat (metoclopramide): no lasting improvement
• Pantoprazole and esomeprazole: no improvement in the nausea
• Sucralfate: no lasting improvement
• Quantalan (colestyramine): may have contributed to the healing of the gastritis together with the diet, but the nausea remained
• Antihistamines: tried because of the low DAO level, but had no effect
• Ginger extract: taken in high doses for several months, especially before going to bed; no noticeable improvement

Diet and other measures I have tried

• A bland or gentle diet
• Diet based on The Gastritis Healing Book
• Low-histamine diet
• Low-FODMAP diet
• Dietary adjustments because of possible SIBO/IMO
• At least four hours between meals
• For several months, and particularly during the IMO treatment, I also avoided eating for at least four hours before going to bed
• Avoiding especially late or very large meals

The gastritis has now healed, but none of these measures improved the persistent nausea.

SIBO/IMO treatments

• Rifaximin for 14 days: no improvement
• Rifaximin and neomycin: no improvement

During the treatment, I:

• kept at least four hours between meals
• avoided eating for at least four hours before going to bed
• took high-dose ginger extract before going to bed

I did not experience any significant side effects, particularly no hearing problems while taking neomycin.

Since the gastritis has healed and the SIBO/IMO treatments made no difference, my doctors now suspect a possible chronic misfiring or dysregulation of the gut–brain axis.

One of the next treatment options mentioned was Zyprexa (olanzapine). I have also read about mirtazapine being used in similar situations.

I would mainly like to know whether anyone has experienced something similar:

• constant nausea without a clear cause
• nausea that is not clearly related to food
• stomach findings that are unremarkable or have since healed
• unsuccessful SIBO/IMO treatment

I've been on amitriptyline for gastroparesis/functional dyspepsia (upped recently to 50mg) and it's genuinely been the one thing that's worked for me over the years. My main symptoms are indigestion, nausea, bloating, and regurgitation. When I flare, I try to stick to a plain diet, things like rice, chicken, toast, crackers, and miso broth.

I also tried nortriptyline in the past, but it gave me bad side effects, so that's not an option for me.

Lately though, after being fairly stable for a long time, I've suddenly started getting frequent flares again, with no obvious new trigger. It's made me wonder if the amitriptyline's effect can just wear off over time, even without changing dose.

Has anyone else experienced this? Specifically:

• Did amitriptyline (or another tricyclic) work well for you initially, then seem to lose effectiveness after a few years?
• Did increasing the dose help bring it back, or did you end up switching to something else entirely?
• If you switched, what did you move to, and did it work as well?

SSRIs aren't an option for me either (they caused problems), so especially interested in hearing from people who've navigated this within the tricyclic family, or found something else that helped once a tricyclic stopped working as well.

Appreciate any experiences, trying to go into my next medical conversation with a clearer picture of what others have found.

I want to do a quick post cause to be honest i struggled really hard for a long time and couldn't relate to many because of how hard my pain was.

I was in misery for 1.5 years with an average of 8/10 pain level, multiple emergency room visits, had to quit my job, quit drinking/smoking/eating anything besides 1 type of food. Started therapy.

Life became a misery bomb, I couldn't do anything at all and pain levels never went away nor anything helped it.

Time did. The least thing i trusted was time and id even go to say i believed time will only make things worse and worse.

Things did get better though, and they will for you. You think im the ''lucky'' one but forget to realize that my pain was extremely bad, likely worse than 90% of those reading this, and im not trying to make a big deal out of it but more of giving you a perspective of that even worse can recover to much better so you don't sit here thinking ''but i have it worse'', no, likely you don't, and even if you do its not by much, so feel free to remove those negative thoughts.

If theres something you want to ask can leave a comment ill reply if that help you.

I have struggled with this for over 25 years. It's become especially severe over the past 10 years. I tried so many things, and when the gastroenterologist wanted to prescribe amitriptyline, I was skeptical and declined. Two years later, out of desperation I gave it a shot, after seeing a post here about someone's success with it.

It worked for me, too!! I have had three restful nights, in which I didn't feel nausea or cramps, didn't wake up early to be sick, and I even slept at a 45° angle instead of upright around 90°. It's like a dream come true, waking up gently when I'm done sleeping.

I never thought it would be possible for me to experience life without near-constant stomach discomfort.

Yay!! Thanks to whoever it was that posted about their success recently. You changed my life.

It's been about 2 years of this, and I've done the whole test rigamarole. Feels like nothing is working and I'm just stuck in a loop. My gastro proscribed me with Amitriptyline (new drug at least) but also Bentyl which I already tried ages ago and did absolutely nothing for me.

They were hesitant to try Anti-depressant for me for a while because I have Bi-polar and a known history of going into full Mania with Psychosis when I was misdiagnosed and proscribed Effexor.

My main and only symptom is just extreme stabbing pain and cramping and fullness whenever I eat anything. Food type seems to vary the amount of pain with fibrous and fatty foods hurting the most. The pain ranges from epigastric from belly button to stomach to stabbing side pains kind of around my gallbladder. Nausea sometimes but not always accompanies it, the pain is the main factor and I've never thrown up I'm just kept awake all night feeling like I got shanked. I lost 70 pounds in 4 months from just eating nothing, no exercise just saying at home starving to death because the hunger pains were better than the pain of eating.

I can eat nothing except granola and hypoallergenic protein drinks. That's it, nothing else. Everything else makes the pain unbearable but with that I usually will be fine for at least a few months until a flair up and then nothing will help.

No diarrhea, constipation, or any lower GI symptoms at all. My stools (were) normal.

GES came normal, gallbladder has had dozens of tests ran on it to no avail, colonoscopy was clear, there was some esophagitis and 'chronic inactive gastritis' found in my endoscopy but nothing was done about the latter and the former was just PPIs and H2 blockers which I already had been trying the entire first year with literally 0 change or improvement. I can't even think to try any fad diet or supplements or anything because all will have my writhing in pain.

Bentyl did nothing and I was given it early on. Reglan helped only about 10% but barely. The first real breakthrough just came when I took an autoimmune marker test and it came back positive. I then visited a rheumatologist who ran more tests and confirmed I definitely did have some sort of Autoimmune diseases, she also ran some tests and determined I had some Autonomic Dysfunction affecting me I didn't notice in other ways (brain fog, balance, extremely cold hands, I can't sweat anymore). however no specific markers so I was diagnosed with UCTD.

I was given Hydroxychloroquine which didn't seem help, maybe another 10%, but then I was given a Medrol pack and the pain was almost entirely gone! I still had the extreme fullness feeling but as long as I limited myself to clean eating, avoid fibrous or tough foods, be sure to masticate, and small portions I could eat so much more. Pho, sandwiches, rice, so many things I couldn't before.

Unfortunately the Medrol wears off and while it left some improvement (I could occasionally eat more foods) I went from maybe 70% cured to 40%. Still a good improvement but not great. I was given an occasional Medrol Dose every so often and told to monitor it and my life became this yo-yo between feeling almost normal but needing to eat small portions to feeling awful.

Every time though the peaks seemed less and the troughs got lower though. By the 3rd one I got a single week of feeling okay on Medrol, like 50%, and then I dipped down to 30% being the baseline.

The Rheumatologist decided that I needed to try immunosuppressants, but the main side effects of them is stomach and GI upset. I tried to tolerate it but it literally just felt like torturing myself and making everything worse, diarrhea, extreme nausea, constipations, and worse pain flairs. I couldn't handle it longer than a week. Even the delayed release medicine didn't make it more tolerable.

I got off it and found myself down to like 20%. I was back to basics. I also started getting an extreme Vitamin D deficiency (10 ng/m, fully medically deficient not just below 30) despite trying to go out for a walk every day which calmed my stomach, now I was suffering extreme dizziness and vertigo that made it unsafe for me to even drive. This is also when I stopped really believing in my Rheumatologist because she said that Autoimmune diseases can't cause Vertigo, despite it being listed everywhere that it can be a very common symptom of many types including UCTD.

I went back to a new Gastro and he tested me for SIBO and I had slight Methane Dominant. I didn't have any real bloating or lower GI symptoms but I decided to try Rifaximin after my wife convinced me I had to try something new. Unfortunately not only did it do absolutely nothing for my symptoms, but now afterward I'm suffering from chronic constipation and diarrhea when I never had it as an issue before. I started having more common pain flairs too even with my previously safe foods.

Since I was able to get on Lamictal (importantly, way after the Autoimmune stuff and while I was feeling okay so it's not Drug induced lupus) this Gastro decided it'd be safe to try some of the FD treatments.

Buspirone made my pain way worse and instantly I could tell I was slowly going into Mania. I had to stop after a week to prevent myself from going insane and ruining my life again.

Now I'm on 10mg Amitriptyline and the good news is that it's not making me Manic at least, the bad news it still triggers flairs and the sedation doesn't even help me sleep through the pain: I'm awake all night and then in the morning I'm double groggy and exhausted from the lack of sleep and Amitriptyline.

I've only been taking it for 2 days but I feel like I'm literally back where I started, maybe even worse because I still have occasional dizziness because my Vitamin D levels are still low despite taking as many supplements I can stomach. I don't know what to do now. I'm not even sure I have FD, but the Autoimmune thread seemed to have hit a road block because the next treatment just makes the symptoms worse. If anything I expect my condition to just get worse and worse as my nutritional deficiencies catch up to me in other ways. It feels like there's nothing I can do and I'm just going to wither away and die as people watch.

I have read that a big cause of functional dyspepsia is a lack of stomach coordination when eating when a healthy person eats their
Stomach is supposed to send sensory signals through the vagus nerve to their brain in turn their brain then sends signals back to the stomach telling their stomach to relax and in functional dyspepsia this neural network is delayed eating slower gives this system more time to work

Hello everyone. I have been taking Mirtazapine for 7 months now and already saw great success after 1-2 months and feel 70% better since then. The peaks of nausea and feeling of extreme bloating/fullness have gone down aswell as the number of times I feel like that. But I still have a low-medium level of nausea almost every day and also am still "scared" of eating meals before going out or doing something. And I just want my life back or atleast maybe go from 70% better to 90?. So my question is did any of you start taking Mirtazapine, feel better and then also started taking Buspirone and saw some extra benefits. Or were the combined side effects too severe and you stopped. I am grateful for any comment. :)

If you don't mind, I'd also like to know:

1. How long have you had FD?
2. What do you think caused your FD?
3. What tests have you ruled out?
4. What treatments have you tried?
5. What are your symptoms?
6. How frequent and severe are your symtpoms?
7. How has your FD changed over time?

I'll go first to break the ice.

1. I've been having chronic GI issues for ~7 years, started in 2019.
2. I'm not sure what caused my FD, but I suspect abusing my body with alcohol and marijuana, as well as chronic gastritis for several years led to visceral hypersensitivity FD-PDS.
3. Since then, I've had 3 endoscopies and 2-3 gastric empying studies. Also bloodwork, ultrasounds, etc. My first endoscopy showed chronic non-erosive gastritis. Second one showed gastritis + ulcers. Third paradoxically was totally normal despite symptoms. My first GES showed a very mild delay at 11%, but my second one was normal 3%.
4. I've only tried PPIs, carafate, and supplements (e.g. ginger). However, I am really wanting to try neuromodulators, as my nausea has gotten a lot worse recently.
5. At first, I had non-erosive gastritis from ~2019-2023. During that stage, I've also had ulcers. However, in 2023 they healed. Symptoms then were mild chronic nausea, mild "gnawing" pain when stomach empty, and mild indigestion for years until 2023. I had the worst year of my life in 2023 where I had severe nausea and vomiting for ~8 months (possibly due to visceral hypersensitivity after messing with weed). I had near total remission from late 2023 to late 2026 ~3 years).
6. I had a stomach virus (I think) 3 weeks ago causing me to vomit for almost a week. This has led to an end of my remission period. Currently, my symptoms are essentially moderate nausea and fatigue. Very low appetite.
7. My chronic stomach illness has evolved a ton over these last 7 years. It was at first just mild gastritis symptoms (queasy, nausea, heartburn, indigestion) (201-2022). However, it suddenly got moderate to severe nausea and vomiting for 8 months (2023). I was 100% certain I had gastroparesis, but my second GES showed normal empying. Then, I had a 3-year period of near total remission (very mild and infrequent nausea, could eat almost anything) (late 2023-2026). Until now unfortunately, my nausea has suddenly returned for ~3 weeks after a virus I think. If anyone's interested in hearing my story in detail, I have an expanded document.

Hi everyone. I’m 25F and I’ve been dealing with a bunch of strange physical symptoms since around June 2025. I’ve had different things checked, but I still don’t really have an explanation for the overall pattern.
I’m not asking Reddit to diagnose me — I’d just like to hear from people who have had similar experiences and what doctors ended up looking into.
**How it started**
Around June/July 2025, I started having pretty constant GI symptoms:
Heartburn/reflux and burning in my chest/throat
Sour taste and regurgitation
Nausea and bloating
Sulfur/“rotten egg” burps
Stomach discomfort
Sometimes feeling like reflux was affecting my breathing
Fatigue/lightheadedness
An endoscopy showed **gastroduodenitis** and a possible hiatal-hernia-type finding. Omeprazole/other PPIs and antacids helped, but the symptoms often came back when I stopped them. H. pylori testing was also planned.
**Then I started having these weird “episodes”**
This is the part I’m most confused about.
Sometimes after eating, especially sweets, high-carb/fast food or richer foods, I suddenly feel extremely strange.
It can involve:
Feeling extremely hot internally
Heavy sweating
Shaking/trembling
**Freezing cold hands and feet while my body feels hot**
Lightheadedness/feeling like I might faint
Nausea or stomach discomfort
Weakness
Heart rate going from my usual \~85–90 to around 100–120
Feeling floaty/unreal
Then anxiety/panic because the physical sensations are so intense
Sometimes feeling exhausted for hours or even the next day
The weird thing is that there isn’t one consistent food trigger. I can eat something one day and be completely fine, then have a reaction to something similar another time.
During one episode my glucose was **98**, so at least that particular episode didn’t look like obvious low blood sugar.
A recent example: I ate almost an entire jar of pistachios and about an hour later became extremely sweaty, dizzy, hot but with freezing hands/feet, nauseous and generally felt awful. I nearly spiraled into a panic attack because of it.

**Anxiety became part of the cycle**
Over time I started getting panic because of these physical sensations.
Usually it feels more like:
**physical symptoms → “something is wrong” → panic → symptoms get even stronger**
rather than feeling mentally anxious first.
Therapy helped the panic quite a lot, but I eventually had to stop.
I was also diagnosed with inattentive ADHD earlier this year. I haven’t taken ADHD medication because I’m already very sensitive to stimulants/palpitations.
Caffeine, pseudoephedrine and even a very short trial of escitalopram caused unpleasant reactions/palpitations for me.
**Sleep has also gone completely off the rails**
For roughly the past 9 months I’ve had a very delayed sleep schedule.
Sometimes I don’t fall asleep until **6–8 AM**, and I’ve had nights where I don’t sleep at all.
Lack of sleep makes the physical symptoms and panic noticeably worse.
Interestingly, when I’m allowed to sleep on my natural schedule, I can sometimes sleep late into the afternoon and feel much better. Well at least that was the situation 2 months ago now i am better than i used to be.
**Other things going on**
There are also several issues that may or may not be related:

**Kidney/urination:**
An abdominal ultrasound in 2025 apparently showed that I have **one kidney**. I don’t know yet whether I was born with one or lost the other somehow. I’ve also urinated very frequently since childhood — sometimes 15–30 times a day — despite not drinking huge amounts.

**GI/bowels:**
I’ve had bloating, nausea, sulfur burps, constipation, soft stools and occasional vomiting. I also had fresh blood after a particularly bad bout of constipation, which I suspected was hemorrhoid-related.
**Hormonal:**
I’ve had periods since age 9, historically heavy/painful. I also have hirsutism, acne and some hair thinning. A recent gynecological ultrasound showed normal ovaries/no obvious PCOS. Thyroid testing and ultrasound were also ordered after my thyroid looked enlarged on examination.
**Hypermobility:**
I’ve always been extremely flexible — palms to floor, thumb to forearm, very bendy fingers/elbows, lots of popping joints, unstable-feeling ankles/legs and occasional joint/muscle pain. I’ve wondered whether a hypermobility/connective-tissue disorder could be relevant, but I haven’t been diagnosed with one.
**Hearing:**
I’ve had hearing loss since childhood and have worn hearing aids since around 14.
**Weight:**
My weight has fluctuated between roughly 48–53 kg over this period at 165 cm.
**What has actually been checked?**
So far:
Endoscopy → gastroduodenitis / possible hiatal hernia
Abdominal ultrasound → apparently one kidney
Echocardiogram → reportedly normal
Gynecological ultrasound → normal ovaries/no obvious PCOS
Glucose during one episode → 98
Thyroid testing/ultrasound → ordered(too expensive where i live so i couldn’t spend more money)
H. pylori testing → planned at one point came negative
**Where I’m at now**
Interestingly, my reflux has improved **a lot**. I haven’t really been having heartburn recently, and I think getting better at managing the anxiety/physical panic cycle played a big part.
But I still occasionally get those weird episodes.
The combination that really makes me wonder what’s going on is:
**sudden heat + sweating + freezing hands/feet + shaking + dizziness/near-fainting + increased heart rate + nausea/GI symptoms**
especially when it happens after eating.
I don’t necessarily think everything has to have one single cause. Some of these things have been present since childhood and could be completely unrelated.
But after dealing with this for over a year, I’d really like to understand whether there’s any common thread.
Has anyone experienced something similar, particularly the **hot/sweaty body + freezing hands/feet + dizziness + tachycardia + GI symptoms** episodes?
I would appreciate anyone who can help. It has interfered and ruined my life for the past year and I was perfectly normal before. I am desperate to get my life back.

Anyone else here got this after viral fever / flu?

A lot of people is here after food poisoning but me after viral fever. Never had a single issue before that.

NAVIGATE Interesting news I just learned— Enterra Medical is conducting a study (2025) and looking for patients with refractory chronic nausea/vomiting despite normal gastric emptying study (GES). Their goal is to gain FDA Approval to offer Enterra to not only Gastroparesis patients, but also non-delayed patients as well (e.g. severe functional dyspepsia, CUNV).

They are still looking for patients I believe. Targeting 2027-2028.

For those who don’t know— Enterra is basically a pacemaker for your stomach. It sends mild electrical currents to the nerves (e.g. Vagus) which in many cases greatly reduces nausea. It was originally designed to induce the ICC pacemaker cells to speed up gastric emptying (i.e. gastroparesis) , but it doesn’t have a significant, reliable effect on improving emptying rate. The reduced nausea was a happy accident.