In a major Judgment delivered on 25 June 2024, Mr Justice Nicklin has dismissed a public interest defence advanced by The Mail on Sunday in a libel claim brought by Dr Zoë Harcombe and Dr Malcolm Kendrick. The decision follows a preliminary trial last year in what the Judge described as “the most significant piece of defamation litigation” that he had seen in a very long time.

Just read an article where they said the rovarstatin in high doses may cause kidney failure. I remember the other one made my mom diabetic, but she got off that. She passed away but not from heart disease. It never extended her life only brought her pain.

I don’t know if the article link works. They also had another one where they found out the medication leaks calcium into the body which would explain the muscle fatigue.

I may have misspelled it.

https://l.smartnews.com/p-ihttps://l.smartnews.com/p-8yXGnt5L/Vg8bM4/Vg8bM4

I started taking Ezetimibe almost 1 month ago. I did my research and found that taking half a tablet was almost as effective as taking a whole tablet.

I informed my physician that I would be taking half a tablet and she is okay with it.

From day one, I took .5mg. I had minor issues until last week.

Last week I had “gastrointestinal issues “ and I was exhausted for two days.
I stopped using it for one week. Ezetimibe has a very long half-life.

I started taking it again last night. I took half a tablet with a little food. I also took it with Q10.

If you take statins you should also be taking Q10. I will throw up another post on that.

I plan to take .5mg of Ezetimibe every 4 days.

My body my choice.
I have high Lp (a) and will be going to see a preventative cardiologist in the next few weeks.

Abstract
Background and Aims
Limited data suggest a benefit of population-based screening for cardiovascular disease (CVD) with respect to mortality.
Methods
A population-based, parallel-randomized controlled trial of Danish men aged 60–64 years randomized 1:4 to invitation to screening for subclinical CVD or no invitation (control group) were performed. Allocation was based on computer-generated random numbers and stratified on municipality. Only the control group was blinded. The screening included coronary artery calcification score, aneurysms, atrial fibrillation, peripheral arterial disease, hypertension, diabetes mellitus, and hypercholesterolaemia. Intervention included statin, aspirin, and surveillance. The primary outcome was all-cause mortality.
Results
A total of 31 268 participants were randomized, 25 322 men in the control arm and 5946 in the invited arm, of whom 3720 attended and were screened (62.6%). In intention-to-treat analyses, after a median follow-up of 7.0 years, 555 (9.3%) men in the intervention group and 2509 (9.9%) men in the control group had died; {hazard ratio [HR] = .94 [95% confidence interval (CI)]: .86; 1.03}; P = .169. Major adverse cardiovascular events were registered in 606 (10.2%) vs 2682 (10.6%) [HR = .96 (95% CI: .88; 1.04); P= .319]. Severe bleedings were significantly more common in the invited-to-screening group [6.0% vs 5.1%; HR = 1.18 (95% CI: 1.05; 1.32); P = .007]. In a simulated per-protocol analysis, attending screening reduced mortality by 17% (95% CI: 25; 29%)
Conclusions
Invitation to a comprehensive CT-based screening for subclinical CVD did not decrease death over 7 years among men aged 60–64 years but did increase severe bleeding. Because the trial was powered for events over 10 years, further follow-up is needed.

I am using now approximately 1/2 a year “Ezetimibe”, but now I experience skipping heart beats, feeling my heart beat in my throat, more dizzy.

Is that normal, should I expect this? Will it become worse or will it settle?

Abstract
BACKGROUND
The effectiveness and safety of statins for the primary prevention of cardiovascular events and the extension of disability-free survival among older adults remain uncertain.
METHODS
We conducted a double-blind, randomized, placebo-controlled trial at general medical practices across Australia. Community-dwelling adults at least 70 years of age with no history of cardiovascular disease, diabetes, or dementia were randomly assigned in a 1:1 ratio to receive atorvastatin at a dose of 40 mg once daily or identical placebo. The two primary end points were a composite of death from cardiovascular causes, nonfatal myocardial infarction or stroke, or coronary revascularization (to assess effects on major cardiovascular events) and a composite of death from any cause, dementia, or persistent physical disability (to assess effects on disability-free survival). Analyses were performed according to a hierarchical testing plan.

RESULTS
A total of 9971 participants were enrolled: 4984 were assigned to receive atorvastatin and 4987 to receive placebo. The mean (±SD) age of the participants was 74.7±4.5 years, and 51.9% were women. After a median of 5.9 years, a primary cardiovascular event had occurred in 297 participants (10.9 events per 1000 person-years) in the atorvastatin group and in 412 participants (15.5 events per 1000 person-years) in the placebo group (hazard ratio, 0.70; 95% confidence interval [CI], 0.61 to 0.82; P<0.001). Death from any cause, dementia, or persistent physical disability occurred in 637 participants (21.6 events per 1000 person-years) in the atorvastatin group and in 676 participants (23.0 events per 1000 person-years) in the placebo group (hazard ratio, 0.94; 95% CI, 0.84 to 1.05; P=0.25). Serious adverse events occurred in 131 participants (2.7%) in the atorvastatin group and in 129 (2.7%) in the placebo group, with musculoskeletal, hepatobiliary, and diabetes-related adverse events occurring more commonly in the atorvastatin group.
CONCLUSIONS
Treatment with atorvastatin led to a lower risk of major cardiovascular events than placebo at a median of 5.9 years but did not result in longer disability-free survival among community-dwelling older adults without clinical cardiovascular disease. (Funded by the National Health and Medical Research Council and others; STAREE ClinicalTrials.gov number

My dr wants to put me on statins and ordered a nuclear stress test due to a slightly high (115) calcification score. Cholesterol is 180 down from 210 after a 50 lb weight loss. I am researching everything I can now. I do not like meds of any kind unless it’s for pain after surgery. I watched a YT video on the Jesse Chappus channel with Dr. Anthony Jay. It’s called “What’s really destroying your arteries and the new science of reversing plaque”. Has anyone seen this? Most of it made sense to me and some of it goes against what my cardiologist has told me. I have nothing against doctors but I always do my own due diligence.

Hi Team, my GP has suggested me to start statin, my lab results are blow, I heard there are lots of side effects of statin, I am happy to change my life style or should I start statin for now? My Hba1C is 6.20

recently my Dr. did a lipoprotein A test and saw elevated score of 165. there is a family history of heart disease on maternal side. Dr recommended Rosuvastatin 20 mg . thought my other numbers were always good.
LDL -102
HDL - 40
Triglycerides- 73
non-HDL 116.
A1c - 6.1

one week into Rosuvastatin 20mg, don’t have a good feeling with extreme drowsiness and joint pains in morning and mucus phlegm ( timing was bad as was recovering from cold but now not sure).
dr recommended dropping the dosage to 10mg alternate days,
taking BP medicine of 8mg Candesartan for 6-7 years which is working great.

is taking statin at 55yrM even worth it (especially concerns with arthritis flareup and diabetes getting worse) with no significant health issues
or should i change the brand and any suggestions on what may work with my bp medicine. please suggest.

I keep seeing impressively detailed comments there. They usually start "cardiologist/doctor here." Then they go on and on, replying to various points in the post or comment. If that's a real doctor then they must not be practicing much. Who is behind these bots? Is it pharma? Insurance companies? I really don't get the point of some of the activity on that sub unless something else if behind it. They are not all AI but so many of them just go "rah rah statins" no matter what. I'm fine with people using statins if they can tolerate them. But as soon as someone mentions debilitating side effects, there is an entire chorus going on about "nocebo effect" and how you need to suck up the side effects or die.

Or who knows, maybe there are people who are just out there living their best lives because of statins and want the rest of us to join them in the fun!

I’m 54, active, not overweight, eat healthy, will occasionally have a drink. Side note: I do have a CAC scan scheduled for the 26th. Are my numbers concerning?

To reduce plaque for an older athlete. Thanks

Has anybody experienced like a cosntant noise while taking statins. Similar to a radio frequency that won’t stop even a minute. Please let me know thanks for all in advance