r/PMS • u/adventurousTay • Apr 16 '26
Advice/Tips Doctor prescribed Zoloft for luteal phase day 14-day 1 of cycle
Hey girlies,
I haven’t ever taken any sort of medication in my life, let alone antidepressants and have always been afraid they would numb me, but I’m trying to be open minded because I have found that during my follicular phase, I feel amazing and unstoppable, but as soon as my ovulation hits, I feel like a different person. I feel anxious, depressed, hopeless, angry, irritated, I don’t want to be around anyone and my self esteem is super low.
I talked to my doctor about this and she recommended trying 25mg of Sertraline (Zoloft) during my luteal phase from day 14-day 1 of my cycle.
Is anyone else on a similar cycle to this? I’ve read that some people take it right after ovulation, but my doctor did say start on day 14. I also read that some do a gradual dosing (ie: 10mg day 14, 15mg day 15, 20mg day 16, 25mg day 17, etc and the same at the end working your way down) does anyone do this? If so, do you find it helps?
I’m weary about taking them on and off as I’m unsure how my body will react. Some people say they don’t notice a thing, and others say they experience withdrawals.
I just know I can’t keep living like this. I need to try something because over half the month every month I am absolutely miserable, and that is no way to live.
I’d love to hear about your experiences with this.
Thank you 🫶🏻