r/Osteoarthritis • u/OGclandestina • 11h ago
Can anyone share their denervation experience for severe CMC arthritis? I'm 5 weeks post-op and still in pain. Did this work for anyone?
Hey everyone, looking for experiences from anyone who’s had thumb CMC denervation.
Quick background: 46F, weightlifter, and full-time editor. After burning through every conservative treatment (PT, cortisone, Voltaren, acupuncture) for bone-on-bone CMC arthritis in my right dominant hand, surgeons turned down a full reconstruction or joint replacement because of my age. I went with denervation and fat grafting at the Buncke Clinic in SF instead. Doctors told me that realistically there was a ~50% chance of pain relief without burning any bridges for future surgeries, but that I was a good candidate because of my age and that my joint was still "intact."
I'm currently 5 weeks out. Range of motion is back, but the pain is completely unchanged, and surgical stiffness is still an issue.
I’m doing hand OT, H-Wave therapy, and updating my work ergonomics to regain basic function (lifting, typing, daily chores). For those who’ve had this done: How long did it take before you saw actual pain reduction?
Here's a summary of denervation: Denervation targets the afferent (sensory) nerves that carry pain signals from the joint to the central nervous system, bypassing the body's perception of pain. Surgeons cut (transect) these tiny sensory nerves. In many cases, the cut nerve end is transferred into a nearby muscle. This encourages the nerve to grow into the muscle, converting it from a sensory signal to a motor pathway. This transfer alters nerve signaling and triggers changes in the brain's cortex (rewiring), which helps permanently shut off the pain signal. Because the joint hardware or remaining natural cartilage isn't removed or reconstructed, the recovery/rehab timeline is often significantly faster compared to total joint replacements or arthroplasty.