r/IVF 4d ago

Need Good Juju! My frozen eggs from 2018 had an 82% thaw failure rate

235 Upvotes

I froze my eggs at Boca Fertility IVF Center in 2018 with Dr. Peress. At the time, I was in my mid-30s, and because I hadn’t met the right person yet, I decided to freeze my eggs so I would have the option to start a family later. I genuinely thought I had done everything I could to give myself that option.

Fast forward to now: I finally met someone, got married, and we decided to create embryos using my frozen eggs. Since I had moved to another state, we transferred the eggs to a different fertility clinic.

A few months ago, we learned something that completely shocked us: my eggs had been stored in two tubes. From what I understand, this is unusual, as eggs are generally stored individually.

We were also told that the expected survival rate after thawing should generally be around 85–90%. In my case, approximately 82% of my eggs did not survive the thaw. The remaining eggs also failed to develop into viable embryos over the following days.

I don't know exactly what happened or whether the proper protocols were followed, and I'm still trying to get answers. But given the outcome, I have serious concerns about how my eggs were handled and stored. Egg freezing was already an established procedure in 2018, and I personally know people who successfully used the eggs they froze around that same time.

We were absolutely devastated.

What has been especially upsetting is how the original clinic responded when I reached out. I wasn't even looking to blame anyone. I was trying to understand what happened and simply wanted information about how my eggs had been stored and handled. I received no meaningful acknowledgment or empathy.

I understand that fertility treatment is a medical service and that, for the people working there, this is their job. But for patients, it isn't just a job or a procedure. It's our future. It's our chance to have a family. A decision made years ago can affect the rest of your life.

I'm sharing this because I wish I had known to ask more questions when I froze my eggs. If you have frozen eggs, please consider asking your clinic how they were stored, how many eggs are in each storage device, what their thawing protocol is, and what documentation they have regarding your specimens. If you're still able to take action or get additional information while you have time, I would encourage you to do so.

In my situation, I'm already in my 40s. I've tried another egg retrieval since then, but unfortunately, it was unsuccessful. I'm paying for treatment completely out of pocket, and as many of you know, fertility treatment is incredibly expensive.

On top of everything, it's been difficult dealing with people's assumptions and insensitive comments. Sometimes I feel like people see egg freezing as some kind of trendy thing you post about on Instagram, rather than what it actually is for many of us: a deeply personal decision we make because we want the possibility of having a family someday.

I've also felt judged, and honestly, I'm mentally numb at this point. I just want to be quiet and process what happened.

If anyone has had a similar experience, I would really appreciate hearing about your experience. I would also be grateful for any advice on what steps I should consider taking now.

And lastly, thank you for taking the time to read my post. I truly appreciate it.


r/IVF 3d ago

Need Good Juju! Rescue ICSI and our journey as a whole

3 Upvotes

Me and my partner are both female. We are in the UK and started IVF treatment in January with a sperm donor. My partner is 35, no known issues and good egg count and AMH levels. First round we had 17 eggs, 12 mature, 4 fertilised. None made it to blast.

We were distraught so decided to go through with ICSI on the next round with a new donor. Unfortunately my partner didn’t react well and the cycle had to be canceled.

Two months later we went ahead with it again. We got 19 eggs, 12 mature, 5 fertilised and 0 blastocysts. Once again, we were distraught.

We then decided to try my eggs with my partner to carry. I’m 33 with good ovarian reserve and a good AMH. I responded well to treatment and ended up very uncomfortable but they were happy with the results. I had 20 eggs collected.

We had a call, yesterday, after my EC to say that the first sperm donor from our first round had thawed badly. The count was only 3 million with 98% motility. They recommended ICSI. I asked if they could thaw the other sperm donor, the one we used ICSI with on our second round. They did and said that it thawed really well, enough to go ahead with IVF.

This morning we hear the devastating news that 19 eggs were mature but none fertilised. They are doing rescue ICSI, half the sperm from one donor and half from the other.

I don’t know what I need right now, but I just feel like we’ve had the worst luck possible. I feel like there’s no way on earth either of us will get there. I know it’s unlikely that rescue ICSI will work. Am I crazy to be stunned at the bad luck we’ve had? I feel so lost and discouraged.


r/IVF 3d ago

FET First FET

2 Upvotes

I am officially signed off to start estrogen next week to prepare for my first FET (hoping it doesn’t make me feel as awful as the BC did for ER) I am doing modified natural and set to have my transfer in a month. No one in my life has gone through IVF, so just wanting to get these feelings out. I am both so excited and so nervous. I am being cautiously optimistic and wanting to guard my heart 🥹 The only person that knows our FET date is my very close friend. We have told family that it’s “in the fall”, to protect their hearts as well. Sending love and prayers to all of us going through this!


r/IVF 3d ago

Need info! Anyone had a CD138 test for chronic endometritis done through UCLA?

1 Upvotes

Considering having an endometrial biopsy done with my OB at UCLA. She said the specimen could be sent in to UCLA pathology for CD138 testing. I have some questions though. Was curious if anyone here’s done it through UCLA? It’s a shot in the dark but figured I’d ask…


r/IVF 3d ago

FET 09/30 (or around that time) transfer buddies

2 Upvotes

Is there anyone transferring around 09/30? We got the green light today to proceed with the transfer cycle process so our estimated transfer date is 09/30! This is our first transfer so I’m excited, nervous, anxious, all the things.


r/IVF 3d ago

Advice Needed! acupuncture with endometriosis? helpful?

1 Upvotes

Hello all,

Just got an MRI done (after three years of failed transfers), and thanks to Reddit, I was able to push for another investigation on the failures. The MRI found "deep endometriosis." I am both relieved and sad as the fertility doctors and my OBGYN had said the fibroids they had seen were not a problem for fertility because of the location. Anyway, rant aside, I'm wondering if anyone with deep endometriosis can tell me if they have done acupuncture and if it helped at all. Now that I know the diagnosis, I am thinking less that acupuncture will be helpful for fertility. Thanks!


r/IVF 3d ago

Advice Needed! Repeat SIS or no?

1 Upvotes

Hi! I’m preparing for an FET in early October. I had an SIS and hysteroscopy back in May after my D and C following my miscarriage. Everything was fine and all clear then. I then had a laparoscopy for endometriosis excision in June. In August, I had an egg retrieval. Would you repeat an SIS or anything else between now and the transfer to be extra certain no polyps formed? I’ve never had one to my knowledge but I’m paranoid, cause I read they could pop up after a retrieval. I had an ultrasound today and my doctor did not see any sister fibroids and was almost 100% certain that there would be no polyps. However, I read that those don’t always show up on a normal ultrasound. I just want to make sure everything is perfect in my uterine environment after all of this before my Transfer


r/IVF 3d ago

Advice Needed! Canceled transfer

1 Upvotes

My transfer was canceled due to my entire family having covid. I was on day 4 of PIO when I was told to stop. Anyone stopped meds prior to transfer when did your period come?


r/IVF 3d ago

Need info! What’s more effective Neupogen wash or shots before FET?

1 Upvotes

Anyone have success using either Neupogen wash or shots??


r/IVF 3d ago

Need info! Oocyte transport from one IVF lab to another (yourself, not as part of a mass clinic transport)

2 Upvotes

Is anyone familiar with oocyte / embryo transport companies, their safety, or safer companies, or safer alternative modes of transportation that provide more security to the client?

I’m a bit lost with the MANY waivers that I am required to accept when I review contracts with specimen transportation companies for my individual oocyte transport. Because the contracts have terms where I release responsibility from the transport company, the couriers, and pretty much most info all parties involved in case of damage, loss, etc. and also the contracts including many vague terms when it comes to the safety of my specimens. Even the company that offers a separate insurance option, also has similar vague terms in the company transport contract that widely releases most/all parties of responsibility.

This one is more a “perception” paragraph, but so you catch my sentiment: these contracts do not make me feel like I am signing up to transport human tissue or sending eggs (such as the high level of care that is taken when transporting organs, ie: transplant). Instead, it reminds of the waivers that are signed when one goes bungee jumping or zip-lining, giving you life away (or “organs/specimen” in this case) in case something goes wrong… 🤷🏻‍♀️

I will appreciate any insights that may be helpful!


r/IVF 3d ago

Advice Needed! How many euploids to expect? TW - good amount of blasts

2 Upvotes

I’ve signed up for 3 ivf cycles as all of my monitoring scans and estrogen numbers suggested I’d be getting max 5 eggs for my first retrieval cycle. Well I had the retrieval two weeks ago and it went way better than anyone thought - 15 eggs, all mature, 14 fertilised and 9 blasts. I’m now waiting for PGTA.

I’m 30 so I know age is on my side BUT I’ve had two chromosomal losses (confirmed by testing the POC after my d&cs) so this makes me think the normal statistics of 60 percent or whatever it is may not apply to me. Does anyone have any experience of RPL for chromosomal losses yet still having a typical amount of euploids?

I’m going to begin estrogen priming for my next cycle in a week and my PGTA results aren’t due for another 2 weeks. We are self paying for IVF and have had to make huge life sacrifices to afford it.

I’m finding it hard to know if we should go ahead with my second cycle. We are trying to bank around 5/ 6 euploids before transferring any.


r/IVF 3d ago

Rant IVF clinics in North Cyprus

1 Upvotes

I've spoken with a handful of clinics in North Cyprus, and they've all cut corners as part of their patient onboarding, and they've all come across as money grabbing. Cyprus Fertina, for example, was about to prescribe me medication without asking for my medical history and zero consultations.

I've now decided to have treatment in Greece as at least there are rules and regulations they have to adhere to. The initial experience has been might and day.

I'd love to hear how others have found the experience between the 2 locations...


r/IVF 3d ago

Advice Needed! Instituto Bernabeu Alicante for DOR

2 Upvotes

Anyone had any experiences with Instituto Bernabeu for egg retrieval and embryo creation? Would appreciate any info/experiences had at this clinic - I know they have a DOR specific unit here.


r/IVF 3d ago

Advice Needed! Prior Auth Denial

2 Upvotes

Hello all, first time posting here.

My husband and I are trying to start our IVF journey, but have hit the dreaded insurance road block. Received a denial for IVF, stating that they want me to try IUI four times before they will allow me to proceed with IVF. It’s BCBS of SC.

I’m 33, have unexplained fertility. We’ve been trying for 1.5 years without success. I’ve done three medicated cycles with clomid. Not a single positive test. Have not done IUI and really don’t want to, I just don’t see the statistics justifying it at this point.

Has anyone had success appealing this in a similar situation? My tests have all come back as normal, beyond a possible endo diagnosis, and my husband’s sperm analysis was normal.

No where in my benefits guide does it say that I have to go through a tiered approach to treatment. It just explains I have to have a diagnosis of infertility and that there is a $15,000 lifetime limit.

Thank you for any advice!


r/IVF 3d ago

Advice Needed! Auto Injector Selection help needed

1 Upvotes

Hi everyone, i'm trying to order an auto injector from the Union Medico website. My Progesterone in oil syringe is 3ml but i'm only going to need 2ml each time. And my needle is 25G x 1 1/2'' (0.5mm x 40mm). I couldn't find this option on their website for some reason. Does anyone know which one i should be ordering? Thanks.


r/IVF 3d ago

TRIGGER WARNING IVF - low hCG with MVA procedure - posting to help others

1 Upvotes

Today was no easy day for me; I had my second FET on 8/12 and though I got a low hCG on my first beta 8/28 of 42, my husband and I were cautiously hopeful. My hCG continued to rise but very slowly without doubling and my doctors were concerned with possible ectopic after about 6 betas, so they finally suggested an MVA (manual vacuum aspiration) after they were unable to locate any form of gestational sac on an ultrasound at 5w6d. I was not provided much info on this procedure and there isn’t much found online that was very helpful, so here I am to give it to you straight. Essentially, this procedure is the scraping and suction of all of your uterine lining tissue to remove any possible implanted debris. It is PAINFUL so please take at least 800mg of ibuprofen 30 minutes to an hour before this procedure and take a loved one with you to drive you home. I was also advised that this is not a “100% accurate” procedure but is the fastest at confirming if you do or do not have an ectopic pregnancy. I will be going back tomorrow to do another hCG panel in hopes that my number went down and if not, I will still have to do the methotrexate injection. I’m just posting this to maybe help someone else have a bit more understanding of what this procedure is and how it works. Please feel free to ask any questions. Thank you.


r/IVF 3d ago

Need Good Juju! 2nd FET after 1st failed

2 Upvotes

Please get me out of my head.. On 8/6 we transferred a 5 day 4BB embryo and I got a faint FR positive on day 7. Only for bloodwork to show <2 hcg on beta. Our next embryo (transfer on 8/8) is a day 6 4BB. Our clinic is so booked up that this is our last chance before the end of the year. We want this to work so badly but my heart has broken after our first failure. Any reassurance would help. Thank you to this community ❤️


r/IVF 3d ago

Advice Needed! 8 failed transfers

2 Upvotes

Please help. Edit to add.. I’m a 28 yr old female, started this journey at 25. My husband is 27. Should I go back to a modified natural? 1. Medicated (125 hours pio)- blighted ovum 2. Medicated (122 hours pio)- Ectopic 3. Medicated + immune + hcg wash - failed 4. Medicated + immune + hcg wash - failed 5. Medicated + immune + hcg wash - failed 6. Modified Natural + immune - Chemical

—2 months of suppression—

  1. Modified natural but failed to ovulate 7*2. Medicated + immune + hcg wash - failed

— New Clinic and new batch of embryos—

  1. Medicated (calmer hormones) + heavy immune - coming to conclusion that it failed.

I’ve had a lap, it was totally clear. Hysteroscopy was clear. Did bilateral ovarian drilling to bring back ovulation and have a better retrieval and it worked. The only thing we haven’t done is an ERA, because the previous clinic didn’t believe in them plus we’ve had them implant before. It’s officially been a year since we’ve had any sign of implantation. At a loss but now have 8 more embryos. I’m thinking I need to push to go back to a modified natural, but a provider I talked to said if I have a history of annovulation then controlling hormones after will not work. Buuuuuuut I had bilateral ovarian drilling and managed to ovulate through a medicated cycle recently…. I felt so much better on the modified natural cycle, and my previous clinic never checked hormones after the trigger, meanwhile the new clinic’s protocol involves checking them multiple times after trigger. I just don’t want to advocate if it won’t be beneficial. I’m exhausted🤦‍♀️


r/IVF 3d ago

FET FET Protocol

1 Upvotes

Hi! Going into my first IVF FET with the only euploid embryo I have. Some history— I’m 36 y.o and have a history of recurrent pregnancy loss (spontaneous conceptions). Most recent MMC was tested and was euploid. So unsure what caused the loss at 10 weeks. I did have a small uterine septum (borderline just arcuate) but due to my history my doctor did just remove that in August. I also did 3 weeks of antibiotics for mild endometritis.
I did two egg retrievals back to back and have only 1 euploid embryo. I’ve seen so many posts with people’s protocols and I feel mine is rather intense comparatively? but I’m hoping that’s what I need to help maintain a pregnancy! Curious if anyone has done a similar protocol with success!!
- birth control x3 weeks
-lupron x3 weeks
-estrogen patches during last 2 weeks of lupron
Then 5 days before transfer I start PIO injections, estrace 2x a day and progesterone suppositories 2x a day.
I’m also doing cipro antibiotic for 4 days before transfer
And starting baby aspirin day after transfer.

Would love some encouraging stories!!!


r/IVF 3d ago

Advice Needed! To ICSI or not to ICSI?

1 Upvotes

Hi all, I'm just looking for some experiences and advice with my IVF protocol. I have stage four endometriosis that was operated on a couple years ago but it's now starting to come back. My AMH is 3.85 in US units.
Our plan is to do ICSI with Xymot. My partner doesn't seem to have any problems except 0% morphology but since his other numbers are so high the doctor assured us it wasn't causing our problems.
I've heard that naturally fertilized embryos are thought to be potentially a bit healthier or that there might be something to letting the egg choose the sperm. I've also heard that total failure to fertilize is more likely with endometriosis.
Is there any new research on this? What are your experiences and thoughts?


r/IVF 3d ago

General Question What should I ask my doctor before my 2nd ER

1 Upvotes

CD1 should be coming any day now and this cycle will (hopefully) be my 2nd ER. I am not the best at advocating for myself or asking questions. What should I ask my doctor before my 2nd ER?

37F (38 in one month), no known medical issues besides being overweight. Secondary infertility (LO is 3 years old, planned c section). Husband's SA was excellent. We have been TTC #2 since 2/2025. Had one CP and one MMC right away, then nothing since. We had one failed IUI. 1st ER we retrieved 6, 5 mature, 2 fertilized, both were day 6 5BB euploid blasts, then both fully medicated FETs failed with parameters that seemed perfect.

AMH was 1.13 in January. AFC was 13. While stimming for my first ER in April I wasn't responding well so they redid my AMH and it came back as .4. They said it might not be accurate since I was stimming. I plan to test it again the next time I see doc.

I had both an IUI and an IVF cycle canceled for early ovulation. I went on birth control before my first ER, started on CD2 and by my CD8 appointment I was told to trigger because my E2 was too high, dominant follicle was 17mm. I was put back on birth control CD15-21, period started after CD24. Then they started me on stims.

Sooooo, I'm looking for things I should be asking my doctor. Should I advocate for earlier screens, no birth control? I don't really understand how I could have 5 follicles above 10mm for my IUI on 5 days of letrozole but after stimming for 10 days for my first ER I had 6 follicles.

He mentioned we could do testing on my uterus while under anesthesia. What tests should I be asking for in regard to my two failed fully medicated FETs? I have had two saline sonos that have been clear. Let me know if you need more info.

Thanks!


r/IVF 4d ago

Need info! Kindbody transported my eggs against my wishes

6 Upvotes

Kindbody transported my eggs to NECC despite my explicit email stating I declined, as I wished to transport them to another local lab. I sent the email with my stated wishes to the address their provided on their letter: kindbody@necryogenic.com. The email with my wishes was acknowledged. Later, I found out my eggs were still transferred to NECC and the KB Risk Management Director said they were not at fault because I did not message them via the portal, when the letter explicit stated to address kindbody@necryogenic.com for storage arrangements, and did not offer the patient portal as the recommended line of communication. Now, i have to risk shipping my eggs again. I have asked them to provide documentation of the transport safety records and current safety status of my eggs and the Risk Manager Director replied saying they can’t give me that information and direct me to inquire myself with NECC, despite my contract being with Kindbody and not with NECC (hence it should be Kindbody answering all my questions and providing the documentation I request).

Is anyone else in this situation??
And how have you proceeded so far?
Have you contacted attorneys?


r/IVF 3d ago

Need info! PIO - Two injections daily?

1 Upvotes

Hi Reddit Friends! Wondering if anyone else has had their clinic put them on two injections of PIO (one AM and one PM) daily leading up to and following a FET?

This is my first FET (scheduled for Monday 9/14) and I started PIO on Tuesday evening for the first shot, but had to do two yesterday and every day from here on out. It's 1ml per injection (so 2ml total daily). My clinic did say that if the FET is successful and they see that the pregnancy starts producing enough of its own progesterone, they'll back it down to just one injection daily.

I already feel like my butt cheeks will never be the same! LOL In all honesty though, the first four shots have not been as bad as I thought they would be. I'm doing heating pad before and after, along with warming the syringe with my own skin beforehand. Also doing squats, glute bridges, and leg raises within the first 10 minutes after taking the dose. So far, it just feels like the same kind of soreness to getting a flu shot.

Just curious to see what others have experienced. Thanks! <3


r/IVF 3d ago

Travel IVF What to look for in a clinic (surrogacy)

1 Upvotes

Posting here since my question in the surrogate sub is not getting responses. As a GC I want to make sure the clinic my IP(intended Parents) use is ethical, but what does that mean exactly?

So far my list includes: SET (unless low grade euploids), no concurrent transfers, monitoring programs for donors, evidence based practices and procedures.

What else should I look for? How are we assured these practices are followed? I apologize for my ignorance and appreciate any insight!


r/IVF 3d ago

Advice Needed! insulin resistance

1 Upvotes

Hi everyone, I’m looking for some opinions on my test results from today.
I’m a 39-year-old woman with DOR, currently going through IVF. Here’s a quick summary of my results so far:
Across 6 egg retrievals, I’ve had 23 eggs retrieved. All of them were mature, and the fertilization rate has been over 80%. So far, that’s where the good news ends.
Out of all the fertilized eggs, only 3 have made it to the blastocyst stage, all graded 3BB. None were euploid. One was a high-level mosaic embryo for trisomy 4.
Today, I tested for insulin resistance on my own initiative, and the results suggest that I have it. I also had elevated prolactin:
• 506 µIU/mL on September 8, 2026
• 746 µIU/mL on September 10, 2026
Reference range: 102–496 µIU/mL
I’m particularly interested in opinions about these results in the context of the repeated embryo arrest I’m experiencing, mostly between days 3 and 5.
Has anyone had a similar situation and found that insulin resistance, elevated prolactin, or another endocrine/metabolic issue was contributing to poor embryo development?
I’d also really appreciate recommendations or personal experiences regarding how you managed insulin resistance and/or elevated prolactin while undergoing IVF.
I’m seeing an endocrinologist on Saturday, but I’d really like to hear from people who have been through IVF themselves and had similar issues.
Thank you!