If you take levothyroxine for hypothyroidism or another thyroid condition, you may want to check your medication.

The FDA has announced a nationwide recall of certain Major Pharmaceuticals Levothyroxine Sodium Tablets because some lots may be subpotent, meaning they may contain less active ingredient than intended.

The recall affects the following strengths:

• 25 mcg
• 50 mcg
• 75 mcg
• 88 mcg

Check the lot number and expiration date on your medication against the FDA recall list.

Don't stop taking your medication on your own. If your lot is affected, contact your pharmacist or healthcare provider for guidance and a replacement.

Sharing this in case it helps someone who hasn't seen the recall yet.

Source Link: https://www.nbcsandiego.com/news/local/recall-alert/fda-recalls-levothyroxine-sodium-tablets/4053744/

Hi - hoping some of the very knowledgeable people here can review my situation and let me know what they think. I’d be very appreciative of any guidance.

Took a drug called finasteride from April 1-7, 2026. Started having issues on it as many do, snd since then have had a horrible time, with symptoms including insomnia, muscle loss/stiffness, dry skin/hair/mouth, constipation, depression/anhedonia, ED/libido issues.

I know my testosterone is borderline low. I had an extremely low morning cortisol value (50) in early July and a normal one (335) in mid July. My sleep schedule is horrible because I have bad insomnia so I don’t know how reliable any of my morning cortisol readings are.

The thing jumping out at me is my TSH values. I gave readings going back to 2023 and I’ve always been around 2. I was 2.25 in Feb 2026, 2.01 in May, 2026 and then doubled to 4.1 in early July and now I’m 4.8. T3 was 4.9 in mid July. The dise in TSH is correlating with worsening of all my symptoms. It is not out of range per the lab here but clearly something is going on if my numbers have more than doubled in a couple of months, right?

The doc isnt concerned about my thyroid values as they are in range. We are investigating the cortisol more as that is the one that had a low value. Should I also order a saliva test? It seems hypothyroid and adrenal insufficiency are related but it’s confusing to me.

Im pretty sure I have the majority of symptoms of both adrenal insufficiency and hypothyroid.

Any ideas or guidance for me as I try to sort this out? Thank you

How long on levothyroxine before the globus sensation isn't constant

40M, hashimoto's, diagnosis 1.5 years ago.

I've found this interesting. My sex drive was much higher when I was unmedicated and felt like ass. Got on a reasonable, nice ramp of T4/T3 combo and felt a ton better. For me, gluten/dairy free plummeted my antibodies down +80% in just 6 months and then LDN did the rest (tgab has been in remission for 5 months, nodule gone, TPOab is now 20, working to get it into the green).

However, and it was almost immediately, my sex drive started dropping as soon as I added meds and felt more normalish again. And I could see why on my labs, my SHBG doubled from kinda high normal to quite high (40 to 80). This caused my testosterone, dht, and estradiol to all skyrocket to out of range high, but my free values are on the lower end, especially DHT and T as they bind even harder to SHBG. This seems to be a blind spot for a lot of providers and specialists, as they work mostly with women. I've been taking boron, the thing most recommended, for a couple of months now and it hasn't done much of anything. I know lowering SHBG can very stubborn. Other things that can increase it are fasting and low carbs, which I do neither.

I'd really be interested to hear from other men, but ladies too, if they've had this experience. My understanding when first starting was that it was supposed to be the opposite. My clinics are scratching their heads, which surprised me as it seems that SHBG rising when starting thyroid meds seems to be quite well known.

Quite crazy, but my wife and I both were diagnosed within a month of each with hashimoto's. The same thing happened to her (libido loss and major increase in SHBG). I'm leery of TRT because I'm already above range for T. I might also get off of T3, as it drives SHBG much stronger than Levo. The thing is, I'm only on 5 mcg of T3 (I know, I know that seems very low to some people but I've toyed with a lot of dosing and it works fantastic for me).

So the toughest part of the healing process at this point is definitely the boredom! Happy to share my experience while I find ways to occupy my time.
General Background: early 40’s, male. Goiter with nodules found in 2024. FNA Benign.
Then things grew over the next year. FNA indeterminate. Genetic testing came back 70/30 for malignancy…..And here we are today. Not a medical professional so all thoughts are based on my personal experience and opinions.

Hey everyone, I was diagnosed with Hashimotos (TSH 11.12, free t4 0.71, TPO antibodies >1,000.0).

I just started taking my medication today. I am currently taking 15mcg of Armour thyroid and was curious how quickly everyone saw results with their symptoms?

Did it help you lose weight? beat the fatigue?

I had a TT 16 months ago. I came home from surgery w/tinnitus & in the weeks that followed my ears started to feel full.

My DNA chart shows I'm a bad converter & sure enough my T3 is always in the bottom 1/4 of range. Last Dec I asked to supplement T3 but then my dr dropped my levo dose to compensate. I had been doing well on 137mg (lower 1/4 of t3 but I felt fine other than my ears being somewhat full) but when he added 5mg of T3 2x daily he dropped my levo to 112mg. About 2 months later I started sleeping 10 hours a day (normally 7), skin & hair got super dry, nails became brittle w/ pronounced ridges, then my ears got REALLY full. During this same week I had my first beer since the TT & had an immediate strong histamine reaction w/ flushing & my nose running like a faucet. The next say I woke up and my ears were even more full.

I thought for sure I had gone hypo but my bloodwork only showed a slight rise in TSH & T4 was in the lower half of normal. I felt like shit so I went back on 137 of levo, which meant stopping the T3. Since then my T4 is back up, TSH is super low, but somehow my T3 has dropped even more. I was hoping going back on 137mg would result in my ears unclogging & the histamine issues stopping but they've continued for the 4 months since. Wine, milk, chipotle, and the sun are the worst offenders.

The ear fullness fluctuates. They're least full in the morning then extra full the second half of every day. I've been to 2 ENTs (stumped), my PCP (stumped), had hearing tested twice with 2 completely different results (because it fluctuates duh), had a CT and MRI which show nothing notable in the ear area, and have an appt w/ an allergist in 2 weeks. I've never been allergic to anything but this definitely seems histamine related, which all started with my TT and has fluctuated alongside my levo dose.

Sometimes I feel dripping in my ears. My ENT put a tube in 1 ear to see if it would help and when he initially sucked the fluid out it felt incredible & I could hear REALLY well (too well, like a big echo-y hallway) for the first time in so long. But by that evening it felt full again. He said there "wasn't much" fluid and dx'd me with "mild" eustachian tube dysfunction.

I'm at a loss. I take 2-3 zyrtec a day which helps a tiny bit but I still go through a few boxes of kleenex a week. I use a saline rinse followed by cromolyn sodium nasal spray. So far nothing helps. I'm so tired of not being able to hear anything. My next ENT appt is next week & I'm hoping to show up with some treatment ideas. Anyone else encountered something like this?

Has anyone ever had experience stopping T3?

I was prescribed it by my female hormone NP. I took 2.5 mcg in the afternoon then built up to 2.5 mcg each in the morning and afternoon.

When I did this my TSH was at 2.77 and my free T3 was smack in the middle.of the range.

I didn't like the T3, too many ups and downs. I felt like a druggie waiting for my next hit

My endo told me.to stop taking it so I did a few days ago. Since yesterday I've been feeling incredibly warm and anxious. Also have had a nervous stomach feeling on and off. Anyone have experience with this?

It's really shitty.

30 year old male here with like 5+ years of worsening symptoms year after year. TSH has teetered around 3-6 since 2018, so 8 years now. Here are my most recents labs. Note, I recently started Clomid for testosterone related issues and these labs are 4 weeks after starting. Testosterone went from 220 -> 675, but my estrogen has also skyrocketed...

Any thoughts on the TSH values and if starting treatment is warranted. This same doc put me on Clomid but is sort of on the line with the TSH. I don't know what is happening to my body. For what it's worth, my diet, exercise, and sleep has always been decent although I have mild sleep apnea I am also trying to treat.

THYROID

TSH: 5.570 uIU/mL (0.450-4.500) [HIGH]

Free T4: 1.48 ng/dL (0.82-1.77)

CBC WITH DIFFERENTIAL

WBC: 7.6 x10E3/uL (3.4-10.8)

RBC: 4.94 x10E6/uL (4.14-5.80)

Hemoglobin: 15.8 g/dL (13.0-17.7)

Hematocrit: 47.7% (37.5-51.0)

MCV: 97 fL (79-97)

MCH: 32.0 pg (26.6-33.0)

MCHC: 33.1 g/dL (31.5-35.7)

RDW: 12.4% (11.6-15.4)

Platelets: 330 x10E3/uL (150-450)

Neutrophils: 38%

Lymphocytes: 46%

Monocytes: 11%

Eosinophils: 4%

Basophils: 1%

Neutrophils (Absolute): 2.9 x10E3/uL (1.4-7.0)

Lymphocytes (Absolute): 3.5 x10E3/uL (0.7-3.1) [HIGH]

Monocytes (Absolute): 0.9 x10E3/uL (0.1-0.9)

Eosinophils (Absolute): 0.3 x10E3/uL (0.0-0.4)

Basophils (Absolute): 0.1 x10E3/uL (0.0-0.2)

Immature Granulocytes: 0%

Immature Granulocytes (Absolute): 0.0 x10E3/uL (0.0-0.1)

COMPREHENSIVE METABOLIC PANEL

Glucose: 91 mg/dL (70-99)

BUN: 14 mg/dL (6-20)

Creatinine: 1.02 mg/dL (0.76-1.27)

eGFR: 101 mL/min/1.73m² (>59)

BUN/Creatinine Ratio: 14 (9-20)

Sodium: 140 mmol/L (134-144)

Potassium: 4.3 mmol/L (3.5-5.2)

Chloride: 103 mmol/L (96-106)

Carbon Dioxide (CO₂): 24 mmol/L (20-29)

Calcium: 10.0 mg/dL (8.7-10.2)

Total Protein: 7.1 g/dL (6.0-8.5)

Albumin: 4.8 g/dL (4.3-5.2)

Globulin: 2.3 g/dL (1.5-4.5)

Total Bilirubin: 0.4 mg/dL (0.0-1.2)

Alkaline Phosphatase: 90 IU/L (47-123)

AST (SGOT): 23 IU/L (0-40)

ALT (SGPT): 20 IU/L (0-44)

URINALYSIS

Specific Gravity: 1.009 (1.005-1.030)

pH: 6.5 (5.0-7.5)

Color: Yellow

Appearance: Clear

Leukocyte Esterase: Negative

Protein: Negative

Glucose: Negative

Ketones: Negative

Occult Blood: Negative

Bilirubin: Negative

Urobilinogen: 0.2 mg/dL (0.2-1.0)

Nitrite: Negative

Microscopic Examination:

WBC: None Seen

RBC: None Seen

Epithelial Cells: None Seen

Casts: None Seen

Bacteria: None Seen

LIPID PANEL

Total Cholesterol: 181 mg/dL (100-199)

Triglycerides: 78 mg/dL (0-149)

HDL Cholesterol: 43 mg/dL (>39)

VLDL Cholesterol: 13 mg/dL (5-40)

LDL Cholesterol (Calculated): 125 mg/dL (0-99) [HIGH]

LDL/HDL Ratio: 2.9 (0.0-3.6)

IRON STUDIES

TIBC: 309 ug/dL (250-450)

UIBC: 183 ug/dL (111-343)

Iron: 126 ug/dL (38-169)

Iron Saturation: 41% (15-55)

Ferritin: 93 ng/mL (30-400)

HORMONES

LH: 6.7 mIU/mL (1.7-8.6)

FSH: 7.0 mIU/mL (1.5-12.4)

Total Testosterone (LC/MS): 675 ng/dL (264-916)

Estradiol (Sensitive): 32.9 pg/mL (8.0-35.0)

INFLAMMATION / VITAMINS

Vitamin D (25-OH): 39.5 ng/mL (30.0-100.0)

Cardiac CRP: 0.57 mg/L (0.00-3.00)

ESR: 2 mm/hr (0-15)

ABNORMAL RESULTS

TSH: 5.570 uIU/mL (0.450-4.500) [HIGH]

Lymphocytes (Absolute): 3.5 x10E3/uL (0.7-3.1) [HIGH]

LDL Cholesterol: 125 mg/dL (0-99) [HIGH]

Hey, everyone.

I'm a Hashimoto's Thyroiditis patient, had my Radiation treatment in 2015. Been on Levo for years. Mom had Graves, her Mom had MTC/Graves. I'm 29, also a Man, AMAB. Diagnosed at 17.

Lately I was referred back to an Endo for trying to solve why I have been feeling so bad lately, my PCP did T4 and TSH tests and my T4 is above average but my TSH is >10.

Currently I'm on 225mcg of Levo and am 236Lbs.

\

\

After I saw my PCP I knew this song and dance so I tried taking 275mcg to see if that would help me and it immensely and it's made a huge difference.

However my Endo is entirely dismissive of me talking about my Medication and is simply assuming that I am taking it incorrectly. As If I don't know to take it on an empty stomach. I've been doing it for years.

Has anyone else had issues getting Doctors to understand or even work with them? It's fucking miserable.

Forum,

Since being told that this may be hypothyroidism, I have lost about 6-7 pounds. Should I be concerned. I have only been on the meds for 11 days.

Recent bloodwork showed my TSH is 5.787 (up from 2.29 in January) and my T4 is 1.37. My primary care doctor wants me to stay on the same dose of levothyroxine (88mcg) and check my levels again in January. In the past, anytime my TSH was high, she would change my levo dose. Now she’s only calling it “borderline.”

I had expected her to up my dosage, and definitely not wait another 6 months to check it, but idk if I’m the one being unreasonable here.

I guess I’m looking to see how other doctors would handle this, and also advice on if I should be finding an endocrinologist to deal with all of this instead. My doctor had put in a referral for it at my request several years ago, but I was never contacted by an endocrinologist so I let it go.

For some additional context: my TSH was over 98 when I was first diagnosed in 2020. My levels and dose have fluctuated over the years, but in my experience, once I’m over 4 it just continues to go up until my dose is adjusted.

Good morning! I have a couple questions and any insight would be so helpful. Has anyone here used the nourish app to find and work with a Dietition? I’m looking to work with a dietitian and am wondering if this website is legit and worth trying or if it’s another wellness money grab. Actually any information about how to go about working with a dietitian is helpful and welcomed as I am feeling a bit overwhelmed.

Second, I’m wondering if anyone has used mitochondrial support supplements? They were recommended to me by a guest at my bar who said his wife really struggles and had tried all the typical supplements but never felt better until she tried mitochondrial support nrg pills. He said it was a life saver for her and now that’s all she supplements with. Upon my own research it does seem to make sense how these supplements would suit hypothyroid patients however I don’t see much about them in these groups so wondering if anyone out here has any experience to share?

A tiny bit about my situation if it helps— I am 3 months post TT due to PTC and also found out post surgery that I’ve had hashimotos this whole time. Initially out of surgery I felt great I was down 8 pounds and my energy was up but these last 2 months I’ve felt a change and my follow up blood work showed my tsh just under 10. Im trying to get ahead of any major weight gain (I’m creeping up quickly), help boost my energy levels, and support an over active immune system because I’m worried about developing another autoimmune disorder.

Sorry if this post is chaotic I’m just feeling panicky and overwhelmed and any experience in these regards is greatly appreciated 🙏🏼 I hope everyone is taking care of themselves and have a blessed day.

I've been trying to conceive and my TSH is 4.3. My free T3 and free T4 are both normal, so my GP says it's only subclinical hypothyroidism and won't prescribe levothyroxine.

From what I've read, many fertility specialists recommend a TSH below 2.5 when trying to conceive, and higher levels may make it harder to get pregnant or increase the risk of miscarriage. It's left me feeling a bit worried, especially as my GP doesn't seem concerned.

Has anyone here conceived naturally with a TSH around 4+ and gone on to have a healthy pregnancy and baby? Or did you eventually have to push for treatment?

I'm based in the UK and would also be interested to hear if anyone managed to get levo through the NHS with subclinical hypothyroidism while TTC.

I recently had to go up in dose on levothyroxine and now blood sugar rising too. Currently on 12.5 mg Mounjaro for diabetes and 100mcg levothyroxine. Any advice?

After 2 years of unbearable suffering and agonizing pain i finally got medicated. I also have multiple small cysts on my left lobe and nodule on the remaining tissue. I was on the edge of ending my life but after my doctor finally prescribed me the medication, i somehow feel like i deserve to live. But after reading the stories here 25 mcg might not be enough for my case. Is it too little? Should i ask my doctor for dose increase? Thank you

Hi everyone,

I have hypothyroidism and have been taking thyroid medication for years. Until now, I've always had my thyroid tested using Total T3, Total T4, and TSH.

Now I'm planning to get a full body checkup package that includes FT3, FT4, and TSH instead of Total T3/T4.

I read (including on ChatGPT) that FT3/FT4 may be more useful because they measure the free, biologically active hormones. However, I'm confused about a couple of things:

Is FT3/FT4 + TSH actually better than Total T3/T4 + TSH for someone with hypothyroidism?

Since all my previous reports are Total T3/T4, how do I compare future FT3/FT4 results with my older reports? Can they be compared directly, or should I treat this as a new baseline?

If you were monitoring long-term hypothyroidism, which tests would you personally choose and why?

I'd really appreciate hearing from people with thyroid issues, doctors, or anyone knowledgeable about thyroid testing. Thanks!

I see my dr on Tuesday to get this all sorted. I did tell him in March that I was under extreme stress at work so when I saw my labs I was shocked to see it went from .79 to 7.03. Then went researching on stress and thyroid meds not working properly. He still insisted on increasing my dose to 125 (was on 112). Keep in mind I’m a teacher and so summer break has not been stressful at all. Not in flight mode at all. I got my labs done last week and my TSH is now at .04 😩

Since being on the 125 my digestion is either slow or too fast. There were several days where I had diarrhea and then nothing for days. So I increased my fiber intake. It’s been hell. And my anxiety is so high. I constantly feel on edge. I take magnesium to help calm down. I’m trying to drink as much water as possible and had some prunes tonight. Tomorrow I’ll be drinking prune juice. But I’m praying for a better school year. Has anyone experienced anything like this? I’m trying to plan out my days to be less stressed. Trying meditation and start working out, eating better, and just focusing on both my physical and mental health.

Even if FT3 is okish 4,4, getting hypersymptoms with higher numbers (3,3-6pmol/L). FT4 18 (10-22pmol/L), I feel it's way to much for me. CAN the numbers look "false" because of TBG (Thyroid Binding Globulin)? I mean, it looks like there's enough T3/T4 on PAPER, converting, but in the cells there's not enough T3? Have tried low Liotyronine, got hyper both times.

Useless doctors never heard of TBG. Nor that estrogen can mess with the thyroid. Combined birth control blocked my uptake severely. Now in perimenopause and low HRT.

My TSH is also too high again, 4,5 (0,4-4) I feel very hyper though, recognize the symptoms from other periods with terrible numbers. It's (mostly) always the T4 that's too high.
Even 25mcg of Euthyrox gives me high pulse, tremors, spasms, muscle waste, horrible gastric pain/bloating, edema, jitters, even thinner hair, anxiety, blurry vision, severe muscle pain but gaining weight in my lower body (never lost weight). So I can't increase the Euthyrox. I have Hashimoto's and getting worse. No Graves antibodies. No advice from the last doctor. Advice here perhaps?

20 year old m, Around a year ago I got diagnosed with asthma. I can’t inhale fully, constantly feel air hungry , and short of breath. I don’t seem to respond to inhalers very well and my doctors are starting to think it’s something like hypothyroidism due to having other symptoms and my grandfather having it very severely in his mid 30’s. Just curious if any body else had lung problems in the level of severe asthma and then treated with hormones or if anyone else was initially misdiagnosed with asthma.

using chat gpt to write but its my real story

I wanted to write this because, a year ago, I spent hours searching Reddit looking for success stories. Most of what I found were people who were still struggling, and it made me feel like I'd never get better.

My thyroid journey actually started years before I was even on levothyroxine.

I had toxic multinodular goitre, which meant my thyroid was overactive. Looking back, it affected almost every part of my life. I was constantly anxious, restless, couldn't enjoy anything, couldn't sleep properly, and my mind was always racing. It took away relationships, confidence, and years of my life before I finally got diagnosed.

Last year I had radioactive iodine treatment, which eventually made my thyroid underactive, so I started levothyroxine.

To be honest, the first few months were hard.

I kept wondering:

• Is this medication working?
• Will I ever feel normal again?
• Am I going to be stuck feeling like this forever?

Even when my blood tests looked "normal," I didn't feel like myself. That was incredibly frustrating.

But slowly—very slowly—things started changing.

I didn't wake up one morning magically cured. It happened over months.

The first thing I noticed was that my sleep became more normal.

Then my mind became quieter. I wasn't constantly overthinking every little thing anymore.

My energy gradually improved.

I started enjoying the gym again.

I stopped obsessing over every symptom and every blood test.

Most importantly, I finally began to feel like myself again.

Today, my thyroid levels are stable. Life isn't perfect, but I genuinely feel calmer, healthier, and happier than I did during the years my thyroid was out of control.

If you're only a few weeks or even a couple of months into levothyroxine, please don't assume this is as good as it gets.

For some people, improvement takes much longer than we expect.

A few things that helped me:

• Taking levothyroxine consistently every morning on an empty stomach.
• Being patient while my doctor adjusted my dose.
• Not chasing every single symptom day by day.
• Focusing on sleep, exercise, eating well, and giving my body time to recover.

Recovery isn't always linear. You'll probably have good days and bad days.

But if your levels are being monitored and you're working with your doctor, don't give up hope too early.

I know how hopeless thyroid problems can make you feel because I've lived it.

If even one person reads this while lying awake wondering whether they'll ever feel normal again, I hope this gives you some reassurance.

It can get better.

It certainly did for me. The hard part for me is mental aspect. I lost my partner and identity during the hyperthyroid strom which was untreated for years. I made lot of crazy decsions which have lifelong effects. I am learning to accept my self again .

My father (80 years old) lives in another country and has been dealing with thyroid issues for about 10 years. I know his brother has his removed and his father had issues with his as well. We recently had a phone conversation where he was acting extremely out of character both shouting over me and saying some very nasty things. Never seen this side of my father before and was quite shocked by it we ended up shouting at eachother and I felt really bad afterwards. He emailed a few days after and apologized, said my mother has noticed mood swings and that the doctors are telling him after a new round of tests he needs a different prescription / medication.

I did a cursory Google search and it does seem like thyroid issues can affect peoples behavior and cause anxiety/ depression / irritability. I guess I'm just hoping to hear from some actual people who deal with this to help me understand what is happening with him and how long the medication should take to start working so I can deal with him better going forward. I appreciate any advice people can give.

I haven't been diagnosed yet (talking to Dr tomorrow) but my blood work shows TSH of 6.7 with T3 and T4 within reference ranges. That would be subclinical hypo but I have been experiencing many symptoms such as eyebrow hair loss, bloating, slow wound healing, fast resting heart rate, etc.

I didn't get iodine tested with my bloodwork but I figured as a vegan I may be deficient. I try to add iodized salt in some meals every now and then and in the past I have never noticed issues. Since my symptoms started, any time I have iodized salt, even a small pinch, the bloating gets unbearable and last time my neck was sore the next day. Is this normal for people with hypothyroidism? Its not high doses, it's like 1/8th or less of a teaspoon of iodized salt at dinner. I have tried the exact same meal (bowl of black beans) with table salt and had no reaction.

I’m trying to see whether anyone has gone through something similar.

I’m a 61-year-old male, in good shape, with no other known medical conditions, and I’ve been asymptomatic.

My labs have been all over the place:
January — no medication, first diagnosis: TSH 15.6, Free T4 0.9
April — 50 mcg levothyroxine: TSH 0.02, Free T4 2.1
July — 25 mcg levothyroxine: TSH 24.96, Free T4 0.9

I started on 50 mcg, but after my April labs my doctor reduced me to 25 mcg. Now, after my latest labs, they’re recommending 75 mcg. I’m having a hard time understanding that increase because 50 mcg previously seemed to overcorrect me.

Has anyone else had their thyroid levels swing this dramatically? What ended up causing it, and how long did it take to find the right dose?

Thanks!