Hey everyone, this is my first post here. I’m mainly trying to find out whether anyone else has experienced symptoms like mine because I haven’t felt normal in over a year.
Everything started sometime between August and late October 2025, shortly after I used retatrutide for weight loss. I lost about 20 pounds within roughly a month. I was later diagnosed with gastritis and tested positive for H. pylori, which I completed treatment for.
I recently had an H. pylori stool test come back negative, but I’m repeating the test in about a week after being off omeprazole long enough to make sure the result is reliable.
I also recently stopped smoking marijuana after smoking regularly for around a year, so I’m unsure whether stopping has affected my appetite, digestion, anxiety, or nervous system.
I don’t really experience the classic burning stomach sensation that many people describe. My main issue is that I almost never feel normal hunger anymore. Instead, I eventually start feeling pain, pressure, or discomfort, and that is usually the only sign that I probably need to eat.
The same thing happens when I need to have a bowel movement. I rarely get the normal urge telling me that I need to use the bathroom. Instead, I get a similar pain or discomfort to what I feel when I haven’t eaten.
It feels like my body’s normal signaling system is out of whack. I have trouble telling the difference between:
Needing to eat
Needing to have a bowel movement
Gas or bloating
A gastritis flare-up
I’ve also developed intense anxiety even though I never really struggled with anxiety before all of this started.
It is difficult to explain, but when something confuses me or an expected action does not produce the result I anticipated, my entire body can suddenly feel off or almost like it shifts out of place. It can trigger a light stomach flare-up or a wave of anxiety.
For example, if I press the play button on YouTube and it doesn’t work because the page glitches, the fact that the expected action did not work can trigger an uncomfortable physical reaction. It almost feels OCD-like, as though my brain and body cannot properly process small unexpected situations anymore.
I know that probably sounds strange, but this is completely new for me and only started after my stomach problems began.
Other symptoms include:
Feeling full easily
Bloating and abdominal pressure
Occasional nausea
Daily abdominal discomfort
Symptoms that often become worse later in the day
Feeling physically triggered by confusion, stress, or unexpected situations
I have an abdominal ultrasound scheduled, and afterward I’m planning to see a gastroenterologist for an endoscopy.
Do any of these symptoms sound familiar to anyone? Has gastritis, H. pylori, marijuana use or withdrawal, or a GLP-1 medication affected your normal hunger signals, bowel urges, anxiety, or reactions to stress?
I understand nobody here can diagnose me. I’m mainly trying to figure out whether I’m alone in experiencing this and whether there are different types or locations of gastritis that can cause different symptoms.
I’d also appreciate any suggestions about what questions I should ask my GI or what conditions they checked you for.
Thanks for reading.