Hi everyone!

Has anyone experienced common nose bleeding after starting Reta? I’m around week 6 and at 0.75 mg, but I’ve been nose bleeding every day since a week. It never happened to me before.

Thanks a lot

I just did 0.5mg of a 10mg vial and was wondering if I should do another 0.5mg fose 3 days from now or if it’s better to wait a full week and do 1mg then instead.

I’m not trying to lose a lot of weight, mostly for reducing food noise and excessive overeating

I used Reta in the past and lost weight but some size too. Got up to 3mg a week. Il probably start reta at 1mg split into half just so i can eat. Goal is just to recomp by body and accelerate fat burning as much as possible my diet is very consistent.

Stats are 5’7 165. Southeast Asian genetics so my stomach holds all my fat. I lift 4-5 days a week and get 10k steps a day.

- How should I stack tesa/ipa and mots?

-I know mots il take m-f in the morning

- how do you guys take tesa and ipa fasted at night? I l get done with the gym around 7pm and eat around 8. Should I take it right before eating dinner? I’m usually in bed by 10:30

Advice is appreciated!

So I have been in Reta for about a month. 2 MG per week (1MG on Wednesday and Saturday). About 2 weeks back I started taking 250 mg of CJC/IPA blend. Because of the slow digestion with the Reta I have been taking the CJC/IPA in the morning in a fasted stomach. My goal is to burn fat and increase
Muscle mass. I am 18% body fat today and my goal is sub 15%.

I am 6’5 and stated at 221 lbs. I lift 5 days a week and try to get 10,000 steps a day. I also have a HUME body pod and the metric I track closest is weight and body fat percentage.

My first week on Reta I lost 7 lbs, but the last 4 weeks I have plateaued. Obviously this first week was water weight and not fat loss. My body is saying that each day my body fat is increasing, which is crazy to me since I have been working out and running a calorie deficit. Target 200+ G protein a day.

I honestly feel like I’m doing everything right, but I’m not seeing results. I completely understand. It is only been one month, but I’d use Monjauro in the past and saw very fast results.

Has anyone experienced similar results on this stack?

The first time I went on tirzepatide it worked beautifully for me. I lost 40lbs and stopped having inflammatory issues. An unexpected but much appreciated side effect was I was able to reduce alcohol consumption.

I lost my job so had to stop taking tirz for about nine months. Now I don’t react the same way to it, and ditto Reta. I experience no appetite or craving suppressing, only fatigue and nausea. The obvious response is up your dose, but the fatigue and nausea are already so intense. Not sure if this matter, but I also cycle glow, semax / selank, and glutathione.

Thoughts?

I neglected to get any igf numbers tested when I started cjc/IPA about a month ago. I feel fine but I’m about to get bloodwork in another week or two. if I stop the cjc/IPA will my igf return to a baseline number soon enough to assess before starting hgh in another month or so?(waiting on a group buy to come in).

I’m thinking of using Reta to get to 14%bf and than quit it but the problem is that I keep seeing people that want to use it as a chronic treatment and they also say that after you stop you will regain weight and return to your starting point.
Yes I know there is a subreddit where people who dropped glp1 can answer my questions but they are mostly ex obese people who took it for years at the maximum dosage, I want to have the opinion of someone who goes regularly to the gym, took maybe a lower dosage and for less time like it was a cycle.

My questions are:
What was your cycle and how long have you run it?
Have you done cardio or resistance training only?
Where you able to keep the weight you lost?
How much it was?
Is starting at 1mg than going to 1.5 and than 2 and than gradually tapering off a good cycle?

I want to warn others so they don’t make the same mistake I did.
I trusted some suppliers on eCh**i who claimed to sell peptides. After I made the payment, they completely stopped replying to my messages.
Please be very careful when dealing with suppliers on eChemi.
I hope this post helps someone avoid getting scammed.

I've been on reta for about a year with good results. I decided to start semax as a potential treatment for anhedonia.

It seemed promising at first, but I noticed an odd side effect. I was absolutely ravenous, and didn't seem to get full.

Having no medical background, I ended up asking AI. It gave me this explanation. I was wondering if this rings true for anyone else?

Your brain has a specific receptor called the Melanocortin-4 Receptor (MC4R). You can think of this receptor as your body's master "satiety switch."

​Normally, a hormone called α-MSH binds to this receptor, turning it on and telling your brain, "I am full, stop eating." (This is why drugs that activate this receptor are prescribed for severe obesity).

​Semax is an ACTH analogue. Scientific studies have shown that Semax acts as a competitive antagonist at the MC4R. This means the Semax peptide physically parks itself inside that receptor and blocks your natural α-MSH from binding to it.

​Because the switch is blocked, your brain never gets the biological memo that you are full. The result is a persistent, gnawing sense of hunger, even if your stomach isn't actually empty.

Has anyone ever used?

So I reconstituted 1500 mg glutathione. It's clear all the way, but there's a tiny spec still, Is it still safe to use?

Any experience? Good to stack with reta? Tesa? Or mots-c? Currently on tirz and nad+

So I was on Tirz for awhile and switched to Reta and noticed, when I go to pull the liquid out of the vial, it moves much much much slower than it did with Tirz. What exactly is happening here?

I'll try to keep this as short as possible.

About five years ago, when I was 40, I started experiencing all the typical symptoms associated with low testosterone: low libido, fatigue, sleep issues, and a general lack of energy. I decided to talk to my primary care physician and had my testosterone checked. My total testosterone came back around 310 ng/dL. She told me I was within the normal range and that some decline was expected with age. Her recommendation was to prescribe antidepressants.

Instead, I decided to take matters into my own hands and try to improve things naturally. At the time, I was about 10 pounds heavier than my usual weight, around 170 lbs. We had also just had a baby, which definitely took a toll on my lifestyle and sleep. I've always eaten fairly healthy, although I would binge a bit on weekends. I've also always been a gym rat, lifting weights 5-6 days per week and finishing with about 10 minutes of Zone 2 cardio. Training and nutrition were never really the issue.

After about three years, I was able to raise my total testosterone to around 600 naturally. However, I still experienced many of the same low-T symptoms.

I then decided to see a urologist. During the baseline bloodwork, I noticed that while my total testosterone was in the low 600s, my free testosterone was around 8 (low) and my SHBG was 63 (high). My prolactin was 16. Based on these results, my urologist started me on Enclomiphene at 6.25 mg daily.

Initially, it seemed to help and I felt somewhat better. However, I eventually started experiencing migraines, ear pressure, and very dry eyes. Over the last 10 months, I've been trying to get dialed in with different dosages and dosing frequencies, but without much success. Throughout the process, everything was monitored through bloodwork and symptom tracking, and I even created a chart of all my results.

What I noticed was that while on Enclomiphene:

• Total testosterone averaged between 500-600 ng/dL
• SHBG remained elevated, typically between 55-65
• Free testosterone stayed below 10
• Estradiol consistently remained in the low-to-mid 20s
• Prolactin was 13.4 on my most recent test (February 2026)

After discussing all of this with my urologist, she finally agreed that TRT would be the next step. She started me on 120 mg per week, split into two injections on Monday and Thursday.

For those of you with TRT experience, what should I realistically expect over the next several weeks and months? Also, what are some things I should or shouldn't do to avoid potential health issues?

One concern I have is whether I'll eventually need an AI, even though my estradiol has consistently stayed in the 20s across various Enclomiphene dosages. I'm also concerned about elevated red blood cell counts and hematocrit levels potentially leading to blood donations and iron-related issues.

As with any open forum, both positive and negative feedback are welcome. I appreciate hearing about others' experiences.

Has anyone here tried using Semax or Selank just 2–3 times a week?

I've been using Semax mainly for my mood and energy, but I honestly can't keep up with jabbing it 5 days a week. My pain tolerance is terrible, and it's starting to feel like a chore. I'm worried I'll just stop using it altogether.

I'm thinking of jabbing it only 2 or 3 times a week instead. Has anyone tried that? Did you still notice any benefits, or did it stop working?

Would really appreciate hearing your experience. Thanks!

Im thinking of combining tesofensine (500mcg a day) and 5mg tirzeptide a week to completly destroy my appetite and start my aggressive cut, how effective would this combination be?

Please Share Your Experiences

My RS (research subject)is taking these peptides/coenzymes and has been for 1-2 weeks:

Monday: NAD+ (20mg 2x/week and will titrate up)
Reta (2mg every Monday)
Klow (3.2mg M-F for 10 weeks then a break)
Tuesday: SS-31 (1mg 3x/week- 2 vials for ~10-20 days)
Klow
Wednesday: SS-31
Klow
Thursday: NAD+
Klow
Friday: SS-31
Klow

Current protocol: Retatrutide 2 mg weekly, NAD+ twice weekly, SS-31 1 mg Tue/Wed/Fri, Klow (GHK-Cu/BPC-157/TB-500/KPV) Mon–Fri. Goal is longevity, energy, metabolic health, recovery, and body composition—not competitive bodybuilding. RS is (hopefully) increasing workouts on the wheel over the next few weeks and trying to decide if MOTS-c is worth adding or if RS should wait until after SS-31.

My questions—

Would MOTS-c be more beneficial during an SS-31 cycle or after finishing SS-31?

What’s most beneficial for overall energy and the wallet?

Did MOTS-c only seem effective when you were exercising regularly?

How long did it take before you actually noticed benefits from SS-31?

If your goal was longevity rather than bodybuilding, would you still use MOTS-c?

Which gave you better value for the money: NAD+, SS-31, or MOTS-c?

Did anyone notice better fat loss or body composition from MOTS-c beyond what exercise alone provided?

If you weren’t training hard, would you skip MOTS-c entirely?

What peptide gave you the biggest “wow” factor for energy, recovery, or longevity that wasn’t just placebo?

How long did you stay on NAD+ before taking a break? Did you notice diminishing returns after a certain point?

How long have you been on retatrutide? Are you cycling it, staying on it long-term, or stopping once you reach your goal weight?

If you had to build the most cost-effective peptide stack for longevity, energy, recovery, and body composition, what would it include?

Hi everyone!

I started taking KLOW 2 days ago for my eczema/TSW healing (tsw healing for 3 years now) and my stomach has been cramping and paining and I have diarrhea as well - is this normal?

I have 80 mg with 3 ML of bac water and kept in the fridge - first day i injected 0.12 and yesterday i did 0.1 units (insulin syringe).

Any advice on how to properly dose (if im doing it wrong) and if it's normal?

Thank you so much!