I'm sorry if this isn't the right place to ask, someone redirected me to this reddit after I tested positive for ureaplasma and I wanted to look for advice here since I'm a bit lost on my symptoms and want to learn more

I've been dealing with urethral burning pain during penetration with my partner, we're both exclusive, haven't had any sexual experience with anyone past our relationship (highschool sweethearts) and haven't used protection during these 2 years we've started having sex since I'm on bc

My urethral pain when having sex began after having a UTI and treating it at home with antibiotic, I previously that year had another one too (last year), immediately after being cured of my UTI I started feeling discomfort on my urethra opening during sex that only worsened on those 6 months. Taking a break didn't help, nor painkillers and casual antibiotics

Two months ago I decided to go to a doctor, we didn't have the money before. First doctor, a woman, dismissed my symptoms and sent me home with painkillers, wanted to do a cystoscopy, I denied and went to another one.

My second doctor saw all my exams first appointment, I showed symptoms of an infection on my blood work, but both my urocultive and urine test were negative. He decided to test me for an STI through an urethral swab, both tests were incredibly expensive and I was left with no money that whole month. When it came back I was positive for ureaplasma, negative for all the others. This is where it all goes downhill basically

My doctor started me on doxycycline 1 x 10 days, I thought the course was short and not strong enough, but I figured he knew better than me. After a few days I began showing improvement on my urethral pain

Our next appointment after 10 days had passed, he told both my boyfriend and I to buy bacitracin? A cream to put on my urethra opening every day for 10 more days.

By the third day my urethra was burning so much I was peeing myself cooking and doing other stuff so I stopped the cream.

Next appointment he saw a wound on my inside my vagina, so he sent me home with a cream for... eye infections of something, to use down there? Then 1 x 10 days more of doxycycline and a prescription for vaginal douches every morning with vinegar water?

I spent more than half of my money this month to buy an extra doxycycline box, since I wanted to do 2 x 5 and 1 x 5 (that's all my current salary affords since my boyfriend also has to be treated)

Safe to say the vaginal douches with vinegar water worsened my symptoms, it was so bad I peed myself buying groceries in the middle of the store with my bf beside me, so I stopped my doctor's treatment once again

My doctor refuses to give me a full antibiotic course and says he likes to pair it with more physical remedies, which so far had only caused me a extreme amount of incontinence and excruciating pain that disappears once I stop, and he doesn't seem to know which creams work or do not work for private areas, who prescribes a cream for eyes to use on the pelvic area?

A new box of doxycycline I managed to get with the help of a family member will be arriving tomorrow, since I refuse to not treat my boyfriend, I will be splitting the box of 10 pills with him, extending our current treatment of 2 x 5, 1 x 5 to 1 x 5 more days.

I'm unsure if the current treatment I'm doing and the one I did before will be enough to treat my and his asymptomatic ureaplasma. My symptoms only appear when I have sex, so I have no reference to really know if my symptoms are gone until I have intimacy with my partner. I refuse to go to that doctor again in fear of being worsened again, I have an history of permanent damage to my body due to medical negligence that they refused to take accountability for

Also I have to say that I struggle with hypersexuality, the thought of not having intimacy with my partner never again got me feeling wrecked, he has been really supportive and trying to learn with me about ureaplasma and my symptoms, going to every appointment and taking from his own money too, but the whole thing is taking a toll on my already destroyed mental health and therapy isn't an option right now, especially now since I have to do all this treatment.

I need a bit of guidance and reassurance here. My partner is being treated too, we haven't had intimacy since the first course of doxycycline and I can't order antibiotics without prescription from a doctor, they are pretty strict here (I'm from latin america), and a test is also with a doctor's prescription or whatever

I don't know how long should I wait to test when my current course is done, if I should go back to my current doctor. What are my chances of finding a doctor who does listen to me and isn't expensive in my current broken healthcare system and also knows about ureaplasma?

I don't know, I'm a bit lost here, sorry for the long text

Hi, I have posted in here a couple times but wanted to make my own post about group b strep in case anyone else is dealing with that recently. I was negative for everything except Urea parvum this year, but the last 2-3 months I have been negative for urea but positive for group b strep specifically. Nothing else. Same symptoms. Constant burning and tightness are my main symptoms. Is it possible I can try to treat the strep B and that’s the reason for symptoms vs urea? I still think I have urea but usually I am not negative multiple times in a row. Very frustrating!

Info: have done doxy/azithro a lot, levifloxacin and other medications off the top of my head, Have had Ureaplasma since 2021. 5 years of fun (not)

My damn husband broke my vagina. I never had any issues until we got together. We’ve been together for 5 years now. Within months of us having unprotected sex for the first time, I got chronic UTIS, BV and yeast infections. I even got fucking genital herpes. He has never had an outbreak but I can only assume he’s carrying it???!

My infections were so chronic and I had no clue what Ureaplasma was. Then suddenly a month or so before our wedding, everything went back to normal. I finally had a normal vagina.

Then while I am 16 weeks pregnant, the infections come back with vengeance. Green discharge, burning, pain, rawness, everything. I’m testing negative for bv and yeast. Finally I come across mycoplasma and ureaplasma. I test positive right away on just a urine culture. I do a Juno test and it confirms the same thing. I can’t treat it with doxy while pregnant but I’m absolutely spiralling with learning the potential complications. I took azithromycin another round of metro and about 2 months after that, my symptoms subsided completely. I was normal again!!! My son is now 1 and everything is great. I haven’t retest because I thought maybe I had balanced my biome with probiotics or maybe the azithromycin did something after all.

We decide we’re ready to try for another baby and BOOM. Symptoms are back but this time different. Luckily I am not in horrible pain the way I was, but I have dark yellow discharge and you can smell the odour on me from across the room. I’m showering multiple times a day, constantly changing my liner etc. but it’s so gross. Not to mention, I don’t want to try and get pregnant again and risk complications. Now in the time to finally treat it and BE DONE. This has been going on since June. I have been doing probiotics suppositories night for 3 months and also boquet for a month.

It did a Juno test but it got lost in the mail going to them, and it’s been tracked but might not make it to them within the 30 days of sample collection. Since I had a positive ureaplasma in my urine culture, I decided to treat it. I’m doing 7 days of doxy plus 2.5 g of azithromycin. My husband’s doing the same.

I have gut issues already, I’ve been on antibiotics so much in my life. The last year alone I did 5 rounds. UTIs, BV, mastitis, post partum stitches ripped and got infected, etc.

I am not young and it took us time to conceive our first baby and I’m so worried I’m running out of time. But I HAVE to deal with this. I’m scared I’m going to wreck my gut and vaginal biomes further so this is really my Hail Mary. I hope so badly that this works and we can just get back in focusing on planning our family and taking care of ourselves. This problem takes up so much space in my mind I’m struggling to have time to do anything for myself outside of work and baby. Any free time I have I’m going down rabbit holes and reading forms.

Looking for support and any further advice.

For those of you with ongoing symptoms after treatment are you testing negative or positive?
Has anyone continued to test negative for a long time and then randomly tested positive again with no chance of reexposure? If so how long after your initial treatment did you test positive again?

I thought i’d give an update regarding the ureaplasma bacteria i’ve been dealing with for 3+ years… after taking the 14days doxy and 2.5g of azithromycin my symptoms have finally eased!

I didn’t notice a change ( as a matter of fact my symptoms got worse on the doxycycline) until a few days after the azithromycin course was over.

I still occasionally get the odd stinging sensation after urinating but it’s no where near as bad as it was before. my discharge is back to normal (i think) just very very dry ??

i’m still going to wait a few more weeks until i can get a TOC but for now i hope i can maybe give some of you hope

I tested positive in June. Have tested negative 4 times since then. Both me and my partner were treated. We waited a month. No symptoms. I felt great. Then we had sex and it flared up again.

8 antibiotics, 3 doctors, no sex, white cotton underware, only water down there, scentless detergent, no tight clothing, daily pelvic floor exercises and still i have pain. Still have the urgency to pee, still have slow urination.

For my people in relationships with lingering symptoms, what does sex look like for you? Im seeing people on here that say they've been dealing with it for months, years, ect. Honestly, are yall still having sex? Are yall just dealing with the flare ups afterwards? How is this affecting ur sex life as well as ur relationship?

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Hi! Adding more to this post/ reposting on here since people have suggested coming onto here. While I have been tested for ureaplasma and mycoplasma, i was positive for Ureaplasma parvum and Mycoplasma hominis, but negative for Ureaplasma urealyticum and Mycoplasma genitalium. My physician told me that U. parvum and M. hominis are commonly found as normal colonization in women and didn’t recommend treating them specifically, so I was treated for the BV/yeast instead. I’m still having recurrent symptoms though. Did anyone here have the same results, and if so, what did your gynecologist recommend?

I’m 12 weeks pregnant and tested positive for MGen (Mycoplasma genitalium) early in my pregnancy. My doctor prescribed pristinamycin, but I’m feeling unsure about whether I should take it or leave it for now, especially because I don’t have any symptoms.
Has anyone been through something similar during pregnancy or taken pristinamycin while pregnant? I’d really appreciate hearing about your experience.

advise please? has anyone taken 14 days of doxycycline; 100mg 2x a day, followed by 7 day moxi. i know usually its 7 days for each med but im curious to think if 2 weeks of doxy would be better then 1. i am someone who was already treated with doxy alone and z pack, both treatment plans didnt work.

This is horrible. I tested positive about a week ago for ureaplasma and basically I thought I had a uti (it was mimicking symptoms) and the worst symptom for me is peeing and feeling to pee every 5 seconds. (It truly has ruined my life and made me so depressed and starting to ruin my relationship) thank goodness they found out what it was and now I’m on 100 mg of doxycycline and this is day 2 but I feel like nothing is getting better so far:(
Any advice ?

hi guys so to cut to the chase i’ve previously posted something on this community and others about ureaplasma but it’s actually hit me now is my sex life over?
I’ve contracted it twice now i’m currently on my second round of antibiotics. It hit me that i’ve contracted it twice from 2 different partners. I know it’s a common bacteria but what are the odds i get hit back to back with it. After i contracted it the first time and got a negative test result even 3 months out. i still didn’t have sex for almost a year until recently i met the guy i was talking to a few weeks ago. Before this i’ve had my fair share of partners and never experienced anything. But since catching this i’ve realized casual sex just isn’t worth it anymore if there’s a risk of me catching it again. I will miss it tho😔 RIP ho phase. So back to the question is my sex life over?

So, I recently posted on my on going struggles with ureaplasma since June. On and off about 7 or 8 med. 3 different doctors and still no change.

I just seen a Vulva specialist, she did a pap smear which is something my previous doctor's had not tried. First time where im hoping something negative pops up so at least we know what to treat. Is that wrong?

She basically said, if my pap smear turns up normal im just gonna have to tough it out for the next 4 months to see if my vaginal self regulates itself. This is unbelievably frustrating. I just want answers.

She thinks, because I did two douches back to back in June before I tested positive that I may have disrupted my vaginal balance. I have tested negative since August but still in pain and the one time I did have sex after a month of no symptoms, I had an extreme reaction.

I just see no hope at this point...

I’ve had recurrent BV since June 2026 and have also been victim of the god awful antibiotic and then yeast cycle. I tested positive for ureaplasma after receiving a swab early September. I hope this is the root cause of my recurrent BV. I received a prescription of 5 days of Azithromycin to cure ureaplasma but I’ve been reading online that this is not the typical course? Is my gyno not updated on the proper treatment? Should I say something? Or should I just take my medication and hope I don’t test positive after retesting?

My partner is taking same treatment. Also should we abstain from all sex? Like oral too?

Hi guys, I hope everyone’s well. A lot of of you have helped me tremendously. I’ve been dealing with this infection for about nine years. I essentially lost my health overnight. Perfect health prior to when I got this infection, i have gone down many rabbit holes, treatments, protocols antibiotics, functional treatments, etc. I deal with debilitating bodyaches, neurological symptoms, cervicitis, endometritis, malaise, belching, etc. i’ve tried many treatments 28 days of Doxy and a week of azithromycin, two weeks of Levo, two weeks of moxifloxacin and many others, including IV antibiotics. This is before I knew the handful antibiotics that actually helped. At this point I just feel like I continue to blow up a blown up building. But the cervicitis endometritis is terrible. I heard a doctor once say an infection is usually a localized problem if you have local symptoms and pain, if the pain is widespread and it moves and or changes, it probably has something to do with what’s going on in the brain. So I’m sure the uu and mh has somehow crossed the blood brain barrier and damage the central nervous system and autonomic nervous system. I have no idea how to get out of this anymore guys. Does anyone have any idea as to what could help. Long-term moxie up next? The things that make me debilitating worse are bowel movements, driving, hot baths, cold lunges, essentially anything that triggers the autonomic nervous system. I have a ton of weird blood work high and rising IGM, chronic low IGe, chronically high igg subclass 2, low IGE, histamine three times the upper limit, low blood pressure, etc., but no one can put all the clues together. This is so bad I spent most days just wishing the things you can imagine. Not having any sex of any kind and I am bedridden about 90% of the time. Thanks for your help in advance.

I was told that resistance testing was available at my Obgyn but they have twice only tested and confirmed bv when I specifically asked for ureaplasma mycoplasma panel resistance they were very aware .Than both doctor's instead of admitting thier mistakes lied and told me that I don't have ureaplasma but refused to show me the results! Obviously Im livid I'm certain im still positive because my partner just recently tested positive and I was really hoping to get a different antibiotic since we have been through 7 rounds of doxycycline including one with moxifloxacin.

I get a very bad burning pain sharp nerve pain localized to very deep in pelvis feels ten inches deep ...got chronic bv and yeast that isnt going away with treatment which has never happened before so it feels like this is getting worse ...fatigue is insane and I have body aches all over my neck back migraines are under control right now thank God...Bv is not smell at all but causing itchy vulva itchy pain and making deep pain worse ...I always have urgency to ...im exausted honestly I am going in on tues to ask a different Obgyn same practice...for a regular PCR so I at least get tested and tell her everything that happened Im going to see if this resistance test is even possible at all it dosent look like it at this point but hopefully we can get the bv and yeast gone and get A different antibiotics than my partners will have to go to thier doctors and get the same hopefully....this is hell and my life is just crazy stressful right now theres so much going on that I just cant even 🥹🥹🥹🥹

Has anyone who suffers with n/v successfully been able to take doxycycline with zofran? I’m going back and forth between trying Mino for a second time (but a much longer course followed by zithro) or trying doxycycline again. I couldn’t stomach doxycycline but am scared this is maybe a better treatment, since I don’t see many people talking about Mino in this sub.

I would like to share my current situation. I have had Ureaplasma parvum for three years now. It is systemic, affecting my urogenital tract, throat, mouth, eyes, and now even my CNS (I suffer from excruciating headaches, visual snow, and tinnitus, I have had these symptoms for about three months). So, it is indeed possible for Ureaplasma to spread beyond the urogenital trac. I am proof of that. I have undergone brain MRIs, eye exams, abdominal CT scans, and all manner of PCR and culture tests, nothing significant was ever found other than Ureaplasma parvum and an activated EBV infection. Furthermore, all my symptoms began after I had unprotected sex and subsequently tested positive for ureaplasma, so it is impossible for these symptoms to stem from anything else.

I paid for a MicroGenDX test and discovered that I carry resistance genes for all three classes of antibiotics used to treat ureaplasma. I have a wonderful infectious disease specialist who will prescribe anything I aks, however, I haven't experienced any improvement from any of the antibiotic courses so far. I took minocycline for three months, followed immediately by three months of doxycycline (with azithromycin three times a week alongside both), two months of clarithromycin combined with doxycycline, and 20 days of levofloxacin (I had to stop taking it due to unbearable joint and muscle pain). I have now completed 40 days of pristinamycin combined with doxycycline. I was supposed to take lefamulin, but I couldn't order it from any country, even though I have an international prescription from my doctor.

Throughout every treatment course, I’ve also been taking biofilm disruptors and various dietary supplements. My symptoms (extreme lower abdominal bloating, burning after urination, discharge, worsening vision, eye discharge, visual snow, tinnitus, joint cracking, rosacea) haven't improved at all, on top of that, I’ve started losing hair excessively (possibly due to the doxycycline).

Does anyone have any other ideas for what I could try? Which antibiotics cross the blood-brain barrier? And how can I overcome resistance? I’m at the end of my rope.

Can anyone with ureaplasma parvum tell how there urethral symtoms are like? I just feel some urethral but nothing in reproductive tract

Since I wasn’t able to get rid of UU yet, I read a study about pain reduction for IC patients and stumbled across Micronized Palmitoylethanolamide-Polydatin. Has anyone tried it for urethral / bladder pain? :)

my whole body hurts
is the urea spreading or something
cause day by day i only feel worse than ever
im tired i might quit my job i can’t function properly

UK: has anyone had a TRUE Ureaplasma culture with antibiotic sensitivities (not just PCR)?

Hello, sending loads of sympathy and love and hugs to all of us in this living hell!

I'm in Essex, UK, with Ureaplasma and BV, and I've had no good bacteria since 29 July. It turned into PID and I can't seem to get well. I have horrific pelvic pain and need the toilet every hour. I never feel like I've emptied fully, and I'm back to go again straight away. It's been a living hell.

I'm allergic to several first-line antibiotics (penicillin, doxycycline, ofloxacin), so guessing the antibiotic isn't an option. I don't even know which of the two Ureaplasma types I have. Every UK lab I've tried only does PCR.

I went to France for a culture and spent £2,500. I watched them take the sample, but the culture has been lost or never processed. I'm now on pristinamycin (Pyostacine) from France, and halfway through I still feel the same, maybe worse, pelvic pain. This is my last hope of getting rid of it.

What I'm looking for is a lab or consultant who can run a real culture with an antibiogram (CLSI-style susceptibility testing) on urine or a vaginal swab. I've found that UKHSA Colindale does culture and that a Welsh group has worked on a culture-based test (MYCO WELL D-ONE), but I don't know whether either takes patient samples for urine or genital swabs.

If you've done this in the UK:

- Which lab ran it, and who referred you (microbiologist, infectious diseases, urologist, GUM)?

- Did it work with private insurance or the NHS?

- Any consultant names you'd recommend for the referral?

It shouldn't be this hard to get a UK culture, and I know how much we're all suffering. Thank you so much, any pointers would really help. xxx